Special Issues

Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Therapeutic Potentials of Adipose-Derived Stem Cells
edited by
submission deadline 15 Dec 2024 | 2 articles | Viewed by 5191 | Submission Open
Keywords: adipose stem cells; tissue regeneration; clinical applications
(This special issue belongs to the Section Tissues and Organs)
Role of Microenvironment in the Control of Cell Proliferation, Death, and Autophagy submission deadline 15 Dec 2024 | 2 articles | Viewed by 4984 | Submission Open
(This special issue belongs to the Section Cell Microenvironment)
Recent Advances in Tumor Immunological Microenvironment Research
edited by Yue Sun
submission deadline 15 Dec 2024 | 1 articles | Viewed by 2137 | Submission Open
Keywords: tumor immune microenvironment; cancer immunotherapy; immune cells; immunosuppression; immune cell infiltration
(This special issue belongs to the Section Cell Microenvironment)
Lipids and Lipidomics in Neurodegenerative Diseases
edited by and Catherine Malaplate
submission deadline 15 Dec 2024 | 1 articles | Viewed by 1992 | Submission Open
Keywords: lipids; lipidomics; neurodegenerative disease diagnosis; prevention; or treatment; cellular and molecular mechanisms
(This special issue belongs to the Section Cells of the Nervous System)
Advances in Melanoma Immunotherapy
edited by Jeffrey D. McBride
submission deadline 15 Dec 2024 | 1 articles | Viewed by 1568 | Submission Open
Keywords: melanoma immunotherapy; therapeutic targets; immune modulation; oncolytic viruses; checkpoint inhibitors; cancer vaccines; tumor biomarkers; tumor microenvironment; treatment strategies
(This special issue belongs to the Section Cellular Immunology)
Advances in Muscle Stem Cells and Development
edited by Xuesong Feng
submission deadline 15 Dec 2024 | 1 articles | Viewed by 1493 | Submission Open
Keywords: muscle stem cells; development; myogenesis; regeneration; myopathies
(This special issue belongs to the Section Cell and Gene Therapy)
The Role of Hypoxia-Inducible Factors (HIFs) in Human Diseases submission deadline 15 Dec 2024 | Viewed by 232 | Submission Open
Keywords: oxygen; hypoxia; HIF; transcription; cancer; anemia; ischemia; cardiovascular disorders; erythrocytosis; pulmonary hypertension
(This special issue belongs to the Section Cellular Pathology)
New Advances in Neuroinflammation
edited by and Michael Breckwoldt
submission deadline 20 Dec 2024 | 12 articles | Viewed by 28439 | Submission Open
Keywords: neuroinflammation; biomarkers; neurodegeneration; microglia; astrocytes; oligodendrocytes; neurological diseases; blood-brain barrier; imaging
(This special issue belongs to the Section Cells of the Nervous System)
Melanoma: From Molecular Mechanisms to Therapeutic Opportunities—Series 2 submission deadline 20 Dec 2024 | 3 articles | Viewed by 4675 | Submission Open
Keywords: melanomagenesis; treatment response; signal transduction; melanoma initiating cells; drug resistance; invasiveness; immune evasion; metastasis; MAPK pathway; PI3K/AKT survival pathways; MEKi; BRAFi; trametinib; dabrafenib; immunotherapies
(This special issue belongs to the Section Cellular Pathology)
Molecular Mechanisms of Tumor Pathogenesis
edited by and Alessandro Lavoro
submission deadline 20 Dec 2024 | 4 articles | Viewed by 4531 | Submission Open
Keywords: cancer; therapeutic targets; biomarkers; epigenetics; DNA methylation; microRNAs; somatic mutations; germline mutations; chromatin remodeling; histone modifications
(This special issue belongs to the Section Cellular Pathology)
Identifying Molecular or Cellular Level Pathomechanisms for Possible Therapeutic/Neuroprotective Interventions in Traumatic Brain Injury
edited by Krisztina Amrein and
submission deadline 20 Dec 2024 | 2 articles | Viewed by 3568 | Submission Open
Keywords: traumatic brain injury; head injury; clinical study; experimental model; neuroprotective intervention; therapy; pathomechanism; molecular; cellular
(This special issue belongs to the Section Cellular Pathology)
Liver Constituent Cells: Their Niche, Close Intercellular Relationship and Crosstalk with the Extracellular Environment—Current and Future Perspectives (2nd Edition) submission deadline 20 Dec 2024 | 2 articles | Viewed by 3015 | Submission Open
Keywords: chronic liver diseases; liver microcirculatory milieu; liver sinusoidal endothelial cells (LSECs); hepatic stellate cells (HSCs); Kupffer cells; hepatocytes; cholangiocytes; sinusoid capillarization; Disse space
(This special issue belongs to the Section Tissues and Organs)
