Endometrial Cancer: From Molecular Mechanisms to Therapeutic Approaches
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 31 May 2026 | Viewed by 205
Special Issue Editors
Interests: breast & gynecologic cancers; somatic mutations; epigenetics; gene regulatory networks; sex hormones; liquid biopsy; drug delivery; cancer treatment
Interests: endometrial cancer; endometriosis; biomarkers in gynecology; ultrasound; gynecological oncology
Special Issue Information
Dear Colleagues,
The prevalence of endometrial cancer (EC) has been rising steadily for more than two decades, with EC proving fatal to an increasing number of women. Problems in early diagnostics are often a result of false-negative rates, uncomfortable procedures, and low-resolution imaging techniques. Furthermore, the existing treatment options frequently encounter limitations relating to drug resistance, adverse effects, and a lack of specificity. Therefore, there is a necessity to broaden our understanding of this malignancy to enhance patient outcomes.
This Special issue aims to elucidate the molecular and cellular characteristics of EC neoplasms in relation to the development of novel therapeutic approaches or the improvement of existing ones. Submissions may address, but are not limited to, the following areas:
- Molecular (e.g. genetic and epigenetic mechanisms, cell metabolism, cell signalling, and redox homeostasis) and cellular (e.g. CSCs, EMT, and TIME) mechanisms leading to tumorigenesis, tumour growth, and its dissemination;
- Tumour glycobiology;
- Risk factors (e.g. hormonal fluctuations, HPV, and microbiota);
- Molecular biomarkers for disease monitoring;
- Advances and challenges associated with current disease management and treatment;
- Novel therapeutic approaches.
Studies utilising humans, animal models, and in silico approaches in combination with in vitro studies are welcomed.
Dr. Tomaž Büdefeld
Dr. Jure Knez
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- endometrial cancer
- genetic mutation
- epigenetics
- cell signaling
- TIME
- metastasis
- biomarker
- therapy
- drug delivery
- risk factor
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