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27,339 Results Found

  • Article
  • Open Access
2 Citations
1,759 Views
23 Pages

5 January 2025

Vegetation, as a fundamental component of terrestrial ecosystems, plays a pivotal role in the flux of water, heat, and nutrients between the lithosphere, biosphere, and atmosphere. Assessing the impacts of climate change and human activities on veget...

  • Article
  • Open Access
13 Citations
2,914 Views
18 Pages

19 September 2023

Climate and human activities are the basic driving forces that control and influence the spatial distribution and change of vegetation. Using trend analysis, the Hurst index, correlation analysis, the Moran index, path analysis, residual analysis, an...

  • Article
  • Open Access
28 Citations
6,089 Views
15 Pages

3 April 2019

Land use and land cover change (LUCC) and water resource utilization behavior and policy (WRUBAP) affect the hydrological cycle in different ways. Their effects on streamflow and hydrological balance components were analyzed in the Yiluo River Basin...

  • Article
  • Open Access
10 Citations
2,415 Views
16 Pages

Effectiveness of China’s Protected Areas in Mitigating Human Activity Pressure

  • Jian Chen,
  • Hong Shi,
  • Xin Wang,
  • Yiduo Zhang and
  • Zihan Zhang

Global protected areas are the key factor in maintaining biodiversity and ecosystem services. However, few studies use human activity pressure to assess the effectiveness of protected areas. This study constructed a human activity pressure index to a...

  • Article
  • Open Access
13 Citations
4,692 Views
16 Pages

27 January 2023

Vegetation suitability assessment is the premise of scientific vegetation restoration and identifying its effect factors is conducive to imposing more targeted measures. In this paper, we take 24 social-economic factors that may affect vegetation sui...

  • Article
  • Open Access
1,727 Views
17 Pages

Effects of Human Activities on Antibiotic Resistance Genes and Microbial Diversity in Lake Sediments

  • Rui Wang,
  • Min Li,
  • Haiying Li,
  • Xianyu Yin,
  • Hanlu Zhang,
  • Hongmei Wang,
  • Chengshi Ding and
  • Qing Chen

18 May 2025

Human activities are the main sources of antibiotic-resistant genes (ARGs) and mobile genetic elements (MGEs) in the ecosystems of lakes. This research analyzed the abundance of four ARGs (sulI, tetX, cmlA, and aac(6′)-Ib-cr) and one MGE (intI)...

  • Article
  • Open Access
6 Citations
3,179 Views
17 Pages

25 December 2022

Global enhanced human activities have deeply influenced grassland ecosystems. Quantifying the impact of human activities on grasslands is crucial to understanding the grassland dynamic change mechanism, such as grassland degradation, and to establish...

  • Article
  • Open Access
4 Citations
4,080 Views
14 Pages

25 May 2022

The islands of the Aegean Sea are areas of high biodiversity and endemism and harbor globally important seabird communities. Resident seabirds breed on offshore islands, where they often form strong nesting colonies. Breeding seabirds are important d...

  • Article
  • Open Access
7 Citations
4,423 Views
16 Pages

Effects of Environment and Human Activities on Plant Diversity in Wetlands along the Yellow River in Henan Province, China

  • Zhiliang Yuan,
  • Man Xiao,
  • Xiao Su,
  • He Zhao,
  • Yushan Li,
  • Huiping Zhang,
  • Ziyu Zhou,
  • Rui Qi,
  • Yun Chen and
  • Wei Wang

12 June 2022

Background and Objectives: The Yellow River is the sixth longest river in the world, and it is considered the mother river of China. Biodiversity conservation in the middle and lower reaches of the Yellow River is an urgent concern due to the impact...

  • Article
  • Open Access
27 Citations
4,601 Views
14 Pages

3 August 2020

Human activity is the major factor driving the wetland degradation in shallow lakes. Human exploitation of lake wetlands alters the habitats of wintering waterbirds, and, in turn, waterbird diversity in the shallow lakes. In the present study, we sur...

  • Article
  • Open Access
17 Citations
6,281 Views
11 Pages

Aschantin is a bioactive neolignan found in Magnolia flos with antiplasmodial, Ca2+-antagonistic, platelet activating factor-antagonistic, and chemopreventive activities. We investigated its inhibitory effects on the activities of eight major human c...

  • Article
  • Open Access
18 Citations
3,425 Views
20 Pages

19 October 2022

In recent years, regional habitat quality (HQ) has significantly degenerated, mainly attributed to human activities. Evaluating the spatio-temporal effects of human activities on HQ is crucial for maintaining regional ecosystem and conservation of la...

