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2,308 Results Found

  • Article
  • Open Access
1 Citations
1,115 Views
9 Pages

25 September 2025

Background: The microphone & receiver-in-ear (M&RIE) integrates two traditional hearing aid microphones, while an additional in-ear microphone helps preserve natural sound perception. However, the impact of this third microphone on hearing ai...

(This article belongs to the Section Otolaryngology)
  • Article
  • Open Access
1 Citations
3,254 Views
12 Pages

The Prevalence and Clinical Characteristics of MYO3A-Associated Hearing Loss in 15,684 Hearing Loss Patients

  • Karuna Maekawa,
  • Shin-ya Nishio,
  • Hiromitsu Miyazaki,
  • Yoko Ohta and ,
  • Naoki Oishi,
  • Misato Kasai,
  • Ai Yamamoto,
  • Mayuri Okami,
  • Koichiro Wasano and
  • Shin-ichi Usami
  • + 6 authors+ 1 author

16 January 2025

Background/Objectives: MYO3A belongs to the unconventional myosin superfamily, and the myosin IIIa protein localizes on the tip of the stereocilia of vestibular and cochlear hair cells. Deficiencies in MYO3A have been reported to cause the defor...

(This article belongs to the Section Human Genomics and Genetic Diseases)
  • Article
  • Open Access
3,616 Views
12 Pages

Prevalence and Clinical Characteristics of OTOGL-Associated Hearing Loss Identified in a Cohort of 7065 Japanese Patients with Hearing Loss

  • Karuna Maekawa,
  • Shin-ya Nishio,
  • Kotaro Ishikawa,
  • Masahiro Takahashi and ,
  • Kozo Kumakawa,
  • Mayuri Okami,
  • Hidekane Yoshimura,
  • Jun Nakayama,
  • Masato Teraoka and
  • Shin-ichi Usami
  • + 5 authors+ 0 author

23 January 2025

Background/Objectives: Hearing loss is one of the most common sensorineural impairments, and approximately 60% of early-onset cases are due to genetic variations. The otogelin-like protein, encoded by the OTOGL gene, is a component of the acellular m...

(This article belongs to the Section Human Genomics and Genetic Diseases)
  • Review
  • Open Access
3 Citations
4,837 Views
9 Pages

Hearing Aid in Vestibular-Schwannoma-Related Hearing Loss: A Review

  • Valerio Maria Di Pasquale Fiasca,
  • Flavia Sorrentino,
  • Martina Conti,
  • Giulia De Lucia and ,
  • Patrizia Trevisi,
  • Cosimo de Filippis,
  • Elisabetta Zanoletti and
  • Davide Brotto
  • + 3 authors+ 0 author

8 August 2023

(1) Background: Several types of hearing aids are available for the rehabilitation of vestibular-schwannoma (VS)-related hearing loss. There is a lack of recently published papers regarding this theme. The aim of the present work is to organize curre...

(This article belongs to the Special Issue Hearing and Balance in Acoustic Neuroma)
  • Article
  • Open Access
1,301 Views
13 Pages

11 March 2026

Background/Objectives: MYO7A is known to be the genetic cause of Usher syndrome type 1, as well as autosomal dominant and autosomal recessive non-syndromic hearing loss. In general, autosomal dominant MYO7A-associated hearing loss shows progressive h...

(This article belongs to the Section Human Genomics and Genetic Diseases)
  • Article
  • Open Access
3 Citations
3,478 Views
13 Pages

Detailed Clinical Features of PTPRQ-Associated Hearing Loss Identified in a Large Japanese Hearing Loss Cohort

  • Naoko Sakuma,
  • Shin-ya Nishio,
  • Shin-ichi Goto,
  • Yohei Honkura and ,
  • Kiyoshi Oda,
  • Hidehiko Takeda,
  • Marina Kobayashi,
  • Kozo Kumakawa,
  • Satoshi Iwasaki and
  • Shin-ichi Usami
  • + 12 authors+ 7 authors

12 April 2024

The PTPRQ gene has been identified as one of the genes responsible for non-syndromic sensorineural hearing loss (SNHL), and assigned as DFNA73 and DFNB84. To date, about 30 causative PTPRQ variants have been reported to cause SNHL. However, the detai...

