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1,628 Results Found

  • Article
  • Open Access
729 Views
19 Pages

22 October 2025

Diabetes is a metabolic disorder characterized by persistent hyperglycemia, with its incidence steadily rising worldwide. Blood glucose monitoring is a core measure in diabetes management, and continuous glucose monitoring provides more comprehensive...

  • Article
  • Open Access
34 Citations
6,469 Views
15 Pages

Developing an Individual Glucose Prediction Model Using Recurrent Neural Network

  • Dae-Yeon Kim,
  • Dong-Sik Choi,
  • Jaeyun Kim,
  • Sung Wan Chun,
  • Hyo-Wook Gil,
  • Nam-Jun Cho,
  • Ah Reum Kang and
  • Jiyoung Woo

12 November 2020

In this study, we propose a personalized glucose prediction model using deep learning for hospitalized patients who experience Type-2 diabetes. We aim for our model to assist the medical personnel who check the blood glucose and control the amount of...

  • Article
  • Open Access
96 Citations
8,790 Views
16 Pages

6 May 2020

In recent years, with increasing social pressure and irregular schedules, many people have developed unhealthy eating habits, which has resulted in an increasing number of patients with diabetes, a disease that cannot be cured under the current medic...

  • Article
  • Open Access
46 Citations
8,970 Views
17 Pages

13 July 2020

Accurate estimations for the near future levels of blood glucose are crucial for Type 1 Diabetes Mellitus (T1DM) patients in order to be able to react on time and avoid hypo and hyper-glycemic episodes. Accurate predictions for blood glucose are the...

  • Article
  • Open Access
20 Citations
4,814 Views
22 Pages

In this paper, we present an architecture of a personalized glucose monitoring system (PGMS). PGMS consists of both invasive and non-invasive sensors on a single device. Initially, blood glucose is measured invasively and non-invasively, to train the...

  • Proceeding Paper
  • Open Access
2 Citations
4,482 Views
8 Pages

26 November 2024

Diabetes mellitus is a chronic metabolic disorder characterized by the dysregulation of blood glucose, which can lead to a range of serious health complications if not properly managed. Continuous glucose monitoring (CGM) is a cutting-edge technology...

  • Review
  • Open Access
2 Citations
4,115 Views
20 Pages

Blood Glucose Prediction from Nutrition Analytics in Type 1 Diabetes: A Review

  • Nicole Lubasinski,
  • Hood Thabit,
  • Paul W. Nutter and
  • Simon Harper

10 July 2024

Introduction: Type 1 Diabetes (T1D) affects over 9 million worldwide and necessitates meticulous self-management for blood glucose (BG) control. Utilizing BG prediction technology allows for increased BG control and a reduction in the diabetes burden...

  • Article
  • Open Access
1 Citations
2,133 Views
17 Pages

Individualized Prediction of Blood Glucose Outcomes Using Compositional Data Analysis

  • Alvis Cabrera,
  • Ernesto Estremera,
  • Aleix Beneyto,
  • Lyvia Biagi,
  • Iván Contreras,
  • Josep Antoni Martín-Fernández and
  • Josep Vehí

2 November 2023

This paper presents an individualized multiple linear regression model based on compositional data where we predict the mean and coefficient of variation of blood glucose in individuals with type 1 diabetes for the long-term (2 and 4 h). From these p...

  • Article
  • Open Access
13 Citations
5,035 Views
18 Pages

In this paper we investigate the effect of two preprocessing techniques, data imputation and smoothing, in the prediction of blood glucose level in type 1 diabetes patients, using a novel deep learning model called Transformer. We train three models:...

  • Article
  • Open Access
11 Citations
4,554 Views
12 Pages

Machine Learning and Deep Learning Models for Nocturnal High- and Low-Glucose Prediction in Adults with Type 1 Diabetes

  • Roman M. Kozinetz,
  • Vladimir B. Berikov,
  • Julia F. Semenova and
  • Vadim V. Klimontov

Glucose management at night is a major challenge for people with type 1 diabetes (T1D), especially for those managed with multiple daily injections (MDIs). In this study, we developed machine learning (ML) and deep learning (DL) models to predict noc...