  • Article
  • Open Access
13 Citations
3,603 Views
12 Pages

18 June 2021

Bee pollen is an apiary product of great interest owing to its high nutritional and therapeutic properties. This study aimed to assess the cellular antioxidant activity and the antihemolytic effect of Castanea, Rubus, and Cistus bee pollens on human...

  • Article
  • Open Access
11 Citations
2,922 Views
19 Pages

Quantifying the Effects of Climate Variability, Land-Use Changes, and Human Activities on Drought Based on the SWAT–PDSI Model

  • Yanbing Zhu,
  • Baofu Li,
  • Lishu Lian,
  • Tianxiao Wu,
  • Junshan Wang,
  • Fangshu Dong and
  • Yunqian Wang

11 August 2022

Much attention has recently been devoted to the qualitative relationship between climate factors and drought; however, the influences of climate variability, land-use/cover changes (LUCC), and other human activities on drought have rarely been quanti...

  • Article
  • Open Access
1 Citations
1,039 Views
14 Pages

Effects of Climate Variables and Human Activities on Groundwater Level Fluctuations in Unconsolidated Sedimentary Aquifers: A Data-Driven Approach

  • Liu Yang,
  • Ming Gao,
  • Jiameng Chen,
  • Wenqing Shi,
  • Changhong Hou,
  • Zichun Liu,
  • Cheng Luo,
  • Jiahui Yu,
  • Xiangyu Yang and
  • Jie Dong

15 August 2025

Groundwater level (GWL) in unconfined aquifers is highly susceptible to climate variables and human activities, exhibiting nonlinear fluctuations; these can further contribute to or exacerbate environmental hazards, such as land subsidence. Understan...

  • Article
  • Open Access
1 Citations
774 Views
21 Pages

29 July 2025

The Inner Mongolia Plateau (IMP), situated in the arid and semi-arid ecological transition zone of northern China, is particularly vulnerable to both climate change and human activities. Understanding the spatiotemporal vegetation dynamics and their...

  • Article
  • Open Access
20 Citations
4,516 Views
13 Pages

Strong and Selective Inhibitory Effects of the Biflavonoid Selamariscina A against CYP2C8 and CYP2C9 Enzyme Activities in Human Liver Microsomes

  • So-Young Park,
  • Phi-Hung Nguyen,
  • Gahyun Kim,
  • Su-Nyeong Jang,
  • Ga-Hyun Lee,
  • Nguyen Minh Phuc,
  • Zhexue Wu and
  • Kwang-Hyeon Liu

Like flavonoids, biflavonoids, dimeric flavonoids, and polyphenolic plant secondary metabolites have antioxidant, antibacterial, antiviral, anti-inflammatory, and anti-cancer properties. However, there is limited data on their effects on cytochrome P...

  • Article
  • Open Access
3 Citations
2,217 Views
18 Pages

20 November 2024

Climate change and human activities were identified as the primary drivers of streamflow in arid alpine regions. However, limitations in observational data have resulted in a limited understanding of streamflow changes in these water sources, which h...

  • Article
  • Open Access
4 Citations
2,921 Views
17 Pages

Effects of Sponge-Derived Alkaloids on Activities of the Bacterial α-D-Galactosidase and Human Cancer Cell α-N-Acetylgalactosaminidase

  • Natalia Utkina,
  • Galina Likhatskaya,
  • Olesya Malyarenko,
  • Svetlana Ermakova,
  • Larisa Balabanova,
  • Lubov Slepchenko and
  • Irina Bakunina

During a search for glycosidase inhibitors among marine natural products, we applied an integrated in vitro and in silico approach to evaluate the potency of some aaptamines and makaluvamines isolated from marine sponges on the hydrolyzing activity o...

  • Article
  • Open Access
6 Citations
2,920 Views
15 Pages

Effects of Human Activities on Evapotranspiration and Its Components in Arid Areas

  • Yunfei Liu,
  • Dongwei Gui,
  • Changjun Yin,
  • Lei Zhang,
  • Dongping Xue,
  • Yi Liu,
  • Zeeshan Ahmed and
  • Fanjiang Zeng

With the increasing impact of human activities on the environment, evapotranspiration (ET) has changed in arid areas, which further affects the water resources availability in the region. Therefore, understanding the impact of human activities on ET...

