Circadian Rhythms in Action: Cellular and Molecular Mechanisms Revealed by Model Organisms
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 31 May 2026 | Viewed by 25
Special Issue Editor
Interests: circadian rhythms; cardiometabolic disorders; dysmetabolism; muscular dystrophy; aging; time-restricted feeding; proteinopathy; aggregation
Special Issue Information
Dear Colleagues,
The Special Issue invites contributions that investigate the intricate mechanisms by which circadian clocks regulate cellular and physiological processes. Model organisms have long provided powerful systems for uncovering fundamental principles of circadian biology, offering unique opportunities to dissect genetic, molecular, metabolic, and physiological pathways with direct relevance to human health. An emerging area of particular interest is the circadian regulation of time-restricted feeding (TRF). TRF aligns nutrient intake with internal clocks to enhance metabolic fitness, delay aging, and protect against cardiometabolic and neurodegenerative disorders. Research in flies, mice, and humans demonstrates that TRF not only synchronizes peripheral clocks but also uncovers novel regulatory networks linking diet, circadian rhythms, and systemic health.
This Special Issue will feature original research articles, reviews, and perspectives that address how circadian regulation shapes metabolism, cardiovascular function, neurodegeneration, sleep, and aging. By emphasizing conserved mechanisms, innovative methodologies, and translational potential, this collection seeks to inspire cross-disciplinary dialog and highlight novel opportunities for therapeutic intervention. Ultimately, the goal is to integrate insights from diverse model systems to advance our understanding of circadian biology and its critical role in maintaining health across the lifespan.
Dr. Girish Chandra Melkani
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- circadian rhythm
- molecular regulation
- cellular mechanisms
- model organisms
- time-restricted feeding
- metabolism
- aging
- neurodegeneration
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