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Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Therapeutic Mechanism of Nervous System Inflammation

edited by

Maria Anttonietta Panaro

and

Antonia Cianciulli

submission deadline 15 Sep 2024 | 4 articles | Viewed by 14144 | Submission Open

Keywords: neuroinflammation; neurodegeneration; therapy; drug target; cell signalling; cells of nervous system

(This special issue belongs to the Section Cells of the Nervous System)

Cellular and Molecular Mechanisms of Cancer Invasion and Metastasis

edited by

Wen G. Jiang

and

Qingping Dou

submission deadline 15 Sep 2024 | 7 articles | Viewed by 13509 | Submission Open

Keywords: cancer invasion; cancer metastasis; metastasis-related genes; metastasis biomarkers; novel targets; microenvironment; stromal factors

(This special issue belongs to the Section Cell Motility and Adhesion)

Rare Monogenic Diseases: Molecular Mechanism and Novel Therapies

edited by

Paweł Zapolnik

Antoni Pyrkosz

and

Artur Mazur

submission deadline 15 Sep 2024 | 2 articles | Viewed by 6263 | Submission Open

Keywords: rare diseases; monogenic diseases; genetics; molecular biology; molecular pathways; gene therapy; gene delivery; molecular medicine

(This special issue belongs to the Section Cellular Pathology)

Plant, Algae and Fungi Cell Biology: State-of-the-Art and Perspectives

edited by

Avtar K. Handa

and

Autar K. Mattoo

submission deadline 15 Sep 2024 | 3 articles | Viewed by 4152 | Submission Open

(This special issue belongs to the Section Plant, Algae and Fungi Cell Biology)

Endoplasmic Reticulum Stress in Neurodegenerative Diseases

edited by Dan Lindholm,

Mart Saarma

and Vera Kovaleva

submission deadline 15 Sep 2024 | 2 articles | Viewed by 3134 | Submission Open

Keywords: endoplasmic reticulum; ER stress; Parkinson’ s disease; Huntington’ s disease; amyotrophic lateral sclerosis; Alzheimer’ s disease; neurodegenerative disorders

(This special issue belongs to the Section Cells of the Nervous System)

From Mechanisms to Therapeutics: Wnt Signaling in Cancer—Second Edition

edited by

Anitha K. Shenoy

and

Liya Pi

submission deadline 15 Sep 2024 | 1 articles | Viewed by 1977 | Submission Open

Keywords: Wnt; β -catenin; development; homeostasis; cancer; cancer stem cells (CSC); targeted cancer therapy; canonical Wnt signaling; non-canonical Wnt signaling

(This special issue belongs to the Section Cell Signaling)

Advancing Human Cell Culture Towards More Physiological, Differentiated Tissues-Series II

edited by

Doris Wilflingseder

Bettina Seeger

, Anja Wilmes,

Michael J. Ausserlechner

and

Wilfried Posch

submission deadline 15 Sep 2024 | 1 articles | Viewed by 1609 | Submission Open

Keywords: human cell modeling; stem cells; gene expression analyses in 3D; phenotypic analyses in 3D; drug screening; toxicity testing; optimization of human cell models; challenges of 3D models; animal replacement; infection biology

(This special issue belongs to the Section Tissues and Organs)

Crosstalk of Autophagy and Apoptosis: Recent Advances

edited by

Maurizio Sorice

and

Valeria Manganelli

submission deadline 15 Sep 2024 | 1 articles | Viewed by 564 | Submission Open

Keywords: autophagy ; apoptosis ; cell signaling ; mitochondria ; MAMs ; lipid rafts ; cancer therapy ; autoimmunity

(This special issue belongs to the Section Autophagy)

Microproteins: From Identification to the Discovery of Their Functions

edited by

Bertrand Fabre

submission deadline 15 Sep 2024 | Viewed by 233 | Submission Open

Keywords: microproteins; short open reading frame-encoded peptides (SEPs); alternative proteins; functional characterization; mass spectrometry; transcriptomics; ribosome profiling; functional genomics; molecular mechanisms; cellular processes; signaling pathways; cellular homeostasis; protein– protein interactions

