Special Issues

Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

Section
Search by Title/Keyword
 
Order results
Display
Results per page
Stem Cells in Cancer
edited by
submission deadline 10 Nov 2025 | 2 articles | Viewed by 7062 | Submission Open
Keywords: cancer stem cells; heterogeneity; metastasis; plasticity; self-renewal
(This special issue belongs to the Section Stem Cells)
Molecular Mechanism and Therapeutic Opportunities of Breast Cancer submission deadline 10 Nov 2025 | 3 articles | Viewed by 3856 | Submission Open
Keywords: breast cancer; molecular mechanisms; targeted therapy; genomic profiling; hormone receptors; tumor microenvironment; immunotherapy; drug resistance; metastasis; precision medicine
(This special issue belongs to the Section Cellular Pathology)
Synaptic Plasticity and the Neurobiology of Learning and Memory
edited by Erica Berretta, Laura Petrosini and Anna Panuccio
submission deadline 10 Nov 2025 | 1 articles | Viewed by 2028 | Submission Open
Keywords: learning and memory; neuronal and glial cells; long-term potentiation and long-term depression; molecular mechanisms
(This special issue belongs to the Section Cells of the Nervous System)
Recent Advances in the Molecular Mechanisms of Neurodegenerative Diseases: Current Progress and Future Directions for Disease-Modifying Therapies submission deadline 10 Nov 2025 | 1 articles | Viewed by 1240 | Submission Open
Keywords: neuroprotection; new drug development; natural products; blood– brain barrier; molecular mechanisms; neuronal signaling; neuroinflammation; microglial cells; neurotoxicity; neurodegenerative diseases
(This special issue belongs to the Section Cellular Aging)
Biomarkers in Breast Cancer
edited by Julie Decock and Sana A. Bentebbal
submission deadline 10 Nov 2025 | 1 articles | Viewed by 1216 | Submission Open
Keywords: breast cancer biomarkers; AI in oncology; multi-omics; exosomes; tumor immune microenvironment; liquid biopsy; precision oncology; personalized medicine
(This special issue belongs to the Section Cellular Pathology)
Immunoregulation in Cardiovascular Disease
edited by
submission deadline 10 Nov 2025 | 1 articles | Viewed by 787 | Submission Open
Keywords: cardiovascular disease (CVD); immunoregulation; inflammation; immune cells; immune mediators; immunomodulatory therapies; biomarkers; epigenetics; microbiome; cellular methods/technologies
Modeling Developmental Processes and Disorders in Zebrafish submission deadline 15 Nov 2025 | 13 articles | Viewed by 51263 | Submission Open
(This special issue belongs to the Section Cellular Biophysics)
Effects and Mechanisms of Environmental Toxicants and Nanoparticles on Germ Cells, Gonads, Embryos and Stem Cells
edited by , , and Giulia Fiorentino
submission deadline 15 Nov 2025 | 1 articles | Viewed by 3251 | Submission Open
Keywords: environmental toxicants; gonadal steroid hormones; ovary; folliculogenesis; oogenesis and oocyte; testis; spermatogenesis and sperm; embryo development; epigenetics; omics; cells lines and stem cells; embryoid bodies; gastruloids and organoids; 3D cell culture and imaging; nanoparticles; nanomaterials
(This special issue belongs to the Section Stem Cells)
Advances in Intestinal Epithelial Plasticity and Regeneration
edited by
submission deadline 15 Nov 2025 | 1 articles | Viewed by 3196 | Submission Open
Keywords: intestinal epithelium; epithelial plasticity; stem cells; tissue repair; self-renewal; regeneration
Innate-Like T Cells: The Variegated Roles of Semi-Invariant TCRs in Health and Disease
edited by and Akshat Sharma
submission deadline 15 Nov 2025 | Viewed by 2134 | Submission Open
Keywords: innate-like T cells; cancer; autoimmunity; cytokines; immune mechanisms
