Background/Objectives: Growth failure is a common complication in children with congenital heart disease (CHD), yet its underlying mechanisms and consequences remain incompletely understood. This review aims to provide a comprehensive overview of gro...
Although prior research acknowledges that small and medium-sized enterprises (SMEs) can turn failures into growth opportunities, the mechanisms through which failure analysis contributes to such growth remain underexplored. Grounded in organizational...
The growth stress induced by thermally grown oxide (TGO) is one of the main reasons for the failure of thermal barrier coatings (TBCs). In this study, the failure behavior of TBCs was examined based on different growth modes of TGO. A TBC thermo-mech...
Heart failure (HF) remains a major cause of morbidity and mortality worldwide. While standard treatments primarily target neurohormonal pathways, emerging evidence highlights the significant role of hormonal deficiencies, such as impaired growth horm...
Background/Objectives: Child growth failure is a manifestation of chronic malnutrition expressed in stunting, wasting, and underweight in children. This study aimed to analyze global trends in child growth failure disease burden and mortality across...
Objectives: To identify factors associated with postnatal growth failure (PGF) in very-low-birth-weight (VLBW) infants and to develop a model for the early identification of neonates at risk. Methods: This retrospective cohort study included VLBW inf...
(1) Introduction: Current evidence on managing infants under six months with growth failure or other nutrition-related risk is sparse and low quality. This review aims to inform research priorities to fill this evidence gap, focusing on breastfeeding...
The unexpected failures of structural materials in very high cycle fatigue (VHCF) regime have been a critical issue in modern engineering design. In this study, the VHCF property of a Cr-Ni-W gear steel was experimentally investigated under axial loa...
Ras homologue enriched in brain 1 (Rheb1) plays an important role in a variety of cellular processes. In this study, we investigate the role of Rheb1 in the post-natal heart. We found that deletion of the gene responsible for production of Rheb1 from...
Background and Objectives: Obesity, heart failure (HF), and atherosclerosis have common pathways, including chronic inflammation, immune cells activation, and metabolic disturbances. These pathways often coexist and overlap, increasing cardiometaboli...
Accurate prediction of postnatal growth failure (PGF) can be beneficial for early intervention and prevention. We aimed to develop a machine learning model to predict PGF at discharge among very low birth weight (VLBW) infants using extreme gradient...
Graft failure (GF) remains a significant limitation to improve long-term outcomes in renal transplant recipients (RTR). Urinary epidermal growth factor (uEGF) is involved in kidney tissue integrity, with a reduction of its urinary excretion being ass...
Complex genetic syndromes represent a diagnostic challenge due to their diverse phenotypic presentations, which often evolve over time and may not be fully evident at birth. Disorders of sex development (DSD) comprise congenital conditions with disco...
Recurrent implantation failure (RIF) remains a challenging clinical problem. Growth hormone (GH) co-treatment has been explored as an adjunct in poor responders and RIF patients, with inconsistent evidence of benefit. This prospective cohort study as...
Chronic kidney disease (CKD) is a significant challenge for pediatric endocrinologists, as children with CKD may present a variety of endocrine complications. Growth failure is common in CKD, and its severity is correlated with the degree of renal in...
The coronavirus disease (COVID-19) outbreak has prompted various industries to embark on digital transformation efforts, with software playing a critical role. Ensuring the reliability of software is of the utmost importance given its widespread use...
Background/Objectives: Preterm infants often require increased caloric intake to maintain appropriate growth while in the neonatal intensive care unit (NICU). Emerging evidence suggests that alterations of the gut microbiome may play a role in infant...
Background/Objectives: Greater than 50% of surviving very preterm infants are affected by postnatal growth failure and are at high risk of associated development of bronchopulmonary dysplasia (BPD). Given the influence of enteral feeding on growth fa...
Necrotizing enterocolitis (NEC), the first cause of short bowel syndrome (SBS) in the neonate, is a serious neonatal gastrointestinal disease with an incidence of up to 11% in preterm newborns less than 1500 g of birth weight. The rate of severe NEC...
Although the survival rate of preterm infants has improved over the years, growth failure and associated impaired neurodevelopmental outcome remains a significant morbidity. Optimal nutrition plays an important role in achieving adequate postnatal gr...
Heart failure (HF) is a growing public health burden, with high prevalence and mortality rates. In contrast to ischemic heart failure (IHF), the diagnosis of non-ischemic heart failure (NIHF) is established in the absence of coronary artery disease....
The most common causes of short stature (SS) in children are familial short stature (FSS) and idiopathic short stature (ISS). Recently, growth plate dysfunction has been recognized as the genetic cause of FSS or ISS. The aim of this study was to inve...
Navigable waterways play a vital role in the efficient transportation of millions of tons of cargo annually. Inland traffic must pass through a lock, which consists of miter gates. Failures and closures of these gates can significantly disrupt waterb...
Aim: To analyze different methods to assess postnatal growth in a cohort of very premature infants (VPI) in a clinical setting and identify potential early markers of growth failure. Methods: Study of growth determinants in VPI (≤32 weeks) during...
This paper reviews the role of void nucleation, growth, and coalescence on the spall failure process in light metals. Based on the review of the open literature, the preponderance of evidence show that void nucleation, growth, and coalescence are pre...
