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6,553 Results Found

  • Article
  • Open Access
19 Citations
5,394 Views
15 Pages

21 October 2022

The manufacturing sector is a fast-growing sector demanded by the increasing population. The adoption of information technology is a boon in the manufacturing industry. The industrial transformation from the third generation to the fourth generation...

  • Article
  • Open Access
10 Citations
2,624 Views
14 Pages

14 December 2021

Additive manufacturing (AM) is gaining significant importance, as demand for customized products is increasing nowadays. AM is one of the disruptive technologies of Industry 4.0, which can reduce waste generation, enabling sustainability. The adoptio...

  • Article
  • Open Access
20 Citations
6,370 Views
26 Pages

20 February 2023

The global market for Additive Manufacturing (AM) is expected to grow, which may increase the prominence of sustainability aspects in the manufacturing process. A growing number of AM academics and practitioners have started to pay attention to the e...

  • Article
  • Open Access
20 Citations
5,921 Views
18 Pages

19 October 2022

Green initiatives have been widely introduced and have contributed to attaining sustainability and improving performance for supply chain management. However, only a few studies focus on green supply chain management (GSCM) practices in Vietnam. Henc...

  • Review
  • Open Access
7 Citations
4,399 Views
44 Pages

Advancements and Perspectives in Additive Manufacturing of Tungsten Alloys and Composites: Challenges and Solutions

  • Mehrdad Zarinejad,
  • Yunxiang Tong,
  • Mojtaba Salehi,
  • Chengfa Mu,
  • Nian Wang,
  • Yonglong Xu,
  • Sajjad Rimaz,
  • Lintao Tian,
  • Kai Xiang Kuah and
  • Xiaotong Chen

20 July 2024

This review explores additive manufacturing (AM) for refractory tungsten (W) and its alloys, highlighting the primary challenges and determining factors in the AM of pure W, W alloys and composites. The challenges mainly arise from W’s high mel...

  • Article
  • Open Access
4 Citations
2,319 Views
22 Pages

8 April 2024

In addressing the issue of climate change, the Chinese government has established a definitive objective to attain its peak carbon emissions by 2030 and strive for carbon neutrality by 2060. This effort aims to progressively achieve a state of net-ze...

  • Review
  • Open Access
68 Citations
18,355 Views
23 Pages

Therapeutic antibody technology heavily dominates the biologics market and continues to present as a significant industrial interest in developing novel and improved antibody treatment strategies. Many noteworthy advancements in the last decades have...

  • Review
  • Open Access
152 Citations
17,707 Views
17 Pages

Interoperability in Smart Manufacturing: Research Challenges

  • Abe Zeid,
  • Sarvesh Sundaram,
  • Mohsen Moghaddam,
  • Sagar Kamarthi and
  • Tucker Marion

Recent advances in manufacturing technology, such as cyber–physical systems, industrial Internet, AI (Artificial Intelligence), and machine learning have driven the evolution of manufacturing architectures into integrated networks of automation...

  • Article
  • Open Access
36 Citations
27,955 Views
24 Pages

21 May 2022

In this study we explored the challenges involved in Lean Transformation and implementation in the manufacturing sector. Using survey data from 50 North American manufacturing organizations, we examined the challenges involved in implementing and sus...

  • Feature Paper
  • Review
  • Open Access
120 Citations
20,189 Views
20 Pages

Challenges Associated with Implementing 5G in Manufacturing

  • Eoin O’Connell,
  • Denis Moore and
  • Thomas Newe

12 June 2020

5G networks will change several industries, including manufacturing. 5G has the potential to become the future communication platform of choice for many industries and in particular the manufacturing sector, driving the future of Industry 4.0 and sma...

  • Opinion
  • Open Access
52 Citations
27,818 Views
16 Pages

Emerging Challenges and Opportunities in Pharmaceutical Manufacturing and Distribution

  • Miriam Sarkis,
  • Andrea Bernardi,
  • Nilay Shah and
  • Maria M. Papathanasiou

3 March 2021

The rise of personalised and highly complex drug product profiles necessitates significant advancements in pharmaceutical manufacturing and distribution. Efforts to develop more agile, responsive, and reproducible manufacturing processes are being co...

