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52 Results Found

  • Review
  • Open Access
24 Citations
6,348 Views
18 Pages

Interaction Mechanisms and Application of Ozone Micro/Nanobubbles and Nanoparticles: A Review and Perspective

  • Wei Xiao,
  • He Zhang,
  • Xiaohuan Wang,
  • Biao Wang,
  • Tao Long,
  • Sha Deng and
  • Wei Yang

7 June 2022

Ozone micro/nanobubbles with catalytic processes are widely used in the treatment of refractory organic wastewater. Micro/nanobubble technology overcomes the limitations of ozone mass transfer and ozone utilization in the application of ozone oxidati...

  • Article
  • Open Access
2 Citations
1,377 Views
24 Pages

10 June 2025

The co-occurring relationships between ilmenite and gangue minerals in ilmenite deposits, as well as fine mineral embedding particle sizes, are complex. During the beneficiation process, grinding ilmenite finely is necessary to achieve sufficient ind...

  • Review
  • Open Access
1 Citations
2,124 Views
23 Pages

Properties of CO2 Micro-Nanobubbles and Their Significant Applications in Sustainable Development

  • Zeyun Zheng,
  • Xingya Wang,
  • Tao Tang,
  • Jun Hu,
  • Xingfei Zhou and
  • Lijuan Zhang

17 August 2025

As an important part of global carbon neutrality strategies, carbon dioxide (CO2) capture, utilization, and storage technologies have emerged as critical solutions for reducing carbon emissions. However, conventional CO2 applications, including food...

  • Article
  • Open Access
3 Citations
2,768 Views
18 Pages

Prediction Model and Influencing Factors of CO2 Micro/Nanobubble Release Based on ARIMA-BPNN

  • Bingbing Wang,
  • Xiangjie Lu,
  • Yanzhao Ren,
  • Sha Tao and
  • Wanlin Gao

The quantitative prediction of CO2 concentration in the growth environment of crops is a key technology for CO2 enrichment applications. The characteristics of micro/nanobubbles in water make CO2 micro/nanobubble water potentially useful for enrichin...

  • Review
  • Open Access
1 Citations
824 Views
12 Pages

Ultrasound-responsive micro/nanobubbles (MNBs) are promising tools for targeted cancer therapy due to their controllable acoustic activation and real-time imaging. Despite extensive research, the quantitative relationship between bubble structure, ac...

  • Article
  • Open Access
15 Citations
4,773 Views
15 Pages

Preparation and Properties of CO2 Micro-Nanobubble Water Based on Response Surface Methodology

  • Bingbing Wang,
  • Xiangjie Lu,
  • Sha Tao,
  • Yanzhao Ren,
  • Wanlin Gao,
  • Xinliang Liu and
  • Bangjie Yang

8 December 2021

Carbon dioxide (CO2) enrichment in an agricultural environment has been shown to enhance the efficiency of crop photosynthesis, increasing crop yield and product quality. There is a problem of the excessive use of CO2 gas when the CO2 is enriched for...

  • Article
  • Open Access
6 Citations
2,687 Views
18 Pages

Effect of Micro-Nanobubbles on Arsenic Removal by Trichoderma atroviride for Bioscorodite Generation

  • Asunción Guadalupe Morales-Mendoza,
  • Ana Karen Ivanna Flores-Trujillo,
  • Jesús Adriana Ramírez-Castillo,
  • Salvador Gallardo-Hernández and
  • Refugio Rodríguez-Vázquez

17 August 2023

The global environmental issue of arsenic (As) contamination in drinking water is a significant problem that requires attention. Therefore, the aim of this research was to address the application of a sustainable methodology for arsenic removal throu...