Growth kinetics and the irreversible deformation of thermally growth oxide (TGO) critically affect the delamination and cracking at the interface of thermal barrier coatings (TBCs). In this study, TGO dynamic growth during furnace cycles is simulated...
This study presents a two-dimensional ordinary state-based peridynamic (OSB PD) modeling of mode-I delamination growth in a double cantilever composite beam (DCB) test using revised energy-based failure criteria. The two-dimensional OSB PD composite...
Over the last few decades, there has been an ongoing debate over both the optimal feeding mode for very premature neonates (VPN) as well as what their optimal growth should be. Despite the American Academy of Pediatric declaring since 1997 that the g...
Due to the complex geometry and various cyclic loads, aeroengine components are often in a multiaxial complex stress state during service. Multiaxial fatigue is a major cause of many air accidents. It is of great significance to study the fatigue fai...
Background: In daily practice, there are problems with adequately diagnosing the cause of dyspnea in patients with heart failure with preserved and mildly reduced ejection fractions (HFpEF and HFmrEF). This study aimed to assess the usefulness of lun...
Axial loading tests with stress ratios R of −1, 0 and 0.3 were performed to examine the fatigue failure behavior of a carburized Cr-Ni steel in the long-life regime from 104 to 108 cycles. Results show that this steel represents continuously descendi...
Crack-growth behavior in yttria-stabilized zirconia-based thermal barrier coatings (TBCs) is investigated through a cyclic thermal fatigue (CTF) test to understand TBCs’ failure mechanisms. Initial cracks were introduced on the coatings’...
Despite being designed considering infinite fatigue-life, failures of motor crankshafts forged from DIN 34CrNiMo6 steels have been reported in Brazilian power plants. As such, the present work aims to discuss the failure of a crankshaft within this c...
A strain isolation pad is a critical connection mechanism that enables deformation coordination between the rigid thermal insulation tile and the primary structure in the thermal protection system of a reusable hypersonic vehicle. An experimental inv...
Vascular endothelial growth factor (VEGF) is a well-known angiogenic factor that plays a critical role in various physiological and pathological processes. VEGF also contributes to the process of embryo implantation by enhancing embryo development, i...
Failure to thrive (FTT) is an abnormal growth pattern determined by inadequate nutrition. It is a common problem in children, representing 5% to 10% of patients seen in an outpatient setting. Many definitions have been proposed based on anthropometri...
Based on the crack propagation rate test of LY12CZ aluminum alloy flat plate, the distribution characteristics of Paris formula parameters were characterized by the three-parameter logarithmic normal distribution, and a LY12CZ random crack propagatio...
Very preterm infants (VPI, born at or before 32 weeks of gestation) are at risk of adverse health outcomes, from which they might be partially protected with appropriate postnatal nutrition and growth. Metabolic processes or biochemical markers assoc...
Porcine circovirus type 3 (PCV3) is a nonenveloped virus of the Circoviridae family. This virus has been identified in pigs of different ages and pigs with several clinical manifestations of the disease or even in apparently healthy pigs. While PCV3...
Testing and the estimation methods for predicting the life of crack initiation and crack growth for P92 steel using a circular sharp notched round bar specimen (CNS) under strain-controlled creep and fatigue conditions have been reported previously....
Male infertility affects half of infertile couples and, currently, a relevant percentage of cases of male infertility is considered as idiopathic. Although the male contribution to human fertilization has traditionally been restricted to sperm DNA, c...
The relationship between tearing energy and crack growth rates in elastomers is typically divided into three regions—slow crack growth, fast crack growth, and a transitional region—each described by separate power law relationships, requi...
Inflammatory bowel diseases (IBD) are gastrointestinal tract pathologies of unknown etiology; they have an alternating trend, with active and silent phases. IBD are classified in two main forms: ulcerative colitis (UC) and Crohn’s disease (CD)....
Background: This cross-sectional study aimed to assess growth, body weight, and bone mineralization and to identify predictors of metabolic bone disease (MBD) in children with chronic intestinal failure (CIF) on long-term parenteral nutrition (LPN)....
Rock damage caused by its microcrack growth has a great influence on the deformation and strength properties of rock under compressive loading. Considering the interaction of wing cracks and the additional stress caused by rock bridge damage, a new c...
Background: Vascular Endothelial Growth Factor (VEGF) is a key regulator in angiogenesis and contributes to a successful implantation. The current study has the following objective: to perform genotyping and haplotyping analysis to confirm whether th...
Hepatocyte growth factor (HGF) is an endogenously expressed bioactive substance that has a strong anti-apoptotic effect. In this study, we biochemically and histologically characterized the effects of rh-HGF on in vitro human hepatocyte injury and mo...
Rapid progress in the performance of organic devices has increased the demand for advances in the technology of thin-film permeation barriers and understanding the failure mechanisms of these material systems. Herein, we report the extensive study of...
Cardiac hepatopathy refers to acute or chronic liver damage caused by cardiac dysfunction in the absence of any other possible causative reasons of liver injury. There is a large number of evidence of the fact that cardiac hepatopathy is associated w...
Heart failure (HF), particularly of an ischemic etiology, is steadily increasing worldwide. Non-anemic iron deficiency (ID) is highly prevalent among HF patients, and it has been related to worse outcomes. Growth differentiation factor 15 (GDF15) has...
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