Molecular Bases Underlying Early Embryonic Development in Mammals
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Reproductive Cells and Development".
Deadline for manuscript submissions: 31 May 2026 | Viewed by 167
Special Issue Editors
Interests: fertility molecular biomarkers; gene expression; embryo development; miRNA expression; embryogenesis; cancer chemotherapy; enteric nervous system; colorectal cancer
Interests: reproductive physiology; gene expression; embryo development; miRNA expression; embryogenesis; cancer chemotherapy; central nervous system; neurotoxicity
Special Issue Information
Dear Colleagues,
The early stages of mammalian embryonic development are characterized by a series of finely coordinated molecular and cellular events that determine the success of implantation and subsequent growth. Small alterations in these early processes can lead to impaired embryo viability and development. Understanding the molecular bases of these mechanisms is essential to identifying mechanisms underlying reproductive success and to reveal how disturbances lead to developmental defects or pregnancy loss.
Recent advances in molecular and cell biology are helping to uncover how gene expression, epigenetic regulation, and signaling pathways interact with metabolism and oxidative balance to support cell division, differentiation, and communication during early development. This Special Issue aims to gather original research and review articles that advance our understanding of the molecular and cellular mechanisms that affect the first stages of mammalian embryonic development. By integrating molecular, metabolic, and physiological perspectives, this Special Issue aims to integrate fundamental and translational insights, contributing to a deeper understanding of the factors that determine embryonic health and developmental success. We encourage researchers to submit manuscripts sharing molecular signalling, metabolic pathways, mitochondrial function, oxidative stress, or experimental models related to early embryos and developmental competence.
Dr. Rebeca González Fernández
Prof. Dr. Julio Ávila Marrero
Dr. Angela Palumbo
Guest Editors
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- embryonic development
- early embryogenesis
- gene expression
- miRNA profile
- reproductive physiology
- cell signalling
- embryo quality
- developmental competence
- in vitro embryo culture
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