Skeletal Muscle Aging and Regeneration: Mitochondrial Health, Molecular Signaling, and Therapeutic Interventions
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 31 May 2026 | Viewed by 115
Special Issue Editor
2. Laboratory of Muscle Biology and Sarcopenia, College of Health Professions, University of Tennessee Health Science Center, Memphis, TN, USA
3. Center for Muscle, Metabolism and Neuropathology, College of Health Professions, University of Tennessee Health Science Center, Memphis, TN, USA
4. The Tennessee Institute of Regenerative Medicine, Memphis, TN, USA
Interests: sarcopenia; muscle regeneration; muscle wasting; apoptosis; mitochondria; muscle stem cells; muscle strength; muscle fatigue; aging
Special Issue Information
Dear Colleagues,
The age-related decline in skeletal muscle health is a major cause of reduced mobility and disability. A critical step toward developing effective interventions is a deeper understanding of the underlying molecular mechanisms.
This decline is characterized by a progressive loss of muscle mass and function, driven largely by mitochondrial dysfunction and impaired regenerative capacity. This Special Issue will explore how mitochondrial integrity, quality control, and associated signaling pathways dictate cellular function and repair processes. We invite the submission of original research and review articles. This Special Issue will elucidate these fundamental mechanisms and translate these insights into innovative strategies to counteract muscle wasting and enhance regeneration in aging populations.
Prof. Dr. Stephen E. Alway
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- aging
- skeletal muscle
- regeneration
- satellite cells
- muscle stem cells
- muscle wasting
- mitochondria
- fibro-adipogenic progenitor cells
- repair
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