  • Review
  • Open Access
53 Citations
9,542 Views
24 Pages

19 September 2021

Petri nets are a useful mathematical formalism for specification of manufacturing systems, supported by various analysis and verification methods. The progress made in automating control systems and the widespread use of Industry 4.0 pose a number of...

  • Review
  • Open Access
4 Citations
10,776 Views
24 Pages

In-Space Manufacturing: Technologies, Challenges, and Future Horizons

  • Subin Antony Jose,
  • Jordan Jackson,
  • Jayden Foster,
  • Terrence Silva,
  • Ethan Markham and
  • Pradeep L. Menezes

In-space manufacturing represents a transformative frontier in space exploration and industrial production, offering the potential to revolutionize how goods are produced and resources are utilized beyond Earth. This paper explores the multifaceted a...

  • Article
  • Open Access
8 Citations
4,700 Views
16 Pages

Digitalization is boosting the manufacturing industry’s shift to smart manufacturing systems, which will efficiently utilize the potential of new technologies for their business outcomes and value. However, the literature shows that manufacturing com...

  • Review
  • Open Access
18 Citations
11,190 Views
23 Pages

Soft Robot Design, Manufacturing, and Operation Challenges: A Review

  • Getachew Ambaye,
  • Enkhsaikhan Boldsaikhan and
  • Krishna Krishnan

Advancements in smart manufacturing have embraced the adoption of soft robots for improved productivity, flexibility, and automation as well as safety in smart factories. Hence, soft robotics is seeing a significant surge in popularity by garnering c...

  • Review
  • Open Access
211 Citations
29,464 Views
32 Pages

Review on Additive Manufacturing of Multi-Material Parts: Progress and Challenges

  • Seymur Hasanov,
  • Suhas Alkunte,
  • Mithila Rajeshirke,
  • Ankit Gupta,
  • Orkhan Huseynov,
  • Ismail Fidan,
  • Frank Alifui-Segbaya and
  • Allan Rennie

Additive manufacturing has already been established as a highly versatile manufacturing technique with demonstrated potential to completely transform conventional manufacturing in the future. The objective of this paper is to review the latest progre...

  • Review
  • Open Access
17 Citations
28,934 Views
38 Pages

Challenges and Opportunities in the Implementation of AI in Manufacturing: A Bibliometric Analysis

  • Lorena Espina-Romero,
  • Humberto Gutiérrez Hurtado,
  • Doile Ríos Parra,
  • Rafael Alberto Vilchez Pirela,
  • Rosa Talavera-Aguirre and
  • Angélica Ochoa-Díaz

3 October 2024

This study explores the evolution and impact of research on the challenges and opportunities in the implementation of artificial intelligence (AI) in manufacturing between 2019 and August 2024. By addressing the growing integration of AI technologies...

  • Review
  • Open Access
33 Citations
6,082 Views
23 Pages

21 August 2020

The physical architecture of materials plays an integral role in determining material properties and functionality. While many processing techniques now exist for fabricating parts of any shape or size, a couple of techniques have emerged as facile a...

  • Review
  • Open Access
24 Citations
11,661 Views
27 Pages

Enabling mRNA Therapeutics: Current Landscape and Challenges in Manufacturing

  • Maryam Youssef,
  • Cynthia Hitti,
  • Julia Puppin Chaves Fulber and
  • Amine A. Kamen

9 October 2023

Recent advances and discoveries in the structure and role of mRNA as well as novel lipid-based delivery modalities have enabled the advancement of mRNA therapeutics into the clinical trial space. The manufacturing of these products is relatively simp...

  • Article
  • Open Access
2 Citations
2,421 Views
26 Pages

Additive Manufacturing of Copper—A Survey on Current Needs and Challenges

  • Moritz Benedikt Schäfle,
  • Michel Fett,
  • Julian Gärtner and
  • Eckhard Kirchner

Additive manufacturing (AM) of copper is subject to dynamic development regarding available processes and the quality of produced parts. While challenging, AM processes for copper provide parts with a quality comparable to other metallic material gro...

  • Review
  • Open Access
913 Views
30 Pages

1 September 2025

The integration of sawmilling with prefabrication manufacturing presents a critical opportunity to enhance the efficiency, sustainability, and quality of timber construction in Australia. While prefabrication offers substantial benefits, including re...

