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  • Article
  • Open Access
22 Citations
28,292 Views
10 Pages

A Novel Model of Meibomian Gland Dysfunction Induced with Complete Freund’s Adjuvant in Rabbits

  • Hideki Miyake,
  • Tomoko Oda,
  • Osamu Katsuta,
  • Masaharu Seno and
  • Masatsugu Nakamura

9 February 2017

A novel meibomian gland dysfunction (MGD) model induced by the injection of complete Freund’s adjuvant (CFA) in rabbits was developed to facilitate the understanding of the pathophysiology of MGD with meibomitis. In addition, we sought to evaluate tr...

  • Review
  • Open Access
69 Citations
27,527 Views
24 Pages

14 January 2022

The autonomic nervous system (ANS) confers neural control of the entire body, mainly through the sympathetic and parasympathetic nerves. Several studies have observed that the physiological functions of the eye (pupil size, lens accommodation, ocular...

  • Review
  • Open Access
10 Citations
25,212 Views
20 Pages

22 September 2024

People with aphantasia exhibit the inability to voluntarily generate or form mental imagery in their minds. Since the term “aphantasia” was proposed to describe this, it has gained increasing attention from psychiatrists, neuroscientists,...

(This article belongs to the Special Issue Visual Mental Imagery System: How We Image the World)
  • Review
  • Open Access
30 Citations
23,251 Views
16 Pages

Pseudomyopia: A Review

  • María García-Montero,
  • Gema Felipe-Márquez,
  • Pedro Arriola-Villalobos and
  • Nuria Garzón

4 March 2022

This review has identified evidence about pseudomyopia as the result of an increase in ocular refractive power due to an overstimulation of the eye’s accommodative mechanism. It cannot be confused with the term “secondary myopia”, w...

  • Article
  • Open Access
19 Citations
21,105 Views
21 Pages

Natural Perspective: Mapping Visual Space with Art and Science

  • Alistair Burleigh,
  • Robert Pepperell and
  • Nicole Ruta

Following its discovery in fifteenth-century Italy, linear perspective has often been hailed as the most accurate method of projecting three-dimensional visual space onto a two-dimensional picture plane. However, when we survey the history of Europea...

  • Review
  • Open Access
42 Citations
19,624 Views
22 Pages

Toxic External Exposure Leading to Ocular Surface Injury

  • Steven H. Rauchman,
  • Brandon Locke,
  • Jacqueline Albert,
  • Joshua De Leon and ,
  • Morgan R. Peltier and
  • Allison B. Reiss
  • + 1 author+ 0 author

3 April 2023

The surface of the eye is directly exposed to the external environment, protected only by a thin tear film, and may therefore be damaged by contact with ambient particulate matter, liquids, aerosols, or vapors. In the workplace or home, the eye is su...

  • Feature Paper
  • Review
  • Open Access
97 Citations
19,365 Views
31 Pages

Non-Arteritic Anterior Ischemic Optic Neuropathy (NA-AION): A Comprehensive Overview

  • Maria Letizia Salvetat,
  • Francesco Pellegrini,
  • Leopoldo Spadea,
  • Carlo Salati and
  • Marco Zeppieri

9 November 2023

Non-arteritic anterior ischemic optic neuropathy (NA-AION) represents one of the most important causes of blindness or severely impaired vision in middle-aged and elderly people. Unilateral optic disc edema and abrupt, painless vision loss are its de...

  • Review
  • Open Access
36 Citations
19,280 Views
13 Pages

Overview on Defocus Incorporated Multiple Segments Lenses: A Novel Perspective in Myopia Progression Management

  • Matteo Mario Carlà,
  • Francesco Boselli,
  • Federico Giannuzzi,
  • Gloria Gambini and ,
  • Tomaso Caporossi,
  • Umberto De Vico,
  • Alfonso Savastano,
  • Antonio Baldascino,
  • Clara Rizzo and
  • Stanislao Rizzo
  • + 6 authors+ 1 author

2 April 2022

Myopia is becoming more common across the world, affecting approximately two billion people and rising. Different kinds of therapies (optical, pharmaceutical, environmental, or behavioral) have been proposed to decrease myopia progression, but with v...

  • Article
  • Open Access
21 Citations
19,038 Views
35 Pages

10 June 2021

This review describes the subjective experience of visual aura in migraine, outlines theoretical models of this phenomenon, and explores how these may be linked to neurochemical, electrophysiological, and psychophysical differences in sensory process...