Mucosal Immunity and Epithelial Barrier Biology: From Tissue Homeostasis to Chronic Disease

edited by

Charles Pilette

, Marie Baeck and Peter Stärkel

submission deadline 20 Sep 2024 | 3 articles | Viewed by 3275 | Submission Open

Keywords: epithelial barrier; mucosal immunity; immune system; skin barrier; skin immunity; IgA; chronic disease; airways; respiratory; lung; gut; skin; therapeutic interventions

(This special issue belongs to the Section Cellular Immunology)

Endoplasmic Reticulum Stress Signaling Pathway: From Bench to Bedside

edited by Samuel Stephens and

Jianchao Zhang

submission deadline 20 Sep 2024 | Viewed by 229 | Submission Open

Keywords: ER stress; oxidative protein folding; ER redox; ER calcium homeostasis; UPR; diabetes; cancer; virus

(This special issue belongs to the Section Cell Signaling)

Harnessing the Immune System to Fight Pediatric Cancer—Second Edition

edited by

John M. Perry

submission deadline 20 Sep 2024 | Viewed by 212 | Submission Open

Keywords: immunotherapy; pediatric cancer; CAR T cells; immune checkpoint inhibitors; tumor microenvironment; therapy resistance; targeted therapy; adoptive cell transfer; stem-like T cells; bispecific antibodies; cancer vaccines

(This special issue belongs to the Section Cellular Immunology)

Advances in Vascular Aging

edited by Davide Agnoletti,

Andrea Grillo

and Filippo Valbusa

submission deadline 20 Sep 2024 | Viewed by 204 | Submission Open

Keywords: early vascular aging; arterial stiffness; central hemodynamics; endothelial function; inflammation; oxidative stress; cardiovascular risk

(This special issue belongs to the Section Cells of the Cardiovascular System)

Advances in Cellular and Molecular Treatment of Autoimmune Diseases

edited by

Panagiotis Athanassiou

Dimitrios P. Bogdanos

and

Ifigenia Kostoglou-Athanassiou

submission deadline 30 Sep 2024 | 6 articles | Viewed by 14441 | Submission Open

Keywords: autoimmune diseases; disease activity; TNFa inhibitors; tocilizumab; infliximab; golimumab; etanercept; JAK inhibitors; cellular targets; molecular targets

(This special issue belongs to the Section Cellular Immunology)

Genetics and Pathomechanisms of Amyotrophic Lateral Sclerosis (ALS)

edited by

Smita Saxena

submission deadline 30 Sep 2024 | 8 articles | Viewed by 13690 | Submission Open

Keywords: genetics of ALS/FTD; ER stress and UPR; mitochondria and mitochondrial-associated membranes; Ca2+ signaling; excitotoxicity/neuronal networks; synaptic dysfunction; therapeutic strategies

(This special issue belongs to the Section Cellular Pathology)

Mechanism of Cell Signaling during Eye Development and Diseases

edited by

Mehrnoosh Saghizadeh Ghiam

and

Vivien Coulson-Thomas

submission deadline 30 Sep 2024 | 8 articles | Viewed by 13008 | Submission Open

Keywords: cell signaling; ocular; eye disorders; Wnt signaling; TGF-β

(This special issue belongs to the Section Cell Signaling)

Male Reproductive Health and Infertility: A Look towards the Future II

edited by

Alice Luddi

Paola Piomboni

and

Rosanna Chianese

submission deadline 30 Sep 2024 | 6 articles | Viewed by 10233 | Submission Open

Keywords: sperm; male infertility; spermatogenesis; epigenetics; fertilization; exosomes; cell communication; oxidative stress; biomarkers

(This special issue belongs to the Section Reproductive Cells and Development)

Novel Therapeutic Targets and Approaches, Genetic Markers and Signaling Pathways in Neoplasms

edited by

Daria A. Chudakova

and

Kazuyuki Kitatani

submission deadline 30 Sep 2024 | 5 articles | Viewed by 8646 | Submission Open

Keywords: cancer; neoplasms; personalized medicine; genetic markers; next-generation sequencing (NGS); whole-genome sequencing; signaling pathways in cancer; novel therapeutic targets; drug development

(This special issue belongs to the Section Cell and Gene Therapy)