Molecular Studies of Aging and Anti-Aging Strategies in Animals and Humans
edited by Paweł Kordowitzki
submission deadline 20 Dec 2024 | 2 articles | Viewed by 2346 | Submission Open
Keywords: aging; anti-aging; humans; animals; epigenetic clocks; DNA methylation; longevity
(This special issue belongs to the Section Cellular Aging)
Advance in Spermatogenesis
edited by and Changmin Niu
submission deadline 20 Dec 2024 | 2 articles | Viewed by 1899 | Submission Open
Keywords: spermatogenesis; mitosis; meiosis; spermiogenesis; omics; organoid culture; infertility; contraception
(This special issue belongs to the Section Reproductive Cells and Development)
Molecular Mechanism of Liver Transplantation
edited by Carmen Peralta and Juan Carlos Cutrin
submission deadline 20 Dec 2024 | 1 articles | Viewed by 1798 | Submission Open
Keywords: liver transplantation; ischemia-reperfusion injury; signaling pathways; graft dysfunction; sterile inflammation; liver regeneration; fatty grafts; normothermic machine perfusion; defatting strategies
(This special issue belongs to the Section Tissues and Organs)
Molecular Pathways and Potential Therapeutic Targets of Vascular Dysfunction submission deadline 20 Dec 2024 | 1 articles | Viewed by 1199 | Submission Open
Keywords: vascular dysfunction; endothelial dysfunction; vascular remodeling; arterial stiffness; vascular signaling; new vascular targets
(This special issue belongs to the Section Cells of the Cardiovascular System)
Molecular Advances in Prenatal Exposure to Environmental Toxicants submission deadline 20 Dec 2024 | 1 articles | Viewed by 1106 | Submission Open
Keywords: prenatal exposures; toxicogenomics; epigenomics; placenta; perinatal outcomes; neurodevelopmental outcomes; respiratory outcomes
Understanding Cellular, Molecular, and Functional Specificity, Heterogeneity, and Diversity of the Endocannabinoid System
edited by and
submission deadline 20 Dec 2024 | 1 articles | Viewed by 964 | Submission Open
Keywords: molecular markers; brain circuits; development; neural plasticity; neurological disorders; immune diseases; cancer; cluster analysis
Extracellular Vesicles and Drug Delivery System for Developing Cancer Therapeutics
edited by
submission deadline 20 Dec 2024 | 1 articles | Viewed by 879 | Submission Open
Keywords: extracellular vesicles; drug delivery; cancer therapeutics  
Molecular and Cellular Mechanisms of Neuro-Cardiac Interactions submission deadline 20 Dec 2024 | Viewed by 469 | Submission Open
Keywords: cardiac autonomic nervous system; cell-cell communication in the heart; cardiac response to stresses
(This special issue belongs to the Section Cellular Pathology)
Molecular and Cellular Mechanisms of Central Nervous System Autoimmunity submission deadline 20 Dec 2024 | Viewed by 299 | Submission Open
Keywords: neuroimmunity; central nervous system; autoimmunity; immune tolerance; multiple sclerosis; antibody-mediated autoimmunity; cellular immunology; neuroinflammation
(This special issue belongs to the Section Cells of the Nervous System)
Advances in Obesity-Linked Breast Cancer Research
edited by and Ashutosh Yende
submission deadline 20 Dec 2024 | Viewed by 204 | Submission Open
Keywords: breast cancer; obesity; tumor microenvironment; inflammation; therapy resistance; immunotherapy; adipocytes; BMI; weight loss
Cellular Therapy of Leukemia
edited by Jeffrey Pu
submission deadline 20 Dec 2024 | Viewed by 189 | Submission Open
Keywords: immunotherapy; leukemia; lymphoma; target therapy; biomarker
(This special issue belongs to the Section Cellular Pathology)
Molecular and Cellular Basis of Sleep Disorders
edited by
submission deadline 25 Dec 2024 | 2 articles | Viewed by 3612 | Submission Open
Keywords: intermittent hypoxia; sleep fragmentation; sleep deprivation; OSA animal model; biomarkers
(This special issue belongs to the Section Cellular Pathology)
Nonalcoholic Fatty Liver Disease: From Mechanisms to Therapeutics
edited by and Alessandra Scamporrino
submission deadline 25 Dec 2024 | 2 articles | Viewed by 3358 | Submission Open
Keywords: NAFL; NASH; cirrhosis; molecular mechanisms; liver; gut; metabolic tissues
(This special issue belongs to the Section Cellular Metabolism)
Cellular Glycosphingolipids in Human Disease submission deadline 25 Dec 2024 | 1 articles | Viewed by 2260 | Submission Open
Keywords: glycosphingolipid; cancer; sphingolipid; signal transduction; epithelial to mesenchymal; ceramide; microdomain; chemoresistance; glucosylceramide; ganglioside; globoside; lactoside; neolactoside; sulfatide; GSL