(This article belongs to the Special Issue The Visual Aura in Migraine)
  • Review
  • Open Access
21 Citations
17,642 Views
15 Pages

Using Eye Movements to Understand how Security Screeners Search for Threats in X-Ray Baggage

  • Nick Donnelly,
  • Alex Muhl-Richardson,
  • Hayward J. Godwin and
  • Kyle R. Cave

4 June 2019

There has been an increasing drive to understand failures in searches for weapons and explosives in X-ray baggage screening. Tracking eye movements during the search has produced new insights into the guidance of attention during the search, and the...

(This article belongs to the Special Issue Eye Movements and Visual Cognition)
  • Article
  • Open Access
3 Citations
16,274 Views
11 Pages

A Thickness Illusion: Horizontal Is Perceived as Thicker than Vertical

  • Jasper M. De Waard,
  • Erik Van der Burg and
  • Christian N. L. Olivers

4 January 2019

We report two psychophysical experiments that investigate a visual illusion that is considered common knowledge among type designers, but has never been studied scientifically. Specifically, the thickness of a horizontal line is overestimated in rela...

  • Review
  • Open Access
104 Citations
16,050 Views
18 Pages

21 August 2023

Minimally invasive glaucoma surgery (MIGS) has emerged as a novel approach in the glaucoma treatment spectrum, offering a range of diverse procedures and devices aimed at reducing intraocular pressure (IOP). MIGS can be broadly classified into severa...

(This article belongs to the Special Issue Recent Advances in Glaucoma: Diagnosis and Treatment)
  • Review
  • Open Access
21 Citations
15,840 Views
7 Pages

Current Perspective on Retinal Migraine

  • Yu Jeat Chong,
  • Susan P. Mollan,
  • Abison Logeswaran,
  • Alexandra B. Sinclair and
  • Benjamin R. Wakerley

23 August 2021

Retinal migraine was first formally described in 1882. Various terms such as “ocular migraine” and “ophthalmic migraine” have since been used interchangeably in the literature. The lack of a consistent consensus-based definition has led to controvers...

(This article belongs to the Special Issue The Visual Aura in Migraine)
  • Article
  • Open Access
3 Citations
15,765 Views
23 Pages

25 January 2018

AMD does not just affect the retina. It severely affects people’s lives. Paying attention to this aspect will only become more important as the population ages and more otherwise healthy individuals become affected. This paper will discuss the need f...

(This article belongs to the Special Issue Age-Related Macular Degeneration)
  • Review
  • Open Access
97 Citations
14,826 Views
19 Pages

Eye Movements Actively Reinstate Spatiotemporal Mnemonic Content

  • Jordana S. Wynn,
  • Kelly Shen and
  • Jennifer D. Ryan

18 May 2019

Eye movements support memory encoding by binding distinct elements of the visual world into coherent representations. However, the role of eye movements in memory retrieval is less clear. We propose that eye movements play a functional role in retrie...

(This article belongs to the Special Issue Eye Movements and Visual Cognition)
  • Review
  • Open Access
28 Citations
14,643 Views
16 Pages

10 June 2021

Amblyopia is the most common cause of monocular poor vision affecting up to 3.7% of the global population. Classically, the first step in treatment has been optical correction, followed by patching and/or pharmacological treatment. However, this is a...

  • Review
  • Open Access
55 Citations
13,891 Views
12 Pages

Vision through Healthy Aging Eyes

  • Nir Erdinest,
  • Naomi London,
  • Itay Lavy,
  • Yair Morad and
  • Nadav Levinger

30 September 2021

As life expectancy grows, so too will the number of people adversely affected by age. Although it is acknowledged that many conditions and diseases are associated with age, this mini-review will present a current update of the various visual changes...

  • Article
  • Open Access
10 Citations
13,467 Views
10 Pages

Effects of Audiovisual Memory Cues on Working Memory Recall

  • Hilary C. Pearson and
  • Jonathan M. P. Wilbiks

19 March 2021

Previous studies have focused on topics such as multimodal integration and object discrimination, but there is limited research on the effect of multimodal learning in memory. Perceptual studies have shown facilitative effects of multimodal stimuli f...

(This article belongs to the Special Issue Sensory and Working Memory: Stimulus Encoding, Storage, and Retrieval)
  • Review
  • Open Access
10 Citations
13,421 Views
23 Pages

An Overview of the Penguin Visual System

  • Peter W. Hadden and
  • Jie Zhang

17 January 2023

Penguins require vision that is adequate for both subaerial and submarine environments under a wide range of illumination. Here we provide a structured overview of what is known about their visual system with an emphasis on how and how well they achi...

