Cells

Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Nucleic Acids and Their Binding Partners: Structural and Mechanistic Insights

edited by

Rashmi Panigrahi

submission deadline 31 Oct 2026 | Viewed by 61 | Submission Open

Keywords: cryo-EM; NMR; AFM; molecular dynamics; nucleic acids; nucleic acid-protein complexes

(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)

Ovarian Tumors—Molecular Mechanisms, Cellular Dynamics, and Therapeutic Advances

edited by David Schweer, Joel Cardenas and

Delia Mezzanzanica

submission deadline 31 Oct 2026 | Viewed by 41 | Submission Open

Keywords: ovarian tumor biology; cellular signaling networks; genetic and epigenetic regulation; tumor microenvironment; cellular heterogeneity; single-cell and spatial omics; functional genomics; mechanisms of therapeutic resistance

(This special issue belongs to the Section Cellular Pathology)

Role of Inflammasomes in Neurological Disorders

edited by

Juan Pablo de Rivero Vaccari

submission deadline 1 Nov 2026 | Viewed by 97 | Submission Open

Keywords: inflammasome; pyroptosis; caspase-1; ASC specks; IL-1beta; PANoptosis; CNS injury; neurodegenerative diseases; biomarkers; Alzheimer’ s disease; Parkinson’ s disease; multiple sclerosis; amyotrophic lateral sclerosis

(This special issue belongs to the Section Cellular Neuroscience)

Methane Biosynthesis

edited by

Divya Prakash

, James Ferry and

Shikha Singh Chauhan

submission deadline 10 Nov 2026 | Viewed by 272 | Submission Open

Keywords: methane; methanogenesis; methanogens; carbon cycle; gut microbiota; energy conservation; human diseases

Fibrosis in Chronic Inflammatory Diseases

edited by

Mirko Manetti

Irene Rosa

and

Eloisa Romano

submission deadline 25 Nov 2026 | 8 articles | Viewed by 19701 | Submission Open

Keywords: fibrosis; fibroblasts; myofibroblasts; inflammation; molecular pathways; pathogenetic mechanisms; therapeutic targets

(This special issue belongs to the Section Cellular Pathology)

Cellular Differentiation in Health and Disease

edited by Christine K. C. Loo and

Grant A. Ramm

submission deadline 25 Nov 2026 | 1 articles | Viewed by 2842 | Submission Open

Keywords: cellular differentiation; tumour microenvironment; human development; regeneration/healing; cell signaling pathways; tumour differentiation

(This special issue belongs to the Section Cell Microenvironment)

Harnessing the Tumor Microenvironment and Signaling Pathways for Precision Cancer Therapy

edited by Behzad M. Toosi and

Andrew Freywald

submission deadline 30 Nov 2026 | 2 articles | Viewed by 5425 | Submission Open

Keywords: tumor microenvironment (TME); signaling pathways; precision cancer therapy; immune evasion; metabolic pathways; tumor– stroma interactions; therapeutic targets; personalized medicine; cancer metastasis; molecular oncology

(This special issue belongs to the Section Cell Microenvironment)

How Does Gene Regulation Affect Cancer Development?

edited by

Ru Chih C. Huang

and

Kotohiko Kimura

submission deadline 30 Nov 2026 | Viewed by 328 | Submission Open

Keywords: cancer; mutation; transcription factor; non-coding RNA; micro-RNA; gene regulation; histones; gene promoters; anticancer drugs

(This special issue belongs to the Section Cell Microenvironment)

Molecular Mechanisms of Asthmatic Airway Inflammation

edited by

Pawan Sharma

submission deadline 30 Nov 2026 | Viewed by 92 | Submission Open

Keywords: asthma; airway inflammation; airway smooth muscle; airway remodeling; immune signaling; cytokines and chemokines; cell signaling; inflammatory mechanisms; airway epithelial cells

(This special issue belongs to the Section Cellular Immunology)

Mechanisms of Transcriptional Regulation in Disease: From Chromatin Dynamics to Therapeutic Innovation

edited by Valentina Caputo and Joana R. Costa

submission deadline 30 Nov 2026 | Viewed by 78 | Submission Open

Keywords: transcription regulation; epigenomics; multi-omics; non-coding genome; chromatin architecture/dynamics; enhancers

(This special issue belongs to the Section Cell and Gene Therapy)

Targeting Hallmarks of Cancer

edited by

Carlos Pérez Plasencia

submission deadline 25 Dec 2026 | 3 articles | Viewed by 6871 | Submission Open

Keywords: epigenetic regulators; organotypic culture models; anticancer drugs; hallmarks of cancer

Cellular Pathology: Emerging Discoveries and Perspectives in the USA

edited by

Mohammed S. Razzaque

submission deadline 31 Dec 2026 | 2 articles | Viewed by 8915 | Submission Open

Keywords: cellular pathology; diseases; mechanisms

(This special issue belongs to the Section Cellular Pathology)

New Advances in Tissue Engineering and Regeneration

edited by

Giorgia Borciani

and

Giorgia Montalbano

submission deadline 25 Jan 2027 | 2 articles | Viewed by 3203 | Submission Open

Keywords: tissue regeneration; tissue engineering; regenerative medicine; musculoskeletal tissues; biomaterials; stem cells; 3D bioprinting; scaffold design; cell therapy; organoids; translational research

(This special issue belongs to the Section Tissues and Organs)

Current Status and Future Challenges of Liquid Biopsy—2nd Edition

edited by

Kenichi Suda

and

Shuta Ohara

submission deadline 1 Oct 2027 | Viewed by 283 | Submission Open

Keywords: minimal residual disease (MRD); ctDNA; cfDNA; heterogeneity; comprehensive genomic profiling; biomarker; diagnosis; personalization; prognostic marker

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