Sex Differences in Cardiovascular Structure and Function—from Mechanisms to Therapeutics
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 31 May 2026 | Viewed by 1789
Special Issue Editors
Interests: vascular biology; sex differences; metabolic disease
2. College of Medicine Phoenix, University of Arizona, Phoenix, AZ 85004, USA
Interests: vascular biology; aneurysms; endothelial function; angiotensin signaling; genetic aortic diseases
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Sex as a biological variable shapes cardiovascular development, disease risk, clinical presentation, and therapeutic response—yet many pathways and practice patterns remain incompletely understood or underexamined. This Special Issue of Cells invites work that bridges basic discovery with translational and clinical impact, advancing truly sex‐informed cardiovascular research and care.
This Special Issue invites studies that connect cellular and molecular mechanisms (e.g., genomic/epigenomic regulation, mitochondrial and metabolic biology, immune–inflammatory drivers, vascular remodeling, extracellular matrix, and electrophysiology) and hormonal influences (estrogens, androgens, menopause, pregnancy/postpartum) to phenotypes and outcomes across heart and vascular disease. Submissions translating biology into prevention, diagnostics, pharmacologic, and therapeutics are especially encouraged.
Dr. Roshanak Rahimian
Dr. Mitra Esfandiarei
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cardiovascular diseases
- sex hormones
- sex differences
- vascular and cell signaling
- therapeutic targets
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