  • Feature Paper
  • Review
  • Open Access
27 Citations
7,772 Views
31 Pages

Generation Mechanism of Hydroxyl Free Radicals in Micro–Nanobubbles Water and Its Prospect in Drinking Water

  • Tianzhi Wang,
  • Ci Yang,
  • Peizhe Sun,
  • Mingna Wang,
  • Fawei Lin,
  • Manuel Fiallos and
  • Soon-Thiam Khu

28 March 2024

Micro–nanobubbles (MNBs) can generate ·OH in situ, which provides a new idea for the safe and efficient removal of pollutants in water supply systems. However, due to the difficulty in obtaining stable MNBs, the generation efficiency of...

  • Article
  • Open Access
3 Citations
6,468 Views
14 Pages

A Desktop Assessment of Ozone Micro-Nanobubble Technology for Algae and PFAS Removal from Surface Water Bodies Using Open-Source Water Quality Data

  • Soheil Aber,
  • Rachelle Aguada,
  • Randimal Marasinghe,
  • Christopher W. K. Chow,
  • Raufdeen Rameezdeen and
  • Ke Xing

12 January 2024

Ozone is an excellent oxidant and helps in breaking down both organic and inorganic compounds; this effect is further enhanced when it decomposes into hydroxyl radicals. Several studies confirm the good performance of ozonation and micro-nanobubble t...

  • Article
  • Open Access
8 Citations
3,844 Views
13 Pages

Numerical Simulation of Gas–Liquid Two-Phase Flow CFD–PBM Model in a Micro–Nanobubble Generator

  • Weiguang Xu,
  • Wenjuan Li,
  • Jianwei Wang,
  • Yongsheng Song,
  • Biao Wu,
  • Jiankang Wen,
  • Kaiguo Li and
  • Bin Li

8 October 2022

A micro–nanobubble generator is the most critical component of micro–nano flotation equipment. Understanding the bubble generation characteristics in the generator plays a vital role in optimizing the performance of the device and improvi...

  • Review
  • Open Access
33 Citations
5,016 Views
21 Pages

Ultrasound with low frequency (20–100 kHz) assisted drug delivery has been widely investigated as a non-invasive method to enhance the permeability and retention effect of drugs. The functional micro/nanobubble loaded with drugs could provide a...

  • Article
  • Open Access
9 Citations
3,359 Views
19 Pages

Advanced Simulation of Quartz Flotation Using Micro-Nanobubbles by Hybrid Serving of Historical Data (HD) and Deep Learning (DL) Methods

  • Sabereh Nazari,
  • Alireza Gholami,
  • Hamid Khoshdast,
  • Jinlong Li,
  • Yaqun He and
  • Ahmad Hassanzadeh

16 January 2023

The present study investigates the optimization and advanced simulation of the flotation process of coarse particles (–425 + 106) using micro-nanobubbles (MNBs). For this purpose, flotation experiments in the presence and absence of MNBs were perform...

  • Article
  • Open Access
29 Citations
3,912 Views
15 Pages

An Assessment of the Role of Combined Bulk Micro- and Nano-Bubbles in Quartz Flotation

  • Shaoqi Zhou,
  • Yang Li,
  • Sabereh Nazari,
  • Xiangning Bu,
  • Ahmad Hassanzadeh,
  • Chao Ni,
  • Yaqun He and
  • Guangyuan Xie

27 July 2022

Bulk micro-nano-bubbles (BMNBs) have been proven to be effective at improving the flotation recovery and kinetics of fine-grained minerals. However, there is currently no research reported on the correlation between the properties of BMNBs and flotat...

  • Review
  • Open Access
5 Citations
5,603 Views
18 Pages

Clinical Applications of Micro/Nanobubble Technology in Neurological Diseases

  • Parth B. Patel,
  • Sun Latt,
  • Karan Ravi and
  • Mehdi Razavi

Nanomedicine, leveraging the unique properties of nanoparticles, has revolutionized the diagnosis and treatment of neurological diseases. Among various nanotechnological advancements, ultrasound-mediated drug delivery using micro- and nanobubbles off...

