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Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Skeletal Muscle Atrophy in Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities

edited by

Marco Vincenzo Narici

submission deadline 15 Oct 2024 | 1 articles | Viewed by 1648 | Submission Open

Keywords: muscle atrophy; inactivity; ageing; sarcopenia; neuromuscular disorders

(This special issue belongs to the Section Cellular Pathology)

Biology and Potential Medical Applications of Mesenchymal Stem Cell Exosomes

edited by George G. Koliakos

submission deadline 15 Oct 2024 | 1 articles | Viewed by 1321 | Submission Open

Keywords: mesenchymal stem cells; extracellular vesicles; exosomes; exosomes in drug delivery; intercellular signaling; diagnosis and therapy; exosome miRNA packaging and transfer; exosome isolation; characterization and analysis; molecular signals controlling exosome production and release

(This special issue belongs to the Section Stem Cells)

Biological Pathways and Molecular Mechanisms of Dementia—Second Edition

edited by

Wataru Araki

and

Madepalli K. Lakshmana

submission deadline 15 Oct 2024 | Viewed by 190 | Submission Open

Keywords: Alzheimer’ s disease; frontotemporal dementia; dementia with Lewy bodies; amyloid-β ; tau; TDP-43; FUS; α -synuclein; neurodegeneration; neuropathology; neuroinflammation

(This special issue belongs to the Section Cellular Aging)

Role of Inflammasome Activation in Innate and Adaptive Immunity

edited by

Juan Pablo de Rivero Vaccari

Robert W. Keane

and

W. Dalton Dietrich

submission deadline 20 Oct 2024 | 5 articles | Viewed by 8548 | Submission Open

Keywords: inflammasome; caspase-1; ASC specks; pyroptosis; innate immunity; adaptive immunity; sterile inflammation; cell death pathways; apoptosis; autophagy; NETosis; PANoptosis; ferroptosis; necroptosis; neurodegenerative disease; trauma; cerebral ischemia; biomarkers

(This special issue belongs to the Section Cellular Immunology)

Autophagy and Inflammasome

edited by

Nataša Kopitar Jerala

submission deadline 20 Oct 2024 | 1 articles | Viewed by 1722 | Submission Open

Keywords: autophagy; inflammasome; immune response inflammasome; mitochondrial ROS; myeloid cells; mTOR signaling

(This special issue belongs to the Section Autophagy)

Molecular Mechanisms of Autism Spectrum Disorder

edited by Tanya Gandhi and

Charles Lee

submission deadline 20 Oct 2024 | 1 articles | Viewed by 1256 | Submission Open

Keywords: autism spectrum disorder; neurodevelopmental disorders; molecular mechanisms; cellular-molecular mechanisms; neurobiological mechanisms; neural mechanisms; intervention approaches; treatment strategies

(This special issue belongs to the Section Cells of the Nervous System)

Inflammation: The Major Player in Metabolic Syndrome

edited by

Zhenwei Gong

submission deadline 20 Oct 2024 | Viewed by 257 | Submission Open

Keywords: inflammasomes; energy metaboism; metabolic syndrome; chronic inflammation; cytokine production

Mitophagy, Autophagy, Apoptosis and Senescence—the Roles of These Processes in Invasive Cancer Growth: Second Edition

edited by Julia Federspiel and

Jozsef Dudas

submission deadline 20 Oct 2024 | Viewed by 216 | Submission Open

Keywords: apoptosis; autophagy; mitophagy; senescence; cancer cell death mechanisms

(This special issue belongs to the Section Autophagy)

Advance in Ca²⁺ Homeostasis

edited by

Sylvie Ducreux

submission deadline 20 Oct 2024 | Viewed by 213 | Submission Open

Keywords: calcium homeostasis; skeletal muscle; cardiac muscle; excitation– contraction coupling; calcium channel; calcium pumps and exchangers; mitochondria and calcium; sarcoplasmic reticulum and calcium; calcium binding protein; calcium signaling; muscular disease; cardiovascular disease

Molecular Damage and Repair Mechanisms in COPD

edited by

Simon D. Pouwels

submission deadline 20 Oct 2024 | Viewed by 183 | Submission Open

Keywords: COPD; DAMPs; danger signals; cell death; pattern recognition receptors; RAGE; HMGB1; necroptosis; biomarkers; toll-like receptors

(This special issue belongs to the Section Tissues and Organs)