Understanding Spinal Cord Injury and Repair: From Molecules to Neurocircuits and Multimodal Prostheses

edited by

Yang D. Teng

submission deadline 30 Sep 2024 | 6 articles | Viewed by 7891 | Submission Open

(This special issue belongs to the Section Cells of the Nervous System)

Cancer-Related Signaling Cascades: Current Knowledge and Potential Therapeutic Targets

edited by

Takatsune Shimizu

and

Hideyuki Takeshima

submission deadline 30 Sep 2024 | 5 articles | Viewed by 7109 | Submission Open

Keywords: cancer signaling; crosstalk of signaling pathway; oncogenic activation; genetic alterations; epigenetic alterations; tumor microenvironment; therapeutic resistance

(This special issue belongs to the Section Cellular Pathology)

New Advances and Perspectives in Nanotechnology for the Treatment of Cancer Cells

edited by

Karuppusamy Shanmugapriya

submission deadline 30 Sep 2024 | 4 articles | Viewed by 6137 | Submission Open

Keywords: nanotechnology; immunotherapeutics; cancer biotherapeutics; proliferation; regulating factors; cell culture; biomedical application; nutraceuticals; cancer treatment

(This special issue belongs to the Section Cell Methods)

Stem and Progenitor Cells in Bone Regeneration

edited by

Sophie Verrier

submission deadline 30 Sep 2024 | 3 articles | Viewed by 5668 | Submission Open

Keywords: stem cells; progenitor cells; bone marrow stromal cells; bone healing and regeneration; tissue engineering; regenerative medicine; cells mobilization; intra-operative approaches; clinical use ethics/regulations burdens

(This special issue belongs to the Section Stem Cells)

Natural Products in Neurodegenerative Diseases: Current Trends and Future Perspectives

edited by

Anthony Tsarbopoulos

and Nikolaos Kokras

submission deadline 30 Sep 2024 | 2 articles | Viewed by 4303 | Submission Open

Keywords: bioactive compounds; protein aggregation processes in AD; cognitive; anxiolytic and antidepressant effects

(This special issue belongs to the Section Cells of the Nervous System)

Cellular and Molecular Basis of Alkaptonuria

edited by

and

submission deadline 30 Sep 2024 | 2 articles | Viewed by 4167 | Submission Open

Keywords: Alkaptonuria; AKU; pathophysiology; post-genomics; histopathology; bioinformatics

(This special issue belongs to the Section Cellular Pathology)

Molecular Insights into Corneal Wound Healing and Inflammation

edited by Tomas Blanco

submission deadline 30 Sep 2024 | 2 articles | Viewed by 3565 | Submission Open

Keywords: corneal wound healing; corneal transplantation; sensory nerves; neovascularization; fibrosis; growth factors; cytokines; neuropeptides

(This special issue belongs to the Section Cellular Immunology)

Inflammatory Pathways in Psychiatric Disorders

edited by Teresa Femenía

submission deadline 30 Sep 2024 | 1 articles | Viewed by 3564 | Submission Open

Keywords: inflammation; immune system; psychiatry; emotion; cognition

(This special issue belongs to the Section Cells of the Nervous System)

Cell Biology: State-of-the-Art and Perspectives in Italy 2024

edited by

Vincenzo Carafa

submission deadline 30 Sep 2024 | 5 articles | Viewed by 3213 | Submission Open

Molecular and Clinical Indicators of Cancer Management: Perspective on Cellular Therapy and Precision Medicines

edited by

Rick Francis Thorne

and

Ihtisham Bukhari

submission deadline 30 Sep 2024 | 1 articles | Viewed by 2984 | Submission Open

Keywords: cancer management; immunotherapy; precision medicine; anticancer drugs; cancer biomarkers; cancer development

(This special issue belongs to the Section Cellular Metabolism)

Resistance of Hematological Malignancies to CAR T Cell Therapy

edited by

Ali R. Jazirehi

submission deadline 30 Sep 2024 | 1 articles | Viewed by 2348 | Submission Open

Keywords: NHL; ALL; CAR T cell; immunotherapy; resistance; apoptosis

Cell Biology for Boron Neutron Capture Therapy (BNCT)

edited by

Wolfgang Sauerwein

Mitsuko Masutani

Lucie Sancey

and John Hopewell

submission deadline 30 Sep 2024 | 1 articles | Viewed by 2305 | Submission Open

Keywords: boron neutron capture therapy (BNCT); radiation biology; radiation oncology; drug development; imaging; targeted therapies; boron chemistry