  • Review
  • Open Access
70 Citations
12,377 Views
19 Pages

Oxygen-Carrying Micro/Nanobubbles: Composition, Synthesis Techniques and Potential Prospects in Photo-Triggered Theranostics

  • Muhammad Saad Khan,
  • Jangsun Hwang,
  • Kyungwoo Lee,
  • Yonghyun Choi,
  • Kyobum Kim,
  • Hyung-Jun Koo,
  • Jong Wook Hong and
  • Jonghoon Choi

31 August 2018

Microbubbles and nanobubbles (MNBs) can be prepared using various shells, such as phospholipids, polymers, proteins, and surfactants. MNBs contain gas cores due to which they are echogenic and can be used as contrast agents for ultrasonic and photoac...

  • Review
  • Open Access
35 Citations
4,163 Views
12 Pages

Stability of Engineered Micro or Nanobubbles for Biomedical Applications

  • Beomjin Park,
  • Semi Yoon,
  • Yonghyun Choi,
  • Jaehee Jang,
  • Soomin Park and
  • Jonghoon Choi

A micro/nanobubble (MNB) refers to a bubble structure sized in a micrometer or nanometer scale, in which the core is separated from the external environment and is normally made of gas. Recently, it has been confirmed that MNBs can be widely used in...

  • Article
  • Open Access
16 Citations
4,259 Views
13 Pages

29 February 2020

In this study, the effect of hydrodynamic cavitation (HC) on the conditioning stage (HCCS), separation stage (HCSS), and whole stage (HCWS) of coal flotation was investigated by flotation tests, laser granulometry, and contact angle measurements. The...

  • Article
  • Open Access
13 Citations
4,571 Views
11 Pages

2 August 2022

Micro-nanobubbles (MNBs) technology has emerged as an effective means of sewage treatment, while the molecular mechanism for its pollutant degradation is still unknown. In this paper, the reactive molecular dynamics simulation technique is used to st...

  • Article
  • Open Access
8 Citations
4,103 Views
18 Pages

13 March 2024

The use of integrated plasma-activated water (PAW) with micro/nanobubbles (MNBs), ultraviolet (UV) photolysis, and ultrasonication (US) for the synergistic efficiency of Escherichia coli inactivation in chicken meat was investigated. A 2k factorial d...

  • Article
  • Open Access
90 Citations
9,913 Views
10 Pages

Effect of NaCl on the Lifetime of Micro- and Nanobubbles

  • Tsutomu Uchida,
  • Shu Liu,
  • Masatoshi Enari,
  • Seiichi Oshita,
  • Kenji Yamazaki and
  • Kazutoshi Gohara

5 February 2016

Micro- and nanobubbles (MNBs) are potentially useful for industrial applications such as the purification of wastewater and the promotion of physiological activities of living organisms. To develop such applications, we should understand their proper...

  • Article
  • Open Access
2 Citations
2,385 Views
14 Pages

9 December 2023

Black-odor water is prevalent in southeastern coastal regions of China, compromising both the aquatic ecosystem and urban aesthetics. Micro- and nano-bubbles (MNBs) aeration, identified as an innovative approach, offers potential improvements in wate...

  • Communication
  • Open Access
6 Citations
3,184 Views
10 Pages

Green Cleaning of 3D-Printed Polymeric Products by Micro-/Nano-Bubbles

  • Haoxiang Gao,
  • Fenghua Zhang,
  • Kangkang Tang,
  • Xianyu Luo,
  • Ziang Pu,
  • Jiuzhou Zhao,
  • Zhiwei Jiao and
  • Weimin Yang

5 June 2023

3D printing technology has been used to directly produce various actual products, ranging from engines and medicines to toys, especially due to its advantage in producing items of complicated, porous structures, which are inherently difficult to clea...

  • Review
  • Open Access
5 Citations
9,482 Views
41 Pages

Micro-Nanobubble Technology in Surface Cleaning and Defouling

  • Baljinder Singh,
  • Gunwoo Park,
  • Ja-Hyoung Ryu and
  • Myoung-Hwan Park

24 January 2025

The physicochemical characteristics of micro- and nanobubbles (MNBs) have attracted considerable interest owing to their potential use in various industries, such as water treatment, agriculture, healthcare, and environmental remediation. This review...