(This article belongs to the Section Molecular Genetics and Genomics)
  • Article
  • Open Access
29 Citations
7,570 Views
17 Pages

Mid-Frequency Hearing Loss Is Characteristic Clinical Feature of OTOA-Associated Hearing Loss

  • Kenjiro Sugiyama,
  • Hideaki Moteki,
  • Shin-ichiro Kitajiri,
  • Tomohiro Kitano and ,
  • Shin-ya Nishio,
  • Tomomi Yamaguchi,
  • Keiko Wakui,
  • Satoko Abe,
  • Akiko Ozaki and
  • Shin-ichi Usami
  • + 10 authors+ 5 authors

16 September 2019

The OTOA gene (Locus: DFNB22) is reported to be one of the causative genes for non-syndromic autosomal recessive hearing loss. The copy number variations (CNVs) identified in this gene are also known to cause hearing loss, but have not been identifie...

(This article belongs to the Special Issue Genetic Epidemiology of Deafness)
  • Review
  • Open Access
77 Citations
16,104 Views
13 Pages

3 April 2020

There is an increasing global recognition of the negative impact of hearing loss, and its association to many chronic health conditions. The deficits and disabilities associated with profound unilateral hearing loss, however, continue to be under-rec...

(This article belongs to the Special Issue Therapies for Hearing Loss)
  • Feature Paper
  • Article
  • Open Access
7 Citations
4,676 Views
8 Pages

Prevalence of Hearing Loss in Dutch Newborns; Results of the Nationwide Well-Baby Newborn Hearing Screening Program

  • Rosanne B. van der Zee,
  • Noëlle N. Uilenburg,
  • Catharina (Kitty) P. B. van der Ploeg and
  • Evelien Dirks

16 February 2022

Background: Few studies report prevalence rates of hearing loss in newborns for nationwide populations. The Dutch well-baby newborn hearing screening covers almost all eligible children and has high participation rates for follow-up screening rounds...

(This article belongs to the Special Issue Hearing Loss: From Pathophysiology to Therapies and Habilitation)
  • Systematic Review
  • Open Access
12 Citations
3,243 Views
12 Pages

“Do You Hear What I Hear?” Speech and Voice Alterations in Hearing Loss: A Systematic Review

  • Arianna Di Stadio,
  • Jake Sossamon,
  • Pietro De Luca,
  • Iole Indovina and ,
  • Giovanni Motta,
  • Massimo Ralli,
  • Michael J. Brenner,
  • Elliot M. Frohman and
  • Gordon T. Plant
  • + 4 authors+ 0 author

20 February 2025

Background: Although hearing loss influences voice characteristics, such changes may be under-recognized during clinical consultations. This systematic review examines voice alterations in adults with post-lingual hearing loss, considering diagnostic...

(This article belongs to the Special Issue New Advances in the Management of Voice Disorders)
  • Review
  • Open Access
22 Citations
11,710 Views
9 Pages

Hearing Loss in Stickler Syndrome: An Update

  • Frederic R. E. Acke and
  • Els M. R. De Leenheer

1 September 2022

Stickler syndrome is a connective tissue disorder characterized by ocular, skeletal, orofacial and auditory manifestations. Its main symptoms are high myopia, retinal detachment, joint hypermobility, early osteoarthritis, cleft palate, midfacial hypo...

(This article belongs to the Special Issue Genetics in Stickler Syndrome)
  • Review
  • Open Access
1,299 Views
17 Pages

Connexins in Acquired Hearing Loss: Expanding Research Perspectives

  • Sihan Huang,
  • Jingyi Zhu,
  • Jifang Zhang,
  • Tianyu Gong and ,
  • Zhongyuan Fei,
  • Penghui Chen,
  • Shule Hou and
  • Jun Yang
  • + 3 authors+ 0 author

17 December 2025

Connexins, as key players in intercellular communication in the inner ear, are vital for maintaining normal hearing function. While numerous studies have explored their role in congenital hereditary hearing loss, the underlying mechanisms and therape...