(This special issue belongs to the Section Cellular Pathology)
Novel Therapies and Biomarkers for Rare Diseases
edited by Reena Kartha
submission deadline 15 Nov 2025 | Viewed by 225 | Submission Open
Keywords: rare diseases; translational research; novel therapies; biomarker discovery; precision medicine
The Role of Integrins and Small GTPases in Health and Disease
edited by
submission deadline 15 Nov 2025 | Viewed by 138 | Submission Open
Keywords: cell signaling; integrins; cell adhesion; integrins diseases; infectious diseases
Lipids and Lipidomics in Neurodegenerative Diseases
edited by and Catherine Malaplate
submission deadline 20 Nov 2025 | 1 articles | Viewed by 12250 | Submission Open
Keywords: lipids; lipidomics; neurodegenerative disease diagnosis; prevention; or treatment; cellular and molecular mechanisms
(This special issue belongs to the Section Cells of the Nervous System)
Molecular Advances in Prenatal Exposure to Environmental Toxicants submission deadline 20 Nov 2025 | 4 articles | Viewed by 10920 | Submission Open
Keywords: prenatal exposures; toxicogenomics; epigenomics; placenta; perinatal outcomes; neurodevelopmental outcomes; respiratory outcomes
Second Edition of Advances in Adipose Tissue Biology
edited by
submission deadline 20 Nov 2025 | 2 articles | Viewed by 3905 | Submission Open
Keywords: adipocyte differentiation; progenitors; and stem cells; adipokines; myokines; hepatokines; cytokines; cellular signaling; and molecular crosstalk; white adipose tissue (WAT) and brown adipose tissue (BAT); beige fat and browning of WAT; research techniques and methodologies; diagnostics and therapeutics; genomics; metabolomics; other ‘ omics’ technologies; metabolic syndrome; obesity; insulin resistance; cancer
(This special issue belongs to the Section Tissues and Organs)
Molecular Mechanism of Liver Transplantation
edited by Carmen Peralta and Juan Carlos Cutrin
submission deadline 20 Nov 2025 | 1 articles | Viewed by 3902 | Submission Open
Keywords: liver transplantation; ischemia-reperfusion injury; signaling pathways; graft dysfunction; sterile inflammation; liver regeneration; fatty grafts; normothermic machine perfusion; defatting strategies
(This special issue belongs to the Section Tissues and Organs)
Tumor Stroma Interaction
edited by
submission deadline 20 Nov 2025 | 1 articles | Viewed by 1815 | Submission Open
Keywords: cells; cancer; inflammation; exocytosis; immune system; tumor stroma
Decoding the Complexity of Angiogenesis: Insights into Vascular Formation and Disease submission deadline 20 Nov 2025 | 2 articles | Viewed by 1563 | Submission Open
Keywords: angiogenesis; vasculogenesis; development; physiological angiogenesis; pathophysiology; cell– cell communication; cell signaling
(This special issue belongs to the Section Cells of the Cardiovascular System)
Recent Advances in the Study of Tau Protein
edited by
submission deadline 20 Nov 2025 | 1 articles | Viewed by 1435 | Submission Open
Keywords: tau protein; post-translational modification; tauopathy filaments; neuro-immune interactions
(This special issue belongs to the Section Cells of the Nervous System)
Ripening and Degradation Mechanisms of Neutrophil Extracellular Traps
edited by and Maximilian Dölling
submission deadline 20 Nov 2025 | Viewed by 481 | Submission Open
Keywords: neutrophil extracellular traps; degradation of NETs; ripening of NETs
(This special issue belongs to the Section Cellular Immunology)
Aging and Metabolic Diseases
edited by
submission deadline 20 Nov 2025 | Viewed by 465 | Submission Open
Keywords: aging; insulin resistance; diabetes; obesity; mitochondrial dysfunction; beta-galactosidase; senescent-associated secretory phenotype; pancreatic beta cells
