Special Issues

Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Muscle Research in Health and Disease—2nd Edition
edited by
submission deadline 20 Oct 2026 | 4 articles | Viewed by 9339 | Submission Open
Keywords: skeletal muscle; cardiac muscle; smooth muscle; myocyte; vascular smooth muscle cell; stem cell; development; homeostasis; regeneration; biomarker; therapeutic target
(This special issue belongs to the Section Tissues and Organs)
Vascular Biology: From Molecular Mechanisms to Precision Therapies
edited by Payaningal R. Somanath
submission deadline 20 Oct 2026 | Submission Open
Keywords: angiogenesis; endothelium; vascular permeability; blood– tissue barrier; organ injury
Caveolae Function in Cell Membrane Dynamics and Signal Transduction submission deadline 25 Oct 2026 | Viewed by 178 | Submission Open
Keywords: caveolae; caveolin and cavin proteins; plasma membrane organization; endocytosis and vesicular trafficking; mechanotransduction; lipid rafts and cholesterol metabolism; signal transduction; vascular biology and angiogenesis; cancer cell biology; membrane remodeling in disease
Cellular and Molecular Mechanisms in Bone and Cartilage Damage and Regeneration
edited by
submission deadline 31 Oct 2026 | 7 articles | Viewed by 13986 | Submission Open
Keywords: bone morphogenic proteins (BMPs); bone union with cell therapy; advances in stem cell therapies for fracture non-union and cartilage regeneration; novel cell-based therapies for cartilage repair; functional of collagen/PLA scaffolds in cartilage regeneration; regeneration and revascularization of bone osteonecrosis; evaluation of osteonecrosis regeneration with MRI and histology; and arteriography; identification and validation of new cartilage biomarkers; diaphyseal regeneration with callostasis; union with the membrane technique
(This special issue belongs to the Section Cellular Pathology)
Immunoregulation in Cardiovascular Disease
edited by
submission deadline 31 Oct 2026 | 1 articles | Viewed by 2238 | Submission Open
Keywords: cardiovascular disease (CVD); immunoregulation; inflammation; immune cells; immune mediators; immunomodulatory therapies; biomarkers; epigenetics; microbiome; cellular methods/technologies
Interactions Between Gut Microbiota and Epigenetic Markers in Health and Disease
edited by
submission deadline 31 Oct 2026 | Viewed by 127 | Submission Open
Keywords: gut microbiome; epigenetic marks; cancer; metabolic diseases; neuropsychiatric disorders; inflammatory diseases; infectious diseases; cardiovascular diseases; probiotics; prebiotics
(This special issue belongs to the Section Cell and Gene Therapy)
Neurotoxicity: Focusing on Molecular and Cellular Mechanisms
edited by , Manuel José Morales and
submission deadline 31 Oct 2026 | Viewed by 117 | Submission Open
Keywords: neurotoxicity; neuroinflammation; neurodegeneration; chemotherapy-induced neuropathy; neuroprotection; neuronal injury
Mechanobiological Regulation of Fibroblast-to-Myofibroblast Phenotype Transition
edited by Mirko D’urso and
submission deadline 31 Oct 2026 | Viewed by 95 | Submission Open
Keywords: fibroblasts; myofibroblasts; mechanotransduction; extracellular matrix; fibrosis; tissue remodeling; mechanobiology
(This special issue belongs to the Section Cell Microenvironment)
Nucleic Acids and Their Binding Partners: Structural and Mechanistic Insights
edited by
submission deadline 31 Oct 2026 | Viewed by 63 | Submission Open
Keywords: cryo-EM; NMR; AFM; molecular dynamics; nucleic acids; nucleic acid-protein complexes
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
Ovarian Tumors—Molecular Mechanisms, Cellular Dynamics, and Therapeutic Advances
edited by David Schweer, Joel Cardenas and
submission deadline 31 Oct 2026 | Viewed by 45 | Submission Open
Keywords: ovarian tumor biology; cellular signaling networks; genetic and epigenetic regulation; tumor microenvironment; cellular heterogeneity; single-cell and spatial omics; functional genomics; mechanisms of therapeutic resistance
(This special issue belongs to the Section Cellular Pathology)
