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Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Leishmaniasis and Chagas Disease: Biology, Epidemiology, Treatment and Control

edited by

Fernando Almeida-Souza

Flávia de Oliveira Cardoso

and

Kátia Da Silva Calabrese

submission deadline 15 Aug 2025 | 8 articles | Viewed by 16137 | Submission Open

Keywords: Leishmaniasis; Chagas disease; immunopathogeny; diagnosis; epidemiology; control; clinical studies; treatment; vaccine

(This special issue belongs to the Section Microbiology)

Animal Models of Arthritis

edited by Nevena Arsenović-Ranin and Biljana Bufan

submission deadline 30 Aug 2025 | 4 articles | Viewed by 8087 | Submission Open

Keywords: animal models; rheumatoid arthritis; osteoarthritis; inflammation; immunopathology; pathological features; joints; treatment; drug screening; traditional medicine

(This special issue belongs to the Section Medical Biology)

Metabolic and Stress Responses in Aquatic Animals

edited by

Marcelino Herrera

, Laura Fernández-Alacid and

Ignacio Ruiz-Jarabo

submission deadline 31 Aug 2025 | 13 articles | Viewed by 22493 | Submission Open

Keywords: stress; metabolism; animal welfare; aquaculture; cephalopods; fish; molluscs; crustaceans; aquatic animals; animal physiology

(This special issue belongs to the Section Zoology)

The Replication Licensing System

edited by

Peter J. Gillespie

submission deadline 31 Aug 2025 | 6 articles | Viewed by 21271 | Submission Open

Keywords: cell cycle; DNA replication; genome stability; replication licensing; MCM2-7; ORC; Cdc6; CDT1; cancer; Meier-Gorlin syndrome

(This special issue belongs to the Section Cell Biology)

Infectious Diseases: Emerging Diagnostic Methods, Updated Treatment Protocols and New Antimicrobial Agents

edited by

Andreas G. Tsantes

Dimitrios V. Papadopoulos

Rozeta Sokou

and

Vanesa Bellou

submission deadline 31 Aug 2025 | 6 articles | Viewed by 20197 | Submission Open

Keywords: infectious diseases; pathophysiology; risk factors; prognosis; diagnostic methods; biomarkers; molecular techniques; treatment protocols; novel antibiotic

(This special issue belongs to the Section Infection Biology)

Editorial Board Members' Collection Series: “Biodiversity and Ecosystem Function under Global Change”

edited by

Shucun Sun

and

Panayiotis G. Dimitrakopoulos

submission deadline 31 Aug 2025 | 9 articles | Viewed by 19191 | Submission Open

Keywords: climate change; global warming; precipitation; N deposition; biological invasion; species interaction; microbial process; ecosystem function; ecosystem service

2nd Edition: Aquatic Alien Invasions and Their Impact on Biodiversity and Ecosystem Services

edited by

Paraskevi K. Karachle

Elena Tricarico

Giorgio Mancinelli

and

Baran Yoğurtçuoğlu

submission deadline 31 Aug 2025 | 8 articles | Viewed by 15906 | Submission Open

Keywords: species; aquatic invasions; biodiversity; ecosystem services; conservation

(This special issue belongs to the Section Marine Biology)

The Effect of Food- and Nutrient-Derived Molecules on Cells and Tissue

edited by

Roberta Moschini

and

Francesca Felice

submission deadline 31 Aug 2025 | 4 articles | Viewed by 13735 | Submission Open

Keywords: natural products; molecules; nutrition; antioxidants; cell biology; metabolism

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Pollination Biology

edited by

Yu Gao

submission deadline 31 Aug 2025 | 8 articles | Viewed by 11673 | Submission Open

Keywords: conservation biology; insect diversity; pollinator-plant interactions; ecosystem service; pollinator insect

(This special issue belongs to the Section Ecology)

Editorial Board Members’ Collection Series: Pathology of Cancer and Cardiovascular Disease

edited by

Mridula Chopra

Helen L. Fillmore

and

Maurizio Forte

submission deadline 31 Aug 2025 | 2 articles | Viewed by 6736 | Submission Open

Keywords: cancer; cardiovascular disease; biomarkers; gut microbiome; inflammation; health policy; diet and lifestyle

Biology, Ecology and Management of Harmful Algae

edited by Paul V. Zimba and

Jabulani R. Gumbo

submission deadline 31 Aug 2025 | 4 articles | Viewed by 6261 | Submission Open

Keywords: harmful algae; toxic algae; harmful algal bloom (HAB); excessive algae growth; microalgae and macroalgae; cyanobacteria; dinoflagellates; toxins; water quality; phytoplankton; water resources