  • Review
  • Open Access
23 Citations
4,680 Views
17 Pages

21 February 2022

The aim of this review is to present the recent developments in heat pipe production, which respond to the current technical problems related to the wide implementation of this technology. A novel approach in HP manufacturing is to utilise hi-tech ad...

  • Article
  • Open Access
5 Citations
8,231 Views
21 Pages

10 October 2024

This study explores the challenges and solutions faced by manufacturing companies in one industry when integrating green suppliers into their supply chains. The FGD transcripts were analyzed using NVivo 12 Pro for coding and thematic analysis, which...

  • Review
  • Open Access
3 Citations
2,474 Views
28 Pages

Smart Manufacturing for High-Performance Materials: Advances, Challenges, and Future Directions

  • Subin Antony Jose,
  • Alex Tonner,
  • Marc Feliciano,
  • Teddy Roy,
  • Aidan Shackleford and
  • Pradeep L. Menezes

13 May 2025

Smart manufacturing utilizes advanced computing technologies to enhance adaptability within traditional mass production systems. This enables the creation of highly specialized products on demand, maintaining efficiency and cost-effectiveness. Integr...

  • Review
  • Open Access
227 Citations
25,478 Views
25 Pages

Embroidery and Related Manufacturing Techniques for Wearable Antennas: Challenges and Opportunities

  • Aris Tsolis,
  • William G. Whittow,
  • Antonis A. Alexandridis and
  • J. C. Vardaxoglou

This paper will review the evolution of wearable textile antennas over the last couple of decades. Particular emphasis will be given to the process of embroidery. This technique is advantageous for the following reasons: (i) bespoke or mass produced...

  • Review
  • Open Access
49 Citations
16,312 Views
28 Pages

A Review on AI for Smart Manufacturing: Deep Learning Challenges and Solutions

  • Jiawen Xu,
  • Matthias Kovatsch,
  • Denny Mattern,
  • Filippo Mazza,
  • Marko Harasic,
  • Adrian Paschke and
  • Sergio Lucia

17 August 2022

Artificial intelligence (AI) has been successfully applied in industry for decades, ranging from the emergence of expert systems in the 1960s to the wide popularity of deep learning today. In particular, inexpensive computing and storage infrastructu...

  • Article
  • Open Access
13 Citations
3,970 Views
17 Pages

18 August 2020

This paper presents the manufacturing challenges of a transverse flux alternator for an aerospace application. For fault tolerance, four independent isolated phases are required to deliver a specific power at low speeds, whilst at over speed, there i...

  • Review
  • Open Access
3 Citations
4,995 Views
39 Pages

AI Trustworthiness in Manufacturing: Challenges, Toolkits, and the Path to Industry 5.0

  • M. Nadeem Ahangar,
  • Z. A. Farhat and
  • Aparajithan Sivanathan

11 July 2025

The integration of Artificial Intelligence (AI) into manufacturing is transforming the industry by advancing predictive maintenance, quality control, and supply chain optimisation, while also driving the shift from Industry 4.0 towards a more human-c...

  • Article
  • Open Access
10 Citations
8,129 Views
19 Pages

5 July 2023

Since the start of the industrial revolution, the manufacturing industry has been essential for economic growth but has also contributed to environmental pollution problems. The United Nations declared the 2030 Sustainable Development Goals (SDG) age...

  • Review
  • Open Access
8 Citations
8,362 Views
26 Pages

Processes and Challenges for the Manufacturing of Lyocell Fibres with Alternative Agricultural Feedstocks

  • Lelia Lawson,
  • Madison Ford,
  • Md. Saiful Hoque,
  • Wade Chute,
  • David C. Bressler and
  • Patricia I. Dolez

28 November 2023

Lyocell man-made cellulosic fibres (L-MMCF) have been commercially available since the mid-1990’s, with the typical feedstock prepared from tree pulp or cotton linters. In recent years, there have been advancements in the utilisation of high al...