(This article belongs to the Special Issue Vision in Aquatic Environment)
  • Review
  • Open Access
10 Citations
13,296 Views
19 Pages

Critical Review of Visual Models for Police Use of Force Decision-Making

  • Paula M. Di Nota,
  • Peter Stoyko,
  • Jodie Jenkinson,
  • Evelyn C. Boychuk and
  • Judith P. Andersen

28 January 2021

Recent calls for widespread police reform include re-examination of existing training and practice surrounding the use of force (UOF, e.g., verbal and non-verbal communication, physical tactics, firearms). Visual models representing police UOF decisi...

  • Article
  • Open Access
9 Citations
13,074 Views
27 Pages

28 June 2022

The main purpose of this work is to explore the Gestalt principle of similarity and to demonstrate that the use of this term alone is not sufficient to understand the dynamics of grouping fully and correctly. More generally, this work aims to show th...

(This article belongs to the Special Issue Selected Papers from the Symposium on Perception and Cognition and Kanizsa Lecture 2021)
  • Review
  • Open Access
10 Citations
12,449 Views
24 Pages

Syndromic Retinitis Pigmentosa: A Narrative Review

  • Márta Janáky and
  • Gábor Braunitzer

20 January 2025

Retinitis pigmentosa (RP) encompasses inherited retinal dystrophies, appearing either as an isolated eye condition or as part of a broader systemic syndrome, known as syndromic RP. In these cases, RP includes systemic symptoms impacting other organs,...

(This article belongs to the Section Retinal Function and Disease)
  • Review
  • Open Access
121 Citations
12,327 Views
15 Pages

14 September 2020

Tilt and decentration of intraocular lenses (IOL) may occur secondary to a complicated cataract surgery or following an uneventful phacoemulsification. Although up to 2–3° tilt and a 0.2–0.3 mm decentration are common and clinically u...

  • Review
  • Open Access
59 Citations
12,315 Views
15 Pages

PreserFlo® MicroShunt: An Overview of This Minimally Invasive Device for Open-Angle Glaucoma

  • Gloria Gambini,
  • Matteo Mario Carlà,
  • Federico Giannuzzi,
  • Tomaso Caporossi and ,
  • Umberto De Vico,
  • Alfonso Savastano,
  • Antonio Baldascino,
  • Clara Rizzo,
  • Raphael Kilian and
  • Stanislao Rizzo
  • + 6 authors+ 1 author

9 February 2022

For moderate-to-severe glaucoma, trabeculectomy remains the “gold standard” intraocular pressure (IOP)-lowering treatment; nonetheless, this method requires extensive post-operative maintenance. Microinvasive glaucoma surgery (MIGS) treat...

  • Article
  • Open Access
4 Citations
11,956 Views
17 Pages

Differentiation of Types of Visual Agnosia Using EEG

  • Sarah M. Haigh,
  • Amanda K. Robinson,
  • Pulkit Grover and
  • Marlene Behrmann

18 December 2018

Visual recognition deficits are the hallmark symptom of visual agnosia, a neuropsychological disorder typically associated with damage to the visual system. Most research into visual agnosia focuses on characterizing the deficits through detailed beh...

(This article belongs to the Special Issue Visual Perception and Its Neural Mechanisms)
  • Article
  • Open Access
10 Citations
11,703 Views
13 Pages

The Sternberg Paradigm: Correcting Encoding Latencies in Visual and Auditory Test Designs

  • Julian Klabes,
  • Sebastian Babilon,
  • Babak Zandi and
  • Tran Quoc Khanh

The Sternberg task is a widely used tool for assessing the working memory performance in vision and cognitive science. It is possible to apply a visual or auditory variant of the Sternberg task to query the memory load. However, previous studies have...

(This article belongs to the Special Issue Sensory and Working Memory: Stimulus Encoding, Storage, and Retrieval)
  • Review
  • Open Access
11 Citations
11,577 Views
15 Pages

Visual Perception in Migraine: A Narrative Review

  • Nouchine Hadjikhani and
  • Maurice Vincent

28 April 2021

Migraine, the most frequent neurological ailment, affects visual processing during and between attacks. Most visual disturbances associated with migraine can be explained by increased neural hyperexcitability, as suggested by clinical, physiological...

