Although many potential causes have been established for recurrent implantation failure (RIF) and recurrent miscarriage (RM), about 50% of these remain idiopathic. Scientific research is focused on immunological risk factors. In the present study, we...
Individuals with Inflammatory Bowel Disease (IBD) are characterized by an increased vulnerability to complications stemming from infectious diseases. While these patients do not inherently face a heightened risk of SARS-CoV-2 infection compared to th...
14 July 2021
Although vaccination is carried out worldwide, the vaccination rate varies greatly. As of 24 May 2021, in some countries, the proportion of the population fully vaccinated against COVID-19 has exceeded 50%, but in many countries, this proportion is s...
For decades, understanding the dynamics of infectious diseases and halting their spread has been a major focus of mathematical modelling and epidemiology. The stochastic SIRS (susceptible–infectious–recovered–susceptible) reaction&n...
This study was conducted to investigate the feasibility of improving fertility in dairy cows via immunization against inhibin. Thirty-two cows were divided into Control (n = 11), Low-dose (n = 10) and High-dose (n = 11) groups. The High-dose and Low-...
The feeding rate is critical for fish growth and the feed conversion ratio (FCR). Prior research has primarily evaluated the optimal feeding rate by examining growth performance and the FCR. Given the high cost of koi as an ornamental fish, it is ess...
Since the introduction of hepatitis B virus (HBV) vaccines, the numbers of HBV infections and complications have significantly decreased. However, the evidence on whether primary vaccination of infants confers lifelong immunity varies. We aimed to as...
A 10-week feeding trial was conducted to evaluate the effects of different feeding rates on growth performance, nutrient deposition, plasma metabolite, and immunity of juvenile starry flounder. Fish (initial mean body weight, 183.6 ± 2.3 g) we...
Cardiac pacemakers are standard implantable medical devices that regulate and treat heart rhythm disorders, primarily aiming to improve patient health outcomes. This study presents the systematic design, implementation, and simulation-based validatio...
Norovirus is a leading global cause of viral gastroenteritis, significantly affecting mortality, morbidity, and healthcare costs. This paper develops and analyzes a stochastic SEIQR epidemic model for norovirus dynamics, incorporating temporal immuni...
In this paper, an SVIR epidemic model with temporary immunities and general incidence rates is constructed and analyzed. By utilizing Lyapunov functions, we prove the existence and uniqueness of the positive global solution of the constructed model,...
This study aimed to elucidate the effects of different photoperiods (0 L:24 D, 6 L:18 D, 12 L:12 D, 18 L:6 D, 24 L:0 D, “Light (L) and Dark (D)”) on the growth performance and physiological responses of the juvenile scalloped spiny lobste...
At many modern dairy farms, calves raised in barns are kept in individual stalls separated by solid partitions, which act as barriers. Ventilation fans blowing air perpendicular to these stalls only provide the optimal airflow to the first few calves...
Background and Objectives: Chronic total occlusion (CTO) is a complex lesion of coronary artery disease (CAD) with a detection rate of approximately 25% on coronary angiography. CTO patients generally experience poor quality of life and prognosis. Th...
The etiology of Inflammatory Bowel Disease (IBD) is not fully understood but is believed to involve a dysregulated immune response to intestinal microbiota in genetically susceptible individuals. Individuals with IBD are at increased risk of infectio...
5 March 2014
Background: The Zhejiang Immunization Information System (ZJIIS) was established in 2004. This study described the coverage rates of NIP vaccines in Zhejiang Province using the ZJIIS. Methods: Children aged 1–7 years (born from 1 January 2005 to 31...
The dropout rate is one of the determinants of immunization coverage and program performance, program continuity, and follow-up. The dropout rate refers to the proportion of vaccine recipients who did not finish their vaccination schedules, and it is...
A systematic review with a meta-analysis was performed to gather available evidence on the effectiveness of monoclonal antibody nirsevimab in the prevention of lower respiratory tract diseases (LRTDs) due to respiratory syncytial virus (RSV) in child...
Using a mathematical model for COVID-19 incorporating data on excess of mortality compared to the corresponding period of the previous year obtained from the daily monitoring of mortality in Spain (MoMo), the prediction of total number of casualties...
Background: With the development of immunology, immune checkpoint inhibitors (ICIs) have been widely used in various cancer treatments. Although some patients can benefit from ICIs, other patients have no response to ICIs or suffer from hyperprogress...
We consider the problem of short term immunization of a bond-like obligation with respect to changes in interest rates using a portfolio of bonds. In the case that the zero-coupon yield curve belongs to a fixed low-dimensional manifold, the problem i...
Protecting against unexpected yield curve, inflation, and longevity shifts are some of the most critical issues institutional and private investors must solve when managing post-retirement income benefits. This paper empirically investigates the perf...
Objective: To explore the problems with non-National Immunization Program vaccinations in Hubei Province and to provide the basis for follow-up vaccination and management. Methods: Vaccination data on non-NIP/NIP vaccine doses were extracted from the...
A new discrete Susceptible-Exposed-Infectious-Recovered (SEIR) epidemic model is proposed, and its properties of non-negativity and (both local and global) asymptotic stability of the solution sequence vector on the first orthant of the state-space a...
The largemouth bass ranavirus (LMBRaV) caused significant mortality and economic loss in the largemouth bass aquaculture industry around the world, including China. Vaccination is an efficient method for virus defense. In this study, an inactivated L...