(This special issue belongs to the Section Cellular Aging)
Extracellular Vesicles Based Drug Delivery submission deadline 20 Nov 2025 | Viewed by 358 | Submission Open
Keywords: EV engineering; targeting; therapy; natural carrier; exosomes
Genetic and Genomic Insights into Complex Human Diseases: Advances, Challenges and Integrative Approaches
edited by Tianxiao Huan and Chan Zhou
submission deadline 20 Nov 2025 | Viewed by 195 | Submission Open
Keywords: genetics; genomics; proteomics; complex diseases; multi-omics; machine learning
Epigenetic Regulation in Plant–Microbe Interactions and Environmental Adaptation
edited by Zhongshou Wu and Bochen Jiang
submission deadline 20 Nov 2025 | Viewed by 195 | Submission Open
Keywords: epigenetic regulation; plant– microbe interactions; environmental adaptation
(This special issue belongs to the Section Plant, Algae and Fungi Cell Biology)
Transient Receptor Potential (TRP) Channels and Health and Disease
edited by Hiroki Kittaka and Makoto Tominaga
submission deadline 20 Nov 2025 | Viewed by 154 | Submission Open
Keywords: Transient Receptor Potential (TRP) channels; cell signaling; cell physiology
Acute Liver Failure: Molecular Actors in Liver–Adipose Tissue Interplay
edited by Marika Crescenzi
submission deadline 20 Nov 2025 | Viewed by 152 | Submission Open
Keywords: inflammasome; adipose tissue; acute liver injury; adipokines; liver macrophages; hepatic stellate cells; liver sinusoidal endothelial cells
(This special issue belongs to the Section Tissues and Organs)
Methane Biosynthesis
edited by , James Ferry and
submission deadline 20 Nov 2025 | Viewed by 150 | Submission Open
Keywords: methane; methanogenesis; methanogens; carbon cycle; gut microbiota; energy conservation; human diseases
The Metabolic Interactions and Pathways in Cancers
edited by Mohamed Elgendy
submission deadline 20 Nov 2025 | Viewed by 126 | Submission Open
Keywords: cancer metabolism; metastasis; drug resistance; oncometabolites; metabolic plasticity; diet; bioenergetics; metabolic crosstalk; immunotherapy
New Insights into Astrocytes in Health and Disease
edited by
submission deadline 20 Nov 2025 | Viewed by 100 | Submission Open
Keywords: astrocytes heterogeneity; blood-brain barrier (BBB); synaptic modulation; metabolic support; neuroinflammation; ageing; neurodegenerative disorders; neurodevelopmental disorders; stress response
(This special issue belongs to the Section Cells of the Nervous System)
Targeting Tumor Metabolism and Epigenetics: Mechanisms and Therapeutic Strategies
edited by , and Íñigo Casafont
submission deadline 22 Nov 2025 | Viewed by 250 | Submission Open
Keywords: tumor metabolism; epigenetics; metabolic reprogramming; DNA methylation; histone modification; warburg effect; glycolysis inhibitors; fatty acid synthesis; chromatin remodeling; cancer therapy
(This special issue belongs to the Section Cellular Metabolism)
Cellular and Molecular Basis in Chronic Kidney Disease submission deadline 25 Nov 2025 | 8 articles | Viewed by 20166 | Submission Open
Keywords: CKD; renal inflammation; renal fibrosis; RAAS; aldosterone; TGF-B1; uremic toxins; hypertension; GFR; albuminuria
(This special issue belongs to the Section Cellular Pathology)
Glial Cells in Aging Neuroscience
edited by
submission deadline 25 Nov 2025 | 2 articles | Viewed by 7313 | Submission Open
Keywords: glial cells; aging; neuroinflammation; neurodegeneration; glial– neuronal interactions; glial– glial crosstalk; astrocytes; oligodendrocytes; microglia; ependymal cells
(This special issue belongs to the Section Cellular Aging)
