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2,114 Results Found

  • Article
  • Open Access
4 Citations
1,787 Views
16 Pages

10 November 2024

The pre-release operation has the potential to enhance the ability of a reservoir to manage exceedance floods. However, the mechanisms for the initiation and termination of such operations are unclear, and a clear method for calculating the pre-relea...

  • Article
  • Open Access
7 Citations
2,173 Views
15 Pages

Stability Index of Surrounding Rock during Deep Rock Excavation Considering Energy Release Speed

  • Sheng Luo,
  • Peng Yan,
  • Wenbo Lu,
  • Zhihong Dong,
  • Chunhua Zhou,
  • Zhaowei Yang and
  • Yingguo Hu

26 February 2023

Rockburst is a kind of dynamic rock failure process that is easily induced by the excavation of a high-stress rock mass. However, from an energy perspective, the existing indexes for rockburst tendency have a limitation in that they do not consider t...

  • Article
  • Open Access
16 Citations
2,919 Views
15 Pages

A New Bursting Liability Evaluation Index for Coal –The Effective Elastic Strain Energy Release Rate

  • Zhiguo LU,
  • Wenjun JU,
  • Fuqiang GAO,
  • Youliang FENG,
  • Zhuoyue SUN,
  • Hao WANG and
  • Kang YI

30 September 2019

Because both faults and cleats exist in coal, sharp stress drops occur during loading when coal is deformed. These drops occur during the pre-peak stage and are accompanied by sudden energy releases. After a stress drop, the stress climbs slowly foll...

  • Article
  • Open Access
1 Citations
2,457 Views
15 Pages

Processing of Legume Green Manures Slowdowns C Release, Reduces N Losses and Increases N Synchronisation Index for Two Years

  • Monika Toleikiene,
  • Ausra Arlauskiene,
  • Skaidre Suproniene,
  • Lina Sarunaite,
  • Gabriele Capaite and
  • Zydre Kadziuliene

5 March 2024

The number of livestock farms decreased by 40% in Europe over the last 10-year period. Stockless organic cropping systems started to dominate in many intensive agricultural regions in Europe. Developing the sustainable management of an organic stockl...

  • Article
  • Open Access
17 Citations
64,070 Views
15 Pages

15 July 2020

The fire growth rate index (FIGRA), which is the ratio of the maximum value of the heat release rate (Qmax) and the time (tmax) to reach the maximum heat release rate, is a general method to evaluate a material in the fire-retardant performance in fi...

  • Article
  • Open Access
15 Citations
7,463 Views
9 Pages

Glycemic Index of Slowly Digestible Carbohydrate Alone and in Powdered Drink-Mix

  • Vishnupriya Gourineni,
  • Maria L. Stewart,
  • Rob Skorge and
  • Thomas Wolever

29 May 2019

Consumer interest in food and beverages with carbohydrates offering steady glucose release and lower glycemic index (GI) continues to rise. Glycemic index is one of the metrics for carbohydrate quality. Slowly digestible carbohydrates (SDC) offer an...

  • Article
  • Open Access
4 Citations
6,233 Views
17 Pages

Development and Evaluation of Gelatin-Based Gummy Jellies Enriched with Oregano Oil: Impact on Functional Properties and Controlled Release

  • Mariana Ganea,
  • Potra Cicalau Georgiana Ioana,
  • Timea Claudia Ghitea,
  • Liana Ștefan,
  • Florina Groza,
  • Olimpia Daniela Frent,
  • Csaba Nagy,
  • Claudiu Sorin Iova,
  • Andrada Florina Schwarz-Madar and
  • Gabriela Ciavoi
  • + 3 authors

2 February 2025

Functional foods play a crucial role in contemporary dietary strategies. This study investigates the incorporation of oregano oil, a bioactive extract that is known for its antimicrobial and antioxidant properties, into gelatin-based gummy jellies to...

  • Article
  • Open Access
6 Citations
3,642 Views
13 Pages

10 March 2024

The use of a two-stage combustion system in a hydrogen-fueled engine is characteristic of modern internal combustion engines. The main problem with hydrogen combustion in such systems is knocking combustion. This paper contains the results of researc...