  • Article
  • Open Access
29 Citations
6,251 Views
19 Pages

Diabetes Mellitus, a metabolic disease, causes the body to lose control over blood glucose regulation. With recent advances in self-monitoring systems, a patient can access their personalized glycemic profile and may utilize it for efficient predicti...

  • Article
  • Open Access
1,894 Views
27 Pages

Incorporating Uncertainty Estimation and Interpretability in Personalized Glucose Prediction Using the Temporal Fusion Transformer

  • Antonio J. Rodriguez-Almeida,
  • Carmelo Betancort,
  • Ana M. Wägner,
  • Gustavo M. Callico,
  • Himar Fabelo and
  • on behalf of the WARIFA Consortium

26 July 2025

More than 14% of the world’s population suffered from diabetes mellitus in 2022. This metabolic condition is defined by increased blood glucose concentrations. Among the different types of diabetes, type 1 diabetes, caused by a lack of insulin...

  • Article
  • Open Access
1 Citations
2,608 Views
11 Pages

30 October 2024

Background: Machine learning offers new options for glucose prediction and real-time glucose management. The aim of this study was to develop a machine learning-based algorithm that takes into account glucose dynamics patterns for predicting nocturna...

  • Article
  • Open Access
26 Citations
4,558 Views
27 Pages

26 October 2021

This article proposes two ensemble neural network-based models for blood glucose prediction at three different prediction horizons—30, 60, and 120 min—and compares their performance with ten recently proposed neural networks. The twelve models’ perfo...

  • Article
  • Open Access
6 Citations
3,288 Views
18 Pages

30 June 2021

Background and Objectives: The daily lifestyle management of diabetes requires accurate predictions of the blood glucose level between meals. The objective of this study was to improve the accuracy achieved by previous work, especially on the mid-ter...

  • Article
  • Open Access
11 Citations
2,841 Views
26 Pages

4 May 2021

Accurate glucose prediction along a long-enough time horizon is a key component for technology to improve type 1 diabetes treatment. Subjects with diabetes might benefit from supervision and control systems that accurately predict risks and trigger c...

  • Proceeding Paper
  • Open Access

7 November 2025

Wearable sensors offer a promising platform for non-invasive glucose monitoring by indirectly predicting glucose levels from physiological signals. However, machine learning models trained on such data often suffer degraded performance when applied t...

  • Article
  • Open Access
27 Citations
3,785 Views
15 Pages

Prediction of Glucose Intolerance in Early Postpartum in Women with Gestational Diabetes Mellitus Based on the 2013 WHO Criteria

  • Katrien Benhalima,
  • Paul Van Crombrugge,
  • Carolien Moyson,
  • Johan Verhaeghe,
  • Sofie Vandeginste,
  • Hilde Verlaenen,
  • Chris Vercammen,
  • Toon Maes,
  • Els Dufraimont and
  • Christophe De Block
  • + 9 authors

19 March 2019

Predictors for glucose intolerance postpartum were evaluated in women with gestational diabetes mellitus (GDM) based on the 2013 World Health Organization (WHO) criteria. 1841 women were tested for GDM in a prospective cohort study. A postpartum 75g...

  • Article
  • Open Access
15 Citations
2,652 Views
23 Pages

This paper proposes an RG hyperparameter optimization approach, based on a sequential use of random search (R) and grid search (G), for improving the blood glucose level prediction of boosting ensemble learning models. An indirect prediction of blood...

  • Article
  • Open Access
20 Citations
3,308 Views
15 Pages

Prediction of Glucose Concentration in Children with Type 1 Diabetes Using Neural Networks: An Edge Computing Application

  • Federico D’Antoni,
  • Lorenzo Petrosino,
  • Fabiola Sgarro,
  • Antonio Pagano,
  • Luca Vollero,
  • Vincenzo Piemonte and
  • Mario Merone

Background: Type 1 Diabetes Mellitus (T1D) is an autoimmune disease that can cause serious complications that can be avoided by preventing the glycemic levels from exceeding the physiological range. Straightforwardly, many data-driven models were dev...