(This special issue belongs to the Section Cellular Pathology)
Progress in Cancer Immunotherapies
edited by and Phuc Loi Luu
submission deadline 25 Dec 2024 | 1 articles | Viewed by 2036 | Submission Open
Keywords: cancer immunotherapy; immune checkpoint inhibitors; personalized immunotherapy; tumor microenvironment; biomarkers in immunotherapy
(This special issue belongs to the Section Cellular Immunology)
Novel Insights into Molecular Mechanisms and Therapy of Soft Tissue Sarcomas submission deadline 25 Dec 2024 | 1 articles | Viewed by 979 | Submission Open
Keywords: soft tissue sarcoma; molecular genetics; epigenetics  ; gene expression  ; ncRNA  ; post-transcriptional regulations  ; post-translational modifications  ; targeted therapy  ; drug resistance  ; molecular biomarkers
(This special issue belongs to the Section Tissues and Organs)
Mitochondrial Dysfunction in Neurodegeneration: A Translational Perspective
edited by Hemendra Vekaria
submission deadline 25 Dec 2024 | Viewed by 400 | Submission Open
Keywords: mitochondrial dysfunction; traumatic brain injury; secondary damage; bioenergetics
(This special issue belongs to the Section Cells of the Nervous System)
Cellular Mechanisms of Therapy Resistance and Metastasis in Breast Cancer
edited by Naseem Akhter and Sajad Ahmad Dar
submission deadline 25 Dec 2024 | Viewed by 300 | Submission Open
Keywords: single-cell sequencing; tumor microenvironment; immunotherapies; precision medicine; therapy resistance mechanisms
(This special issue belongs to the Section Cellular Pathology)
Therapeutic Applications of Magnetotactic Bacteria and Magnetosomes: State-of-the-Art and Perspectives
edited by
submission deadline 25 Dec 2024 | Viewed by 144 | Submission Open
Keywords: biomedical applications; biotechnology; magnetite nanocrystals; magnetosomes; magnetotactic bacteria; nanotechnology; nanotargeting
(This special issue belongs to the Section Cellular Biophysics)
Cellular and Molecular Mechanisms in Gynecological Disorders
edited by
submission deadline 30 Dec 2024 | 3 articles | Viewed by 5677 | Submission Open
Keywords: uterus; ovary; breast; cervix; cancer; endometriosis; leiomyoma; adenomyosis; polycystic ovary syndrome; female infertility; pathways; cell atlas; transcriptome; epigenome
(This special issue belongs to the Section Reproductive Cells and Development)
Modeling Developmental Processes and Disorders in Zebrafish submission deadline 31 Dec 2024 | 10 articles | Viewed by 28323 | Submission Open
(This special issue belongs to the Section Cellular Biophysics)
Role of Vascular Smooth Muscle Cells in Cardiovascular Disease
edited by and Claire Holden
submission deadline 31 Dec 2024 | 9 articles | Viewed by 26073 | Submission Open
Keywords: cardiovascular disease; vascular smooth muscle cell (VSMC); phenotypic modulation; VSMC migration; atherosclerosis; VSMC plasticity; vascular injury; foam cells; stroke; myocardial infarction; peripheral artery disease (PAD); restenosis; inflammation; metabolism
(This special issue belongs to the Section Cells of the Cardiovascular System)
Innate Immunity in Health and Disease submission deadline 31 Dec 2024 | 8 articles | Viewed by 19650 | Submission Open
Keywords: innate immunity; homeostasis; disease; inflammation; PAMPs; DAMPs; pattern recognition receptors; phagocytes; innate lymphoid cells; neutrophils
(This special issue belongs to the Section Cellular Immunology)
Understanding Aging Mechanisms to Prevent Age-Related Diseases
edited by Pierre Jouanny, Sonia Hammami, and
submission deadline 31 Dec 2024 | 7 articles | Viewed by 18377 | Submission Open
(This special issue belongs to the Section Cellular Aging)
Potential of CAR-Based Cellular Immunotherapy for Non-oncologic Disorders submission deadline 31 Dec 2024 | 3 articles | Viewed by 13443 | Submission Open
Keywords: adoptive cell transfer; CAR-T cells; cell engineering; CAR products; CAR-T cell therapy; non-oncologic disorders; autoimmune diseases; cardiometabolic diseases; inflammatory organ fibrosis; senescent cell pathologies; infections
(This special issue belongs to the Section Cellular Immunology)
Model Systems for Human Disease and Medicine: From Advanced Cell and Tissue Culture to In Silico Methods
edited by
submission deadline 31 Dec 2024 | 5 articles | Viewed by 13272 | Submission Open
Keywords: modelling; human model systems; in vitro; cells; stem cells; pluripotent stem cells; iPSC; tissue; organoid; organ-on-a-chip; cell-on-a-chip; in silico; disease; cancer; regenerative medicine; diagnostics; therapeutics