  • Article
  • Open Access
4 Citations
4,273 Views
17 Pages

Asbestos Hazard in Serpentinite Rocks: Influence of Mineralogical and Structural Characteristics on Fiber Potential Release

  • Lorenzo Marzini,
  • Marco Iannini,
  • Giovanna Giorgetti,
  • Filippo Bonciani,
  • Paolo Conti,
  • Riccardo Salvini and
  • Cecilia Viti

Naturally occurring asbestos (NOA) represents a matter of social and environmental concern due to its potential release in the atmosphere during rock excavation and grinding in quarry and road tunnel activities. In most cases, NOA occurs in serpentin...

  • Article
  • Open Access
6 Citations
2,880 Views
14 Pages

11 May 2023

Thermal behavior and fire reaction properties of aerial glass fiber (GF)/bismaleimide (BMI) composites were tested using thermogravimetric analysis (TGA), thermogravimetric coupled with Fourier transform infrared spectroscopy (TG-FTIR), cone calorime...

  • Article
  • Open Access
2 Citations
1,995 Views
29 Pages

The ICP-MS Study on the Release of Toxic Trace Elements from the Non-Cereal Flour Matrixes After In Vitro Digestion and Metal Pollution Index Evaluation

  • Jiří Nekvapil,
  • Karolína Vilišová,
  • Zdeněk Petřík,
  • Erkan Yalçin,
  • Miroslav Fišera,
  • Robert Gál,
  • Richardos Nikolaos Salek,
  • Martina Mrázková,
  • Martina Bučková and
  • Daniela Sumczynski

14 April 2025

Detailed research analysis of the contents of eight toxic trace elements in non-cereal flours was conducted using inductively coupled plasma mass spectrometry, and the release of elements from the flour matrixes after in vitro digestion was investiga...

  • Article
  • Open Access
125 Citations
10,693 Views
21 Pages

The short term stability of efavirenz-loaded solid lipid nanoparticle and nanostructured lipid carrier dispersions was investigated. Hot High Pressure Homogenization with the capability for scale up production was successfully used to manufacture the...

  • Article
  • Open Access
2 Citations
1,976 Views
17 Pages

26 April 2024

The pouring of sand casting is accompanied by severe heat conduction, and there is an urgent need to investigate the pyrolysis properties of foundry sand. The main purpose of this study was to investigate the pyrolysis behaviors of resin sand, includ...

  • Article
  • Open Access
16 Citations
5,575 Views
13 Pages

14 September 2018

Despite the great progress in the field of drug delivery systems for cancer treatment over the last decade, many challenges still lie ahead, such as low drug loading, deep penetration of tumors, side effects, and the development of drug resistance. A...

  • Article
  • Open Access
4 Citations
4,056 Views
12 Pages

14 January 2022

Gonadotropin-releasing hormone agonist (GnRHa) therapy is used to control puberty progression and it preserves height potential in patients with idiopathic central precocious puberty (ICPP). This study evaluated the correlation between weight and hei...

  • Article
  • Open Access
2 Citations
1,598 Views
14 Pages

7 March 2025

Introduction: Cytokine release syndrome (CRS) and immune cell-associated neurotoxicity syndrome (ICANS) are both serious complications of CAR-T therapy associated with endothelial dysfunction, prompting prior use of a modified version of the endothel...

  • Article
  • Open Access
8 Citations
2,590 Views
16 Pages

14 March 2021

In this work, a methodology that exploits the optical properties of the nanoporous anodic alumina gradient index filters (NAA-GIFs) has been developed and applied to evaluate in real time the release dynamics of a cargo molecule, acting as a model dr...

  • Article
  • Open Access
54 Citations
13,148 Views
21 Pages

15 February 2018

Overheating of buildings and urban areas is a more and more severe issue in view of global warming combined with increasing urbanization. The thermal behavior of urban surfaces in the hot seasons is the result of a complex balance of construction and...

  • Feature Paper
  • Article
  • Open Access
2,793 Views
8 Pages

Effects of Late Conversion from Twice-Daily to Once-Daily Slow Release Tacrolimus on the Insulin Resistance Indexes in Kidney Transplant Patients

  • Valeria Cademartori,
  • Fabio Massarino,
  • Emanuele L. Parodi,
  • Ernesto Paoletti,
  • Rodolfo Russo,
  • Antonella Sofia,
  • Iris Fontana,
  • Francesca Viazzi,
  • Pasquale Esposito and
  • Giacomo Garibotto

The use of tacrolimus (Tac) may be involved in the development of new-onset diabetes after transplantation (NODAT) in a dose-related manner. This study aimed to evaluate the effects of a standard twice-daily formulation of Tac (TacBID) vs. the once-d...

