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27 Results Found

  • Article
  • Open Access
1,137 Views
13 Pages

The goal of this paper was to determine the efficacy of the surgical treatment of two-wall peri-implant defects filled with L-PRF/xenograft block in the reduction of peri-implant marginal bone levels after 12 months. Ten patients with two-wall peri-i...

(This article belongs to the Special Issue Peri-Implant Diseases: Bridging the Gap Between Research and Clinical Daily Practice)
  • Article
  • Open Access
5 Citations
3,814 Views
21 Pages

Azimuth Full-Aperture Processing of Spaceborne Squint SAR Data with Block Varying PRF

  • Zhuo Zhang,
  • Wei Xu,
  • Pingping Huang,
  • Weixian Tan and ,
  • Zhiqi Gao and
  • Yaolong Qi
  • + 1 author+ 0 author

30 November 2022

The block varying pulse repetition frequency (BV-PRF) scheme applied to spaceborne squint sliding-spotlight synthetic aperture radar (SAR) can resolve large-range cell migration (RCM) and reduce azimuth signal non-uniformity. However, in the BV-PRF s...

(This article belongs to the Special Issue Radar Technology and Data Processing)
  • Case Report
  • Open Access
8 Citations
5,735 Views
7 Pages

Leucocyte- and Platelet-Rich Fibrin Block: Its Use for the Treatment of a Large Cyst with Implant-Based Rehabilitation

  • Rodolfo Mauceri,
  • Denise Murgia,
  • Orazio Cicero,
  • Luigi Paternò and ,
  • Luca Fiorillo,
  • Viviana De Caro and
  • Giuseppina Campisi
  • + 2 authors+ 0 author

20 February 2021

The management of critical-size bone defects is still demanding. Recently, autologous platelet concentrates in combination with bone substitute have been applied and reported in a few studies. Our aim is to report the healing of a critical-size alveo...

(This article belongs to the Section Dentistry and Oral Health)
  • Article
  • Open Access
3 Citations
2,757 Views
14 Pages

To tackle the problems of Doppler spectrum, aliasing caused by azimuth beam scanning and azimuthal serious non-uniform sampling in squint sliding spotlight synthetic aperture radar (SAR) with varying repetition frequency technology, the azimuth sampl...

(This article belongs to the Topic Radar Signal and Data Processing with Applications)
  • Brief Report
  • Open Access
1 Citations
1,035 Views
11 Pages

Horizontal Platelet-Rich Fibrin Membrane Block for Peri-Implant Soft Tissue Augmentation: An Experimental Animal Study with Clinical Illustration

  • Hao Zeng,
  • Yan Wei,
  • Shimin Yu,
  • Xiaoxin Zhang and ,
  • Yun Qiu,
  • Richard J. Miron,
  • Yulan Wang and
  • Yufeng Zhang
  • + 3 authors+ 0 author

4 March 2026

Background/Objectives: Adequate peri-implant soft tissue thickness is essential for long-term peri-implant health and esthetics. Horizontal platelet-rich fibrin (H-PRF) has been proposed to support soft tissue regeneration; however, experimental and...

(This article belongs to the Section Dental Implantology)
  • Article
  • Open Access
10 Citations
4,322 Views
19 Pages

Mutagenic Analysis of the HIV Restriction Factor Shiftless

  • Niklas Jäger,
  • Shreya Ahana Ayyub,
  • Natalia Korniy,
  • Frank Peske and ,
  • Markus Hoffmann,
  • Marina V. Rodnina and
  • Stefan Pöhlmann
  • + 2 authors+ 0 author

30 June 2022

The interferon-induced host cell protein shiftless (SFL) was reported to inhibit human immunodeficiency virus (HIV) infection by blocking the –1 programmed ribosomal frameshifting (–1PRF) required for expression of the Gag-Pol polyprotein...

(This article belongs to the Section General Virology)
  • Article
  • Open Access
30 Citations
4,125 Views
13 Pages

Platelet-Rich Fibrin Increases BMP2 Expression in Oral Fibroblasts via Activation of TGF-β Signaling

  • Zahra Kargarpour,
  • Jila Nasirzade,
  • Layla Panahipour,
  • Goran Mitulović and ,
  • Richard J. Miron and
  • Reinhard Gruber
  • + 1 author+ 0 author

Solid platelet-rich fibrin (PRF), consisting of coagulated plasma from fractionated blood, has been proposed to be a suitable carrier for recombinant bone morphogenetic protein 2 (BMP2) to target mesenchymal cells during bone regeneration. However, w...