Molecular and Cellular Mechanisms of Treating Fibrosis

edited by Richard Stratton

submission deadline 20 Oct 2024 | Viewed by 131 | Submission Open

Keywords: fibrosis; systemic sclerosis; targeted therapy; extracellular matrix; collagen; organ fibrosis; interstitial lung disease

(This special issue belongs to the Section Cellular Pathology)

Molecular Mechanisms of Signal Transduction in the Islet Cells

edited by

Md Shahidul Islam

submission deadline 20 Oct 2024 | Viewed by 129 | Submission Open

Keywords: islet cells; islets of Langerhans; insulin secretion; signaling mechanisms; molecular mechanisms

(This special issue belongs to the Section Tissues and Organs)

Novel Approaches for Combating Multi-drug Resistant Bacterial Cells

edited by

Razieh Kebriaei

and

Andrew David Berti

submission deadline 20 Oct 2024 | Viewed by 120 | Submission Open

Keywords: antibiotic resistance; novel strategies; novel antibiotics; combination therapies; bacteriophage; host-directed therapies

Cellular and Molecular Mechanisms of Lysosomal Storage Disorders

edited by

Ritva Tikkanen

submission deadline 25 Oct 2024 | 2 articles | Viewed by 4092 | Submission Open

Keywords: lysosomes; lysosomal storage disorders; enzyme replacement; gene therapy; substrate reduction; pharmacological chaperones; autophagy; endosomal dysfunction

(This special issue belongs to the Section Cellular Pathology)

Cancer-Associated Fibroblasts: Challenges and Directions

edited by

Paul J. Higgins

and

Ramesh Mukkamala

submission deadline 25 Oct 2024 | 2 articles | Viewed by 2525 | Submission Open

Keywords: cancer-associated fibroblast (CAFs); tumor microenvironment (TME); fibroblast activation protein alpha (FAPα ); immunotherapy; cytokines; angiogenesis; metastasis; FAP inhibitors; radioligands; imaging agents

(This special issue belongs to the Section Cell Microenvironment)

Perinatal Brain Injury—from Pathophysiology to Therapy

edited by Cora H.A. Nijboer,

Bobbi Fleiss

and

Ivo Bendix

submission deadline 25 Oct 2024 | 1 articles | Viewed by 1905 | Submission Open

Keywords: preterm birth; perinatal brain injury; infection; inflammation; hypoxia; ischemia; hyperoxia; malnutrition; regenerative therapies; pharmacological intervention; stem cells

(This special issue belongs to the Section Cells of the Nervous System)

Novel Insight into Endothelial Function and Atherosclerosis

edited by Antonio Cutruzzolà, Alessandro Salatino and

Concetta Irace

submission deadline 25 Oct 2024 | Viewed by 312 | Submission Open

Keywords: atherosclerosis ; endothelial function ; nitric oxide ; flow-mediated dilation ; biomarkers ; imaging ; arterial wall ; endothelium ; inflammation

(This special issue belongs to the Section Cells of the Cardiovascular System)

Muscle Structure and Function in Health and Disease

edited by

Weikang Ma

submission deadline 30 Oct 2024 | 1 articles | Viewed by 987 | Submission Open

Keywords: muscle regulation; structure; contractility; myosin; actin; titin; myopathies; cardiomyopathies

(This special issue belongs to the Section Cellular Biophysics)

Oxidative Stress and Antioxidant Strategies: Relationships and Cellular Pathways for Human Health

edited by

Alessia Remigante

and

Rossana Morabito

submission deadline 31 Oct 2024 | 9 articles | Viewed by 22766 | Submission Open

Keywords: oxidative stress; antioxidants; aging; human health and diseases

(This special issue belongs to the Section Cellular Pathology)

Idiopathic Pulmonary Fibrosis: Pathogenic Pathways and Treatment Strategies

edited by

Christoffel Arnold Spek

and

Jan Willem Duitman

submission deadline 31 Oct 2024 | 8 articles | Viewed by 19657 | Submission Open

Keywords: idiopathic pulmonary fibrosis; interstitial lung disease; nintedanib; pirfenidone; extracellular matrix; alveolar epithelial injury; bleomycin

(This special issue belongs to the Section Tissues and Organs)

Apoptosis and Alternative Modes of Cell Death as Targets for Anticancer Therapy

edited by

Mustapha Kandouz

submission deadline 31 Oct 2024 | 6 articles | Viewed by 11082 | Submission Open

Keywords: apoptosis; cancer therapy; cell death; autophagy; necroptosis; ferroptosis; pyroptosis; stem cells; small RNAs; extracellular vesicles; intercellular communication