  • Perspective
  • Open Access
614 Views
24 Pages

Additive Manufacturing for Next-Generation Batteries: Opportunities, Challenges, and Future Outlook

  • Antreas Kantaros,
  • Theodore Ganetsos,
  • Evangelos Pallis,
  • Michail Papoutsidakis and
  • Nikolaos Laskaris

9 November 2025

The elevated needs for high-performance energy storage, dictated by electrification, renewable sources integration, and the global increase in interconnected devices, have placed batteries to the forefront of technological research. Additive manufact...

  • Review
  • Open Access
110 Citations
10,749 Views
26 Pages

31 August 2020

Nowadays, environmental pollution due to synthetic polymers represents one of the biggest worldwide challenges. As demonstrated in numerous scientific articles, plant-based nanocellulose (NC) is a biodegradable and nontoxic material whose mechanical,...

  • Review
  • Open Access
86 Citations
20,054 Views
15 Pages

Silicon Solar Cells: Trends, Manufacturing Challenges, and AI Perspectives

  • Marisa Di Sabatino,
  • Rania Hendawi and
  • Alfredo Sanchez Garcia

7 February 2024

Photovoltaic (PV) installations have experienced significant growth in the past 20 years. During this period, the solar industry has witnessed technological advances, cost reductions, and increased awareness of renewable energy’s benefits. As m...

  • Article
  • Open Access
4 Citations
6,630 Views
20 Pages

With rising concerns about the social and environmental impacts of industrial and manufacturing waste, scientists and engineers have sought solutions to the burdens of waste which do not simply involve burying, burning, dumping or diluting. Our purpo...

  • Communication
  • Open Access
18 Citations
8,989 Views
9 Pages

Challenges and Solutions for Commercial Scale Manufacturing of Allogeneic Pluripotent Stem Cell Products

  • Brian Lee,
  • Breanna S. Borys,
  • Michael S. Kallos,
  • Carlos A. V. Rodrigues,
  • Teresa P. Silva and
  • Joaquim M. S. Cabral

Allogeneic cell therapy products, such as therapeutic cells derived from pluripotent stem cells (PSCs), have amazing potential to treat a wide variety of diseases and vast numbers of patients globally. However, there are various challenges related to...

  • Perspective
  • Open Access
3 Citations
4,275 Views
29 Pages

The Role of 3D Printing in Advancing Automated Manufacturing Systems: Opportunities and Challenges

  • Antreas Kantaros,
  • Christos Drosos,
  • Michail Papoutsidakis,
  • Evangelos Pallis and
  • Theodore Ganetsos

The integration of 3D printing technologies in automated manufacturing systems marks a significant progression in the manufacturing industry, enabling elevated degrees of customization, efficiency, and sustainability. This paper explores the synergy...

  • Review
  • Open Access
229 Citations
32,038 Views
20 Pages

17 January 2022

Industrial robots and associated control methods are continuously developing. With the recent progress in the field of artificial intelligence, new perspectives in industrial robot control strategies have emerged, and prospects towards cognitive robo...

  • Review
  • Open Access
4 Citations
3,890 Views
38 Pages

A Review of Non-Powder-Bed Metal Additive Manufacturing: Techniques and Challenges

  • Jie Xu,
  • Yifan Fei,
  • Yuanzhe Zhu,
  • Wei Yu,
  • Donggang Yao and
  • Jack G. Zhou

26 September 2024

Metal additive manufacturing has significantly evolved since the 1990s, achieving a market valuation of USD 6.36 billion in 2022, with an anticipated compound annual growth rate of 24.2% from 2023 to 2030. While powder-bed-based methods like powder b...

  • Article
  • Open Access
16 Citations
4,418 Views
21 Pages

15 February 2022

Coordinating the digital transformation of globally dispersed factories within international manufacturing networks has become a critical issue for competitiveness, yet there has been limited attention paid to this issue in previous research. Therefo...

  • Review
  • Open Access
4 Citations
4,737 Views
44 Pages

Aluminum Laser Additive Manufacturing: A Review on Challenges and Opportunities Through the Lens of Sustainability

  • Mohammad Javad Yadegari,
  • Alessandra Martucci,
  • Sara Biamino,
  • Daniele Ugues,
  • Laura Montanaro,
  • Paolo Fino and
  • Mariangela Lombardi

19 February 2025

The manufacturing sector is a major contributor to global energy consumption and greenhouse gas emissions, positioning sustainability as a critical priority. Aluminum, valued for its lightweight and recyclable properties, plays a vital role in advanc...