(This article belongs to the Special Issue Genetic Research of Hearing Loss)
  • Article
  • Open Access
3 Citations
4,067 Views
16 Pages

Objectives: This study investigates Greek teenagers’ general knowledge and perception of hearing loss, hearing aid accessibility, and the challenges associated with hearing impairment. Methods: A 27-item self-reported questionnaire was develope...

  • Article
  • Open Access
13 Citations
4,686 Views
12 Pages

Self-Perception of Hearing Difficulties and Quality of Life in Individuals with Hearing Loss

  • Adriana Neves de Andrade,
  • Andrea Soares,
  • Magdalena Beata Skarzynska,
  • Piotr Henryk Skarzynski and ,
  • Milaine Dominici Sanfins and
  • Daniela Gil
  • + 1 author+ 0 author

29 September 2022

Objectives: To characterize the results of the Short Form Health Survey-36 (SF-36), Abbreviated Profile of Hearing Aid Benefit (APHAB), and the Hearing Handicap Inventory for Adults (HHIA) questionnaires in individuals with mild to moderate sensorine...

  • Review
  • Open Access
254 Citations
68,001 Views
34 Pages

Noise-Induced Hearing Loss

  • Nirvikalpa Natarajan,
  • Shelley Batts and
  • Konstantina M. Stankovic

17 March 2023

Noise-induced hearing loss (NIHL) is the second most common cause of sensorineural hearing loss, after age-related hearing loss, and affects approximately 5% of the world’s population. NIHL is associated with substantial physical, mental, socia...

(This article belongs to the Special Issue Integration of Clinical and Molecular Studies in Understanding the Pathogenesis of Hearing Loss: From Cause to Cure)
  • Article
  • Open Access
6 Citations
4,452 Views
13 Pages

Prevalence and Clinical Characteristics of Hearing Loss Caused by MYH14 Variants

  • Ken Hiramatsu,
  • Shin-ya Nishio,
  • Shin-ichiro Kitajiri,
  • Tomohiro Kitano and ,
  • Hideaki Moteki,
  • Shin-ichi Usami and
  • on behalf of the Deafness Gene Study Consortium
  • + 2 authors+ 0 author

15 October 2021

Variants in MYH14 are reported to cause autosomal dominant nonsyndromic hereditary hearing loss (ADNSHL), with 34 variants reported to cause hearing loss in various ethnic groups. However, the available information on prevalence, as well as with rega...

(This article belongs to the Section Human Genomics and Genetic Diseases)
  • Feature Paper
  • Article
  • Open Access
4 Citations
4,820 Views
9 Pages

Evaluation of the Recovery of Idiopathic Sudden Sensorineural Hearing Loss Based on Estimated Hearing Disorders

  • Tadashi Nishimura,
  • Tadao Okayasu,
  • Chihiro Morimoto,
  • Sakie Akasaka and ,
  • Tadashi Kitahara and
  • Hiroshi Hosoi
  • + 1 author+ 0 author

1 September 2022

Various prognostic factors for idiopathic sudden sensorineural hearing loss (SSNHL) have been reported. Hearing loss directly derived from idiopathic SSNHL is important for understanding underlying pathogenesis and outcomes. We assessed the usefulnes...

  • Article
  • Open Access
15 Citations
5,456 Views
13 Pages

Experiences of Hearing Parents of Children with Hearing Loss: A Qualitative Study

  • Gül Dikeç,
  • Eda Türk,
  • Esin Yüksel,
  • Kübra Çelebi and
  • Meltem Özdemir

29 June 2023

This qualitative study was carried out with a phenomenological design to determine the life experiences of the parents of children with hearing loss. The study sample consisted of twenty parents, who did not have hearing loss, of children with hearin...