  • Article
  • Open Access
1 Citations
1,497 Views
12 Pages

Background/Objectives: Accurate blood glucose forecasting is critical for closed-loop insulin delivery systems to support effective disease management in people with type 1 diabetes (T1D). While long short-term memory (LSTM) neural networks have show...

  • Article
  • Open Access
1 Citations
984 Views
25 Pages

26 November 2024

Continuous glucose monitoring data have strong time variability as well as complex non-stationarity and nonlinearity. The existing blood glucose concentration prediction models often overlook the impacts of residual components after multi-scale decom...

  • Article
  • Open Access
6 Citations
2,631 Views
17 Pages

Assessment of Seasonal Stochastic Local Models for Glucose Prediction without Meal Size Information under Free-Living Conditions

  • Francesco Prendin,
  • José-Luis Díez,
  • Simone Del Favero,
  • Giovanni Sparacino,
  • Andrea Facchinetti and
  • Jorge Bondia

10 November 2022

Accurate blood glucose (BG) forecasting is key in diabetes management, as it allows preventive actions to mitigate harmful hypoglycemic/hyperglycemic episodes. Considering the encouraging results obtained by seasonal stochastic models in proof-of-con...

  • Article
  • Open Access
1 Citations
3,377 Views
14 Pages

Utilizing the Glucose and Insulin Response Shape of an Oral Glucose Tolerance Test to Predict Dysglycemia in Children with Overweight and Obesity, Ages 8–18 Years

  • Timothy J. Renier,
  • Htun Ja Mai,
  • Zheshi Zheng,
  • Mary Ellen Vajravelu,
  • Emily Hirschfeld,
  • Diane Gilbert-Diamond,
  • Joyce M. Lee and
  • Jennifer L. Meijer

Common dysglycemia measurements including fasting plasma glucose (FPG), oral glucose tolerance test (OGTT)-derived 2 h plasma glucose, and hemoglobin A1c (HbA1c) have limitations for children. Dynamic OGTT glucose and insulin responses may better ref...

  • Article
  • Open Access
5 Citations
3,088 Views
19 Pages

Predicting Blood Glucose Concentration after Short-Acting Insulin Injection Using Discontinuous Injection Records

  • Baoyu Tang,
  • Yuyu Yuan,
  • Jincui Yang,
  • Lirong Qiu,
  • Shasha Zhang and
  • Jinsheng Shi

3 November 2022

Diabetes is an increasingly common disease that poses an immense challenge to public health. Hyperglycemia is also a common complication in clinical patients in the intensive care unit, increasing the rate of infection and mortality. The accurate and...

  • Article
  • Open Access
7 Citations
4,160 Views
26 Pages

Enhanced Diabetes Detection and Blood Glucose Prediction Using TinyML-Integrated E-Nose and Breath Analysis: A Novel Approach Combining Synthetic and Real-World Data

  • Alberto Gudiño-Ochoa,
  • Julio Alberto García-Rodríguez,
  • Jorge Ivan Cuevas-Chávez,
  • Raquel Ochoa-Ornelas,
  • Antonio Navarrete-Guzmán,
  • Carlos Vidrios-Serrano and
  • Daniel Alejandro Sánchez-Arias

Diabetes mellitus, a chronic condition affecting millions worldwide, necessitates continuous monitoring of blood glucose level (BGL). The increasing prevalence of diabetes has driven the development of non-invasive methods, such as electronic noses (...

  • Article
  • Open Access
4 Citations
2,471 Views
21 Pages

A Multi-Agent Approach Used to Predict Long-Term Glucose Oscillation in Individuals with Type 1 Diabetes

  • João Paulo Aragão Pereira,
  • Anarosa Alves Franco Brandão,
  • Joyce da Silva Bevilacqua and
  • Maria Lucia Cardillo Côrrea-Giannella

26 September 2022

The glucose–insulin regulatory system and its glucose oscillations is a recurring theme in the literature because of its impact on human lives, mostly the ones affected by diabetes mellitus. Several approaches have been proposed, from mathemati...