  • Article
  • Open Access
58 Citations
38,415 Views
24 Pages

27 August 2019

Despite major advances in numerical weather prediction, few resources exist to forecast wildland fire danger conditions to support operational fire management decisions and community early-warning systems. Here we present the development and evaluati...

  • Article
  • Open Access
14 Citations
5,620 Views
34 Pages

3 July 2020

Software maintenance is one of the key stages in the software lifecycle and it includes a variety of activities that consume the significant portion of the costs of a software project. Previous research suggest that future software maintainability ca...

  • Article
  • Open Access
26 Citations
8,718 Views
24 Pages

Application of Citizen Science Risk Communication Tools in a Vulnerable Urban Community

  • Yuqin Jiao,
  • Julie K. Bower,
  • Wansoo Im,
  • Nicholas Basta,
  • John Obrycki,
  • Mohammad Z. Al-Hamdan,
  • Allison Wilder,
  • Claire E. Bollinger,
  • Tongwen Zhang and
  • Luddie Sr. Hatten
  • + 2 authors

A public participatory geographical information systems (PPGIS) demographic, environmental, socioeconomic, health status portal was developed for the Stambaugh-Elwood (SE) community in Columbus, OH. We hypothesized that soil at SE residences would ha...

  • Article
  • Open Access
2 Citations
1,201 Views
19 Pages

Assessment of Fluoride Intake Risk via Infusions of Commercial Leaf Teas Available in Poland Using the Target Hazard Quotient Index Approach

  • Agata Małyszek,
  • Ireneusz Zawiślak,
  • Michał Kulus,
  • Adam Watras,
  • Julia Kensy,
  • Agnieszka Kotela,
  • Marzena Styczyńska,
  • Maciej Janeczek,
  • Jacek Matys and
  • Maciej Dobrzyński

24 August 2025

The objective of this study was to assess the content of selected elements—fluorine, calcium and inorganic phosphorus—in infusions prepared from selected commercial leaf teas available on the Polish market. A comprehensive analysis was conducted base...

  • Article
  • Open Access
5 Citations
2,995 Views
23 Pages

Octane Index Applicability over the Pressure-Temperature Domain

  • Tommy R. Powell,
  • James P. Szybist,
  • Flavio Dal Forno Chuahy,
  • Scott J. Curran,
  • John Mengwasser,
  • Allen Aradi and
  • Roger Cracknell

25 January 2021

Modern boosted spark-ignition (SI) engines and emerging advanced compression ignition (ACI) engines operate under conditions that deviate substantially from the conditions of conventional autoignition metrics, namely the research and motor octane num...

  • Article
  • Open Access
39 Citations
6,026 Views
20 Pages

Ultrasound-Responsive Smart Drug Delivery System of Lipid Coated Mesoporous Silica Nanoparticles

  • Muhammad Umair Amin,
  • Sajid Ali,
  • Imran Tariq,
  • Muhammad Yasir Ali,
  • Shashank Reddy Pinnapreddy,
  • Eduard Preis,
  • Christian Wölk,
  • Richard D. Harvey,
  • Gerd Hause and
  • Jana Brüßler
  • + 1 author

The immediate release of chemotherapeutics at the target site, along with no premature release in circulation is always challenging. The purpose of this study was to develop a stimuli responsive drug delivery system, composed of lipid supported mesop...

  • Article
  • Open Access
17 Citations
4,121 Views
21 Pages

Diatomaceous Earth—Lightweight Pozzolanic Admixtures for Repair Mortars—Complex Chemical and Physical Assessment

  • Milena Pavlíková,
  • Pavla Rovnaníková,
  • Martina Záleská and
  • Zbyšek Pavlík

3 October 2022

The presented research is focused on the complex assessment of three different types of diatomaceous earth and evaluation of their ability for application as pozzolana active admixtures applicable in the concrete industry and the production of repair...