10 June 2022
Post-marketing safety surveillance of new vaccines aimed to be administered during pregnancy is crucial to orchestrate efficient adverse events evaluation. This is of special relevance in the current landscape of new vaccines being introduced in the...
Litopenaeus vannamei, known as whiteleg shrimp, is susceptible to infection by pathogenic microorganisms such as viruses and bacteria. Therefore, the prevention of infections in this shrimp is important to regulate the outbreaks of pathogenic microor...
Stress responses can impact bladder cancer (BC) outcomes via immune–inflammatory pathway modulation. This study explores heart rate variability (HRV) associations with serum immune–inflammatory biomarkers, blood count inflammatory markers...
The blood transcriptome was examined in relation to disease severity in type I myotonic dystrophy (DM1) patients who participated in the Observational Prolonged Trial In DM1 to Improve QoL- Standards (OPTIMISTIC) study. This sought to (a) ascertain i...
Over 30 years after the first cancer vaccine clinical trial (CT), scientists still search the missing link between immunogenicity and clinical responses. A predictor able to estimate the outcome of cancer vaccine CTs would greatly benefit vaccine dev...
In the context of the COVID-19 epidemic, and on the basis of the Theory of Dynamical Systems, we propose a simple theoretical approach for the expansion of contagious diseases, with a particular focus on viral respiratory tracts. The infection develo...
Pre-clinical animal studies evaluating the ‘flash effect’ caused by ultra-high dose rate (≥40 Gy/s) favorably spares normal tissue from radiation-caused toxicity while maintaining anti-tumor effects like conventional (CONV) radiation....
The erythrocyte sedimentation rate (ESR) is used in canine medicine in several disorders, especially to evaluate the levels of inflammation. ESR is a valid inflammatory marker in canine leishmaniosis (CanL), being markedly increased in sick dogs. Thi...
The Public Health Agency of Canada recommends that 80% of high-risk persons, including adults aged ≥65 years and 18–64 years with certain comorbidities, be vaccinated against influenza. During the 2022–2023 influenza season, we conduct...
FLASH radiotherapy, or the delivery of a dose at an ultra-high dose rate (>40 Gy/s), has recently emerged as a promising tool to enhance the therapeutic index in cancer treatment. The remarkable sparing of normal tissues and equivalent tumor contr...
To enhance the logistics scheduling efficiency of automated guided vehicles (AGVs) in automated ports and achieve the orderly charging and battery swapping of AGVs as well as self-sufficient clean energy, this paper proposes an integrated optimizatio...
Introduction: Renal cell carcinomas (RCC) have been treated with immunotherapy for decades; the use of immune checkpoint inhibitors represents the most recent advance. In this review, we compare these new RCC immunotherapies, with a focus on achievin...
Cathepsins are lysosomal cysteine proteases belonging to the papain family and play crucial roles in intracellular protein degradation/turnover, hormone maturation, antigen processing, and immune responses. In the present study, 18 cathepsins were sy...
This paper presents the design of on-chip micro-antennas for package-scale galvanic isolators based on RF planar coupling. A step-by-step design procedure is proposed, which aims at the maximization of the weak electromagnetic coupling between the RX...
The implementation of medical drones can quickly and efficiently expand the coverage range of an area, allowing for a faster response to incidences of out-of-hospital cardiac arrest and improving the subsequent survival rate of such incidences, while...
Cervical cancer is the fourth most common cancer in females worldwide. Patients with stage III and IV cervical cancer based on the Federation of Gynecology and Obstetrics (FIGO) classification have higher recurrence rates. Because of organs at risk (...
Recommended vaccination at nine months of age with the measles-containing vaccine (MCV1) has been part of Ethiopia’s routine immunization program since 1980. A second dose of MCV (MCV2) was introduced in 2019 for children 15 months of age. We e...
The degree of antigenic drift in swine influenza A viruses (swIAV) has historically been regarded as minimal compared to that of human influenza A virus strains. However, as surveillance activities on swIAV have increased, more isolates have been cha...
We assessed the long-term persistence of humoral immunity against diphtheria in adults with childhood vaccination and the immunogenicity of a booster dose considering demographic, behavioural and vaccinating factors. We conducted a trial in 200 healt...
Childhood vaccination is crucial to protect young children from harmful infectious diseases. This study aimed to investigate the recent childhood immunization rate of recommended and additional vaccinations and identify the factors affecting the vacc...
Huanglongbing (HLB), or citrus greening, is a devastating disease impacting citrus trees worldwide, with severe effects particularly noted in Florida. Current strategies to combat HLB focus on aggressive replanting, despite the high susceptibility of...
Cattle fertility remains sub-optimal despite recent improvements in genetic selection. The extent to which an individual heifer fulfils her genetic potential can be influenced by fetal programming during pregnancy. This paper reviews the evidence tha...
Background/Objectives: The epidemiology of dermatomyositis (DM) and other idiopathic inflammatory myopathies (IIMs) remains not well established, especially in the Mediterranean region. We aimed to estimate the prevalence and incidence of IIM in a we...
There is evidence of the effect of probiotic intake on the immune system. However, the effect probiotics may have on the rate of aging is unknown. The aim of this study is to determine the effect of a probiotic blend on immunity, redox state, inflamm...
SARS-CoV-2 has spread worldwide, causing millions of deaths and leaving a significant proportion of people with long-term sequelae of COVID-19 (“post-COVID syndrome”). Whereas the precise mechanism of post-COVID syndrome is still unknown,...
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