Special Issues

Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Role of Endothelial Progenitor Cells in Vascular Dysfunction submission deadline 30 Sep 2026 | Viewed by 35 | Submission Open
Keywords: cardiovascular diseases; endothelial progenitor cells; vasculogenesis; angiogenesis; inflammation; oxidative stress; cellular senescence; developmental programming; cellular therapy
Sickle Cell Disease: Pathogenesis and Therapies
edited by and Geoffrey Cheminet
submission deadline 30 Sep 2026 | Submission Open
Keywords: sickle cell disease; erythrocyte sickling; chronic inflammation; endothelial dysfunction; hematopoietic stem cell transplantation
(This special issue belongs to the Section Cellular Pathology)
mRNA Regulation in Endoplasmic Reticulum Stress and Protein Homeostasis submission deadline 30 Sep 2026 | Submission Open
Keywords: mRNA; secondary structures of mRNA; upstream open reading frames (uORFs); biomarkers; endoplasmic reticulum stress; unfolded protein response; protein homeostasis
(This special issue belongs to the Section Cell and Gene Therapy)
Caveolae Function in Cell Membrane Dynamics and Signal Transduction submission deadline 25 Oct 2026 | Viewed by 131 | Submission Open
Keywords: caveolae; caveolin and cavin proteins; plasma membrane organization; endocytosis and vesicular trafficking; mechanotransduction; lipid rafts and cholesterol metabolism; signal transduction; vascular biology and angiogenesis; cancer cell biology; membrane remodeling in disease
Neurotoxicity: Focusing on Molecular and Cellular Mechanisms
edited by , Manuel José Morales and
submission deadline 31 Oct 2026 | Viewed by 65 | Submission Open
Keywords: neurotoxicity; neuroinflammation; neurodegeneration; chemotherapy-induced neuropathy; neuroprotection; neuronal injury
Interactions Between Gut Microbiota and Epigenetic Markers in Health and Disease
edited by
submission deadline 31 Oct 2026 | Viewed by 2 | Submission Open
Keywords: gut microbiome; epigenetic marks; cancer; metabolic diseases; neuropsychiatric disorders; inflammatory diseases; infectious diseases; cardiovascular diseases; probiotics; prebiotics
(This special issue belongs to the Section Cell and Gene Therapy)
Mechanobiological Regulation of Fibroblast-to-Myofibroblast Phenotype Transition
edited by Mirko D’urso and
submission deadline 31 Oct 2026 | Submission Open
Keywords: fibroblasts; myofibroblasts; mechanotransduction; extracellular matrix; fibrosis; tissue remodeling; mechanobiology
(This special issue belongs to the Section Cell Microenvironment)
Role of Inflammasomes in Neurological Disorders submission deadline 1 Nov 2026 | Viewed by 29 | Submission Open
Keywords: inflammasome; pyroptosis; caspase-1; ASC specks; IL-1beta; PANoptosis; CNS injury; neurodegenerative diseases; biomarkers; Alzheimer’ s disease; Parkinson’ s disease; multiple sclerosis; amyotrophic lateral sclerosis
(This special issue belongs to the Section Cellular Neuroscience)
Harnessing the Tumor Microenvironment and Signaling Pathways for Precision Cancer Therapy
edited by Behzad M. Toosi and
submission deadline 30 Nov 2026 | 2 articles | Viewed by 5091 | Submission Open
Keywords: tumor microenvironment (TME); signaling pathways; precision cancer therapy; immune evasion; metabolic pathways; tumor– stroma interactions; therapeutic targets; personalized medicine; cancer metastasis; molecular oncology
(This special issue belongs to the Section Cell Microenvironment)
Mechanisms of Transcriptional Regulation in Disease: From Chromatin Dynamics to Therapeutic Innovation
edited by Valentina Caputo and Joana R. Costa
submission deadline 30 Nov 2026 | Viewed by 11 | Submission Open
Keywords: transcription regulation; epigenomics; multi-omics; non-coding genome; chromatin architecture/dynamics; enhancers
(This special issue belongs to the Section Cell and Gene Therapy)
Current Status and Future Challenges of Liquid Biopsy—2nd Edition
edited by and
submission deadline 1 Oct 2027 | Viewed by 196 | Submission Open
Keywords: minimal residual disease (MRD); ctDNA; cfDNA; heterogeneity; comprehensive genomic profiling; biomarker; diagnosis; personalization; prognostic marker
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