Role of Inflammasomes in Neurological Disorders submission deadline 1 Nov 2026 | Viewed by 98 | Submission Open
Keywords: inflammasome; pyroptosis; caspase-1; ASC specks; IL-1beta; PANoptosis; CNS injury; neurodegenerative diseases; biomarkers; Alzheimer’ s disease; Parkinson’ s disease; multiple sclerosis; amyotrophic lateral sclerosis
(This special issue belongs to the Section Cellular Neuroscience)
Methane Biosynthesis
edited by , James Ferry and
submission deadline 10 Nov 2026 | Viewed by 274 | Submission Open
Keywords: methane; methanogenesis; methanogens; carbon cycle; gut microbiota; energy conservation; human diseases
Fibrosis in Chronic Inflammatory Diseases submission deadline 25 Nov 2026 | 8 articles | Viewed by 19771 | Submission Open
Keywords: fibrosis; fibroblasts; myofibroblasts; inflammation; molecular pathways; pathogenetic mechanisms; therapeutic targets
(This special issue belongs to the Section Cellular Pathology)
Cellular Differentiation in Health and Disease
edited by Christine K. C. Loo and
submission deadline 25 Nov 2026 | 1 articles | Viewed by 2861 | Submission Open
Keywords: cellular differentiation; tumour microenvironment; human development; regeneration/healing; cell signaling pathways; tumour differentiation
(This special issue belongs to the Section Cell Microenvironment)
Harnessing the Tumor Microenvironment and Signaling Pathways for Precision Cancer Therapy
edited by Behzad M. Toosi and
submission deadline 30 Nov 2026 | 2 articles | Viewed by 5446 | Submission Open
Keywords: tumor microenvironment (TME); signaling pathways; precision cancer therapy; immune evasion; metabolic pathways; tumor– stroma interactions; therapeutic targets; personalized medicine; cancer metastasis; molecular oncology
(This special issue belongs to the Section Cell Microenvironment)
How Does Gene Regulation Affect Cancer Development? submission deadline 30 Nov 2026 | Viewed by 329 | Submission Open
Keywords: cancer; mutation; transcription factor; non-coding RNA; micro-RNA; gene regulation; histones; gene promoters; anticancer drugs
(This special issue belongs to the Section Cell Microenvironment)
Molecular Mechanisms of Asthmatic Airway Inflammation
edited by
submission deadline 30 Nov 2026 | Viewed by 94 | Submission Open
Keywords: asthma; airway inflammation; airway smooth muscle; airway remodeling; immune signaling; cytokines and chemokines; cell signaling; inflammatory mechanisms; airway epithelial cells
(This special issue belongs to the Section Cellular Immunology)
Mechanisms of Transcriptional Regulation in Disease: From Chromatin Dynamics to Therapeutic Innovation
edited by Valentina Caputo and Joana R. Costa
submission deadline 30 Nov 2026 | Viewed by 84 | Submission Open
Keywords: transcription regulation; epigenomics; multi-omics; non-coding genome; chromatin architecture/dynamics; enhancers
(This special issue belongs to the Section Cell and Gene Therapy)
Targeting Hallmarks of Cancer submission deadline 25 Dec 2026 | 3 articles | Viewed by 6887 | Submission Open
Keywords: epigenetic regulators; organotypic culture models; anticancer drugs; hallmarks of cancer
Cellular Pathology: Emerging Discoveries and Perspectives in the USA submission deadline 31 Dec 2026 | 2 articles | Viewed by 8985 | Submission Open
Keywords: cellular pathology; diseases; mechanisms
(This special issue belongs to the Section Cellular Pathology)
New Advances in Tissue Engineering and Regeneration submission deadline 25 Jan 2027 | 2 articles | Viewed by 3254 | Submission Open
Keywords: tissue regeneration; tissue engineering; regenerative medicine; musculoskeletal tissues; biomaterials; stem cells; 3D bioprinting; scaffold design; cell therapy; organoids; translational research
(This special issue belongs to the Section Tissues and Organs)
Current Status and Future Challenges of Liquid Biopsy—2nd Edition
edited by and
submission deadline 1 Oct 2027 | Viewed by 285 | Submission Open
Keywords: minimal residual disease (MRD); ctDNA; cfDNA; heterogeneity; comprehensive genomic profiling; biomarker; diagnosis; personalization; prognostic marker
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