  • Article
  • Open Access
9 Citations
4,461 Views
29 Pages

4 August 2021

Diabetes is a chronic disease caused by the inability of the pancreas to produce insulin or problems in the body to use it efficiently. It is one of the fastest growing health challenges affecting more than 400 million people worldwide, according to...

  • Review
  • Open Access
537 Views
18 Pages

The global effort to manage diabetes effectively is driving continuous innovation in glucose monitoring devices. While current systems have improved patient care, persistent challenges with sensor stability and invasiveness highlight the need for adv...

  • Article
  • Open Access
61 Citations
8,280 Views
14 Pages

Utility of Big Data in Predicting Short-Term Blood Glucose Levels in Type 1 Diabetes Mellitus Through Machine Learning Techniques

  • Ignacio Rodríguez-Rodríguez,
  • Ioannis Chatzigiannakis,
  • José-Víctor Rodríguez,
  • Marianna Maranghi,
  • Michele Gentili and
  • Miguel-Ángel Zamora-Izquierdo

16 October 2019

Machine learning techniques combined with wearable electronics can deliver accurate short-term blood glucose level prediction models. These models can learn personalized glucose–insulin dynamics based on the sensor data collected by monitoring...

  • Article
  • Open Access
4 Citations
4,206 Views
18 Pages

A Diabetes Management Information System with Glucose Prediction

  • Cláudio Augusto Silveira Lélis and
  • Renan Motta Goulart

12 December 2018

Diabetes has become a serious health concern. The use and popularization of blood glucose measurement devices have led to a tremendous increase on health for diabetics. Tracking and maintaining traceability between glucose measurements, insulin doses...

  • Article
  • Open Access
258 Views
35 Pages

6 January 2026

Due to the complexity of blood glucose dynamics and the high variability of the physiological structure of diabetic patients, implementing a safe and effective insulin dosage control algorithm to keep the blood glucose of diabetic patients within the...

  • Article
  • Open Access
2 Citations
2,512 Views
17 Pages

A Machine Learning Approach for Enhanced Glucose Prediction in Biosensors

  • António Abreu,
  • Daniela dos Santos Oliveira,
  • Inês Vinagre,
  • Dionisios Cavouras,
  • Joaquim A. Alves,
  • Ana I. Pereira,
  • José Lima and
  • Felismina T. C. Moreira

The detection of glucose is crucial for diagnosing diseases such as diabetes and enables timely medical intervention. In this study, a disposable enzymatic screen-printed electrode electrochemical biosensor enhanced with machine learning (ML) for qua...

  • Comment
  • Open Access
1,514 Views
5 Pages

5 July 2024

The paper “Using Absorption Models for Insulin and Carbohydrates and Deep Leaning to Improve Glucose Level Predictions” (Sensors 2021, 21, 5273) proposes a novel approach to predicting blood glucose levels for people with type 1 diab...

  • Article
  • Open Access
604 Views
20 Pages

Model Predictive Control Using the Improved Hovorka Model for the Regulation of Blood Glucose Levels in Type 1 Diabetes

  • Iqra Shafeeq Mughal,
  • Stefan Koch,
  • Luca Patanè,
  • Martin Steinberger,
  • Riccardo Caponetto and
  • Nebojša Koledin

23 November 2025

Type 1 diabetes is an autoimmune disease that occurs when the immune system unintentionally attacks and damages β cells in the pancreas, reducing the organ’s ability to produce insulin. An artificial pancreas is a technology that uses a pu...

  • Article
  • Open Access
7 Citations
2,370 Views
16 Pages

Blood Glucose Prediction Method Based on Particle Swarm Optimization and Model Fusion

  • He Xu,
  • Shanjun Bao,
  • Xiaoyu Zhang,
  • Shangdong Liu,
  • Wei Jing and
  • Yimu Ji

6 December 2022

Blood glucose stability in diabetic patients determines the degree of health, and changes in blood glucose levels are related to the outcome of diabetic patients. Therefore, accurate monitoring of blood glucose has a crucial role in controlling diabe...