(This article belongs to the Special Issue Advances in Rehabilitation of Children with Disabilities)
  • Brief Report
  • Open Access
3 Citations
4,607 Views
13 Pages

Efficacy of Hearing Aids in Patients with Hearing Difficulties in Noise: Focus on Hidden Hearing Loss

  • Marc Boulet,
  • Marine Veleur,
  • Julie Chédeau,
  • Jérôme Lefeuvre and ,
  • Gérald Fain,
  • Antoine Paul,
  • Mihaela Alexandru and
  • Jérôme Nevoux
  • + 3 authors+ 0 author

9 January 2025

Objectives: Hearing aids (HAs) have been used for standard high-frequency hearing loss and tinnitus, but their effects on speech intelligibility in noise (SIN) in people with normal hearing, including hidden hearing loss (HHL), have been little explo...

(This article belongs to the Section Otolaryngology)
  • Article
  • Open Access
5 Citations
2,862 Views
10 Pages

The Effects of Utilizing Cartilage Conduction Hearing Aids among Patients with Conductive Hearing Loss

  • Takuya Kakuki,
  • Ryo Miyata,
  • Yurie Yoshida,
  • Aya Kaizaki and ,
  • Ayami Kimura,
  • Kaede Kurashima,
  • Rui Kuwata and
  • Kenichi Takano
  • + 3 authors+ 0 author

The cartilage-conduction hearing aid (CC-HA) is a new hearing device that is suitable for use in patients with conductive hearing loss. It has been 5 years since the introduction of the CC-HA. Although the number of users has increased, the CC-HA is...

(This article belongs to the Special Issue Bone and Cartilage Conduction—Volume II)
  • Article
  • Open Access
6 Citations
3,329 Views
13 Pages

14 March 2023

In patients with bilateral asymmetrical hearing loss (AHL), where only one hearing aid is available, it is difficult to decide which ear to amplify. The aim of this study was to evaluate the outcomes of hearing aid use for AHL patients fitted with a...

(This article belongs to the Special Issue Hearing Disorders: Diagnosis, Management, and Future Opportunities: 2nd Edition)
  • Article
  • Open Access
2,598 Views
12 Pages

Exploring the Relationship between Persons with Hearing Loss/Deafness and Their Hearing Dogs

  • Carlie J. Driscoll,
  • Jessica Hill,
  • Anna Torre and
  • Nancy Pachana

22 May 2024

The reported positive outcomes of animal-assisted services have led to an emerging interest in many different aspects of human–animal interactions. The influence of an assistance animal is thought to encompass several psychosocial domains in th...

(This article belongs to the Section Human-Animal Interactions, Animal Behaviour and Emotion)
  • Review
  • Open Access
33 Citations
7,934 Views
13 Pages

Activation of KCNQ4 as a Therapeutic Strategy to Treat Hearing Loss

  • John Hoon Rim,
  • Jae Young Choi,
  • Jinsei Jung and
  • Heon Yung Gee

Potassium voltage-gated channel subfamily q member 4 (KCNQ4) is a voltage-gated potassium channel that plays essential roles in maintaining ion homeostasis and regulating hair cell membrane potential. Reduction of the activity of the KCNQ4 channel ow...

(This article belongs to the Special Issue Molecular Mechanisms of Sensorineural Hearing Loss and Development of Inner Ear Therapeutics)
  • Review
  • Open Access
658 Views
21 Pages

1 September 2026

Background/Objectives: Universal newborn hearing screening (UNHS) has significantly improved early detection of congenital hearing loss; however, discrepancies persist between prevalence at birth and latter childhood. These findings suggest the prese...

(This article belongs to the Section Pediatric Otolaryngology)
  • Article
  • Open Access
5 Citations
3,354 Views
11 Pages

Comparison of Active Bone Conduction Hearing Implant Systems in Unilateral and Bilateral Conductive or Mixed Hearing Loss

  • Andrea Canale,
  • Anastasia Urbanelli,
  • Maria Gragnano,
  • Valerio Bordino and
  • Andrea Albera

Background: To assess and compare binaural benefits and subjective satisfaction of active bone conduction implant (BCI) in patients with bilateral conductive or mixed hearing loss fitted with bilateral BCI and patients with monaural conductive hearin...