(This article belongs to the Special Issue The Molecules and Stem Cells in Bone Regeneration)
  • Article
  • Open Access
55 Citations
8,172 Views
14 Pages

Biological and Mechanical Properties of Platelet-Rich Fibrin Membranes after Thermal Manipulation and Preparation in a Single-Syringe Closed System

  • Dorottya Kardos,
  • István Hornyák,
  • Melinda Simon,
  • Adél Hinsenkamp and ,
  • Bence Marschall,
  • Róbert Várdai,
  • Alfréd Kállay-Menyhárd,
  • Balázs Pinke,
  • László Mészáros and
  • Zsombor Lacza
  • + 7 authors+ 2 authors

1 November 2018

Platelet-rich fibrin (PRF) membrane is a three-dimensional biodegradable biopolymer, which consists of platelet derived growth factors enhancing cell adhesion and proliferation. It is widely used in soft and hard tissue regeneration, however, there a...

(This article belongs to the Special Issue Biobased and/or Biodegradable Polymeric Materials)
  • Article
  • Open Access
37 Citations
5,425 Views
10 Pages

Liquid Platelet-Rich Fibrin and Heat-Coagulated Albumin Gel: Bioassays for TGF-β Activity

  • Zahra Kargarpour,
  • Jila Nasirzade,
  • Layla Panahipour,
  • Richard J. Miron and
  • Reinhard Gruber

6 August 2020

Liquid platelet-rich fibrin (PRF) can be prepared by high centrifugation forces separating the blood into a platelet-poor plasma (PPP) layer and a cell-rich buffy coat layer, termed concentrated PRF (C-PRF). Heating the liquid PPP was recently introd...

(This article belongs to the Section Biomaterials)
  • Article
  • Open Access
25 Citations
5,364 Views
11 Pages

Platelet-Rich Fibrin Can Neutralize Hydrogen Peroxide-Induced Cell Death in Gingival Fibroblasts

  • Zahra Kargarpour,
  • Jila Nasirzade,
  • Francesca Di Summa,
  • Layla Panahipour and ,
  • Richard J. Miron and
  • Reinhard Gruber
  • + 1 author+ 0 author

Hydrogen peroxide is a damage signal at sites of chronic inflammation. The question arises whether platelet-rich fibrin (PRF), platelet-poor plasma (PPP), and the buffy coat can neutralize hydrogen peroxide toxicity and thereby counteract local oxida...

(This article belongs to the Special Issue Enzymatic and Non-Enzymatic Molecules with Antioxidant Function)
  • Article
  • Open Access
6 Citations
7,423 Views
11 Pages

Objectives: To investigate the efficacy and safety of an improved ultrasound-guided pulsed radiofrequency (PRF) and nerve block (NB) for patients with pudendal neuralgia (PN). Methods: This retrospective analysis included 88 adults with PN treated in...

(This article belongs to the Special Issue Advances in Study of Molecular and Cellular Mechanisms Underlying Pain and Itch)
  • Article
  • Open Access
1 Citations
1,947 Views
16 Pages

22 October 2025

Background and Objectives: Chronic migraines are a disabling neurological disorder with limited response to preventive pharmacological treatments. Greater occipital nerve (GON)-targeted radiofrequency (RF) procedures have emerged as promising interve...

(This article belongs to the Section Neurology)
  • Article
  • Open Access
25 Citations
5,278 Views
13 Pages

Bond Quality and Durability of Cross-Laminated Flattened Bamboo and Timber (CLBT)

  • Shiyu Yang,
  • Hongping Li,
  • Benhua Fei,
  • Xiubiao Zhang and
  • Xiaohuan Wang

11 August 2022

To achieve value-added utilization of domestic bamboo and plantation wood resources, this study investigated the feasibility of using flattened bamboo and Chinese fir for manufacturing cross-laminated bamboo and timber (CLBT). Two types of adhesives,...

(This article belongs to the Section Wood Science and Forest Products)
  • Article
  • Open Access
3 Citations
2,407 Views
14 Pages

Synthesis, Microstructure, and Electrical Conductivity of Eutectic Composites in MF2–RF3 (M = Ca, Sr, Ba; R = La–Nd) Systems

  • Irina I. Buchinskaya,
  • Natalia A. Arkharova,
  • Anna G. Ivanova,
  • Nikolay I. Sorokin and
  • Denis N. Karimov

15 August 2023

Multiphase fluoride polycrystalline eutectics pRF3 × qMF2 forming in the MF2–RF3 (M = Ca, Sr, Ba; R = La–Nd) binary systems were synthesized by the directional crystallization technique from a melt. The phase composition, morphology...

