The main goal of this review is to provide an updated overview of the involvement of the RNA-binding protein (RBP) HuD, encoded by the ELAVL4 gene, in nervous system development, maintenance, and function, and its emerging role in nervous system dise...
HuD (also known as ELAVL4) is an RNA–binding protein belonging to the human antigen (Hu) family that regulates stability, translation, splicing, and adenylation of target mRNAs. Unlike ubiquitously distributed HuR, HuD is only expressed in certain ty...
The neuronal Hu/ELAV-like proteins HuB, HuC and HuD are a class of RNA-binding proteins that are crucial for proper development and maintenance of the nervous system. These proteins bind to AU-rich elements (AREs) in the untranslated regions (3′-UTRs...
The RNA-binding protein HuD (a.k.a., ELAVL4) is involved in neuronal development and synaptic plasticity mechanisms, including addiction-related processes such as cocaine conditioned-place preference (CPP) and food reward. The most studied function o...
The RNA-binding protein HuD has been shown to play a crucial role in gene regulation in the nervous system and is involved in various neurological and psychiatric diseases. In this study, through the creation of an interaction network on HuD and its...
The neuron-specific Elav-like Hu RNA-binding proteins were described to play an important role in neuronal differentiation and plasticity by ensuring the post-transcriptional control of RNAs encoding for various proteins. Although Elav-like Hu protei...
An automotive augmented reality head-up display (AR-HUD) can provide an immersive experience for users and is anticipated to become one of the ultimate terminals for human–machine interaction in future intelligent vehicles within the context of...
This national study is an effort to measure transportation costs and affordability for the major Housing and Urban Development (HUD) housing assistance programs since the transportation costs are the second largest expense of American households. Thi...
As the global traffic environment becomes increasingly complex, driving safety issues have become more prominent, making manual-response driving warning systems (DWSs) essential. Augmented reality head-up display (AR-HUD) technology can project infor...
The use of augmented reality head-up displays (AR-HUD) in automobile safety driving has drawn more and more interest in recent years. An AR-HUD display system should be developed to fit the vehicle and the complicated traffic environment in order to...
In-vehicle Augmented Reality Head-Up Displays (AR-HUDs) enhance driving performance and experience by presenting critical information such as navigation cues and collision warnings. Although many studies have investigated the efficacy of AR-HUD navig...
Current research on multimodal AR-HUD navigation systems primarily focuses on the presentation forms of auditory and visual information, yet the effects of synchrony between auditory and visual prompts as well as prompt timing on driving behavior and...
Adverse road conditions, particularly foggy weather, significantly impair drivers’ abilities to gather information and make judgments in response to unexpected events. To investigate the impact of different Augmented Reality-Head-Up Display (AR...
Augmented Reality Head-Up Displays (AR-HUDs) enhance driver perception and safety, yet optimal hazard warning design remains unclear. This study examines three AR-HUD crash warning icon types (BD, BR, BW) across various turning scenarios. Using a 360...
While astrocyte-to-neuron (AtN) reprogramming holds great promise in regenerative medicine, the molecular mechanisms that govern this unique biological process remain elusive. To understand the function of miRNAs during the AtN reprogramming process,...
Background: The interface design of in-vehicle head-up display (HUD) is an enlarging research area with interface usability as its core; usability reflects all perspectives of human—machine interaction and thus the evaluation and optimization o...
Black-grass (Alopecurus myosuroides Huds.) is a common weed in Chinese wheat fields, and has become troublesome due to its evolution of herbicide resistance. One black-grass population (HN-14) collected from a wheat field where herbicides were applie...
Post-transcriptional mechanisms play critical roles in the control of gene expression during neuronal development and maturation as they allow for faster responses to environmental cues and provide spatially-restricted compartments for local control...
The essential oil in leaves of Polygonum minus Huds., a local aromatic plant, were identified by a pipeline of gas chromatography (GC) techniques coupled with mass-spectrometry (MS), flame ionization detector (FID) and two dimensional gas chromatogra...
Intuitive and safe interfaces for robots are challenging issues in robotics. Robo-HUD is a gadget-less interaction concept for contactless operation of industrial systems. We use virtual collision detection based on time-of-flight sensor data, combin...
Augmented reality heads-up displays (AR-HUDs) have a much richer display than traditional heads-up displays. An ideal AR-HUD requires two or more focal planes to display basic and interactive driving information to the car driver separately. We prese...
Self-driving vehicles are emerging as a result of technological advances, and the range of human behavior is expanding. The collateral information on driving is increasing, and head-up displays (HUDs) can be coupled with augmented reality displays to...
In-vehicle voice assistants face usability challenges due to limitations in delivering feedback within the constraints of the driving environment. The presented study explores the potential of Rich Visual Feedback (RVF) on Head-Up Displays (HUDs) as...
Enhanced Vision System (EVS) offers a display advantage that conventional devices lack, enabling interface information to be overlaid on real-world imagery. However, information overload, especially in complex environments, can reduce the recognizabi...
Head-up displays (HUDs), a novel form of virtual display, are characterized by their optical structure as a typical binocular virtual display system. This structure exhibits the effect of binocular parallax on visual perception, especially when diver...