Microbe–Heavy Metal Interactions

edited by

Timothy E. Ford

submission deadline 30 Sep 2024 | 1 articles | Viewed by 2261 | Submission Open

Keywords: horizontal gene transfer (HGT); gene duplication; natural selection; mutation; heavy metal resistance genes (MRGs); antibiotic resistance genes (ARGs); acid mine drainage (AMD); heavy metals; plasmids; mobile genetic elements (MGEs); transposons; extreme environments; bioremediation

The Role of Natural Extracts and Phytochemicals in the Treatment of Chronic Diseases

edited by

Daniela Carlisi

and

Anna De Blasio

submission deadline 30 Sep 2024 | 1 articles | Viewed by 1923 | Submission Open

The Mechanisms or Targets by Which the Microbiome Inhibits or Enhances Anti-inflammation or Tumor

edited by

Xiaonan Han

submission deadline 30 Sep 2024 | 1 articles | Viewed by 1351 | Submission Open

Keywords: microbiome; IBD; colon cancer; colitis-associated cancer; Th17 cells; cytokines; immune tolerance

(This special issue belongs to the Section Cellular Pathology)

Advances in DNA Repair Disorders Research: Molecular Mechanisms, Novel Therapies and Implications for Understanding Aging, Neurological Dysfunction and Cancer Progression

edited by Manuela Lanzafame

submission deadline 30 Sep 2024 | 1 articles | Viewed by 1214 | Submission Open

Keywords: DNA repair diseases; molecular mechanism; signaling pathway; therapies; aging; cancer; neurological dysfunction

(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)

New Concepts Relating Mesenchymal Tumors Based on Genetics and Epigenetics

edited by

Uta Flucke

submission deadline 30 Sep 2024 | 1 articles | Viewed by 1196 | Submission Open

Keywords: mesenchymal tumors; soft tissue; sarcoma; genetics; epigenetics

(This special issue belongs to the Section Cell Microenvironment)

Neurodegeneration Research Models: Advantages and Limitations

edited by

Morten Meyer

and Rohit Kumar

submission deadline 30 Sep 2024 | Viewed by 417 | Submission Open

Keywords: in vitro/vivo neurodegenerative disease models; computational neurodegenerative disease models; synucleinopathies; tauopathies; neurodegenerative disorders; neurodegeneration

(This special issue belongs to the Section Cells of the Nervous System)

Hepatology: From Natural History to Therapeutics—Second Edition

edited by

Alessandra Mangia

submission deadline 30 Sep 2024 | Viewed by 396 | Submission Open

Keywords: HCV; HBV; cirrhosis; HCC

(This special issue belongs to the Section Cellular Pathology)

Cellular and Molecular Mechanisms of Cancer Metastasis—2nd Edition

edited by

Ira-Ida Skvortsova

submission deadline 30 Sep 2024 | Viewed by 372 | Submission Open

(This special issue belongs to the Section Cellular Pathology)

Altered Central and Peripheral Inflammation in Depression

edited by

Miloš Mitić

and

Tamara Lazarević-Pašti

submission deadline 30 Sep 2024 | Viewed by 311 | Submission Open

Keywords: depression; inflammation; comorbidity; disease; therapy; immunopsychiatry

(This special issue belongs to the Section Cells of the Nervous System)

Membrane Damage and Repair in Organelles

edited by Yoko Shiba

submission deadline 30 Sep 2024 | Viewed by 270 | Submission Open

Keywords: membrane damage; organelle; pathogen; inorganic material; galectin

(This special issue belongs to the Section Intracellular and Plasma Membranes)

Synaptic Dysfunction in the Progressive Neurodegeneration of Alzheimer’s Disease and Related Dementia

edited by

Balaji Krishnan

submission deadline 30 Sep 2024 | Viewed by 256 | Submission Open

Keywords: synapses; dendrites; neurons; astrocytes; microglia; autophagy; reactive oxygen species (ROS); amyloidogenic proteins (including Tau; Aβ ; TDP-43; α -synuclein); AD/ADRD; traumatic brain injury (TBI)

