Basic Mechanisms and Emerging Therapeutic Strategies for Spinal Cord Injury
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 25 May 2026 | Viewed by 2
Special Issue Editors
Interests: spinal cord injury; nerve injuries; drug delivery; lipid nanoparticles
Special Issue Information
Dear Colleagues,
Spinal cord injury (SCI) results in sensory, motor, and autonomic impairments, along with other associated medical conditions that severely decrease the patient's quality of life. Despite the considerable economic and societal challenges, no clinical therapy is available for substantial recovery of functional deficits after SCI. However, over the past few decades, impactful progress has been made in basic science research and translational studies aimed at treating SCI.
This Special Issue highlights the significant advances made in reducing secondary damage after SCI and progress toward regeneration after SCI. Notable progress has been achieved in understanding the signaling cues and cellular infiltration involved in post-injury inflammation. Additionally, there have been substantial improvements in promoting neural repair through the use of stem cells, neurotrophic factors, degradation of inhibitory extracellular matrix components, and innovations in drug delivery methods.
We therefore invite researchers to submit high-quality original research articles, communications, and review articles across all fields related to SCI, with a focus on basic cellular and molecular mechanisms.
Dr. Daniel J. Hellenbrand
Dr. Angela R. Filous
Guest Editors
Manuscript Submission Information
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Keywords
- spinal cord injury
- neuroinflammation
- neural regeneration
- axon growth
- neurons
- glial cells
- oligodendrocytes
- myelin
- astrocytes
- microglia
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