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  • Article
  • Open Access
25 Citations
14,191 Views
16 Pages

Polydopamine-Supported Lipid Bilayers

  • Souryvanh Nirasay,
  • Antonella Badia,
  • Grégoire Leclair,
  • Jerome P. Claverie and
  • Isabelle Marcotte

4 December 2012

We report the formation of lipid membranes supported by a soft polymeric cushion of polydopamine. First, 20 nm thick polydopamine films were formed on mica substrates. Atomic force microscopy imaging indicated that these films were also soft with a s...

  • Article
  • Open Access
46 Citations
8,504 Views
11 Pages

Polydopamine Antioxidant Hydrogels for Wound Healing Applications

  • Naphtali A. O’Connor,
  • Abdulhaq Syed,
  • Madeline Wong,
  • Josiah Hicks,
  • Greisly Nunez,
  • Andrei Jitianu,
  • Zach Siler and
  • Marnie Peterson

31 October 2020

Antioxidants are known to improve the wound healing process and are researched as a therapeutic strategy to treat chronic wounds. Dopamine is a known neurotransmitter with antioxidant properties that can be polymerized to form polydopamine (PDA). Her...

  • Review
  • Open Access
97 Citations
9,165 Views
22 Pages

From Bioinspired Glue to Medicine: Polydopamine as a Biomedical Material

  • Daniel Hauser,
  • Dedy Septiadi,
  • Joel Turner,
  • Alke Petri-Fink and
  • Barbara Rothen-Rutishauser

7 April 2020

Biological structures have emerged through millennia of evolution, and nature has fine-tuned the material properties in order to optimise the structure–function relationship. Following this paradigm, polydopamine (PDA), which was found to be cr...

  • Article
  • Open Access
8 Citations
2,245 Views
10 Pages

11 November 2023

Polydopamine-based materials have been widely investigated for incorporation in energetic nanocomposites due to their outstanding adherence. However, these materials are often prepared in alkaline environments, which negatively affects Al nanoparticl...

  • Article
  • Open Access
28 Citations
6,406 Views
21 Pages

Polydopamine/Transferrin Hybrid Nanoparticles for Targeted Cell-Killing

  • Daniel Hauser,
  • Manuela Estermann,
  • Ana Milosevic,
  • Lukas Steinmetz,
  • Dimitri Vanhecke,
  • Dedy Septiadi,
  • Barbara Drasler,
  • Alke Petri-Fink,
  • Vincent Ball and
  • Barbara Rothen-Rutishauser

17 December 2018

Polydopamine can form biocompatible particles that convert light into heat. Recently, a protocol has been optimized to synthesize polydopamine/protein hybrid nanoparticles that retain the biological function of proteins, and combine it with the stimu...

  • Review
  • Open Access
20 Citations
11,874 Views
32 Pages

Incorporating polydopamine has become a viable method for membrane modification due to its universality and versatility. Fillers in their different categories have been confirmed as effective elements to improve the properties of membranes such as hy...

  • Feature Paper
  • Article
  • Open Access
46 Citations
5,834 Views
15 Pages

Size Matters in the Cytotoxicity of Polydopamine Nanoparticles in Different Types of Tumors

  • Celia Nieto,
  • Milena A. Vega,
  • Jesús Enrique,
  • Gema Marcelo and
  • Eva M. Martín del Valle

29 October 2019

Polydopamine has acquired great relevance in the field of nanomedicine due to its physicochemical properties. Previously, it has been reported that nanoparticles synthetized from this polymer are able to decrease the viability of breast and colon tum...

  • Article
  • Open Access
6 Citations
4,327 Views
14 Pages

20 February 2024

Polypyrrole films are commonly prepared as conductive electrode surfaces for a variety of applications. Recently, there has been increasing interest in improving the adhesive properties and biocompatibility of polypyrrole electrodes via the incorpora...