  • Article
  • Open Access
5 Citations
2,753 Views
12 Pages

Soluble Urokinase-Type Plasminogen Activator Receptor (suPAR), Growth Differentiation Factor-15 (GDF-15), and Soluble C5b-9 (sC5b-9) Levels Are Significantly Associated with Endothelial Injury Indices in CAR-T Cell Recipients

  • Eleni Gavriilaki,
  • Christos Demosthenous,
  • Paschalis Evangelidis,
  • Zoi Bousiou,
  • Ioannis Batsis,
  • Anna Vardi,
  • Despina Mallouri,
  • Eudoxia-Evaggelia Koravou,
  • Nikolaos Spyridis and
  • Alkistis Panteliadou
  • + 9 authors

14 October 2024

Endothelial injury indices, such as Endothelial Activation and Stress Index (EASIX), modified EASIX (m-EASIX), and simplified EASIX (s-EASIX) scores, have been previously associated with chimeric antigen receptor-T (CAR-T) cell immunotherapy complica...

  • Article
  • Open Access
1 Citations
1,120 Views
20 Pages

Design and Experimentation on a Pneumatic Corn Seed Metering Device with Assisted Seed-Filling and Airflow-Guided Seed Release

  • Jiahua Yan,
  • Guangwei Wu,
  • Rui Liu,
  • Liwei Li,
  • Yuejin Xiao,
  • Junxian Guo and
  • Bingxin Yan

In view of the problem that the qualified index of grain spacing deteriorates during high-speed operation of the pneumatic corn seed dispenser, a new method of homologous dual-action positive-pressure-assisted seed filling and seed release is propose...

  • Article
  • Open Access
4 Citations
2,125 Views
14 Pages

18 December 2023

This study focuses on the increased risk of high heat release and asphyxiation (toxic gas poisoning) in the event of a fire involving polyurethane (PU)- and MDF-based building materials, which are commonly used in buildings. Among them, polyurethane...

  • Article
  • Open Access
63 Citations
6,360 Views
14 Pages

Gellan Gum/Pectin Beads Are Safe and Efficient for the Targeted Colonic Delivery of Resveratrol

  • Fabíola Garavello Prezotti,
  • Fernanda Isadora Boni,
  • Natália Noronha Ferreira,
  • Daniella De Souza e Silva,
  • Sérgio Paulo Campana-Filho,
  • Andreia Almeida,
  • Teófilo Vasconcelos,
  • Maria Palmira Daflon Gremião,
  • Beatriz Stringhetti Ferreira Cury and
  • Bruno Sarmento

8 January 2018

This work addresses the establishment and characterization of gellan gum:pectin (GG:P) biodegradable mucoadhesive beads intended for the colon-targeted delivery of resveratrol (RES). The impact of the polymer carrier system on the cytotoxicity and pe...

  • Article
  • Open Access
5 Citations
2,396 Views
13 Pages

23 September 2022

Improving milling and baking properties is important during wheat breeding. To determine changes in milling and baking quality of hard winter wheat, 23 adapted cultivars released in the Great Plains between 1870 and 2013 were grown in triplicate in a...

  • Article
  • Open Access
21 Citations
3,674 Views
18 Pages

Canopy Gaps Control Litter Decomposition and Nutrient Release in Subtropical Forests

  • Jiajia Chen,
  • Jing Zhu,
  • Ziwei Wang,
  • Cong Xing,
  • Bo Chen,
  • Xuelin Wang,
  • Chensi Wei,
  • Jinfu Liu,
  • Zhongsheng He and
  • Daowei Xu

24 March 2023

The formation of a canopy gap results in changes to the microenvironment which, in turn, affect litter decomposition and nutrient release. However, the mechanisms underlying these effects in differently sized gaps and non-gaps remain poorly understoo...

  • Article
  • Open Access
4 Citations
5,993 Views
16 Pages

30 July 2018

Results from numerical simulations of the mixing of two puffs of scalars released in a turbulent flow channel are used to introduce a measure of mixing quality, and to investigate the effectiveness of turbulent mixing as a function of the location of...

  • Article
  • Open Access
4 Citations
2,773 Views
15 Pages

Stationary Mach Configurations with Pulsed Energy Release on the Normal Shock

  • Mikhail V. Chernyshov,
  • Anna S. Kapralova,
  • Stanislav A. Matveev and
  • Karina E. Savelova

5 December 2021

We obtained a theoretical analysis of stationary Mach configurations of shock waves with a pulsed energy release at the main (normal) shock and a corresponding change in gas thermodynamic properties. As formation of the stationary Mach configuration...