(This special issue belongs to the Section Cell Methods)
Emerging Roles of Glial Cells in Human Health and Disease submission deadline 31 Dec 2024 | 5 articles | Viewed by 12344 | Submission Open
Keywords: neurodegenerative diseases; glia cells; astrocyte; microglia; stroke; pain; epilepsy; trauma; demyelinating diseases’ inflammatory diseases; satellite glia; Schwann cells; enteric glia
(This special issue belongs to the Section Cells of the Nervous System)
Cellular and Molecular Basis of Wound Healing II submission deadline 31 Dec 2024 | 3 articles | Viewed by 10871 | Submission Open
Keywords: scratch wound assay; Ca2+ signaling; burns and wound healing; keratinocytes biology; matrix remodelling; inflammation and wound healing; gene therapy in wound healing; wound management; wound healing; tissue regeneration; cell and molecular biology; wounds; difficult-to-heal wounds; chronic/acute wounds
(This special issue belongs to the Section Cellular Pathology)
The Cell Biology of Fertilization submission deadline 31 Dec 2024 | 6 articles | Viewed by 7693 | Submission Open
Keywords: oocyte maturation; acrosome reaction; gamete interaction; actin remodelling; calcium; monospermy
(This special issue belongs to the Section Cell Proliferation and Division)
Cell Biology: State-of-the-Art and Perspectives in Italy 2024
edited by
submission deadline 31 Dec 2024 | 6 articles | Viewed by 7156 | Submission Open
Molecular and Cellular Mechanisms of Lymphomas submission deadline 31 Dec 2024 | 5 articles | Viewed by 7028 | Submission Open
Keywords: lymphoma; pathogenes and lymphomas; molecular pathogenesis; molecular diagnosis; cellular or gene-targeted therapy; cell metabolism
(This special issue belongs to the Section Cellular Pathology)
Recent Research on the Role of Mitochondria in Neurodegeneration
edited by
submission deadline 31 Dec 2024 | 3 articles | Viewed by 6491 | Submission Open
Keywords: mitochondrial; neurodegeneration; metabolism; mitophagy; apoptosis
(This special issue belongs to the Section Cells of the Nervous System)
Select Topics in Molecular and Cellular Mechanisms of Mammalian Reproduction
edited by Zhengui Zheng, and Liang Ma
submission deadline 31 Dec 2024 | 3 articles | Viewed by 5823 | Submission Open
Keywords: reproductive organ development; sexual differentiation; reproductive tract function; fertilization; implantation; placentation; parturition; lactation
(This special issue belongs to the Section Reproductive Cells and Development)
Mitochondrial Biology and Pathophysiology
edited by and Laura Formentini
submission deadline 31 Dec 2024 | 1 articles | Viewed by 5170 | Submission Open
Keywords: mitochondria; age-related diseases; animal models; cell death; immune responses; metabolic responses; mitochondrial structure; dynamics and function proteostasis
(This special issue belongs to the Section Cellular Pathology)
Gastrointestinal Disease: From Cellular Mechanisms to Targeted Therapy submission deadline 31 Dec 2024 | 3 articles | Viewed by 5116 | Submission Open
Keywords: gastrointestinal cancer; gastric cancer; colorectal cancer; esophageal cancer; liver cancer; pancreatic cancer; inflammatory bowel disease; miRNAs; in vitro and in vivo models; molecular networks; molecular pathways; translational medicine; epithelial barrier functions/processes
(This special issue belongs to the Section Cellular Pathology)
Advances in Zebrafish Cardiac Disease Models
edited by
submission deadline 31 Dec 2024 | 2 articles | Viewed by 5052 | Submission Open
Keywords: zebrafish; heart; cardiomyocytes; heart disease; cardiac hypertrophy; regenerative medicine; cardiac regeneration; translational models
(This special issue belongs to the Section Cells of the Cardiovascular System)
Exclusive Review Papers in Autophagy—Second Edition
edited by
submission deadline 31 Dec 2024 | 2 articles | Viewed by 4787 | Submission Open
Keywords: biquitination; autophagy; peroxisomes; macroautophagy; pexophagy; mitophagy; lysosome; vacuole; organellar homeostasis; posttranslational modifications; lipids; signaling cascades
(This special issue belongs to the Section Autophagy)
Redox and Metabolic Profile of Cancer
edited by
submission deadline 31 Dec 2024 | 2 articles | Viewed by 4511 | Submission Open
Keywords: cancer; metabolism; redox biology; redox-metabolic reprogramming; reactive species: oxygen; nitrogen; sulfur; etc; cancer microenvironment; cancer-tissue cooperation; mitochondria
(This special issue belongs to the Section Cellular Metabolism)
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