  • Review
  • Open Access
67 Citations
9,131 Views
17 Pages

Polydopamine-Coated Magnetic Iron Oxide Nanoparticles: From Design to Applications

  • Giulia Siciliano,
  • Anna Grazia Monteduro,
  • Antonio Turco,
  • Elisabetta Primiceri,
  • Silvia Rizzato,
  • Nicoletta Depalo,
  • Maria Lucia Curri and
  • Giuseppe Maruccio

30 March 2022

Magnetic iron oxide nanoparticles have been extensively investigated due to their applications in various fields such as biomedicine, sensing, and environmental remediation. However, they need to be coated with a suitable material in order to make th...

  • Article
  • Open Access
18 Citations
4,880 Views
15 Pages

Benefits of Polydopamine as Particle/Matrix Interface in Polylactide/PD-BaSO4 Scaffolds

  • Naroa Sadaba,
  • Aitor Larrañaga,
  • Gemma Orpella-Aceret,
  • Ana F. Bettencourt,
  • Victor Martin,
  • Manus Biggs,
  • Isabel A. C. Ribeiro,
  • Jone M. Ugartemendia,
  • Jose-Ramon Sarasua and
  • Ester Zuza

This work reports the versatility of polydopamine (PD) when applied as a particle coating in a composite of polylactide (PLA). Polydopamine was observed to increase the particle–matrix interface strength and facilitate the adsorption of drugs t...

  • Review
  • Open Access
75 Citations
7,502 Views
18 Pages

Polydopamine (PDA), as a mussel-inspired material, exhibits numerous favorable performance characteristics, such as a simple preparation process, prominent photothermal transfer efficiency, excellent biocompatibility, outstanding drug binding ability...

  • Feature Paper
  • Article
  • Open Access
19 Citations
3,691 Views
19 Pages

Polydopamine Linking Substrate for AMPs: Characterisation and Stability on Ti6Al4V

  • Zuzanna Trzcińska,
  • Marc Bruggeman,
  • Hanieh Ijakipour,
  • Nikolas J. Hodges,
  • James Bowen and
  • Artemis Stamboulis

22 August 2020

Infections are common complications in joint replacement surgeries. Eradicated infections can lead to implant failure. In this paper, analogues of the peptide KR-12 derived from the human cathelicidin LL-37 were designed, synthesised, and characteris...

  • Article
  • Open Access
22 Citations
5,755 Views
12 Pages

Micro-Structured Polydopamine Films via Pulsed Electrochemical Deposition

  • Jing Lin,
  • Sven Daboss,
  • Dominik Blaimer and
  • Christine Kranz

11 February 2019

Polydopamine (PDA) films are interesting as smart functional materials, and their controlled structured formation plays a significant role in a wide range of applications ranging from cell adhesion to sensing and catalysis. A pulsed deposition techni...

  • Conference Report
  • Open Access
1 Citations
4,715 Views
9 Pages

1st Symposium on Polydopamine and NanoTech Poland 2018: Conference Report

  • Radosław Mrówczyński,
  • Marco D’Ischia,
  • Haeshin Lee and
  • Stefan Jurga

The NanoTech Poland is an annual international conference with a strong scientific agenda focused on nanotechnology in energy, environment, and biomedicine. The Nanotech Poland 2018 was held at the NanoBioMedical Centre and Department of Physics at A...

  • Article
  • Open Access
3 Citations
2,575 Views
13 Pages

Antibacterial Silver Nanoparticle Containing Polydopamine Hydrogels That Enhance Re-Epithelization

  • Naphtali A. O’Connor,
  • Abdulhaq Syed,
  • Ertan Kastrat and
  • Hai-Ping Cheng

24 May 2024

A polydopamine polyelectrolyte hydrogel was developed by ionic crosslinking dextran sulfate with a copolymer of polyethyleneimine and polydopamine. Gelation was promoted by the slow hydrolysis of glucono-δ-lactone. Within this hydrogel, silver...

  • Article
  • Open Access
12 Citations
7,396 Views
12 Pages

25 May 2016

Root caries prevention has been a challenge for clinicians due to its special anatomical location, which favors the accumulation of dental plaque. Researchers are looking for anti-biofouling material to inhibit bacterial growth on exposed root surfac...