  • Article
  • Open Access
545 Views
18 Pages

30 July 2025

Aiming at the multifunctional requirements of the limited space in high-end vehicle side-door latches, a double single-loop RRUPRR mechanism driven by a single motor for both electric releasing and cinching is proposed based on the POC set. The kinem...

  • Article
  • Open Access
6 Citations
5,381 Views
14 Pages

Preparation of Co-Processed Excipients for Controlled-Release of Drugs Assembled with Solid Lipid Nanoparticles and Direct Compression Materials

  • Luis Eduardo Serrano-Mora,
  • María L. Zambrano-Zaragoza,
  • Néstor Mendoza-Muñoz,
  • Gerardo Leyva-Gómez,
  • Zaida Urbán-Morlán and
  • David Quintanar-Guerrero

The purpose of the study was to develop a novel, directly compressible, co-processed excipient capable of providing a controlled-release drug system for the pharmaceutical industry. A co-processed powder was formed by adsorption of solid lipid nanopa...

  • Article
  • Open Access
20 Citations
4,099 Views
19 Pages

Physical and Functional Characterization of PLGA Nanoparticles Containing the Antimicrobial Peptide SAAP-148

  • Muhanad Ali,
  • Miriam E. van Gent,
  • Amy M. de Waal,
  • Bjorn R. van Doodewaerd,
  • Erik Bos,
  • Roman I. Koning,
  • Robert A. Cordfunke,
  • Jan Wouter Drijfhout and
  • Peter H. Nibbering

2 February 2023

Synthetic antimicrobial and antibiofilm peptide (SAAP-148) commits significant antimicrobial activities against antimicrobial resistant (AMR) planktonic bacteria and biofilms. However, SAAP-148 is limited by its low selectivity index, i.e., ratio bet...

  • Article
  • Open Access
69 Citations
10,601 Views
15 Pages

20 August 2014

New peptides with potential antimicrobial activity, encrypted in milk protein sequences, were searched for with the use of bioinformatic tools. The major milk proteins were hydrolyzed in silico by 28 enzymes. The obtained peptides were characterized...

  • Article
  • Open Access
10 Citations
2,785 Views
19 Pages

23 May 2022

This paper studied the fracability of tight sandstone reservoirs by means of incorporating geomechanics properties and surrounding in situ stresses into a new model. The new fracability evaluation model consists of variables such as brittleness index...

  • Article
  • Open Access
3 Citations
2,417 Views
23 Pages

Design of Experiments-Based Fire Performance Optimization of Epoxy and Carbon-Fiber-Reinforced Epoxy Polymer Composites

  • Christoph M. Pöhler,
  • Marwa Hamza,
  • Torsten Kolb,
  • Erik V. Bachtiar,
  • Libo Yan and
  • Bohumil Kasal

16 October 2023

The fire performance of epoxy and carbon-fiber-reinforced polymer (CFRP) composites with and without fire retardants (FR) (i.e., ammonium polyphosphate (APP), aluminum trihydroxide (ATH), melamine (MEL), expandable graphite (EG)) was investigated. A...

  • Article
  • Open Access
3 Citations
1,829 Views
19 Pages

10 November 2022

The total quota control and reserve of rare earths are important means for the sustainable development and utilization of rare-earth resources. Focusing on the government reserve of rare-earth products under stochastic demand, this paper analyses the...

  • Article
  • Open Access
21 Citations
3,713 Views
20 Pages

Thermal Insulating Rigid Polyurethane Foams with Bio-Polyol from Rapeseed Oil Modified by Phosphorus Additive and Reactive Flame Retardants

  • Marcin Zemła,
  • Aleksander Prociak,
  • Sławomir Michałowski,
  • Ugis Cabulis,
  • Mikelis Kirpluks and
  • Kirils Simakovs

16 October 2022

In this article, rigid polyurethane foams obtained with the addition of a bio-polyol from rapeseed oil, were modified with the dimethyl propane phosphonate as additive flame retardant and two reactive flame retardants diethyl (hydroxymethyl)phosphona...