  • Article
  • Open Access
1 Citations
599 Views
15 Pages

10 October 2025

It is difficult to collect fine graphite particles because of the large size and small specific area of traditional flotation bubbles. The contrast experiment between nanobubble flotation and traditional flotation of micro-fine flake graphite in the...

  • Article
  • Open Access
88 Citations
11,609 Views
10 Pages

30 December 2018

The efficiency of ozone for the treatment of organics contaminated wastewater is limited by its slow dissolution rate and rapid decomposition in the aqueous phase. Micro-nano-bubbles (MNBs) are a novel method to prolong the reactivity of the ozone in...

  • Feature Paper
  • Article
  • Open Access
12 Citations
5,358 Views
11 Pages

21 February 2022

The objective of this study was to develop an alternative novel process technology for enhancing the rheological and functional properties of Greek-style yogurt (GSY). The GSY was formulated and prepared in the lab using micellar casein concentrate a...

  • Review
  • Open Access
16 Citations
4,720 Views
19 Pages

15 December 2023

Adsorption refrigerators are a compelling ecological alternative to compressor refrigerators; global warming forces us to constantly look for alternative sources of energy and cold. Cold production in adsorption chillers is based on the use of heat g...

  • Review
  • Open Access
21 Citations
10,279 Views
17 Pages

Overcoming the Fundamental Limit: Combustion of a Hydrogen-Oxygen Mixture in Micro- and Nano-Bubbles

  • Vitaly Svetovoy,
  • Alexander Postnikov,
  • Ilia Uvarov,
  • Remco Sanders and
  • Gijs Krijnen

3 February 2016

Combustion reactions quench in small volumes due to fast heat escape via the volume boundary. Nevertheless, the reaction between hydrogen and oxygen was observed in nano- and micro-bubbles. The bubbles containing a mixture of gases were produced in m...

  • Article
  • Open Access
252 Views
14 Pages

Improved Biological Control of Bacterial Leaf Blight Using a Surfactant Complex of CO2 Micro-Nanobubbles Coated with Crude Ethyl Acetate Extract of Trichoderma polyalthiae UBZSN2-1

  • Wasan Seemakram,
  • Thanapat Suebrasri,
  • Saranya Chantawong,
  • Sornamol Traiphop,
  • Sriprajak Krongsuk,
  • Jirawat Sanitchon,
  • Thanawan Gateta and
  • Sophon Boonlue

13 January 2026

The bacterium Xanthomonas oryzae pv. oryzae is an important pathogen that causes wilt leaf blight disease in rice (Oryza sativa L.), leading to a reduction in rice yield. Therefore, this study aimed to investigate the potential of a surfactant comple...

  • Article
  • Open Access
13 Citations
4,550 Views
16 Pages

14 February 2022

Soil aeration and plastic film mulching have been reported to accelerate plant growth and increase fruit yield by improving the rhizosphere soil–air environment. The aim of this study was to investigate plant growth, fruit yield, irrigation wat...

  • Article
  • Open Access
3 Citations
3,753 Views
14 Pages

Development of an Antibody Delivery Method for Cancer Treatment by Combining Ultrasound with Therapeutic Antibody-Modified Nanobubbles Using Fc-Binding Polypeptide

  • Yusuke Yano,
  • Nobuhito Hamano,
  • Kenshin Haruta,
  • Tomomi Kobayashi,
  • Masahiro Sato,
  • Yamato Kikkawa,
  • Yoko Endo-Takahashi,
  • Rui Tada,
  • Ryo Suzuki and
  • Yoichi Negishi
  • + 2 authors

A key challenge in treating solid tumors is that the tumor microenvironment often inhibits the penetration of therapeutic antibodies into the tumor, leading to reduced therapeutic efficiency. It has been reported that the combination of ultrasound-re...