  • Article
  • Open Access
10 Citations
3,208 Views
15 Pages

14 November 2021

The paper presents the results of copper electroless metallization of cellulose paper with the use of a polydopamine coating and silver catalyst. The polydopamine coating was deposited via a simple dip method using a dopamine hydrochloride solution i...

  • Article
  • Open Access
55 Citations
11,699 Views
15 Pages

Polydopamine Particle as a Particulate Emulsifier

  • Nobuaki Nishizawa,
  • Ayaka Kawamura,
  • Michinari Kohri,
  • Yoshinobu Nakamura and
  • Syuji Fujii

26 February 2016

“Pickering-type” emulsions were prepared using polydopamine (PDA) particles as a particulate emulsifier and n-dodecane, methyl myristate, toluene or dichloromethane as an oil phase. All the emulsions prepared were oil-in-water type and an increase of...

  • Article
  • Open Access
4 Citations
2,650 Views
13 Pages

Assessment of Polydopamine to Reduce Streptococcus mutans Adhesion to a Dental Polymer

  • Santiago Arango-Santander,
  • Carlos Martinez,
  • Claudia Bedoya-Correa,
  • Juliana Sanchez-Garzon and
  • John Franco

8 October 2023

Bacterial adhesion to the surface of materials is the first step in biofilm formation, which will lead to conditions that may compromise the health status of patients. Recently, polydopamine (PDA) has been proposed as an antibacterial material. There...

  • Article
  • Open Access
9 Citations
3,744 Views
14 Pages

18 March 2022

Although aramid fiber has the advantage of excellent chemical and mechanical properties, the performance of the composites may be reduced due to the low interfacial adhesion between the fabric and the matrix. The surface of the aramid fiber was modif...

  • Review
  • Open Access
28 Citations
7,342 Views
47 Pages

7 August 2024

This manuscript explores the multifaceted applications of polydopamine (PDA) across various scientific and industrial domains. It covers the chemical aspects of PDA and its potential in bone tissue engineering, implant enhancements, cancer treatment,...

  • Review
  • Open Access
10 Citations
4,186 Views
19 Pages

30 April 2022

Fluorescence nanoparticles have gained much attention due to their unique properties in the sensing and imaging fields. Among the very successful candidates are fluorescent polydopamine (FPDA) nanoparticles, attributed to their simplicity in tracing...

  • Article
  • Open Access
5 Citations
2,875 Views
12 Pages

Uptake of Magnetite Nanoparticles on Polydopamine Films Deposited on Gold Surfaces: A Study by AFM and XPS

  • Andrea Atrei,
  • Shalva Chokheli,
  • Maddalena Corsini,
  • Tóth József and
  • Giuseppe Di Florio

24 October 2024

Polydopamine has the capacity to adhere to a large variety of materials and this property offers the possibility to bind nanoparticles to solid surfaces. In this work, magnetite nanoparticles were deposited on gold substrates coated with polydopamine...

  • Review
  • Open Access
13 Citations
4,359 Views
23 Pages

Polydopamine-Based Nanoprobes Application in Optical Biosensing

  • Arianna Menichetti,
  • Alexandra Mavridi-Printezi,
  • Dario Mordini and
  • Marco Montalti

27 October 2023

Polydopamine (PDA), the synthetic counterpart of melanin, is a widely investigated bio-inspired material for its chemical and photophysical properties, and in the last few years, bio-application of PDA and PDA-based materials have had a dramatic incr...

  • Article
  • Open Access
11 Citations
4,459 Views
16 Pages

18 March 2023

The development of green, biomedical hydrogels using natural polymers is of great significance. From this viewpoint, guar gum (GG) has been widely used for hydrogel preparation; however, its mechanical strength and adhesion often cannot satisfy the b...