(This article belongs to the Special Issue The Visual Aura in Migraine)
  • Article
  • Open Access
4 Citations
11,563 Views
26 Pages

The Colours of Octopus: Using Spectral Data to Measure Octopus Camouflage

  • Luis Nahmad-Rohen,
  • Yusuf H. Qureshi and
  • Misha Vorobyev

22 September 2022

No animal can so effectively camouflage in such a wide range of environments as the octopus. Thanks to their highly malleable skin, they are capable of adapting their body patterns to the brightness and texture of their immediate environment, and the...

(This article belongs to the Special Issue Vision in Aquatic Environment)
  • Review
  • Open Access
36 Citations
11,553 Views
17 Pages

The Limbal Niche and Regenerative Strategies

  • Sohil Amin,
  • Elmira Jalilian,
  • Eitan Katz,
  • Charlie Frank and ,
  • Ghasem Yazdanpanah,
  • Victor H. Guaiquil,
  • Mark I. Rosenblatt and
  • Ali R. Djalilian
  • + 3 authors+ 0 author

22 September 2021

The protective function and transparency provided by the corneal epithelium are dependent on and maintained by the regenerative capacity of limbal epithelial stem cells (LESCs). These LESCs are supported by the limbal niche, a specialized microenviro...

  • Review
  • Open Access
3 Citations
11,523 Views
17 Pages

21 December 2023

Faces and words are ever-present stimuli in social environments that require fine-grained, efficient discrimination of their constituents in order to acquire meaning. Provided that these stimuli share multiple characteristics, while simultaneously be...

  • Review
  • Open Access
26 Citations
11,038 Views
24 Pages

25 October 2019

The seminal model by Laurent Itti and Cristoph Koch demonstrated that we can compute the entire flow of visual processing from input to resulting fixations. Despite many replications and follow-ups, few have matched the impact of the original model&m...

(This article belongs to the Special Issue Eye Movements and Visual Cognition)
  • Review
  • Open Access
20 Citations
10,732 Views
22 Pages

Paracentral Acute Middle Maculopathy (PAMM) in Ocular Vascular Diseases—What We Know and Future Perspectives

  • Daniele Fumi,
  • Francesco Ruggeri,
  • Davide Fasciolo,
  • Elettra Antonello and ,
  • Giammarco Burtini and
  • Solmaz Abdolrahimzadeh
  • + 1 author+ 0 author

3 March 2025

Paracentral acute middle maculopathy (PAMM) is a macular condition primarily detected using optical coherence tomography (OCT) imaging. It presents as hyperreflective bands within the inner nuclear layer (INL) of the retina, often leading to localize...

  • Review
  • Open Access
41 Citations
10,565 Views
18 Pages

Intraocular Pressure Rise Linked to Silicone Oil in Retinal Surgery: A Review

  • Michele Nicolai,
  • Nicola Lassandro,
  • Alessandro Franceschi,
  • Alessandro Rosati and ,
  • Serena De Turris,
  • Paolo Pelliccioni,
  • Vittorio Pirani and
  • Cesare Mariotti
  • + 3 authors+ 0 author

13 August 2020

Silicone oil represents the main choice for intraocular tamponade in cases of complicated retinal detachment surgery. The intraocular pressure of an eye filled with silicone oil could increase, driven by a variety of different forces, according to se...

  • Review
  • Open Access
21 Citations
10,538 Views
32 Pages

24 May 2019

Autism spectrum disorder (ASD) is neurodevelopmental condition principally characterised by impairments in social interaction and communication, and repetitive behaviours and interests. This article reviews the eye movement studies designed to invest...

(This article belongs to the Special Issue Eye Movements and Visual Cognition)
  • Review
  • Open Access
23 Citations
10,408 Views
23 Pages

A Systematic Review of Clinical Practice Guidelines for Cataract: Evidence to Support the Development of the WHO Package of Eye Care Interventions

  • Justine H. Zhang,
  • Jacqueline Ramke,
  • Chan Ning Lee,
  • Iris Gordon and ,
  • Sare Safi,
  • Gareth Lingham,
  • Jennifer R. Evans and
  • Stuart Keel
  • + 3 authors+ 0 author

20 June 2022

The World Health Organization (WHO) is developing a Package of Eye Care Interventions (PECI) to facilitate the integration of eye care into Universal Health Coverage. This paper presents the results of a systematic review of clinical practice guideli...

  • Article
  • Open Access
7 Citations
10,054 Views
19 Pages

17 October 2017

To date, most studies involving in vivo electroretinography in mice are performed on steady state adapted animals. In this study, we focused on the dynamics of adaptation to high and low light levels in the mouse retina. Two flash electroretinogram (...

