Next Article in Journal
Potential Effects of Phytoestrogen Genistein in Modulating Acute Methotrexate Chemotherapy-Induced Osteoclastogenesis and Bone Damage in Rats
Next Article in Special Issue
Characterization, Quantification, and Determination of the Toxicity of Iron Oxide Nanoparticles to the Bone Marrow Cells
Previous Article in Journal
Kynurenines and Multiple Sclerosis: The Dialogue between the Immune System and the Central Nervous System
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
IJMS
Volume 16
Issue 8
10.3390/ijms160818283
ijms-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Communication

Microwave-Induced Chemotoxicity of Polydopamine-Coated Magnetic Nanocubes

by
Khachatur Julfakyan
1,
Yevhen Fatieiev
1,
Shahad Alsaiari
1,
Lin Deng
1,
Alaa Ezzeddine
1,
Dingyuan Zhang
1,2,
Vincent M. Rotello
3 and
Niveen M. Khashab
1,*
1
Smart Hybrid Materials (SHMs) Laboratory, Advanced Membranes and Porous Materials Center, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia
2
Key Laboratory of Synthetic and Self-Assembly Chemistry for Organic Functional Molecules, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China
3
Department of Chemistry, University of Massachusetts Amherst, Amherst, MA 01003, USA
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2015, 16(8), 18283-18292; https://doi.org/10.3390/ijms160818283
Submission received: 29 June 2015 / Revised: 21 July 2015 / Accepted: 29 July 2015 / Published: 6 August 2015
(This article belongs to the Special Issue Developmental and Reproductive Toxicity of Iron Oxide Nanoparticles)
Browse Figures
Versions Notes

Abstract

Polydopamine-coated FeCo nanocubes (PDFCs) were successfully synthesized and tested under microwave irradiation of 2.45 GHz frequency and 0.86 W/cm2 power. These particles were found to be non-toxic in the absence of irradiation, but gained significant toxicity upon irradiation. Interestingly, no increase in relative heating rate was observed when the PDFCs were irradiated in solution, eliminating nanoparticle (NP)-induced thermal ablation as the source of toxicity. Based on these studies, we propose that microwave-induced redox processes generate the observed toxicity.
Keywords: FeCo nanocubes; polydopamine; microwave radiation; nanomedicine FeCo nanocubes; polydopamine; microwave radiation; nanomedicine
Graphical Abstract

Share and Cite

MDPI and ACS Style

Julfakyan, K.; Fatieiev, Y.; Alsaiari, S.; Deng, L.; Ezzeddine, A.; Zhang, D.; Rotello, V.M.; Khashab, N.M. Microwave-Induced Chemotoxicity of Polydopamine-Coated Magnetic Nanocubes. Int. J. Mol. Sci. 2015, 16, 18283-18292. https://doi.org/10.3390/ijms160818283

AMA Style

Julfakyan K, Fatieiev Y, Alsaiari S, Deng L, Ezzeddine A, Zhang D, Rotello VM, Khashab NM. Microwave-Induced Chemotoxicity of Polydopamine-Coated Magnetic Nanocubes. International Journal of Molecular Sciences. 2015; 16(8):18283-18292. https://doi.org/10.3390/ijms160818283

Chicago/Turabian Style

Julfakyan, Khachatur, Yevhen Fatieiev, Shahad Alsaiari, Lin Deng, Alaa Ezzeddine, Dingyuan Zhang, Vincent M. Rotello, and Niveen M. Khashab. 2015. "Microwave-Induced Chemotoxicity of Polydopamine-Coated Magnetic Nanocubes" International Journal of Molecular Sciences 16, no. 8: 18283-18292. https://doi.org/10.3390/ijms160818283

APA Style

Julfakyan, K., Fatieiev, Y., Alsaiari, S., Deng, L., Ezzeddine, A., Zhang, D., Rotello, V. M., & Khashab, N. M. (2015). Microwave-Induced Chemotoxicity of Polydopamine-Coated Magnetic Nanocubes. International Journal of Molecular Sciences, 16(8), 18283-18292. https://doi.org/10.3390/ijms160818283

Article Metrics

Back to TopTop