  • Article
  • Open Access
23 Citations
5,594 Views
11 Pages

Unstimulated Parotid Saliva Is a Better Method for Blood Glucose Prediction

  • Yangyang Cui,
  • Hankun Zhang,
  • Jia Zhu,
  • Lu Peng,
  • Zhili Duan,
  • Tian Liu,
  • Jiasheng Zuo,
  • Lu Xing,
  • Zhenhua Liao and
  • Song Wang
  • + 1 author

1 December 2021

Objective: Saliva glucose has been widely used in diagnosing and monitoring diabetes, but the saliva collection method will affect saliva glucose concentration. So, this study aims to identify the ideal saliva collection method. Method: A total amoun...

  • Article
  • Open Access
43 Citations
5,347 Views
12 Pages

Prediction of Insulin Resistance by Modified Triglyceride Glucose Indices in Youth

  • Kyungchul Song,
  • Goeun Park,
  • Hye Sun Lee,
  • Youngha Choi,
  • Jun Suk Oh,
  • Han Saem Choi,
  • Junghwan Suh,
  • Ahreum Kwon,
  • Ho-Seong Kim and
  • Hyun Wook Chae

28 March 2021

The triglyceride glucose (TyG) index, derived from a combination of fasting glucose and triglycerides, has been suggested as a useful marker for insulin resistance (IR), in addition to modified TyG indices that combine obesity parameters. This study...

  • Article
  • Open Access
765 Views
19 Pages

1 October 2025

This research introduces a hybrid framework that integrates stochastic modeling and machine learning for predicting postprandial glucose levels in individuals with Type 1 Diabetes (T1D). The primary aim is to enhance the accuracy of glucose predictio...

  • Article
  • Open Access
2 Citations
3,482 Views
24 Pages

20 September 2024

Postprandial Hyperglycemia (PPHG) persistently threatens patients’ health. Therefore, accurate diabetes prediction is crucial for effective blood glucose management. Most current methods primarily focus on analyzing univariate blood glucose data usin...

  • Article
  • Open Access
36 Citations
7,431 Views
19 Pages

Long-Term Glucose Forecasting Using a Physiological Model and Deconvolution of the Continuous Glucose Monitoring Signal

  • Chengyuan Liu,
  • Josep Vehí,
  • Parizad Avari,
  • Monika Reddy,
  • Nick Oliver,
  • Pantelis Georgiou and
  • Pau Herrero

8 October 2019

(1) Objective: Blood glucose forecasting in type 1 diabetes (T1D) management is a maturing field with numerous algorithms being published and a few of them having reached the commercialisation stage. However, accurate long-term glucose predictions (e...

  • Article
  • Open Access
9 Citations
5,369 Views
14 Pages

20 July 2021

Type 1 diabetes is a chronic disease caused by the inability of the pancreas to produce insulin. Patients suffering type 1 diabetes depend on the appropriate estimation of the units of insulin they have to use in order to keep blood glucose levels in...

  • Article
  • Open Access
19 Citations
3,964 Views
25 Pages

A Federated Learning-Inspired Evolutionary Algorithm: Application to Glucose Prediction

  • Ivanoe De Falco,
  • Antonio Della Cioppa,
  • Tomas Koutny,
  • Martin Ubl,
  • Michal Krcma,
  • Umberto Scafuri and
  • Ernesto Tarantino

8 March 2023

In this paper, we propose an innovative Federated Learning-inspired evolutionary framework. Its main novelty is that this is the first time that an Evolutionary Algorithm is employed on its own to directly perform Federated Learning activity. A furth...

  • Article
  • Open Access
6 Citations
6,603 Views
16 Pages

20 May 2025

Continuous monitoring of glucose levels is important for diabetes management and prevention. While traditional glucose monitoring methods are often invasive and expensive, recent approaches using machine learning (ML) models have explored non-invasiv...