(This special issue belongs to the Section Cellular Pathology)

Stem Cell, Differentiation, Regeneration and Diseases

edited by

Guoying Yu

, Guoqiang Sun and

Jiancheng Liu

submission deadline 31 Oct 2024 | 8 articles | Viewed by 10316 | Submission Open

Keywords: stem cell; development; differentiation; tissue regeneration; organoid; disease modeling; stem cell therapy; cancer

(This special issue belongs to the Section Stem Cells)

Insight into Cardiomyopathy

edited by Sobuj Mia

submission deadline 31 Oct 2024 | 1 articles | Viewed by 10143 | Submission Open

Keywords: heart failure; ventricular dysfunction; hypertrophic cardiomyopathy; dilated cardiomyopathy; cardiac fibrosis; cardiac hypertrophy; biomarkers

(This special issue belongs to the Section Cells of the Cardiovascular System)

Advances in Diabetes Pathophysiology and Treatment

edited by

Carla Perego

and

Paolo Magni

submission deadline 31 Oct 2024 | 3 articles | Viewed by 9728 | Submission Open

Keywords: diabetes mellitus; insulin resistance; islet of Langerhans; insulin; incretin; glucose homeostasis; (ectopic) adipose tissue; adipokines; liver; diabetes cardiovascular complications

(This special issue belongs to the Section Cellular Pathology)

Cellular Mechanisms Associated with Intermittent Hypoxia

edited by

Asuncion Rocher

and

Philip I. Aaronson

submission deadline 31 Oct 2024 | 3 articles | Viewed by 8029 | Submission Open

Keywords: intermittent hypoxia; reactive oxygen species; oxidative stress; hypoxia inducible factors; inflammation; DNA methylation; cell signalling; transcriptional responses; autonomic dysfunction; insulin resistance; endothelial dysfunction; systemic and pulmonary hypertension

(This special issue belongs to the Section Cellular Pathology)

The Role of Cellular Senescence in Health, Disease, and Aging

edited by

Yasumichi Inoue

submission deadline 31 Oct 2024 | 4 articles | Viewed by 6892 | Submission Open

Keywords: apoptosis; cancer; cell cycle; DNA damage; metabolic diseases; oxidative stress; senolysis; senescence; therapeutic approach

(This special issue belongs to the Section Cellular Aging)

Macrophage Activation and Regulation

edited by Subhankar Mukhopadhyay

submission deadline 31 Oct 2024 | 4 articles | Viewed by 5110 | Submission Open

Keywords: macrophage activation; classical and alternative activation; M1 and M2 activation; inflammatory and regulatory cytokines; inflammatory and pro-resolution lipid mediators; immune activatory and inhibitory receptors; ITAM and ITIMs

(This special issue belongs to the Section Cellular Immunology)

Cellular and Molecular Mechanisms in Reproductive System Diseases

edited by Arnab Ghosh,

Majid E Warkiani

and Sujoy K. Dhara

submission deadline 31 Oct 2024 | 2 articles | Viewed by 4167 | Submission Open

Keywords: male reproductive system; female reproductive system; hormonal regulation; reproductive immunology; adverse pregnancy outcomes; infertility; sexually transmitted infections (STIs)

(This special issue belongs to the Section Reproductive Cells and Development)

Second Edition of Mesenchymal Stem Cells: Intrinsic/Extrinsic Factors Regulating Stemness, Growth, and Differentiation

edited by

Federica Facchin

and

Francesco Alviano

submission deadline 31 Oct 2024 | 2 articles | Viewed by 3710 | Submission Open

Keywords: tissue-specific mesenchymal stem cells; factors; stemness; growth; differentiation; tissue engineering; regenerative medicine

(This special issue belongs to the Section Stem Cells)

Advances in the Biogenesis, Biology, and Functions of Noncoding RNAs

edited by Xinguo Chen

submission deadline 31 Oct 2024 | 2 articles | Viewed by 2812 | Submission Open

Keywords: noncoding RNA biogenesis; long noncoding RNA (lncRNAs); circular RNA (circRNAs); enhancer RNA (eRNAs); microRNA (miRNAs); PIWI-interacting RNAs (pi-RNAs); tRNA-derived fragments (tRFs)

(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)