  • Article
  • Open Access
3 Citations
1,033 Views
24 Pages

Strategic Framework for Additive Manufacturing with Smart Polymer Composites: A Pathway to Net-Zero Manufacturing

  • Alok Yadav,
  • Rajiv Kumar Garg,
  • Anish Sachdeva,
  • Karishma M. Qureshi and
  • Mohamed Rafik Noor Mohamed Qureshi

14 May 2025

Despite manufacturing firms recognizing the potential benefits of polymer-based smart materials (PBSM) in additive manufacturing (AM), their large-scale integration remains limited. As manufacturing firms strive toward net-zero emissions (NZE) and su...

  • Review
  • Open Access
16 Citations
5,807 Views
17 Pages

rAAV Manufacturing: The Challenges of Soft Sensing during Upstream Processing

  • Cristovão Freitas Iglesias,
  • Milica Ristovski,
  • Miodrag Bolic and
  • Miroslava Cuperlovic-Culf

Recombinant adeno-associated virus (rAAV) is the most effective viral vector technology for directly translating the genomic revolution into medicinal therapies. However, the manufacturing of rAAV viral vectors remains challenging in the upstream pro...

  • Review
  • Open Access
6 Citations
2,660 Views
26 Pages

Advances and Challenges in Predictive Modeling for Additive Manufacturing of Dissimilar Metals and Complex Alloys

  • Debajyoti Adak,
  • Praveen Sreeramagiri,
  • Somnath Roy and
  • Ganesh Balasubramanian

18 August 2023

We present a scrutiny on the state of the art and applicability of predictive methods for additive manufacturing (AM) of metals, alloys, and compositionally complex metallic materials, to provide insights from the computational models for AM process...

  • Article
  • Open Access
20 Citations
9,935 Views
18 Pages

6 January 2023

Environmental management accounting (EMA) implementation challenges within supply chain management systems (SCMSs) and environmental awareness in emerging economies should be addressed for sustainable development. Therefore, this study explores EMA i...

  • Review
  • Open Access
80 Citations
16,254 Views
31 Pages

3 November 2022

The scientific community is and has constantly been working to innovate and improve the available technologies in our use. In that effort, three-dimensional (3D) printing was developed that can construct 3D objects from a digital file. Three-dimensio...

  • Review
  • Open Access
17 Citations
8,055 Views
37 Pages

16 January 2025

This bibliographic analysis explores the evolving landscape of additive manufacturing (AM) in the context of Industry 4.0 and the emerging paradigms of Industry 5.0. This research critically examines the key literature and scholarly works to clarify...

  • Review
  • Open Access
128 Citations
27,287 Views
30 Pages

Wire arc additive manufacturing (WAAM) is an emerging and promising technology for producing medium-to-large-scale metallic components/structures for different industries, i.e., aerospace, automotive, shipbuilding, etc. It is now a feasible alternati...

  • Review
  • Open Access
9 Citations
4,869 Views
27 Pages

7 November 2024

Cold spray additive manufacturing (CSAM) is a cutting-edge high-speed additive manufacturing process enabling the production of high-strength components without relying on traditional high-temperature methods. Unlike other techniques, CSAM produces o...

  • Review
  • Open Access
96 Citations
14,194 Views
25 Pages

Challenges in Solvent-Free Methods for Manufacturing Electrodes and Electrolytes for Lithium-Based Batteries

  • Nina Verdier,
  • Gabrielle Foran,
  • David Lepage,
  • Arnaud Prébé,
  • David Aymé-Perrot and
  • Mickaël Dollé

20 January 2021

With the ever-growing energy storage notably due to the electric vehicle market expansion and stationary applications, one of the challenges of lithium batteries lies in the cost and environmental impacts of their manufacture. The main process employ...

  • Review
  • Open Access
77 Citations
11,668 Views
60 Pages

12 August 2021

Bulk Metallic Glasses (BMG) are metallic alloys that have the ability to solidify in an amorphous state. BMGs show enhanced properties, for instance, high hardness, strength, and excellent corrosion and wear resistance. BMGs produced by conventional...

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