Cell Therapy for Retinal Diseases

A special issue of Cells (ISSN 2073-4409).

Deadline for manuscript submissions: 20 October 2025 | Viewed by 242

Special Issue Editors


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Guest Editor
Instituto Universitario de Oftalmobiología Aplicada (IOBA), Universidad de Valladolid, Valladolid, Spain
Interests: retinal diseases; cell therapy; regenerative medicine; stem cells; cell secretome; neuroprotection
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Guest Editor
Department of Tissue Engineering & Regenerative Medicine (DTERM), Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
Interests: cellular therapy; tissue engineering

Special Issue Information

Dear Colleagues,

Retinal diseases, including age-related macular degeneration, diabetic retinopathy, and inherited retinal dystrophies, are leading causes of vision loss worldwide. Despite advances in ophthalmology, effective treatments remain a significant challenge, with current therapies often only slowing disease progression without restoring lost vision.

Cell therapy has emerged as a promising strategy to repair or replace damaged retinal cells, offering new hope for patients with currently untreatable conditions. Advances in stem cell biology, gene editing, tissue engineering, and neuroprotection have accelerated the development of cell-based therapies for retinal diseases, including the use of pluripotent stem cells, cell transplantation, and cell reprogramming techniques.

This Special Issue will highlight recent breakthroughs in cell therapy for retinal diseases, addressing key challenges such as immune rejection, cell integration, and functional restoration. Contributions exploring novel in vitro and in vivo models, neuroprotection, reprogramming approaches, cell sources, delivery methods, clinical translation, and long-term efficacy are especially welcome. We aim to provide a comprehensive overview of the current state and future prospects of cell-based approaches in retinal medicine.

We look forward to your valuable contributions

Dr. Girish Kumar Srivastava
Dr. Yogeswaran Lokanathan
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • retinal diseases
  • cell therapy
  • stem cells
  • retinal regeneration
  • cell transplantation
  • gene editing in retinal therapy
  • tissue engineering
  • retinal organoids
  • vision restoration
  • clinical translation of cell therapy
  • future directions in retinal regeneration

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Published Papers

This special issue is now open for submission.
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