Biomolecular Condensates in Oncology and Immunology submission deadline 25 Nov 2025 | 1 articles | Viewed by 1332 | Submission Open
Keywords: liquid-liquid phase separation (LLPS); biomolecular condensates; pro-oncogenic signaling; innate and adaptive immunity; transcriptional regulation; epigenetic regulation; condensate targeting; antiviral mechanisms; intercellular adhesion; cell migration and metastasis
(This special issue belongs to the Section Cellular Immunology)
CAR T Cells in Human Cancers submission deadline 25 Nov 2025 | 1 articles | Viewed by 1092 | Submission Open
Keywords: CAR T cells; engineered immune cell therapies; CAR T cell engineering
Cell Signaling in Neurodegeneration Disease
edited by , Yasuhiro Funahashi, , and Md-nadim Hossain
submission deadline 25 Nov 2025 | Viewed by 253 | Submission Open
Keywords: neurodegeneration; cell signaling; biomarkers; synaptic dysfunction; neuroinflammation; protein aggregation; IPSC and animal models; mitochondrial dysfunction; therapeutic targets; translational neuroscience
(This special issue belongs to the Section Cells of the Nervous System)
Pathology and Treatments of Amyotrophic Lateral Sclerosis (ALS)
edited by Laxman Gangwani
submission deadline 28 Nov 2025 | 1 articles | Viewed by 2201 | Submission Open
Keywords: amyotrophic lateral sclerosis (ALS); pathology; molecular mechanisms; treatments; symptom management; biological mechanisms; risk factors; innovative treatments
(This special issue belongs to the Section Cellular Pathology)
Cellular Senescence and Senotherapies in the Aging Retina
edited by
submission deadline 28 Nov 2025 | Viewed by 327 | Submission Open
Keywords: retina; senescence; aging; inflammasome; oxidative stress; antioxidant; gene therapy; senotherapies; glaucoma; diabetic retinopathy
(This special issue belongs to the Section Cellular Aging)
Cell-to-Cell Crosstalk as a Target of Therapies submission deadline 30 Nov 2025 | 2 articles | Viewed by 11077 | Submission Open
Keywords: cell-to-cell crosstalk; cellular communication; microenvironment; extracellular vesicles; diagnostic tools; membrane nanotubes; pathogenesis; therapy; cell metabolism; homeostasis
(This special issue belongs to the Section Cell Microenvironment)
Gastrointestinal Cancer: From Cellular and Molecular Mechanisms to Therapeutic Opportunities submission deadline 30 Nov 2025 | 4 articles | Viewed by 8129 | Submission Open
Keywords: colorectal cancer; gastric cancer; liver cancer; pancreatic cancer; tumor microenvironment; cytokines; epigenetic; checkpoint inhibitors; biomarkers; immunotherapy
(This special issue belongs to the Section Cellular Pathology)
Emerging Insights into Natural Killer Cell Immunity in Infection and Cancer
edited by Sumit Sen Santara, , Weshely Kujur and Sachin Mulik
submission deadline 30 Nov 2025 | 4 articles | Viewed by 7920 | Submission Open
Keywords: CAR NK cells; cancer immunotherapy; cell therapy; viral infection; memory NK cells; NK cell targeted therapies; NK-immune cell crosstalk; exosomes
(This special issue belongs to the Section Cellular Immunology)
New Research on Immunity and Inflammation in Cardiovascular Disease
edited by Pavel Poredoš
submission deadline 30 Nov 2025 | 7 articles | Viewed by 7536 | Submission Open
Keywords: inflammation; atherosclerosis; coronary artery disease; peripheral arterial disease; cerebrovascular disease; venous thromboembolic disease; circulating biomarkers; anti-innflammatory treatment of cardiovascular disease
(This special issue belongs to the Section Cells of the Cardiovascular System)
Recent Advances in Metabolism and Oxidative Stress in Human Diseases: 2nd Edition
edited by and Vanessa Cossu