(This article belongs to the Section Composites Manufacturing and Processing)
  • Article
  • Open Access
16 Citations
13,165 Views
11 Pages

Clinical Management of Chronic Pelvic Pain in Endometriosis Unresponsive to Conventional Therapy

  • Augusto Pereira,
  • Manuel Herrero-Trujillano,
  • Gema Vaquero,
  • Lucia Fuentes and ,
  • Sofia Gonzalez,
  • Agustin Mendiola and
  • Tirso Perez-Medina
  • + 2 authors+ 0 author

13 January 2022

Background: Although several treatments are currently available for chronic pelvic pain, 30–60% of patients do not respond to them. Therefore, these therapeutic options require a better understanding of the mechanisms underlying endometriosis-i...

(This article belongs to the Special Issue Endometriosis: Advances in Diagnosis and Treatment)
  • Article
  • Open Access
421 Views
18 Pages

Clinical Outcomes and Factors Associated with Response to Fluoroscopy-Guided Cervical Medial Branch Pulsed Radiofrequency in Chronic Cervical Facet Joint Pain: A Retrospective Cohort Study

  • Nevcihan Şahutoğlu Bal,
  • Şükriye Dadalı,
  • Ali Çoştu,
  • Gülçin Babaoğlu and ,
  • Ülkü Sabuncu,
  • Emel Başar and
  • Erkan Yavuz Akçaboy
  • + 2 authors+ 0 author

15 September 2026

Background and Objectives: Pulsed radiofrequency (PRF) of the cervical medial branches is a non-destructive neuromodulatory option for chronic cervical facet joint pain, yet evidence regarding the durability of clinical response and factors associate...

(This article belongs to the Special Issue Precision and Regenerative Interventional Pain Medicine: Imaging-Guided, Neuromodulatory and Minimally Invasive Advances)
  • Article
  • Open Access
8 Citations
3,695 Views
13 Pages

12 October 2022

The differences of physical and mechanical properties of different laminations, such as softwood, hardwood or other structural composite lumber, in hybrid cross-laminated timber (HCLT), lead to their dimensional stability and bonding performance more...

(This article belongs to the Section Building Structures)
  • Article
  • Open Access
10 Citations
2,952 Views
18 Pages

Ritonavir Blocks Hepatitis E Virus Internalization and Clears Hepatitis E Virus In Vitro with Ribavirin

  • Putu Prathiwi Primadharsini,
  • Shigeo Nagashima,
  • Masaharu Takahashi,
  • Kazumoto Murata and
  • Hiroaki Okamoto

3 November 2022

Hepatitis E virus (HEV) is increasingly recognized as the leading cause of acute hepatitis. Although HEV infections are mostly self-limiting, a chronic course can develop especially in those with immunocompromised state. Ribavirin is currently used t...

(This article belongs to the Special Issue Viral Hepatitis Treatment 2.0)
  • Article
  • Open Access
7 Citations
4,475 Views
34 Pages

7 September 2025

The growing need for sustainable and resource-efficient materials increasingly promotes the use of block-glued laminated timber (glulam) in buildings and civil structures such as bridges. While timber is renewable and sustainable, the formaldehyde-ba...

(This article belongs to the Special Issue Advancements in Green Building Materials, Structures, and Techniques)
  • Article
  • Open Access
1 Citations
543 Views
30 Pages

SoP-CTR: A Lightweight Stream Cipher with Beyond-Birthday-Bound Security for IoT and Embedded Devices

  • Andriani Adi Lestari,
  • Suryadi MT,
  • Kalamullah Ramli,
  • Susila Windarta and
  • Teddy Surya Gunawan

As systems migrate toward post-quantum readiness, symmetric keys are kept longer and protect larger data volumes, a regime in which keystream security beyond the birthday bound matters. The dominant block–cipher counter mode, AES-CTR (Advanced...

(This article belongs to the Section Cryptography and Cryptology)
  • Article
  • Open Access
37 Citations
4,106 Views
9 Pages

27 February 2021

Previous studies have proved that Larix kaempferi is a good material for preparing cross-laminated timber (CLT), but under bending shear stress, CLT made by Larix kaempferi is prone to the phenomenon of bonding face cracking, which seriously affects...