  • Article
  • Open Access
3 Citations
2,709 Views
16 Pages

Predicting Factors for Metabolic Non-Response to a Complex Lifestyle Intervention—A Replication Analysis to a Randomized-Controlled Trial

  • Stefan Kabisch,
  • Nina M. T. Meyer,
  • Caroline Honsek,
  • Margrit Kemper,
  • Christiana Gerbracht,
  • Ayman M. Arafat,
  • Ulrike Dambeck,
  • Martin A. Osterhoff,
  • Martin O. Weickert and
  • Andreas F. H. Pfeiffer

9 November 2022

Background: T2DM heterogeneity affects responsiveness to lifestyle treatment. Beta-cell failure and nonalcoholic fatty liver disease (NAFLD) independently predict T2DM, but NAFLD inconsistently predicts metabolic response to lifestyle intervention. A...

  • Article
  • Open Access
752 Views
12 Pages

Serum Glucose-6-Phosphate Dehydrogenase Activity as a Biomarker for Gastric Cancer Stage Prediction

  • Chang-Hwan Yeom,
  • Jiewon Lee,
  • Keun-Joo Bae,
  • Kangseok Kim,
  • Jongsoon Choi and
  • Myeong-Hun Lim

27 November 2025

Background: Gastric cancer is the fifth most prevalent cancer diagnosed worldwide, and approximately 40% of patients who experience recurrence within five years develop hematogenous metastasis. Given that early prediction of recurrence may improve ov...

  • Article
  • Open Access
729 Views
20 Pages

Prediction of Postprandial Blood Glucose Variability Using Machine Learning in Frequent Insulin Injection Therapy with a Simplified Carbohydrate Counting Model

  • Hiroyuki Tominaga,
  • Masahide Hamaguchi,
  • Youji Hamaguchi,
  • Ren Yashiki,
  • Aki Yamaguchi,
  • Tadaharu Arai,
  • Masahiro Yamazaki,
  • Noriyuki Kitagawa,
  • Yoshitaka Hashimoto and
  • Hiroshi Okada
  • + 1 author

7 December 2025

Background/Objectives: Postprandial glucose variability is a key challenge in diabetes management for patients receiving multiple daily insulin injections (MDI). This study evaluated transformer-based machine-learning models for predicting post-prand...

  • Article
  • Open Access
3 Citations
1,628 Views
18 Pages

Machine Learning-Driven D-Glucose Prediction Using a Novel Biosensor for Non-Invasive Diabetes Management

  • Pardis Sadeghi,
  • Shahriar Noroozizadeh,
  • Rania Alshawabkeh and
  • Nian Xiang Sun

1 March 2025

Developing reliable noninvasive diagnostic and monitoring systems for diabetes remains a significant challenge, especially in the e-healthcare domain, due to computational inefficiencies and limited predictive accuracy in current approaches. The curr...

  • Review
  • Open Access
14 Citations
23,238 Views
13 Pages

The History, Evolution and Future of Continuous Glucose Monitoring (CGM)

  • Clara Bender,
  • Peter Vestergaard and
  • Simon Lebech Cichosz

Continuous glucose monitoring (CGM) and flash glucose monitoring (FGM) systems have revolutionized diabetes management by delivering real-time, dynamic insights into blood glucose levels. This article provides a concise overview of the evolution of C...

  • Article
  • Open Access
86 Citations
7,102 Views
12 Pages

IoT and Cloud Computing in Health-Care: A New Wearable Device and Cloud-Based Deep Learning Algorithm for Monitoring of Diabetes

  • Ahmed R. Nasser,
  • Ahmed M. Hasan,
  • Amjad J. Humaidi,
  • Ahmed Alkhayyat,
  • Laith Alzubaidi,
  • Mohammed A. Fadhel,
  • José Santamaría and
  • Ye Duan

8 November 2021

Diabetes is a chronic disease that can affect human health negatively when the glucose levels in the blood are elevated over the creatin range called hyperglycemia. The current devices for continuous glucose monitoring (CGM) supervise the glucose lev...

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