Cellular and Molecular Mechanisms of Liver Diseases
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Pathology".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 4010
Special Issue Editor
Special Issue Information
Dear Colleagues,
The liver is the largest internal organ and gland in the human body. It performs many vital functions to keep the body pure from toxins and harmful substances; thus, it is considered a central organ for metabolic homeostasis. Liver diseases account for two million deaths annually. The major risk factors include prolonged excessive alcohol consumption, chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections, autoimmune hepatitis, drug-induced liver injury, diabetes mellitus, obesity, and other metabolic diseases.
Liver injury induced by these risk factors is often reversible at early stages since normally quiescent hepatocytes can proliferate and restore normal liver mass and functions. However, persistent injury increases cellular damage, oxidative stress, and inflammation, which can lead to liver fibrosis, progress to cirrhosis, and may ultimately result in liver cancer. In addition, genetic and epigenetic alterations are involved in the development and progression of liver diseases.
This Special Issue will publish original articles and review articles in basic, translational research concerning Cellular and Molecular Mechanisms of all aspects of liver diseases.
Dr. Jieyun Jiang
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- liver
- alcoholic liver disease (ALD)
- viral hepatitis
- metabolic associated steatotic liver disease (MASLD)
- autoimmune hepatitis
- drug-induced liver injury
- liver fibrosis and cirrhosis
- liver cancer
- cellular and molecular mechanisms
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