(This article belongs to the Section Sensory and Motor Neuroscience)
  • Review
  • Open Access
8 Citations
6,188 Views
11 Pages

Hearing Loss and Blood Coagulation Disorders: A Review

  • Virginia Corazzi,
  • Andrea Migliorelli,
  • Chiara Bianchini,
  • Stefano Pelucchi and
  • Andrea Ciorba

A relationship between microvascular disorders and sensorineural hearing loss (SNHL) has been widely proposed. The vascular hypothesis, theorized for the onset of sudden SNHL (SSNHL), is among the most acknowledged: a localized acute cochlear damage,...

  • Review
  • Open Access
3,089 Views
7 Pages

Management Options in the Sudden Hearing Loss of a Diabetic Patient

  • Andreea Rusescu,
  • Viorel Zainea,
  • Oana Ruxandra Iana,
  • Irina Ioniță and ,
  • George Traian Alexandru Burcea-Dragomiroiu,
  • Dragos Cristian Ștefănescu,
  • Dumitru Cristinel Badiu,
  • Florentina Gherghiceanu,
  • Cătălina Pietrosanu and
  • Mura Hainarosie
  • + 7 authors+ 2 authors

The aim of our paper is to highlight the main therapeutic principles and the management options in the case of a diabetic patient who has had a sudden hearing loss. Mainly, the aim is to underline the sudden hearing loss treatment adjustment of the d...

  • Article
  • Open Access
1,372 Views
19 Pages

Determinants of Speech Perception Outcomes After Hearing Aid Fitting in Conductive and Sensorineural Hearing Loss: A Prospective Longitudinal Observational Study

  • Akmaral Izbassarova,
  • Assel Imangaliyeva,
  • Vigen Bakhshinyan,
  • Rimma Suatbayeva and ,
  • Zilola Mavlyanova,
  • Assel Izbassarova,
  • Murat Auyelbayev,
  • Kanat Kumar and
  • Aizhan Aidaralieva
  • + 4 authors+ 0 author

Background/Objectives: Hearing loss is a leading cause of disability worldwide, with speech perception representing a key functional outcome of auditory rehabilitation. While hearing aids improve audibility, outcomes vary substantially across clinica...

  • Review
  • Open Access
1 Citations
2,435 Views
21 Pages

Mood and Cognitive Disorders Following Hearing Loss: Impact of Hearing Aid Timing

  • Giuseppe Alberti,
  • Sabrina Loteta,
  • Daniele Portelli,
  • Cosimo Galletti and ,
  • Francesco Galletti,
  • Bruno Galletti,
  • Mario Lentini,
  • Salvatore Ronsivalle,
  • Salvatore Maira and
  • Antonino Maniaci
  • + 7 authors+ 2 authors

Background: Hearing loss is one of the most common yet often overlooked sensory deficits worldwide, with consequences extending well beyond auditory function. Mounting evidence highlights the complex interrelationships among hearing loss, cognitive d...

(This article belongs to the Special Issue Emerging Technologies in Audiology: Advancing Assessment, Intervention, and Accessibility)
  • Review
  • Open Access
13 Citations
6,204 Views
17 Pages

20 October 2020

Most adults who acquire hearing loss find it to be a disability that is poorly corrected by current prosthetics. This gap drives current research in cochlear mechanosensory hair cell regeneration and in hearing restoration. Birds and fish can spontan...

(This article belongs to the Section Systems Neuroscience)
  • Article
  • Open Access
7 Citations
3,365 Views
17 Pages

Relationship between Behavioral Infant Speech Perception and Hearing Age for Children with Hearing Loss

  • Kristin M. Uhler,
  • Alexander M. Kaizer,
  • Kerry A. Walker and
  • Phillip M. Gilley

30 September 2021

(1) Background: Research has demonstrated that early intervention for children who are hard-of-hearing (CHH) facilitates improved language development. Early speech perception abilities may impact CHH outcomes and guide future intervention. The objec...

