Inflammatory Signaling and Vascular Dysfunction in Atherosclerosis
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 31 May 2026 | Viewed by 148
Special Issue Editors
Interests: endothelial-to-mesenchymal transition (EndMT); atherosclerosis; atherosclerotic diseases; inflammation; cell signaling; single-cell sequencing
Special Issues, Collections and Topics in MDPI journals
Interests: endothelial cells; monocytes; atherosclerosis; thrombosis; sterile inflammation; G protein-coupled receptor (GPCR); cell signal transduction; metformin
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Atherosclerosis, a chronic inflammatory disease of the arterial wall, is driven by complex interactions between vascular dysfunction and aberrant immune responses. Endothelial cell activation, monocyte recruitment, and phenotypic switching are critical events orchestrated by an intricate network of intracellular signaling pathways.
This Special Issue aims to highlight cutting-edge research that elucidates the molecular mechanisms linking inflammatory signaling to vascular pathology in atherosclerosis. We welcome original research and review articles that explore topics including, but not limited to, the following: the role of GPCR signaling in leukocyte–endothelial interactions; mechanistic insights into EndMT in plaque stability; novel signaling pathways in sterile inflammation; the impact of metabolic interventions on vascular inflammation; and applications of single-cell omics to decipher cellular crosstalk in the atherosclerotic niche. By integrating insights from vascular biology and immunology, this Special Issue seeks to identify novel therapeutic targets for combating atherosclerotic diseases.
Dr. Qianman Peng
Prof. Dr. Jianzhong Shen
Guest Editors
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- inflammation in atherosclerosis
- atherothrombosis
- cell signaling
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