Lipid Metabolism in Plant Growth and Development

edited by Xiaohong Yu and Yingqi Cai

submission deadline 31 Aug 2025 | 1 articles | Viewed by 3124 | Submission Open

Keywords: lipid metabolism; lipid engineering; plant growth; plant development; lipid biosynthesis; lipid signaling; lipid transport; membrane structure; energy storage; plant– microbe interactions; stress response; nutrition value; cellular process

(This special issue belongs to the Section Plant Science)

Molecular Basis of Seed Germination and Dormancy

edited by

Yifeng Wang

Jiezheng Ying

Xiaohong Tong

and Yu Cheng

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1712 | Submission Open

Keywords: molecular mechanism; genetic basis; seed germination; dormancy; genetic improvement

(This special issue belongs to the Section Plant Science)

Gene Editing and Genetic Regulation: New Insight in Insect Sex Determination, Reproductive Development and Pest Control

edited by Honglun Bi

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1301 | Submission Open

Keywords: insect gene editing; genetic regulation ; CRISPR/Cas ; gene drive ; pest control; sex determination ; reproductive development; insect sterile technique

(This special issue belongs to the Section Zoology)

Redox Signaling and Oxidative Stress in Health and Disease

edited by

Taeho Kwon

and

Hu-Nan Sun

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1172 | Submission Open

Keywords: redox signaling; oxidative stress; antioxidant defense; cellular regulation; aging; cancer; cardiovascular diseases; neurodegenerative diseases; therapeutic approaches; digital biotechnology

(This special issue belongs to the Section Cell Biology)

Airway Smooth Muscle and Respiratory Diseases

edited by

Joseph Jude

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1161 | Submission Open

Keywords: airway; airway smooth muscle; asthma; COPD; airway hyperresponsiveness; airway inflammation; airway remodeling; bronchospasm; bronchodilators

(This special issue belongs to the Section Cell Biology)

Disease Biomarker Discovery and Validation

edited by Matthew James Jennings

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1098 | Submission Open

Keywords: biomarkers; prognostic validation; predictive validation; analytical validation

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Adaptation Mechanisms of Forest Trees to Abiotic Stress

edited by

Ling Yang

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1066 | Submission Open

Keywords: genetic variation; epigenetic control; plant hormone; nitric oxide; reactive oxygen species; phenomic; metabolomic; genomic; signal transduction; gene function

(This special issue belongs to the Section Plant Science)

Regenerative Biology: Regeneration After Spinal Cord and Peripheral Nerve Injury

edited by

Alexandre Leite Rodrigues de Oliveira

submission deadline 31 Aug 2025 | 1 articles | Viewed by 869 | Submission Open

Keywords: neuronal regeneration; peripheral nerve repair; spinal cord injury; axonal growth; neuroplasticity; glial cells; molecular signaling pathways; stem cells in nerve regeneration; neuroinflammation; animal models of nerve injury

(This special issue belongs to the Section Neuroscience)

Cellular and Molecular Biology of Liver Diseases

edited by Matthew McMillin

submission deadline 31 Aug 2025 | Viewed by 341 | Submission Open

Keywords: drug-induced liver injury; cholestasis; hepatitis; metabolic dysfunction-associated steatotic liver disease; alcohol-associated liver disease

(This special issue belongs to the Section Cell Biology)

Biomarkers for Cancer Immunity

edited by Xuyao Zhang

submission deadline 31 Aug 2025 | Viewed by 282 | Submission Open

Keywords: tumor microenvironment; tumor immunity; systems immunology; resistance mechanism; biomarkers

Microbiology and Metabolomics in Reproductive Biology

edited by

Giuseppina Campisciano

submission deadline 31 Aug 2025 | Viewed by 281 | Submission Open

Keywords: maternal microbiome; metabolome; pregnancy outcomes; fetal development; biomarkers; immune function; metabolic health; disease prediction; therapeutic interventions; maternal and child health

(This special issue belongs to the Section Developmental and Reproductive Biology)

Intermolecular Interactions in Cytochrome P450 Systems

edited by

Dmitri Davydov

and John Hackett

submission deadline 31 Aug 2025 | Viewed by 226 | Submission Open

Keywords: cytochrome P450; NADPH-cytochrome P450 reductase; cytochrome b5; adrenodoxin; microsomes; protein– protein interactions; protein-lipid interactions; systems biochemistry of drug metabolism; cytochrome P450-dependent signaling

(This special issue belongs to the Section Biochemistry and Molecular Biology)

The Regulation of Glucose Homeostasis

edited by Aaron Aykut Uner

submission deadline 31 Aug 2025 | Viewed by 225 | Submission Open

Keywords: glucose homeostasis; brain; type 1 diabetes; type 2 diabetes; insulin sensitivity; beta-cell regeneration