  • Review
  • Open Access
16 Citations
4,791 Views
30 Pages

Enhancing Targeted Therapy in Breast Cancer by Ultrasound-Responsive Nanocarriers

  • Isaiah A. Edwards,
  • Flavia De Carlo,
  • Juliana Sitta,
  • William Varner,
  • Candace M. Howard and
  • Pier Paolo Claudio

Currently, the response to cancer treatments is highly variable, and severe side effects and toxicity are experienced by patients receiving high doses of chemotherapy, such as those diagnosed with triple-negative breast cancer. The main goal of resea...

  • Article
  • Open Access
897 Views
13 Pages

16 September 2025

Heterocyclic compounds in high-salinity wastewater are highly resistant to degradation, posing significant treatment challenges. A hybrid micro-nano bubble Fenton system (FT-MNBs) was developed to enhance Fe2+ activation via interfacial effects. The...

  • Article
  • Open Access
1 Citations
1,654 Views
16 Pages

Impact of Hydrodynamic Cavitation Pretreatment on Sodium Oleate Adsorption onto Diaspore and Kaolinite Surfaces

  • Weiguang Zhou,
  • Haobin Wei,
  • Yangge Zhu,
  • Yufeng Long,
  • Yanfei Chen and
  • Yuesheng Gao

18 September 2024

To investigate how hydrodynamic cavitation (HC) affects the adsorption of sodium oleate (NaOl) on diaspore and kaolinite surfaces, a comparative study on NaOl adsorption was conducted under different conditions. The flotation and separation of the mi...

  • Article
  • Open Access
6 Citations
2,034 Views
16 Pages

3 July 2024

Flotation-introduced nanobubbles were expected to be an efficient and economical method to recover fine muscovite. This study aimed to explore the mechanism of the change appearing in flotation after introducing nanobubbles through micro-flotation, p...

  • Article
  • Open Access
40 Citations
7,589 Views
13 Pages

Surface Composition and Preparation Method for Oxygen Nanobubbles for Drug Delivery and Ultrasound Imaging Applications

  • Muhammad Saad Khan,
  • Jangsun Hwang,
  • Kyungwoo Lee,
  • Yonghyun Choi,
  • Jaehee Jang,
  • Yejin Kwon,
  • Jong Wook Hong and
  • Jonghoon Choi

2 January 2019

Phospholipids have been widely investigated for the preparation of liposomes, and micro and nanobubbles. They comprise biocompatible and biodegradable molecules and offer simple preparation with a variety of functions in diagnostic and therapeutic ap...

  • Article
  • Open Access
5 Citations
2,871 Views
17 Pages

31 March 2025

PFASs, or per- and polyfluoroalkyl substances, comprise a diverse group of synthetic chemicals known for their widespread use, persistence, and potential environmental and health risks. The sonolytic treatment of PFASs is one of the technologies with...

  • Article
  • Open Access
7 Citations
2,158 Views
11 Pages

Due to the weak hydrophobicity of styrene phosphoric acid (SPA), the amount used as a collector for rutile flotation is too large, resulting in high beneficiation costs. In this study, SPA was modified by nanobubbles to enhance its hydrophobicity. In...

  • Review
  • Open Access
4 Citations
3,194 Views
13 Pages

17 September 2024

In recent years, ultrasound-stimulated microbubbles (USMBs) have gained great attention because of their wide theranostic applications. However, due to their micro-size, reaching the targeted site remains a challenge. At present, ultrasound-stimulate...

  • Feature Paper
  • Review
  • Open Access
31 Citations
7,908 Views
25 Pages

11 September 2022

Breast cancer is the most common type of cancer and it is treated with surgical intervention, radiotherapy, chemotherapy, or a combination of these regimens. Despite chemotherapy’s ample use, it has limitations such as bioavailability, adverse side e...

  • Article
  • Open Access
6 Citations
2,435 Views
12 Pages

Generation of Nano-Bubbles by NaHCO3 for Improving the FO Membrane Performance

  • Shilin Zhou,
  • Yuzhe Zhou,
  • Jin He,
  • Yuwen Lai,
  • Yanchun Li,
  • Wentao Yan,
  • Yong Zhou and
  • Congjie Gao

Thin-film composite (TFC) polyamide membranes have a wide range of applications in forward osmosis, but tuning the water flux remains a significant challenge due to concentration polarization. The generation of nano-sized voids within the polyamide r...