(This article belongs to the Section Otolaryngology)
  • Article
  • Open Access
9 Citations
3,944 Views
16 Pages

Prevalence of Hearing Loss and Perceptions of Hearing Health and Protection among Florida Firefighters

  • Barbara Millet,
  • Hillary A. Snapp,
  • Suhrud M. Rajguru and
  • Natasha Schaefer Solle

Firefighters are exposed to extensive hazardous noise while on the job, both during routine tasks at the station and when responding to calls. However, little is known about firefighters’ occupational noise hazards. This study employed mixed me...

(This article belongs to the Special Issue 2nd Edition: Police Officers, Firefighters and/or Militaries High-Risk Job Occupations: Assessment of the Different Threats and Preventive Measures)
  • Systematic Review
  • Open Access
1 Citations
1,242 Views
14 Pages

Association Between Cardiovascular Risk Factors and Hearing Loss, Including Sudden Sensorineural Hearing Loss: An Umbrella Review of Systematic Reviews and Meta-Analyses

  • Nerea Moreno-Herraiz,
  • Lucimere Bohn,
  • Iris Otero-Luis,
  • Iván Cavero-Redondo and ,
  • Erika Zornoza-González,
  • Ana Escobar-Molina and
  • Alicia Saz-Lara
  • + 2 authors+ 0 author

19 March 2026

Hearing loss is among the most common chronic diseases worldwide, affecting approximately 466 million people. Increasing evidence suggests that several cardiovascular risk factors traditionally associated with cardiovascular disease may be associated...

  • Review
  • Open Access
9 Citations
7,265 Views
8 Pages

23 September 2022

Sjögren’s syndrome is a chronic autoimmune disease characterized by systemic dysfunction of exocrine glands, mainly the salivary and lachrymal glands. Sjögren’s syndrome consists of two forms: primary Sjögren’s syndro...

(This article belongs to the Special Issue Molecular Mechanisms of Sjögren's Syndrome 2.0)
  • Review
  • Open Access
31 Citations
11,852 Views
30 Pages

16 June 2023

Virus infection is one of the most common etiologies of hearing loss. Hearing loss associated with viral infection can be unilateral or bilateral, mild or severe, sudden or progressive, and permanent or recoverable. Many viruses cause hearing loss in...

(This article belongs to the Section Human Virology and Viral Diseases)
  • Article
  • Open Access
8 Citations
3,618 Views
8 Pages

Association of Fabry Disease with Hearing Loss, Tinnitus, and Sudden Hearing Loss: A Nationwide Population-Based Study

  • Yen-Fu Cheng,
  • Sudha Xirasagar,
  • Chin-Shyan Chen,
  • Dau-Ming Niu and
  • Herng-Ching Lin

13 December 2022

Hearing loss and the related otologic manifestations are receiving increased scrutiny as significant causes of morbidity in Fabry disease. However, the relative risks of auditory deficits among patients with Fabry disease relative to the general popu...

(This article belongs to the Section Otolaryngology)
  • Article
  • Open Access
3 Citations
3,471 Views
13 Pages

Novel OTOG Variants and Clinical Features of Hearing Loss in a Large Japanese Cohort

  • Yasuhiro Arai,
  • Shin-ya Nishio,
  • Shinichi Goto,
  • Yumiko Kobayashi and ,
  • Yohei Honkura,
  • Akira Ganaha,
  • Kotaro Ishikawa,
  • Shin-ichiro Oka,
  • Hiroshi Futagawa and
  • Shin-ichi Usami
  • + 15 authors+ 10 authors

7 January 2025

Background/Objectives: The OTOG gene is responsible for autosomal recessive non-syndromic sensorineural hearing loss and is assigned as DFNB18B. To date, 44 causative OTOG variants have been reported to cause non-syndromic hearing loss. However, the...