  • Article
  • Open Access
13 Citations
3,508 Views
21 Pages

Anti-Inflammatory, Antioxidant Activities, and Phytochemical Characterization of Edible Plants Exerting Synergistic Effects in Human Gastric Epithelial Cells

  • Achille Parfait Nwakiban Atchan,
  • Orissa Charlène Monthe,
  • Armelle Deutou Tchamgoue,
  • Yeshvanthi Singh,
  • Shilpa Talkad Shivashankara,
  • Moorthy Karthika Selvi,
  • Gabriel Agbor Agbor,
  • Paolo Magni,
  • Stefano Piazza and
  • Uma Venkateswaran Manjappara
  • + 2 authors

27 February 2023

Dietary bioactive compounds from natural sources (e.g., herbal medicines, foods) are known to potentially suppress acute or chronic inflammation and promote the effectiveness of treatment to reduce the harmful effects of gastritis alone or in combina...

  • Article
  • Open Access
1 Citations
704 Views
20 Pages

Pharmaco-Toxicological Effects of Cachrys libanotis Extract: Antioxidant, Antimicrobial, and Cytotoxic Activities in Human Cell Lines and Embryonic Models

  • Mary Fucile,
  • Ioana Gabriela Macasoi,
  • Monica Negrea,
  • Diana Obistioiu,
  • Mariangela Marrelli,
  • Ersilia Alexa,
  • Cristina Dehelean,
  • Giancarlo Statti,
  • Filomena Conforti and
  • Iulia Pinzaru

We conducted a study to explore the potential of an enriched coumarin extract from Cachrys libanotis for the prevention and treatment of various diseases. The extract was prepared using pressurized cyclic solid–liquid extraction, and its safety...

  • Article
  • Open Access
6 Citations
4,251 Views
18 Pages

Biophysical and Biological Tools to Better Characterize the Stability, Safety and Efficacy of a Cosmeceutical for Acne-Prone Skin

  • Sabrina Sommatis,
  • Maria Chiara Capillo,
  • Cristina Maccario,
  • Elsa Liga,
  • Giulia Grimaldi,
  • Raffaele Rauso,
  • Pier Luca Bencini,
  • Stefania Guida,
  • Nicola Zerbinati and
  • Roberto Mocchi

13 February 2022

(1) Background: Acne is a widespread skin disease, especially among adolescents. Following the COVID-19 pandemic and the use of masks, the problem has been affecting a greater number of people, and the attention of the skin care beauty routine cosmet...

  • Article
  • Open Access
7 Citations
4,871 Views
13 Pages

EAM-2201, a synthetic cannabinoid, is a potent agonist of the cannabinoid receptors that is widely abused as an illicit recreational drug in combination with other drugs. To evaluate the potential of EAM-2201 as a perpetrator of drug–drug inter...

  • Article
  • Open Access
36 Citations
6,020 Views
21 Pages

21 September 2019

The purpose of activity recognition is to identify activities through a series of observations of the experimenter’s behavior and the environmental conditions. In this study, through feature selection algorithms, we researched the effects of a...

  • Article
  • Open Access
5 Citations
2,799 Views
34 Pages

7 September 2023

In this paper, the effects of climate change and human activities on the groundwater level and the concentration of pollutants, such as total dissolved solids (TDS), chloride, and sodium, were investigated in the western part of the Varamin Plain. Th...

  • Article
  • Open Access
1,068 Views
16 Pages

Effects of Climate Change and Human Activities on the Flow of the Muling River

  • Xiang Meng,
  • Chang-Lei Dai,
  • Yi-Ding Zhang,
  • Geng-Wei Liu,
  • Xiao Yang and
  • Xue Feng

In the context of global warming and the intensification of human activities, the change in runoff is also increasing. It is very important to determine the change in runoff for the rational utilization of water resources. In order to determine the i...

  • Article
  • Open Access
47 Citations
5,965 Views
22 Pages

Safety and Photoprotective Efficacy of a Sunscreen System Based on Grape Pomace (Vitis vinifera L.) Phenolics from Winemaking

  • Alexandra A. Hübner,
  • Fernanda D. Sarruf,
  • Camila A. Oliveira,
  • Alberto V. Neto,
  • Dominique C. H. Fischer,
  • Edna T. M. Kato,
  • Felipe R. Lourenço,
  • André Rolim Baby and
  • Elfriede M. Bacchi

In winemaking, a large amount of grape pomace is produced that is rich in polyphenolics and highly beneficial for human health, as phenols are useful for skin ultraviolet (UV) protection. In this investigation, we evaluated the safety and clinical ef...