  • Article
  • Open Access
3 Citations
7,833 Views
18 Pages

19 July 2023

Determining how to apply hydrogen as a therapeutic/preventive antioxidant for oxidative-stress-related diseases practically in daily life has not been studied. The effects of bathtubs and buckets filled with hydrogen water (41 °C, >10 min bath...

  • Article
  • Open Access
2,863 Views
19 Pages

Substantial boosts in the low-energy nano-oxygenation of incoming process water were achieved at a municipal wastewater treatment plant (WWTP) upstream of activated sludge (AS) aeration lanes on a single-pass basis by means of an electric field nanob...

  • Article
  • Open Access
2 Citations
3,023 Views
11 Pages

Micro- and nanobubbles are tiny gas bubbles that are smaller than 100 μm and 1 μm, respectively. This study investigated the impact of electric field ozone nanobubbles (EF-ONBs) on the purification of both deionised and aquaculture water bodies...

  • Article
  • Open Access
38 Citations
5,449 Views
13 Pages

Theoretical and Experimental Gas Volume Quantification of Micro- and Nanobubble Ultrasound Contrast Agents

  • Eric C. Abenojar,
  • Ilya Bederman,
  • Al C. de Leon,
  • Jinle Zhu,
  • Judith Hadley,
  • Michael C. Kolios and
  • Agata A. Exner

The amount of gas in ultrasound contrast agents is related to their acoustic activity. Because of this relationship, gas volume has been used as a key variable in normalizing the in vitro and in vivo acoustic behavior of lipid shell-stabilized bubble...

  • Article
  • Open Access
1,589 Views
10 Pages

1 July 2025

In bulk liquid or on solid surfaces, nanobubbles (NBs) are gaseous domains at the nanoscale. They stand out due to their extended (meta)stability and great potential for use in practical settings. However, due to the high energy cost of bubble genera...

  • Article
  • Open Access
2 Citations
2,867 Views
11 Pages

Cooking Delicacy with Ice—Nanobubble Isolation Switches Stewing to ‘BBQ’

  • Qiankang Si,
  • Ruoyang Zhao,
  • Feng Gao,
  • Jun Guo,
  • Feng Zhang and
  • Liping Wang

30 January 2023

The key role of ice in cooking has been neglected. Here, we found negatively charged bulk nanobubbles (BNBs: average size ~60 nm and zeta potential <−20 mV) can be generated in ice-melted water through freeze/thaw-induced cavitation when we studie...

  • Article
  • Open Access
5 Citations
2,059 Views
13 Pages

31 October 2024

This study focuses on developing high-performance electrodes by applying micro/nano structures to aluminum mesh electrodes and evaluating their electrochemical performance through the electroflotation process. First, the most suitable electrode mater...

  • Article
  • Open Access
8 Citations
2,870 Views
16 Pages

Cement Composites with Graphene Nanoplatelets and Recycled Milled Carbon Fibers Dispersed in Air Nanobubble Water

  • Anastasia I. Patrinou,
  • Eirini Tziviloglou,
  • Athanasios Varoutoglou,
  • Evangelos P. Favvas,
  • Athanasios C. Mitropoulos,
  • George Z. Kyzas and
  • Zoi S. Metaxa

14 August 2022

The individual effect of nano- and micro-carbon-based fillers on the mechanical and the electrical properties of cement paste were experimentally examined in this study. The objective of the study was to separately examine the effects of size and mor...

  • Feature Paper
  • Article
  • Open Access
7 Citations
3,705 Views
19 Pages

23 January 2024

This study explores the potential of laser-induced nano-photon-poration as a non-invasive technique for the intracellular delivery of micro/macromolecules at the single-cell level. This research proposes the utilization of gold-coated spiky polymeric...

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