  • Review
  • Open Access
26 Citations
5,200 Views
20 Pages

Frontiers in Preparations and Promising Applications of Mesoporous Polydopamine for Cancer Diagnosis and Treatment

  • Hualin Ma,
  • Jingwen Peng,
  • Jianing Zhang,
  • Li Pan,
  • Jiayi Ouyang,
  • Zimu Li,
  • Baochun Guo,
  • Zhen Wang,
  • Ying Xu and
  • Xiaowei Zeng
  • + 1 author

Polydopamine (PDA) is a natural melanin derived from marine mussels that has good biocompatibility, biodegradability, and photothermal conversion ability. As a new coating material, it offers a novel way to modify the surface of various substances. T...

  • Article
  • Open Access
15 Citations
7,218 Views
17 Pages

2 April 2023

In this study, according to the acquired polydopamine deposition rates, polydopamine films with equal thickness were prepared under different conditions on SiO2 substrates. Subsequently, we investigated the influence of dopamine solution pH and conce...

  • Article
  • Open Access
10 Citations
3,689 Views
11 Pages

Using γ-Ray Polymerization-Induced Assemblies to Synthesize Polydopamine Nanocapsules

  • Wenwen Jiang,
  • Xinyue Zhang,
  • Yafei Luan,
  • Rensheng Wang,
  • Hanzhou Liu,
  • Dan Li and
  • Liang Hu

25 October 2019

This work reports a simple and robust strategy for synthesis of polydopamine nanocapsules (PDA NCs). First, polymer assemblies were synthesized by a γ-ray-induced liquid–liquid (H2O–acrylate) interface polymerization strategy, in th...

  • Communication
  • Open Access
1 Citations
6,182 Views
10 Pages

Microwave-Induced Chemotoxicity of Polydopamine-Coated Magnetic Nanocubes

  • Khachatur Julfakyan,
  • Yevhen Fatieiev,
  • Shahad Alsaiari,
  • Lin Deng,
  • Alaa Ezzeddine,
  • Dingyuan Zhang,
  • Vincent M. Rotello and
  • Niveen M. Khashab

6 August 2015

Polydopamine-coated FeCo nanocubes (PDFCs) were successfully synthesized and tested under microwave irradiation of 2.45 GHz frequency and 0.86 W/cm2 power. These particles were found to be non-toxic in the absence of irradiation, but gained significa...

  • Article
  • Open Access
23 Citations
4,972 Views
9 Pages

A Gold Nanoclusters Film Supported on Polydopamine for Fluorescent Sensing of Free Bilirubin

  • Zhou Li,
  • Wenxiang Xiao,
  • Rongen Huang,
  • Yajing Shi,
  • Cheng Fang and
  • Zhencheng Chen

10 April 2019

Serum bilirubin is an important biomarker for the diagnosis of various types of liver diseases and blood disorders. A polydopamine/gold nanoclusters composite film was fabricated for the fluorescent sensing of free bilirubin. Bovine serum albumin (BS...

  • Article
  • Open Access
11 Citations
3,684 Views
16 Pages

26 October 2020

Astrocytes, also known as astroglia, are important cells for the structural support of neurons as well as for biochemical balance in the central nervous system (CNS). In this study, the polymerization of dopamine (DA) to polydopamine (PDA) and its ef...

  • Article
  • Open Access
5 Citations
6,788 Views
16 Pages

In Vitro Findings of Titanium Functionalized with Estradiol via Polydopamine Adlayer

  • Chris Steffi,
  • Zhilong Shi,
  • Chee Hoe Kong and
  • Wilson Wang

To improve orthopedic implant fixation and reduce post-operative complications, osteogenic molecules are delivered locally by immobilizing them on the surface of implants, which will modulate the biology of cell attachment and differentiation on the...

  • Article
  • Open Access
130 Citations
8,246 Views
13 Pages

30 April 2020

The mussel inspired polydopamine has acquired great relevance in the field of nanomedicines, owing to its incredible physicochemical properties. Polydopamine nanoparticles (PDA NPs) due to their low cytotoxicity, high biocompatibility and ready biode...

