G Protein-Coupled Receptors and Diseases
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 31 May 2026 | Viewed by 1483
Special Issue Editor
Interests: cancer; autophagy; cell death; cell proliferation; cell signaling; reactive oxygen species; mitochondria; apoptosis; ferroptosis; necroptosis; oral biology; microbiota; clinical trial; pulmonary hypertension; G protein-coupled receptor
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Special Issue Information
Dear Colleagues,
G protein-coupled receptors (GPCRs) are the largest family of cell membrane receptor proteins in eukaryotic cells. These proteins sense stimuli from the environment and transmit the signals from outside the cell to the inside. GPCRs play diverse roles in cellular physiology and functions, such as cell survival, cell proliferation, the interactions between humans and the microbiome, and taste sensing. They are associated with many diseases, such as diabetes, cancer, oral diseases, lung diseases, aging, cardiovascular diseases, and neurodegeneration. Thus, they are attracting significant attention in the drug development field.
Extensive ongoing studies are exploring GPCRs’ roles in the mechanisms and treatment of diseases.
This Special Issue will showcase original research and review articles on GPCR-associated disease studies. Examples of possible research topics include, but are not limited to, the following:
- Mechanistic studies on GPCR-mediated signaling pathways that regulate disease etiology and treatment in cellular and animal models;
- Cell or molecular biology studies on GPCR-targeting drugs;
- Associations of taste receptors with diseases;
- Bioinformatic analyses of GPCR-regulated disease development and treatment (including cytological experiments).
Dr. Yongqiang Chen
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- G protein-coupled receptor
- taste receptor
- microbiome
- cancer
- aging
- neurodegenerative disease
- cardiovascular disease
- pulmonary hypertension
- cell survival
- cell death
- apoptosis
- autophagy
- necroptosis
- ferroptosis
- proliferation
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