(This special issue belongs to the Section Physiology)

Biological Advances in Pluripotent Stem Cells

edited by

Thomas Hollemann

and Matthias Jung

submission deadline 31 Aug 2025 | Viewed by 184 | Submission Open

Keywords: induced pluripotent stem cell; embryonic stem cell; regenerative medicine; drug research; organoid; translational biology

(This special issue belongs to the Section Cell Biology)

Biosynthesis of Metabolites from Microorganisms, or Microorganism-Host Interaction? (Volume II)

edited by

Fengli Zhang

Zhiqiang Liu

and

Michel Denis

submission deadline 1 Sep 2025 | 5 articles | Viewed by 13069 | Submission Open

Keywords: biosynthesis; biological activity; biosynthesis regulation; microbial metabolites; microbe– host reaction

(This special issue belongs to the Section Microbiology)

Feature Papers on Developmental and Reproductive Biology

edited by

Jacek Z. Kubiak

submission deadline 15 Sep 2025 | 6 articles | Viewed by 13736 | Submission Open

Keywords: embryo/fetus development; reproductive biology; gametogenesis; differentiation; growth; homeostasis; regeneration; aging; cell cycle regulation; stem cells; organoids

(This special issue belongs to the Section Developmental and Reproductive Biology)

Biological Rhythms and Molecular Clockworks in Physiology and Pathology

edited by

Gianluigi Ubaldo Mazzoccoli

and

Marina Maria Bellet

submission deadline 30 Sep 2025 | 10 articles | Viewed by 29932 | Submission Open

Keywords: biological rhythms; molecular clockworks; circadian timing system; circadian desynchrony; circadian disruption; chronopathology; chronopharmacology and chronotherapeutics; chronomedicine

(This special issue belongs to the Section Physiology)

Artificial Intelligence Research for Complex Biological Systems

edited by

Yong Chen

and

Milana Frenkel-Morgenstern

submission deadline 30 Sep 2025 | 6 articles | Viewed by 6090 | Submission Open

Keywords: deep learning; generative artificial intelligence; bioinformatics; complex biological systems; cancer; neuroscience; next-generation sequencing; single-cell and bulk omics; genomics

(This special issue belongs to the Section Bioinformatics)

Plant Breeding: From Biology to Biotechnology

edited by Juwu Gong

submission deadline 30 Sep 2025 | 5 articles | Viewed by 5577 | Submission Open

Keywords: plant breeding; biotechnology; molecular marker-assisted selection; genetic engineering; genome editing; tissue culture; phenotype; genetics; omics

(This special issue belongs to the Section Biotechnology)

Molecular Basis of Bone Homeostasis and Skeletal Diseases

edited by

Weirong Xing

submission deadline 30 Sep 2025 | 3 articles | Viewed by 4435 | Submission Open

Keywords: osteoclast; osteoblast; bone; skeletal disease; bone formation; bone resorption; osteoporosis; osteopetrosis; human genetics; mouse genetics

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Research Advancements in Oral Biology

edited by

Jelena R. Roganović

and Nina Petrović

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1754 | Submission Open

Keywords: oral biology; oral tissue regeneration; artificial intelligence (AI) in dentistry; genomics and proteomics in dentistry; dental research; salivary diagnostics

(This special issue belongs to the Section Medical Biology)

Research Progress on Melanocytes and Melanin

edited by Zeina Tannous

submission deadline 30 Sep 2025 | Viewed by 372 | Submission Open

Keywords: melanin; melanocytes; melanocyte stem cell; pigmentation; melanoma; dysplastic nevi; vitiligo; melasma

(This special issue belongs to the Section Medical Biology)

Molecular Mechanisms of Cell Signal Transduction

edited by Wenjing Zhang

submission deadline 30 Sep 2025 | Viewed by 244 | Submission Open

Keywords: molecular interactions in signaling; phosphorylation and signal propagation; post-translational modifications; cross-talk between signaling pathways; cellular response to extracellular stimuli; metabolic regulation and signaling; signaling in cancer progression; inflammatory signaling pathways; role of signaling in stem cell differentiation; innovative imaging techniques for signaling

(This special issue belongs to the Section Cell Biology)

The Role of Innate Immunity in Organ Transplantation

edited by Todd V. Brennan

submission deadline 30 Sep 2025 | Viewed by 240 | Submission Open

Keywords: innate immunity; allograft rejection; transplantation; immune tolerance

(This special issue belongs to the Section Medical Biology)