(This article belongs to the Section Polymer Applications)
  • Article
  • Open Access
8 Citations
3,536 Views
13 Pages

Immunogenicity and Antigenicity of Rabbit Hepatitis E Virus-Like Particles Produced by Recombinant Baculoviruses

  • Huimin Bai,
  • Michiyo Kataoka,
  • Yasushi Ami,
  • Yuriko Suzaki and ,
  • Naokazu Takeda,
  • Masamichi Muramatsu and
  • Tian-Cheng Li
  • + 2 authors+ 0 author

9 August 2021

Rabbit hepatitis E virus (HEV) is a novel HEV belonging to genotype 3 (HEV-3) in the Orthohepevirus A species of the genus Hepevirus, family Hepeviridae. Rabbit HEV was originally isolated from rabbits and found to cause zoonotic infection. Although...

(This article belongs to the Special Issue Emerging Technologies and Novel Approaches to Veterinary Viral Vaccine Development)
  • Article
  • Open Access
476 Views
25 Pages

14 June 2026

To address the inherent drawbacks of micro-arc oxidation (MAO), this study employed MAO combined with sol–gel processing to fabricate ZrO2/Al2O3-CeO2 composite coatings on ZrH1.8 surfaces, aiming to solve the hydrogen evolution problem of zirco...

(This article belongs to the Section Composite Coatings)
  • Article
  • Open Access
9 Citations
3,840 Views
13 Pages

Effect of Novel AKT Inhibitor Vevorisertib as Single Agent and in Combination with Sorafenib on Hepatocellular Carcinoma in a Cirrhotic Rat Model

  • Keerthi Kurma,
  • Ayca Zeybek Kuyucu,
  • Gaël S. Roth,
  • Nathalie Sturm and ,
  • Marion Mercey-Ressejac,
  • Giovanni Abbadessa,
  • Yi Yu,
  • Herve Lerat,
  • Patrice N. Marche and
  • Zuzana Macek Jilkova
  • + 6 authors+ 1 author

19 December 2022

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related mortality worldwide. The AKT pathway is often activated in HCC cases, and a longer exposure to tyrosine kinase inhibitors such as sorafenib may lead to over-activation of t...

(This article belongs to the Special Issue Toward a New Era in the Management of Hepatocellular Carcinoma: Novel Perspective on Therapeutic Options and Biomarkers)
  • Article
  • Open Access
1 Citations
2,103 Views
12 Pages

Analysis and Tracking of Intra-Needle Ultrasound Pleural Signals for Improved Anesthetic Procedures in the Thoracic Region

  • Fu-Wei Su,
  • Chia-Wei Yang,
  • Ching-Fang Yang,
  • Yi-En Tsai and ,
  • Wei-Nung Teng and
  • Huihua Kenny Chiang
  • + 1 author+ 0 author

21 March 2025

Background: Ultrasonography is commonly employed during thoracic regional anesthesia; however, its accuracy can be affected by factors such as obesity and poor penetration through the rib window. Needle-sized ultrasound transducers, known as intra-ne...

(This article belongs to the Special Issue Biosensors for Monitoring and Diagnostics)
  • Article
  • Open Access
41 Citations
5,431 Views
20 Pages

Combined Inhibition of TGF-β1-Induced EMT and PD-L1 Silencing Re-Sensitizes Hepatocellular Carcinoma to Sorafenib Treatment

  • Ritu Shrestha,
  • Prashanth Prithviraj,
  • Kim R. Bridle,
  • Darrell H. G. Crawford and
  • Aparna Jayachandran

27 April 2021

Hepatocellular carcinoma (HCC) is the most common type of primary hepatic malignancy. HCC is one of the leading causes of cancer deaths worldwide. The oral multi-tyrosine kinase inhibitor Sorafenib is the standard first-line therapy in patients with...

(This article belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
  • Article
  • Open Access
15 Citations
9,093 Views
14 Pages

CBCT in Dental Implantology: A Key Tool for Preventing Peri-Implantitis and Enhancing Patient Outcomes

  • Souheil Hussaini,
  • Michael Glogauer,
  • Zeeshan Sheikh and
  • Haider Al-Waeli

26 June 2024

(1) Introduction: Trust is a cornerstone of the patient–physician relationships. Unforeseen complications in the health care system could jeopardize patients’ trust in their physicians. (2) Aim: This article presents a quantitative figure...

(This article belongs to the Section Oral Hygiene, Periodontology and Peri-implant Diseases)