(This article belongs to the Section Human Genomics and Genetic Diseases)
  • Article
  • Open Access
11 Citations
2,548 Views
12 Pages

Exploring the Hearing Improvement and Parental Stress in Children with Hearing Loss Using Hearing Aids or Cochlear Implants

  • Daniele Portelli,
  • Clara Lombardo,
  • Sabrina Loteta,
  • Cosimo Galletti and ,
  • Carmela Azielli,
  • Francesco Ciodaro,
  • Carmela Mento,
  • M’Hammed Aguennouz,
  • Gabriella Di Rosa and
  • Giuseppe Alberti
  • + 6 authors+ 1 author

24 December 2024

Objectives: This study aims to describe the stress levels experienced by parents of children with hearing loss who use conventional hearing aids or cochlear implants, and to assess the correlation between parental stress and the auditory skills acqui...

(This article belongs to the Section Otolaryngology)
  • Review
  • Open Access
2 Citations
4,031 Views
15 Pages

Impacts and Identification of Hearing Aid Refurbishing Programs for People with Hearing Loss: A Scoping Review

  • Mathieu Hotton,
  • Virginie Prud’Homme,
  • Léa Richard,
  • Laurie Cormier and ,
  • Katherine Simoneau,
  • Mathilde Lefebvre-Demers,
  • Claude Vincent and
  • Normand Boucher
  • + 3 authors+ 0 author

This article consists of a scoping review completed to describe the impacts of refurbished hearing aids (HAs) for people with hearing loss, and to identify existing HA refurbishing programs around the world. In this review, JBI methodological guidanc...

  • Review
  • Open Access
71 Citations
15,755 Views
11 Pages

Newborn and Infant Hearing Screening Facing Globally Growing Numbers of People Suffering from Disabling Hearing Loss

  • Katrin Neumann,
  • Shelly Chadha,
  • George Tavartkiladze,
  • Xingkuan Bu and
  • Karl R. White

Recent prevalence estimates indicate that in 2015 almost half a billion people—about 6.8% of the world’s population—had disabling hearing loss and that prevalence numbers will further increase. The World Health Organization (WHO) cu...

(This article belongs to the Special Issue Newborn Hearing Screening)
  • Article
  • Open Access
3,241 Views
11 Pages

Underestimated Subsequent Sensorineural Hearing Loss after Septicemia

  • Chun-Gu Cheng,
  • Yu-Hsuan Chen,
  • Yin-Han Chang,
  • Hui-Chen Lin and ,
  • Pi-Wei Chin,
  • Yen-Yue Lin,
  • Ming-Chi Yung and
  • Chun-An Cheng
  • + 3 authors+ 0 author

26 October 2023

Background and Objectives: Hearing loss after septicemia has been found in mice; the long-term risk increased 50-fold in young adults in a previous study. Hearing loss after septicemia has not received much attention. The aim of this study was to ass...

(This article belongs to the Topic Public Health and Healthcare in the Context of Big Data)
  • Review
  • Open Access
72 Citations
11,571 Views
17 Pages

Role of Oxidative Stress in Sensorineural Hearing Loss

  • Masato Teraoka,
  • Naohito Hato,
  • Haruhiko Inufusa and
  • Fukka You

Hearing is essential for communication, and its loss can cause a serious disruption to one’s social life. Hearing loss is also recognized as a major risk factor for dementia; therefore, addressing hearing loss is a pressing global issue. Sensor...

(This article belongs to the Special Issue Oxidative Stress and Antioxidants in Human Diseases)
  • Review
  • Open Access
9 Citations
7,004 Views
11 Pages

Congenital Cytomegalovirus-Related Hearing Loss

  • Nicoleta Gana,
  • Iulia Huluță,
  • Mihai-Ștefan Cătănescu,
  • Livia-Mihaela Apostol and ,
  • Florina Mihaela Nedelea,
  • Romina-Marina Sima,
  • Radu Botezatu,
  • Anca Maria Panaitescu and
  • Nicolae Gică
  • + 4 authors+ 0 author

16 June 2024

Congenital hearing loss is a significant global health concern that affects millions of newborns and infants worldwide, posing substantial challenges for affected individuals, their families, and healthcare systems. This condition, present at birth,...