  • Review
  • Open Access
19 Citations
8,048 Views
16 Pages

Polydopamine (PDA) is related to eumelanins in its composition and structure. These pigments allow the design, inspired by natural materials, of composite nanoparticles and films for applications in the field of energy conversion and the design of bi...

  • Article
  • Open Access
6 Citations
2,357 Views
15 Pages

23 August 2023

In this study, we prepared composites made from polyvinyl alcohol (PVA), sodium alginate (SA), curcumin (Cur), and polydopamine (PD). The film-forming properties of the composites were researched for potential wound-healing applications. The structur...

  • Article
  • Open Access
11 Citations
3,734 Views
14 Pages

Selective Passivation of Three-Dimensional Carbon Microelectrodes by Polydopamine Electrodeposition and Local Laser Ablation

  • Babak Rezaei,
  • Saloua Saghir,
  • Jesper Yue Pan,
  • Rasmus Schmidt Davidsen and
  • Stephan Sylvest Keller

26 February 2022

In this article, a novel approach for selective passivation of three-dimensional pyrolytic carbon microelectrodes via a facile electrochemical polymerization of a non-conductive polymer (polydopamine, PDA) onto the surface of carbon electrodes, follo...

  • Article
  • Open Access
12 Citations
3,538 Views
15 Pages

Polydopamine Copolymers for Stable Drug Nanoprecipitation

  • Danna Niezni,
  • Yuval Harris,
  • Hagit Sason,
  • Maytal Avrashami and
  • Yosi Shamay

17 October 2022

Polydopamine (PDA), a biomaterial inspired by marine mussels, has attracted interest in cancer nanomedicine due to its photothermal properties, nanoparticle coating, and pi-pi stacking-based drug encapsulation abilities. Despite numerous one-pot and...

  • Article
  • Open Access
41 Citations
7,005 Views
15 Pages

Two-Step Dopamine-to-Polydopamine Modification of Polyethersulfone Ultrafiltration Membrane for Enhancing Anti-Fouling and Ultraviolet Resistant Properties

  • Sri Mulyati,
  • Syawaliah Muchtar,
  • Nasrul Arahman,
  • Yanna Syamsuddin,
  • Normi Izati Mat Nawi,
  • Noorfidza Yub Harun,
  • Muhammad Roil Bilad,
  • Yuliar Firdaus,
  • Ryosuke Takagi and
  • Hideto Matsuyama

9 September 2020

Polydopamine has been widely used as an additive to enhance membrane fouling resistance. This study reports the effects of two-step dopamine-to-polydopamine modification on the permeation, antifouling, and potential anti-UV properties of polyethersul...

  • Article
  • Open Access
14 Citations
4,926 Views
10 Pages

Hairy Polydopamine Particles as Platforms for Photonic and Magnetic Materials

  • Michinari Kohri,
  • Kanako Uradokoro,
  • Yuri Nannichi,
  • Ayaka Kawamura,
  • Tatsuo Taniguchi and
  • Keiki Kishikawa

12 October 2018

By selecting the core materials and grafted-hair polymers, hairy particles with polymer brushes can create various types of functional materials. In recent years, polydopamine (PDA) particles that are obtained by polymerizing dopamine, which is an am...

  • Article
  • Open Access
1 Citations
659 Views
17 Pages

29 November 2025

Polycaprolactone (PCL) is a synthetic biodegradable polymer widely used in biomedical research due to its flexibility, safety for use in the body, and FDA approval for medical use. Nevertheless, its inherent hydrophobicity and restricted bioactivity...

  • Article
  • Open Access
3 Citations
2,082 Views
13 Pages

Bioinspired Fabrication of an Insensitive Ammonium Perchlorate Core–Shell Composite with Polydopamine Coating

  • Yafeng Huang,
  • Xuan Tian,
  • Jinfei Wang,
  • Kejun Zhong,
  • Yuan Chen,
  • Chenglong Li and
  • Pengxiang Jia

11 April 2024

In this research, an ammonium perchlorate/polydopamine (AP/PDA) core–shell composite was prepared in a non-aqueous solution to reduce the mechanical sensitivity of ammonium perchlorate (AP). The result showed that the AP/PDA core–shell co...