(This special issue belongs to the Section Cellular Immunology)

Multidimensional Impact of Ionic Liquids on Cellular Dynamics: Integrating Cell Physiology, Molecular Biology, and Biophysics

edited by Gagandeep Singh and Meena Bisht

submission deadline 30 Sep 2024 | Viewed by 247 | Submission Open

Keywords: ionic liquids; cellular dynamics; multidisciplinary research; biophysical effects; biotechnological applications

Recent Advances in Metabolism and Oxidative Stress in Human Diseases 2.0

edited by

Isabella Panfoli

and Vanessa Cossu

submission deadline 30 Sep 2024 | Viewed by 192 | Submission Open

Keywords: antioxidant responses; redox balance; ROS; hematologic oncology; solid tumors; immune response; ATP; cancer cells; mitochondria-ER interactions; endoplasmic reticulum; glucose metabolism; inflammation; mitochondria; mitochondrial dynamics; autophagy; mitophagy; metabolic plasticity; metabolism

(This special issue belongs to the Section Cellular Metabolism)

Skeletal Muscle Differentiation and Epigenetics - Volume II

edited by

Rossella Maione

submission deadline 30 Sep 2024 | Viewed by 192 | Submission Open

Keywords: skeletal muscle differentiation and regeneration; epigenetic control of gene expression; chromatin structure and architecture; DNA methylation; histone modifications; nucleosome remodeling; noncoding RNAs; muscle regulatory factors; signal transduction

(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)

Unveiling Axon-Glia Communication in Health and Disease

edited by

Michela Rigoni

and Samuele Negro

submission deadline 30 Sep 2024 | Viewed by 188 | Submission Open

Keywords: glia-axon communication; oligodendrocytes; astrocytes; microglia; Schwann cells; enteric glia; neurodevelopment; neurodegeneration; neuroregeneration; cancer; pain; aging

(This special issue belongs to the Section Cells of the Nervous System)

Recent Advances of Apoptosis and Autophagy in Cardiovascular Diseases and Cancer

edited by Howard Chen, Vicky K. Yang and Asma Boukhalfa

submission deadline 30 Sep 2024 | Viewed by 164 | Submission Open

Keywords: autophagy; apoptosis; cardiovascular disease; cancer; cardio-oncology; cardioprotection; circulating biomarkers; 3D culture; animal models; clinical translation; drug development; metabolism; inflammation; signaling pathways

(This special issue belongs to the Section Cells of the Cardiovascular System)

Updates on Mesenchymal Stem Cells-Derived Extracellular Vesicles: Second Edition

edited by

Carl Randall Harrell

submission deadline 30 Sep 2024 | Viewed by 154 | Submission Open

Keywords: MSC-Exo-based tissue repair and regeneration; MSC-Exo-based immunomodulation; MSC-Exo-dependent therapy of inflammatory diseases; MSC-Exo-based therapy of degenerative diseases

(This special issue belongs to the Section Stem Cells)

Ion Channels in Cancer: An Update

edited by

Michael X. Zhu

and

Yong Zhou

submission deadline 30 Sep 2024 | Viewed by 145 | Submission Open

Keywords: ion channels; cancer therapy; cancer cell biology; mitogenic signaling; cancer signaling

(This special issue belongs to the Section Cell Proliferation and Division)

The Role of Adipose-Derived Stem Cells in Neural Regeneration

edited by Silvan Maximilian Klein, Alexandra M. Anker and Oliver Heinrich Felthaus

submission deadline 30 Sep 2024 | Viewed by 137 | Submission Open

Keywords: neural regeneration; mesenchymal stem cells; peripheral nerve injury; regenerative medicine; growth factors; cytokines; exosomes

(This special issue belongs to the Section Stem Cells)

Small Molecular Therapeutics Promoting Neuronal Plasticity, Hippocampal Learning, and Memory

edited by

Avik Roy

submission deadline 30 Sep 2024 | Viewed by 130 | Submission Open

Keywords: synaptic transmission; dendritic spines; metabotropic calcium influx; dendritic morphogenesis; small molecular therapeutics promoting neuronal plasticity

(This special issue belongs to the Section Cells of the Nervous System)

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