(This article belongs to the Special Issue Hearing Loss: Causes, Symptoms, Diagnosis, and Treatment)
  • Article
  • Open Access
14 Citations
7,943 Views
13 Pages

Hearing and Hearing Loss Progression in Patients with GJB2 Gene Mutations: A Long-Term Follow-Up

  • Aki Sakata,
  • Akinori Kashio,
  • Misaki Koyama,
  • Shinji Urata and ,
  • Hajime Koyama and
  • Tatsuya Yamasoba
  • + 1 author+ 0 author

25 November 2023

We aimed to investigate whether the degree of hearing loss with GJB2 mutations could be predicted by distinguishing between truncating and non-truncating mutations and whether the genotype could predict the hearing loss level. Additionally, we examin...

(This article belongs to the Special Issue Genetic Variations in Human Diseases)
  • Article
  • Open Access
50 Citations
11,289 Views
14 Pages

Action to prevent noise-induced hearing loss is necessary, especially because many causes of permanent hearing loss are preventable. The aim of this study is to identify and raise awareness of the effect of loud sounds on hearing and effective ways t...

(This article belongs to the Special Issue Environmental Exposures and Hearing Loss)
  • Review
  • Open Access
1 Citations
2,143 Views
10 Pages

Hearing Loss and Chiari Malformation Type I: A Scoping Review

  • Andrea Migliorelli,
  • Marianna Manuelli,
  • Chiara Bianchini,
  • Francesco Stomeo and ,
  • Stefano Pelucchi,
  • Silvia Palma and
  • Andrea Ciorba
  • + 2 authors+ 0 author

25 September 2025

Background/Objectives: Chiari malformation (CM) type I is an uncommon condition that can be associated with a variety of neurological and otoneurological symptoms, including sensorineural hearing loss. The aim of this paper is to analyze the associat...

  • Article
  • Open Access
4 Citations
3,750 Views
10 Pages

31 October 2024

Introduction: Universal newborn hearing screening has been successfully implemented in many places around the world, and it is recommended that cases with risk factors for hearing loss be followed-up regardless of hearing screening results. However,...

(This article belongs to the Section Pediatric Neurology & Neurodevelopmental Disorders)
  • Review
  • Open Access
1,344 Views
14 Pages

Hearing Loss and Dementia: Risk Factor, Early Marker, or Both?

  • Ljiljana Cvorovic,
  • Ana Jotic,
  • Bojana Bukurov,
  • Saša Jakovljevic and ,
  • Simona Aleksic and
  • Katarina Jovanovic
  • + 1 author+ 0 author

Background/Objectives: Hearing loss and dementia are highly prevalent conditions in older adults and represent a growing public health challenge. Over the past decade, a substantial body of epidemiological evidence has demonstrated a consistent assoc...

(This article belongs to the Special Issue Otorhinolaryngology in Modern Healthcare: Advances, Challenges, and Perspectives)
  • Article
  • Open Access
1 Citations
1,913 Views
17 Pages

Background/Objective: Self-perceived hearing handicap (SPHH) reflects functional consequences of hearing loss beyond audiometric measures. Clarifying its relationship with audiometric severity and demographic factors is important for understanding ag...

(This article belongs to the Special Issue Hearing Loss: Causes, Symptoms, Diagnosis, and Treatment—Volume II)
  • Review
  • Open Access
79 Citations
11,976 Views
25 Pages

Association of Nutritional Factors with Hearing Loss

  • Su Young Jung,
  • Sang Hoon Kim and
  • Seung Geun Yeo

1 February 2019

Hearing loss (HL) is a major public health problem. Nutritional factors can affect a variety of diseases, such as HL, in humans. Thus far, several studies have evaluated the association between nutrition and hearing. These studies found that the inci...

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