  • Article
  • Open Access
27 Citations
7,323 Views
15 Pages

23 May 2018

Polydopamine (PDA) displays many striking properties of naturally occurring melanin in optics, electricity, and biocompatibility. Another valuable feature of polydopamine lies in its chemical structure that incorporates many functional groups such as...

  • Review
  • Open Access
15 Citations
5,321 Views
19 Pages

Polydopamine-Based Material and Their Potential in Head and Neck Cancer Therapy—Current State of Knowledge

  • Marta Witkowska,
  • Ewelina Golusińska-Kardach,
  • Wojciech Golusiński and
  • Ewa Florek

Head and neck cancers (HNC) are among the most common cancers in the world. In terms of frequency of occurrence in the world, HNC ranks sixth. However, the problem of modern oncology is the low specificity of the therapies used, which is why most of...

  • Article
  • Open Access
10 Citations
3,627 Views
17 Pages

In clinical cancer research, photothermal therapy is one of the most effective ways to increase sensitivity to chemotherapy. Here, we present a simple and effective method for developing a nanotherapeutic agent for chemotherapy combined with photothe...

  • Article
  • Open Access
27 Citations
3,456 Views
9 Pages

19 January 2022

Breakdown strength is an important parameter for polymer dielectric, and introducing inorganic filler into the polymer matrix is an efficient method to improve the breakdown strength. In this work, graphitic carbon nitride nanosheets (CNNS) were ultr...

  • Feature Paper
  • Article
  • Open Access
15 Citations
5,165 Views
12 Pages

30 November 2021

Biomass-derived three-dimensional (3D) porous nanocarbons have attracted much attention due to their high surface area, permeability, electrical conductivity, and renewability, which are beneficial for various electronic applications, including energ...

  • Article
  • Open Access
22 Citations
7,745 Views
12 Pages

Immobilization of Thermostable Lipase QLM on Core-Shell Structured Polydopamine-Coated Fe3O4 Nanoparticles

  • Chenhui Wang,
  • Haobo Han,
  • Wei Jiang,
  • Xiaobo Ding,
  • Quanshun Li and
  • Yanbo Wang

6 February 2017

Here, core-shell structured polydopamine-coated Fe3O4 nanoparticles were constructed to immobilize thermostable lipase QLM from Alcaligenes sp. Systematical characterization indicated that lipase QLM was successfully immobilized on the surface of nan...

  • Review
  • Open Access
35 Citations
5,569 Views
19 Pages

Polydopamine Nanomaterials for Overcoming Current Challenges in Cancer Treatment

  • Shahinur Acter,
  • Michele Moreau,
  • Robert Ivkov,
  • Akila Viswanathan and
  • Wilfred Ngwa

17 May 2023

In efforts to overcome current challenges in cancer treatment, multifunctional nanoparticles are attracting growing interest, including nanoparticles made with polydopamine (PDA). PDA is a nature-inspired polymer with a dark brown color. It has excel...

  • Article
  • Open Access
11 Citations
5,227 Views
15 Pages

A Novel Bio-Adhesive Based on Chitosan-Polydopamine-Xanthan Gum for Glass, Cardboard and Textile Commodities

  • Jessica Costa,
  • Maria Camilla Baratto,
  • Daniele Spinelli,
  • Gemma Leone,
  • Agnese Magnani and
  • Rebecca Pogni

26 June 2024

The escalating environmental concerns associated with petroleum-based adhesives have spurred an urgent need for sustainable alternatives. Chitosan, a natural polysaccharide, is a promising candidate; however, its limited water resistance hinders broa...

  • Article
  • Open Access
103 Citations
8,918 Views
17 Pages

27 January 2021

High-degree functionalization of graphene oxide (GO) nanoparticles (NPs) using polydopamine (PDA) was conducted to produce polydopamine functionalized graphene oxide nanoparticles (GO-PDA NPs). Aiming to explore their potential use as nanofiller in m...

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