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Most Cited

  • Review
  • Open Access
790 Citations
100,610 Views
25 Pages

Next-Generation Sequencing Technology: Current Trends and Advancements

  • Heena Satam,
  • Kandarp Joshi,
  • Upasana Mangrolia,
  • Sanober Waghoo,
  • Gulnaz Zaidi,
  • Shravani Rawool,
  • Ritesh P. Thakare,
  • Shahid Banday,
  • Alok K. Mishra and
  • Gautam Das
  • + 1 author

13 July 2023

The advent of next-generation sequencing (NGS) has brought about a paradigm shift in genomics research, offering unparalleled capabilities for analyzing DNA and RNA molecules in a high-throughput and cost-effective manner. This transformative technol...

  • Review
  • Open Access
167 Citations
19,425 Views
39 Pages

29 January 2024

The extracellular enzymes secreted by soil microorganisms play a pivotal role in the decomposition of organic matter and the global cycles of carbon (C), phosphorus (P), and nitrogen (N), also serving as indicators of soil health and fertility. Curre...

  • Review
  • Open Access
140 Citations
24,983 Views
29 Pages

22 July 2023

The emergence and rapid development of deep learning, specifically transformer-based architectures and attention mechanisms, have had transformative implications across several domains, including bioinformatics and genome data analysis. The analogous...

  • Review
  • Open Access
138 Citations
13,967 Views
29 Pages

Extracellular Vesicles: New Classification and Tumor Immunosuppression

  • Mona Sheta,
  • Eman A. Taha,
  • Yanyin Lu and
  • Takanori Eguchi

10 January 2023

Extracellular vesicles (EVs) are cell-derived membrane-surrounded vesicles carrying various types of molecules. These EV cargoes are often used as pathophysiological biomarkers and delivered to recipient cells whose fates are often altered in local a...

  • Review
  • Open Access
101 Citations
23,243 Views
43 Pages

Targets of Immune Escape Mechanisms in Cancer: Basis for Development and Evolution of Cancer Immune Checkpoint Inhibitors

  • Shovan Dutta,
  • Anirban Ganguly,
  • Kaushiki Chatterjee,
  • Sheila Spada and
  • Sumit Mukherjee

30 January 2023

Immune checkpoint blockade (ICB) has emerged as a novel therapeutic tool for cancer therapy in the last decade. Unfortunately, a small number of patients benefit from approved immune checkpoint inhibitors (ICIs). Therefore, multiple studies are being...

  • Review
  • Open Access
99 Citations
22,212 Views
19 Pages

General Overview of Klebsiella pneumonia: Epidemiology and the Role of Siderophores in Its Pathogenicity

  • Rim Abbas,
  • Mohamed Chakkour,
  • Hiba Zein El Dine,
  • Eseiwi Folorunsho Obaseki,
  • Soumaya T. Obeid,
  • Aya Jezzini,
  • Ghassan Ghssein and
  • Zeinab Ezzeddine

27 January 2024

The opportunistic pathogen Klebsiella pneumoniae (K. pneumoniae) can colonize mucosal surfaces and spread from mucosae to other tissues, causing fatal infections. Medical equipment and the healthcare setting can become colonized by Klebsiella species...

  • Review
  • Open Access
92 Citations
17,462 Views
17 Pages

Unsaturated Fatty Acids and Their Immunomodulatory Properties

  • Salvatore Coniglio,
  • Maria Shumskaya and
  • Evros Vassiliou

9 February 2023

Oils are an essential part of the human diet and are primarily derived from plant (or sometimes fish) sources. Several of them exhibit anti-inflammatory properties. Specific diets, such as Mediterranean diet, that are high in ω-3 polyunsaturate...

  • Review
  • Open Access
91 Citations
6,096 Views
16 Pages

Exploring the Impact of Contaminants of Emerging Concern on Fish and Invertebrates Physiology in the Mediterranean Sea

  • Federica Impellitteri,
  • Cristiana Roberta Multisanti,
  • Polina Rusanova,
  • Giuseppe Piccione,
  • Francesca Falco and
  • Caterina Faggio

24 May 2023

In this historical context, the Mediterranean Sea faces an increasing threat from emerging pollutants such as pharmaceuticals, personal care products, heavy metals, pesticides and microplastics, which pose a serious risk to the environment and human...

  • Review
  • Open Access
90 Citations
16,274 Views
19 Pages

Bacterial Biofilm in Chronic Wounds and Possible Therapeutic Approaches

  • Ilaria Cavallo,
  • Francesca Sivori,
  • Arianna Mastrofrancesco,
  • Elva Abril,
  • Martina Pontone,
  • Enea Gino Di Domenico and
  • Fulvia Pimpinelli

9 February 2024

Wound repair and skin regeneration is a very complex orchestrated process that is generally composed of four phases: hemostasis, inflammation, proliferation, and remodeling. Each phase involves the activation of different cells and the production of...

  • Review
  • Open Access
86 Citations
15,227 Views
18 Pages

2 February 2024

Soil-beneficial microbes in the rhizosphere play important roles in improving plant growth and health. Root exudates play key roles in plant–microbe interactions and rhizobacterial colonization. This review describes the factors influencing the...

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Biology - ISSN 2079-7737