  • Article
  • Open Access
16 Citations
2,794 Views
14 Pages

8 August 2023

Smart and intelligent xanthan gum/pluronic F-127 hydrogels were fabricated for the controlled delivery of atomoxetine HCl. Different parameters such as DSC, TGA, FTIR, XRD, SEM, drug loading, porosity, swelling index, drug release, and kinetics model...

  • Article
  • Open Access
20 Citations
5,013 Views
19 Pages

19 May 2022

The development of an effective gel capable of treating eczema remains a challenge in medicine. Because of its greater retention in the affected area, good absorption of wound exudates, and induction of cell growth, nanogel is widely investigated as...

  • Article
  • Open Access
5 Citations
1,806 Views
16 Pages

Dual Loading of Trans-Cinnamaldehyde and Either Paclitaxel or Curcumin in Chitosan Nanoparticles: Physicochemical Characterization and Biological Evaluation Against MDCK and HeLa Cells

  • Cynthia L. Barrera-Martínez,
  • Héctor I. Meléndez-Ortiz,
  • Felipe Padilla-Vaca,
  • Leonard I. Atanase,
  • René D. Peralta-Rodríguez and
  • Ioannis Liakos

31 October 2024

Biopolymer chitosan sub-micron particles (CSMPs) were prepared by the ionic gelation technique crosslinked with sodium tripolyphosphate co-loaded with trans-cinnamaldehyde (TCIN), and either curcumin (CUR) or paclitaxel (PTX). The size of the spheric...

  • Article
  • Open Access
22 Citations
2,687 Views
18 Pages

Development of Press-Coated, Floating-Pulsatile Drug Delivery of Lisinopril

  • Swati C. JAGDALE,
  • Vishnu M. SURYAWANSHI,
  • Sudhir V. PANDYA,
  • Bhanudas S. KUCHEKAR and
  • Aniruddha R. CHABUKSWAR

14 April 2014

Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor, primarily used for the treatment of hypertension, congestive heart failure, and heart attack. It belongs to BCS class III having a half-life of 12 hrs and 25% bioavailability. The purpos...

  • Article
  • Open Access
4 Citations
1,974 Views
19 Pages

Gel Cleaning in Heritage: Comparison of the Water Release among Gels and Traditional Pads

  • Antonio Sansonetti,
  • Cristiano Riminesi,
  • Sónia Mironiouk,
  • Noemi Proietti,
  • Valeria Di Tullio,
  • Roberto Nisticò,
  • Barbara Sacchi and
  • Carmen Canevali

2 November 2024

Water release is a crucial aspect when considering cleaning effects on water-sensitive materials. In conservation practice, a water-based cleaning method which limits water release is very often needed. Unfortunately, this is not accompanied by an ap...

  • Article
  • Open Access
23 Citations
7,119 Views
13 Pages

Silymarin-loaded mucoadhesive microbeads of Chitosan-MMT were developed using the ionotropic gelation technique. Characterization of the microbeads was performed by DSC, XRD, SEM, and FTIR techniques. In vitro mucoadhesion and drug release studies; g...

  • Article
  • Open Access
2 Citations
1,934 Views
17 Pages

22 November 2023

The article aims to analyze the fluid dynamics and combustion characteristics of a non-premixed flame burning a fuel mixture derived from ammonia partial decomposition injected in an air crossflow. Nominal pressure (5 bar) and inlet air temperature (...

  • Article
  • Open Access
12 Citations
4,419 Views
11 Pages

Spatial Distribution and Long-Term Persistence of Wolbachia-Infected Aedes aegypti in the Mentari Court, Malaysia

  • Yoon Ling Cheong,
  • Wasi A. Nazni,
  • Han Lim Lee,
  • Ahmad NoorAfizah,
  • Ibrahim C. MohdKhairuddin,
  • Ghazali M. R. Kamarul,
  • Nasir M. N. Nizam,
  • Mohd A. K. Arif,
  • Zabari M. NurZatilAqmar and
  • Saidin M. Irwan
  • + 10 authors

11 April 2023

Dengue is endemic in Malaysia, and vector control strategies are vital to reduce dengue transmission. The Wolbachia strain wAlbB carried by both sexes of Ae. aegypti was released in Mentari Court, a high-rise residential site, in October 2017 and sto...

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