  • Article
  • Open Access
50 Citations
8,539 Views
16 Pages

28 October 2013

We describe here the effects of three drugs that are either approved or have the potential for treating multiple sclerosis (MS) patients through the in vitro activities of human natural killer (NK) cells and dendritic cells (DCs). Our results indicat...

  • Article
  • Open Access
6 Citations
3,210 Views
14 Pages

Sensitivity of Neuroblastoma and Induced Neural Progenitor Cells to High-Intensity THz Radiation

  • Dmitry Sitnikov,
  • Veronika Revkova,
  • Inna Ilina,
  • Rimma Shatalova,
  • Pavel Komarov,
  • Evgenia Struleva,
  • Mikhail Konoplyannikov,
  • Vladimir Kalsin and
  • Vladimir Baklaushev

THz radiation induces a variety of processes in cells and has attracted the attention of researchers in recent decades. Here, data on the effects of high-intensity terahertz (THz) radiation on human directly reprogrammed neural progenitor cells (drNP...

  • Editorial
  • Open Access
5 Citations
3,831 Views
6 Pages

15 October 2024

The Special Issue focused on the water environment changes within watersheds due to its critical role in sustaining ecosystems, supporting biodiversity, and providing essential resources for human life [...]

  • Article
  • Open Access
838 Views
18 Pages

The Synergistic Effects of Climate Change and Human Activities on Wetland Expansion in Xinjiang

  • Jiaorong Qian,
  • Yaning Chen,
  • Yonghui Wang,
  • Yupeng Li,
  • Zhi Li,
  • Gonghuan Fang,
  • Chuanxiu Liu,
  • Yihan Wang and
  • Zhixiong Wei

15 September 2025

Wetlands function as crucial transitional zones between land and water ecosystems worldwide, contributing significantly to the stability of local ecosystems. However, there is limited research on landscape changes in Xinjiang’s arid interior re...

  • Article
  • Open Access
11 Citations
5,728 Views
17 Pages

Human Activity Recognition Based on Deep Learning and Micro-Doppler Radar Data

  • Tan-Hsu Tan,
  • Jia-Hong Tian,
  • Alok Kumar Sharma,
  • Shing-Hong Liu and
  • Yung-Fa Huang

15 April 2024

Activity recognition is one of the significant technologies accompanying the development of the Internet of Things (IoT). It can help in recording daily life activities or reporting emergencies, thus improving the user’s quality of life and saf...

  • Article
  • Open Access
4 Citations
5,636 Views
16 Pages

Prophylactic Oral Application of Activated Charcoal Mitigates Acute Campylobacteriosis in Human Gut Microbiota-Associated IL-10−/− Mice

  • Markus M. Heimesaat,
  • Niklas Schabbel,
  • Luis Q. Langfeld,
  • Nizar W. Shayya,
  • Soraya Mousavi and
  • Stefan Bereswill

23 January 2024

The incidence of human Campylobacter jejuni infections is increasing worldwide. It is highly desirable to prevent campylobacteriosis in individuals at risk for severe disease with antibiotics-independent non-toxic compounds. Activated charcoal (AC) h...

  • Article
  • Open Access
10 Citations
7,088 Views
17 Pages

18 June 2021

This study is the first to show that increased mitochondrial activities improved the antiaging effects of Aloe vera leaf skin fermented by Lactobacillus plantarum on UVb-irradiated skin fibroblasts. The fermented extract (AF) increased the activities...

  • Article
  • Open Access
33 Citations
12,910 Views
10 Pages

Effects of Eupatilin and Jaceosidin on Cytochrome P450 Enzyme Activities in Human Liver Microsomes

  • Hye Young Ji,
  • Sung Yeon Kim,
  • Dong Kyun Kim,
  • Ji Hyun Jeong and
  • Hye Suk Lee

16 September 2010

Eupatilin and jaceosidin are bioactive flavones found in the medicinal herbs of the genus Artemisia. These bioactive flavones exhibit various antioxidant, antiinflammatory, antiallergic, and antitumor activities. The inhibitory potentials of eupatili...

  • Article
  • Open Access
11 Citations
4,457 Views
16 Pages

Neglected tropical diseases affect the world’s poorest populations with soil-transmitted helminthiasis and schistosomiasis being among the most prevalent ones. Mass drug administration is currently the most important control measure, but the us...