Onco-Hematology and Immunotherapy

edited by

Jean Gabert

and Régis T. Costello

submission deadline 31 Oct 2024 | 2 articles | Viewed by 2407 | Submission Open

Keywords: immunotherapy; onco-hematology; CAR T cells; NK cells; immune system; immune cells; leukemias; lymphomas

(This special issue belongs to the Section Cellular Immunology)

Advancements in Cellular Immunotherapies in the Immune Checkpoint Inhibitor Era for Cancer Treatment

edited by

Andrés Tittarelli

and

Flavio Salazar-Onfray

submission deadline 31 Oct 2024 | 1 articles | Viewed by 2139 | Submission Open

Keywords: CAR-T cells; NK-cell immunotherapy; adoptive T-cell transfer; dendritic cell cancer vaccines; whole-tumor-cell vaccines

(This special issue belongs to the Section Cellular Immunology)

State of the Art and Future Prospects in Stem Cell Transplantation

edited by Shin Mineishi

submission deadline 31 Oct 2024 | 1 articles | Viewed by 1979 | Submission Open

Keywords: hematopoietic stem cell transplantation; conditioning; graft-versus-host disease; minimal residual disease; HSCT

(This special issue belongs to the Section Stem Cells)

Onco-Cardiologic Aspects of Chronic Heart Failure: Novel Molecular Mechanisms and Pharmacologic Treatment Options

edited by

Márta Sárközy

and

Renáta Minorics

submission deadline 31 Oct 2024 | 1 articles | Viewed by 1977 | Submission Open

Keywords: chronic heart failure; cardiac remodeling; heart failure therapy; cardiovascular diseases; cancer management; cardiovascular risk factors; onco-cardiology

(This special issue belongs to the Section Cellular Pathology)

Drosophila Model in Molecular Mechanisms of Kidney Dysfunction

edited by Junyi Zhu

submission deadline 31 Oct 2024 | 2 articles | Viewed by 1375 | Submission Open

Keywords: Drosophila; kidney dysfunction; disease processes; gene function; kidney development; signaling; cell biology

(This special issue belongs to the Section Tissues and Organs)

Effects and Mechanisms of Environmental Toxicants on Germ Cells, Gonads, Embryos and Stem Cells —Series 2

edited by

Silvia Garagna

Maurizio Zuccotti

Danilo Cimadomo

and Giulia Fiorentino

submission deadline 31 Oct 2024 | 1 articles | Viewed by 1341 | Submission Open

Keywords: environmental toxicants; gonadal steroid hormones; ovary; folliculogenesis; oogenesis and oocyte; testis; spermatogenesis and sperm; embryo development; epigenetics; omics; cells lines and stem cells; embryoid bodies; gastruloids and organoids; 3D cell culture and imaging

(This special issue belongs to the Section Stem Cells)

The Research on Neuroscience in C. elegans

edited by

Kyung Won Kim

Myon Hee Lee

and Salvatore J. Cherra, III

submission deadline 31 Oct 2024 | 1 articles | Viewed by 1230 | Submission Open

Keywords: new technology for neuroscience; neurodevelopment; synapse development; neuromuscular function; neurotoxicity; neuronal regeneration and degeneration; learning and memory; transgenerational memory; neuronal disorder modeling; communication between neuron and non-neuronal tissues; drug screening

(This special issue belongs to the Section Cells of the Nervous System)

Advances in Biophysics of Cellular Membranes

edited by

Péter Viktor Nagy

and

György Vámosi

submission deadline 31 Oct 2024 | 2 articles | Viewed by 1201 | Submission Open

Keywords: experimental and theoretical membrane research; membrane proteins; non-bilayer membrane structures; extracellular vesicles; membrane active peptides; cell penetrating peptides; membrane mimetics; lipid– protein interactions; membrane curvature; membrane dynamics

(This special issue belongs to the Section Cellular Biophysics)

Patterns across Developmental Scales

edited by

Marisa M. Merino

and

José A. García-Sanz

submission deadline 31 Oct 2024 | 1 articles | Viewed by 1116 | Submission Open

Keywords: patterning; organ; cells; differentiation; proliferation; death; biophysics

Chromosomal Instability in Health and Disease

edited by Anna V. Roschke

submission deadline 31 Oct 2024 | 1 articles | Viewed by 937 | Submission Open

Keywords: chromosomal instability; aneuploidy; polyploidy; cancer evolution; chromosomal instability and aneuploidy in embryonic development; chromosomal instability and polyploidy in evolutionary process; somatic aneuploidy in senescence and ageing