From previous studies of negatively correlating the expression of human METCAM/MUC18 with the pathology of nasopharyngeal carcinoma (NPC), we have suggested that human METCAM/MUC18 (huMETCAM/MUC18) might play a tumor suppressor role in the developmen...
This study investigates the impact of extreme weather conditions (specifically heavy rain and fog) on drivers’ situational awareness by analyzing variations in illumination levels. The primary objective is to identify optimal color wavelengths...
No standard diagnostic method or surgical treatment for congenital isolated hypoganglionosis (CIHG) has been established. This study aimed to analyze the clinical outcomes of patients with CIHG and identify the best surgical interventions provided th...
The sugar composition and content of fruit have a significant impact on their flavor and taste. In pitaya, or dragon fruit, sweetness is a crucial determinant of fruit taste and consumer preference. The sugars will eventually be exported transporters...
N6-methyladenosine (m6A) is the most prevalent internal RNA modification. Here, we demonstrate that coxsackievirus B3 (CVB3), a common causative agent of viral myocarditis, induces m6A modification primarily at the stop codon and 3′ untranslate...
Three-dimensional (3D) bioprinting is one of the most promising methodologies that are currently in development for the replacement of animal experiments. Bioprinting and most alternative technologies rely on animal-derived materials, which compromis...
Background: Alcohol use disorder in the context of heroin addiction presents a significant challenge for clinicians, particularly in selecting the most appropriate pharmacological treatment. Methods: The present study aimed to retrospectively evaluat...
The plurality of current infotainment devices within the in-vehicle space produces an unprecedented volume of incoming data that overwhelm the typical driver, leading to higher collision probability. This work presents an investigation to an alternat...
With the development of cloud storage and privacy protection, reversible data hiding in encrypted images (RDHEI) plays the dual role of privacy protection and secret information transmission. RDHEI has a good application prospect and practical value....
Plastid trnL-trnF and nuclear ribosomal ITS sequences were obtained from selected wild-type individuals of Polygonum minus Huds. in Peninsular Malaysia. The 380 bp trnL-trnF sequences of the Polygonum minus accessions were identical. Therefore, the t...
The adoption of self-driving technologies requires addressing public concerns about their reliability and trustworthiness. To understand how user experience in self-driving vehicles is influenced by the level of risk and head-up display (HUD) informa...
Controlling the in-car environment, including temperature and ventilation, is necessary for a comfortable driving experience. However, it often distracts the driver’s attention, potentially causing critical car accidents. In the present study,...
Head-up displays (HUDs) can effectively enhance driving safety by projecting information—such as speed and maps—onto the windshield, thereby reducing blind spots caused by drivers looking down. As drivers need to observe road conditions w...
This study proposes a pupil-tracking method applicable to drivers both with and without sunglasses on, which has greater compatibility with augmented reality (AR) three-dimensional (3D) head-up displays (HUDs). Performing real-time pupil localization...
Alopecurus myosuroides Huds. is an important pinoxaden-resistant grass weed in many countries of Europe. Recently, the low efficacy of pinoxaden was reported in winter cereals in Croatia, but a preliminary dose–response trial showed no herbicide resi...
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Purpose: This paper describes SalHUD, a prototype web-based application for visualizing health data from Puerto Rico. Our initial focus was to provide interactive maps displaying years of potential life lost (YPLL). Methods: The public-use mortality...
Phenolic profiling of ten plant samples of Mentha rotundifolia (L.) Huds. collected from different bioclimatic areas of Tunisia, was for the first time carried out by using a fast ultra-high-performance liquid chromatography (UHPLC)-high resolution t...
The origin of biopolymers is a central question in origins of life research. In extant life, proteins are coded linear polymers made of a fixed set of twenty alpha-L-amino acids. It is likely that the prebiotic forerunners of proteins, or protopeptid...
The technological process of agricultural production is inextricably linked to the movement of a large number of goods, ranging from the supply of raw materials to their conversion and delivery of finished products. In the implementation of freight f...
Most contemporary theories for the chemical origins of life include the prebiotic synthesis of informational polymers, including strong interpretations of the RNA World hypothesis. Existing challenges to the prebiotic emergence of RNA have encouraged...
Objectives: Limitations of widespread current COVID-19 diagnostic testing exist in both the pre-analytical and analytical stages. To alleviate these limitations, we developed a universal saliva processing protocol (SalivaSTAT) that would enable an ex...
Phosphorylation reactions of glycerol were studied using different inorganic phosphates such as sodium phosphate, trimetaphosphate (a condensed phosphate), and struvite. The reactions were carried out in two non-aqueous solvents: formamide and a eute...
Alopecurus myosuroides Huds. has become one of the most abundant grass weeds in Europe. High percentages of winter-annual crops in the rotation, earlier sowing of winter wheat and non-inversion tillage favor A.myosuroides. Additionally, many populati...
In meadow fescue (Festuca pratensis Huds.), a perennial fodder grass plant characterized by high quality and yield potential, seed shattering makes seed production difficult. The objective of the research was to compare two subpopulations, differing...
The core of HIV-1 viruses bearing the capsid change N74D (HIV-1-N74D) do not bind the human protein CPSF6. In primary human CD4+ T cells, HIV-1-N74D viruses exhibit an infectivity defect when compared to wild-type. We first investigated whether loss...
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