  • Article
  • Open Access
1 Citations
1,658 Views
22 Pages

21 October 2024

The northern Tianshans region in the arid zone of northwestern China plays a key role in promoting high-quality development of the ecological environment. In recent years, ecological environmental protection in this region has encountered major chall...

  • Article
  • Open Access
5 Citations
2,247 Views
24 Pages

6 July 2024

In recent years, the runoff of numerous rivers has experienced substantial changes owing to the dual influences of climate change and human activities. This study focuses on the Lixian hydrological station’s controlled basin, located in the upp...

  • Article
  • Open Access
18 Citations
6,821 Views
14 Pages

15 August 2018

Climate change and human activities are the major factors affecting runoff and sediment load. We analyzed the inter-annual variation trends of the annual rainfall, air temperature, runoff and sediment load in the Xihe River Basin from 1969–2015...

  • Article
  • Open Access
5 Citations
2,239 Views
22 Pages

11 December 2022

Evapotranspiration plays a decisive role in the whole oasis ecosystem and is an important factor to maintain the ecological stability of oases. To quantitatively analyze the evapotranspiration differences of oases at different scales and the expansio...

  • Article
  • Open Access
15 Citations
2,512 Views
15 Pages

Effects of Human Activities on the Spatial Distribution, Ecological Risk and Sources of PTEs in Coastal Sediments

  • Weili Wang,
  • Cai Lin,
  • Lingqing Wang,
  • Ronggen Jiang,
  • Yang Liu,
  • Hui Lin and
  • Jinmin Chen

Potentially toxic elements (PTEs) have attracted substantial attention because of their widespread sources, long residue time and easy accumulation. PTEs in the surface sediments of inshore waters are strongly affected by human activities because the...

  • Article
  • Open Access
13 Citations
2,921 Views
17 Pages

29 September 2022

Soil moisture (SM), as a crucial variable in the soil–vegetation–atmosphere continuum, plays an important role in the terrestrial water cycle. Analyzing SM’s variation and driver factors is crucial to maintaining ecosystem diversity...

  • Article
  • Open Access
47 Citations
4,236 Views
14 Pages

Effects of Climate Factors and Human Activities on the Ecosystem Water Use Efficiency throughout Northern China

  • Xiaozheng Du,
  • Xiang Zhao,
  • Tao Zhou,
  • Bo Jiang,
  • Peipei Xu,
  • Donghai Wu and
  • Bijian Tang

24 November 2019

Global climate changes have increased the imbalance of water resources, especially in northern China, which comprises typical arid and semiarid regions. Large-scale afforestation has been implemented over the past three decades in northern China. The...

  • Review
  • Open Access
78 Citations
36,585 Views
18 Pages

28 December 2021

Red wine, an alcoholic beverage is composed of a spectrum of complex compounds such as water, alcohol, glycerol, organic acid, carbohydrates, polyphenols, and minerals as well as volatile compounds. Major factors that affect the levels of phenolic co...

  • Article
  • Open Access
4 Citations
3,566 Views
17 Pages

23 June 2022

Since the 21st century, large cities around the world have experienced the transition from economically destructive development to a harmonious eco-environment. Understanding the dynamic relationships between human activities and urban eco-environmen...

  • Article
  • Open Access
12 Citations
3,023 Views
17 Pages

16 October 2023

In recent years, vegetation on the Qinghai–Tibet Plateau (QTP) has undergone significant greening. However, the causal factors underpinning this phenomenon, whether attributable to temperature fluctuations, precipitation patterns, or anthropoge...

  • Article
  • Open Access
16 Citations
3,806 Views
12 Pages

31 January 2022

The aeolian desertification in Mu Us Sandy Land (MUSL) in northern China have been paid much attention, but the relative contributions of climate change and human activities to desertification dynamics are still not clear. Based on the Landsat MSS, T...

  • Article
  • Open Access
12 Citations
6,459 Views
8 Pages

12 November 2015

A series of butylphthalide derivatives (BPDs) 1–8 were isolated from the extract of the dried rhizome of Ligusticum chuanxiong Hort. (Umbelliferae). The cytotoxic activities of BPDs 1–8 were evaluated using a panel of human cancer cell lines. In addi...

  • Article
  • Open Access
4 Citations
870 Views
20 Pages

19 March 2025

Net primary productivity (NPP) is a critical indicator for evaluating the carbon sequestration potential of an ecosystem and regional sustainable development, as its spatiotemporal dynamics are jointly influenced by natural and anthropogenic factors....

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