(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)

The Role of Inflammation in AMD (Multifactorial Age-Related Macular Degeneration)—Volume II

edited by Kai Kaarniranta,

Anu Kauppinen

and

Heping Xu

submission deadline 31 Oct 2024 | 1 articles | Viewed by 935 | Submission Open

Keywords: aging; autophagy; degeneration; inflammation; macula; oxidative stress; retina

(This special issue belongs to the Section Cellular Immunology)

Adenosine and Purinergic Receptors: Regulation and Essential Role in Human Disease

edited by Veronica Salmaso,

Stephanie Federico

and

Stefano Moro

submission deadline 31 Oct 2024 | 1 articles | Viewed by 777 | Submission Open

Keywords: adenosine receptors; adenosine; purinergic signaling; P2 receptors; GPCRs; neurodegeneration; cancer; pain; inflammation; ischemia

(This special issue belongs to the Section Cellular Pathology)

Immunopathogenesis and Therapies of Granulomatous Diseases

edited by Shaikh Muhammad Atif

submission deadline 31 Oct 2024 | 1 articles | Viewed by 710 | Submission Open

Keywords: Granulomatous diseases; tuberculosis; sarcoidosis; chronic beryllium disease (CBD); Crohn's disease; immune cells; genetics; environmental exposures；therapeutic approaches

(This special issue belongs to the Section Cellular Immunology)

The Role of Mitochondria in Cell Development and Regeneration

edited by

Kenny Rodriguez-Wallberg

and

Xia Hao

submission deadline 31 Oct 2024 | Viewed by 463 | Submission Open

Keywords: mitochondria; fusion and fission; mtDNA; programmed cell death; cell development; mitochondria-ER contact; organelle

(This special issue belongs to the Section Intracellular and Plasma Membranes)

Ion Channel Involvement in Neurological and Neuromuscular Disorders

edited by

Elena Conte

and

Concetta Altamura

submission deadline 31 Oct 2024 | 1 articles | Viewed by 454 | Submission Open

Keywords: ion channels; neurological diseases; neuromuscular diseases; personalized therapy

(This special issue belongs to the Section Cells of the Nervous System)

Cell-to-Cell Crosstalk as a Target of Therapies

edited by

Agnieszka Gizak

and

Dominika Drulis-Fajdasz

submission deadline 31 Oct 2024 | Viewed by 321 | Submission Open

Keywords: cell-to-cell crosstalk; cellular communication; microenvironment; extracellular vesicles; diagnostic tools; membrane nanotubes; pathogenesis; therapy; cell metabolism; homeostasis

Sebaceous Gland in Skin Health and Disease

edited by

Stefania Briganti

and Monica Ottaviani

submission deadline 31 Oct 2024 | Viewed by 274 | Submission Open

Keywords: sebaceous gland; sebocytes; sebaceous lipid; sebum; inflammation; sebaceous gland disease; skin diseases; pathophysiology; biomarkers; therapeutics

(This special issue belongs to the Section Cellular Pathology)

Emerging Insights into Natural Killer Cell Immunity in Infection and Cancer

edited by Sumit Sen Santara,

Engin Berber

, Weshely Kujur and Sachin Mulik

submission deadline 31 Oct 2024 | Viewed by 253 | Submission Open

Keywords: CAR NK cells; cancer immunotherapy; cell therapy; viral infection; memory NK cells; NK cell targeted therapies; NK-immune cell crosstalk; exosomes

(This special issue belongs to the Section Cellular Immunology)

Cardiac and Neuromuscular Channelopathies: Cellular and Molecular Mechanisms

edited by

Coeli M. Lopes

submission deadline 31 Oct 2024 | Viewed by 223 | Submission Open

Keywords: long QT syndrome; short QT syndrome; Brugada syndrome; myotonia; ALS; CMT; multiple sclerosis; myopathy; neuropathy; periodic paralysis; malignant hyperthermia

(This special issue belongs to the Section Cellular Pathology)

Molecular Insights into Systemic Lupus Erythematosus Pathogenesis: From Genes to Immune Signaling

edited by Shunichi Shiozawa

submission deadline 31 Oct 2024 | Viewed by 222 | Submission Open

Keywords: SLE; pathogenesis; cause; infectious; TCR revision

(This special issue belongs to the Section Cellular Pathology)

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