  • Review
  • Open Access
5 Citations
10,029 Views
9 Pages

5 November 2021

This paper outlines the historical development of the concept of the visual aura of migraine, from the first comprehensive published description by the physician Hubert Airy, in 1870. Airy’s description of the phenomenon he called “transient hemiopsi...

(This article belongs to the Special Issue The Visual Aura in Migraine)
  • Review
  • Open Access
18 Citations
9,807 Views
14 Pages

Transepithelial Photorefractive Keratectomy—Review

  • Christopher Way,
  • Mohamed Gamal Elghobaier and
  • Mayank A. Nanavaty

21 March 2024

The type and nature of refractive surgery procedures has greatly increased over the past few decades, allowing for almost all patient populations to be treated to extremely high satisfaction. Conventional photorefractive keratectomy involves the remo...

  • Article
  • Open Access
5 Citations
9,768 Views
12 Pages

18 November 2019

Two major uses of linear perspective are in planar paintings—the flat canvas is incongruent with the painted 3-D scene—and in forced perspectives, such as theater stages that are concave truncated pyramids, where the physical geometry and...

(This article belongs to the Special Issue Selected Papers from the Triestine 2018 Visual Science of Art Conference)
  • Article
  • Open Access
24 Citations
9,767 Views
17 Pages

Temporal Limits of Visual Motion Processing: Psychophysics and Neurophysiology

  • Bart G. Borghuis,
  • Duje Tadin,
  • Martin J.M. Lankheet,
  • Joseph S. Lappin and
  • Wim A. van de Grind

26 January 2019

Under optimal conditions, just 3–6 ms of visual stimulation suffices for humans to see motion. Motion perception on this timescale implies that the visual system under these conditions reliably encodes, transmits, and processes neural signals w...

(This article belongs to the Special Issue Visual Perception and Its Neural Mechanisms)
  • Review
  • Open Access
19 Citations
9,753 Views
17 Pages

Current Choroidal Imaging Findings in Central Serous Chorioretinopathy

  • Gideon Nkrumah,
  • Dmitrii S. Maltsev,
  • Paez-Escamilla A. Manuel,
  • Mohammed A. Rasheed and ,
  • Marianno Cozzi,
  • Alessandro Ivernizzi,
  • Marco Lupidi,
  • Sumit Randhir Singh and
  • Jay Chhablani
  • + 4 authors+ 0 author

16 October 2020

Background: Central serous chorioretinopathy (CSCR) is a chorioretinal disease affecting mostly middle age males. It is marked by the serous detachment of the neurosensory layer at the macula. This review of the literature provides a framework of the...

  • Article
  • Open Access
2 Citations
9,708 Views
8 Pages

Restricted Spatial Windows of Visibility in Myalgic Encephalomyelitis (ME)

  • Nadia S. Ahmed,
  • Irene Gottlob,
  • Frank A. Proudlock and
  • Claire V. Hutchinson

17 January 2018

Myalgic encephalomyelitis (ME) is a devastating disorder marked by debilitating fatigue. It not well understood and its diagnosis is controversial. It is very important therefore that significant clinical features are investigated. Visual symptoms in...

  • Case Report
  • Open Access
19 Citations
9,601 Views
6 Pages

11 May 2021

A case of an adult with anisometropic amblyopia who underwent a successful vision therapy program playing videogames in a virtual reality environment is described, reporting changes in conventional visual clinical data, as well as in brain activity....

  • Article
  • Open Access
19 Citations
9,522 Views
28 Pages

High-Accuracy Gaze Estimation for Interpolation-Based Eye-Tracking Methods

  • Fabricio Batista Narcizo,
  • Fernando Eustáquio Dantas dos Santos and
  • Dan Witzner Hansen

15 September 2021

This study investigates the influence of the eye-camera location associated with the accuracy and precision of interpolation-based eye-tracking methods. Several factors can negatively influence gaze estimation methods when building a commercial or of...

  • Review
  • Open Access
55 Citations
9,461 Views
19 Pages

30 December 2019

Current evidence supports the view that the visual pulvinar of primates consists of at least five nuclei, with two large nuclei, lateral pulvinar ventrolateral (PLvl) and central lateral nucleus of the inferior pulvinar (PIcl), contributing mainly to...

  • Review
  • Open Access
19 Citations
9,415 Views
26 Pages

13 March 2023

Corneal dystrophies are a group of non-inflammatory inherited disorders of the cornea. This review considers treatment options for epithelial-stromal and stromal corneal dystrophies: namely Reis–Bücklers, Thiel–Behnke, lattice, Avell...

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