submission deadline 30 Nov 2025 | 4 articles | Viewed by 7119 | Submission Open
Keywords: antioxidant responses; redox balance; ROS; hematologic oncology; solid tumors; immune response; ATP; cancer cells; mitochondria-ER interactions; endoplasmic reticulum; glucose metabolism; inflammation; mitochondria; mitochondrial dynamics; autophagy; mitophagy; metabolic plasticity; metabolism
(This special issue belongs to the Section Cellular Metabolism)
Advances in Muscle Research in Health and Disease—2nd Edition
edited by
submission deadline 30 Nov 2025 | 3 articles | Viewed by 5800 | Submission Open
Keywords: skeletal muscle; cardiac muscle; smooth muscle; myocyte; vascular smooth muscle cell; stem cell; development; homeostasis; regeneration; biomarker; therapeutic target
(This special issue belongs to the Section Tissues and Organs)
Harnessing the Tumor Microenvironment and Signaling Pathways for Precision Cancer Therapy
edited by Behzad M. Toosi and
submission deadline 30 Nov 2025 | 2 articles | Viewed by 4746 | Submission Open
Keywords: tumor microenvironment (TME); signaling pathways; precision cancer therapy; immune evasion; metabolic pathways; tumor– stroma interactions; therapeutic targets; personalized medicine; cancer metastasis; molecular oncology
(This special issue belongs to the Section Cell Microenvironment)
Role of Calpains in Health and Diseases
edited by and Peter A. Greer
submission deadline 30 Nov 2025 | 4 articles | Viewed by 4709 | Submission Open
Keywords: calpain; physiology; biochemistry; disease; mutation; target; inhibitor
(This special issue belongs to the Section Cellular Pathology)
Retinal Pigment Epithelium in Degenerative Retinal Diseases
edited by Jian Liu and Shintaro Horie
submission deadline 30 Nov 2025 | 3 articles | Viewed by 4619 | Submission Open
Keywords: RPE; degenerative retinal diseases; macular degeneration; diabetic retinopathy; glaucoma; photoreceptor; vascular endothelium; microglia; macrophage; inflammation; oxidative stress; autophagy; mitochondria; lipid metabolism; senescence; neuropeptide; therapeutics; biomarkers
(This special issue belongs to the Section Cellular Pathology)
Genetic and Cellular Basis of Autoimmune Diseases
edited by
submission deadline 30 Nov 2025 | 2 articles | Viewed by 3804 | Submission Open
Keywords: autoimmune disease; break of tolerance; effector cells; immunodysregulation; risk genes
(This special issue belongs to the Section Cellular Immunology)
Osteoblasts, Osteoclasts and Bone Diseases: Cellular Crosstalk and Therapeutic Opportunities
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 3678 | Submission Open
Keywords: osteoblasts; osteoclasts; bone remodelling; osteoporosis; skeletal diseases; bone homeostasis; bone interactions; bone crosstalk; targeted therapies
(This special issue belongs to the Section Cellular Pathology)
Cellular Mechanisms in Mitochondrial Function and Calcium Signaling
edited by Sergio De la Fuente and Jaime Santo-Domingo
submission deadline 30 Nov 2025 | 2 articles | Viewed by 3671 | Submission Open
Keywords: mitochondria; calcium; MCU; uniporter; NCLX; energy metabolism; disease; MAMs; signaling
(This special issue belongs to the Section Cellular Metabolism)
Advances in Musculoskeletal Tissue Regeneration Using Mesenchymal Stromal/Stem Cells, Biomaterials, and Signaling Molecules: Second Edition submission deadline 30 Nov 2025 | 2 articles | Viewed by 3405 | Submission Open
Keywords: mesenchymal stromal/stem cells; extracellular vesicles; biomaterials; signalling molecules; microphysiological systems; musculoskeletal regeneration; immunomodulation; cell therapy; tissue engineering
(This special issue belongs to the Section Stem Cells)
Back to TopTop