Island Ecology and Biodiversity: Managing the Effects of Climate and Land-Use Change

edited by Kealohanuiopuna Mark Kinney and Susan Cordell

submission deadline 30 Sep 2025 | Viewed by 227 | Submission Open

Keywords: island biogeography; biodiversity conservation; invasive species management; biocultural approaches; ecosystem resilience; landscape ecology; environmental sustainability; climate adaptation; social– ecological systems; restoration ecology TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian // TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back // This page is in English Translate to Simplified Chinese Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com

(This special issue belongs to the Section Ecology)

Physiology and Ecology of Animal Parasites and Related Diseases

edited by Marcela K. Castelo

submission deadline 30 Sep 2025 | Viewed by 225 | Submission Open

Keywords: parasites; parasitoids; physiology; ecology; ecophysiology; diseases; global change

(This special issue belongs to the Section Zoology)

Metabolic Interactions between the Gut Microbiome and Host

edited by

Weiwei Wang

and

Yun Ji

submission deadline 30 Oct 2025 | 6 articles | Viewed by 9899 | Submission Open

Keywords: gut microbiome; host; metabolome; microbial heterogeneity; biomolecules

(This special issue belongs to the Section Microbiology)

Multi-omics Approaches in Agricultural Crops to Unravel Responses to Environmental Stresses and Advance Sustainable Agriculture

edited by

Vito Butardo

submission deadline 30 Oct 2025 | 2 articles | Viewed by 2649 | Submission Open

Keywords: plant functional genomics; environmental stress; climate change; crop yield; crop quality; nutritional properties; omics approaches; genomics; transcriptomics; proteomics; metabolomics; epigenomics; phenomics; stress-tolerant crops; breeding strategies; data integration; systems biology; sustainable agriculture; underutilized crops; orphan crops; beneficial microorganisms

(This special issue belongs to the Section Plant Science)

Pathophysiology of Hearing Loss

edited by Charles E. Bishop

submission deadline 30 Oct 2025 | Viewed by 213 | Submission Open

Keywords: hearing loss; cochlea; noise; deafness genes; cell death; hair cells; inner ear; biotoxicity; metabolic risk; gene mutation; physiology and pathophysiology; animal models; biomarkers and molecular mechanisms

(This special issue belongs to the Section Physiology)

Advances in the Fields of Neurotrauma and Neuroregeneration

edited by

Alexander Younsi

Guoli Zheng

and

Xing Cheng

submission deadline 31 Oct 2025 | 8 articles | Viewed by 41435 | Submission Open

Keywords: neurotrauma; spinal cord injury; traumatic brain injury; neuropathic pain; neuroinflammation; axonal regeneration; postinjury plasticity; neurorehabilitation; cell transplantation

(This special issue belongs to the Section Neuroscience)

Young Researchers in Neuroscience

edited by Yansheng Du

submission deadline 31 Oct 2025 | 2 articles | Viewed by 16339 | Submission Open

Keywords: neurobiology; cell biology; molecular mechanisms; neural development; synaptic function; ion channels; neurotransmitter systems; gene expression; neuronal signaling; cellular physiology

(This special issue belongs to the Section Neuroscience)

Immunosenescence and Its Modification by Interventions

edited by

Andreas Meryk

and Luca Pangrazzi

submission deadline 31 Oct 2025 | 1 articles | Viewed by 4042 | Submission Open

Keywords: immunosenescence; aging immune system; inflammaging; vaccine efficacy in elderly; nutritional immunomodulation; exercise and immunity; senolytic therapies; T-cell exhaustion; thymic rejuvenation; age-related diseases

(This special issue belongs to the Section Immunology)

Progress in Wildlife Conservation, Management and Biological Research

edited by Ana Carolina Srbek-Araujo

submission deadline 31 Oct 2025 | 4 articles | Viewed by 3051 | Submission Open

Keywords: adaptive capacity; climate change; conservation opportunities; species vulnerability; threatened species; wildlife conservation; wildlife management

(This special issue belongs to the Section Conservation Biology and Biodiversity)

Pathogen-Host Interaction and Vaccine/Drug Design

edited by Iga Kucharska

submission deadline 31 Oct 2025 | 1 articles | Viewed by 2379 | Submission Open

Keywords: infectious diseases; host– pathogen interactions; vaccine; drug design; immune evasion; immunogen

(This special issue belongs to the Section Medical Biology)

Advances in Omics Approaches for Understanding Metabolic Disorders: Environmental and Nutritional Perspectives

edited by Yue Ge

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1003 | Submission Open

Keywords: metabolic disorders; environmental exposures; nutritional factors; omics technologies; co-exposures; cumulative toxicity; metabolic pathways; human health risk assessment; advanced in vitro models; systems toxicology

(This special issue belongs to the Section Physiology)

Advancing Crop Nutritional Quality Through Genomic Approaches

edited by Gen Xu

submission deadline 31 Oct 2025 | 1 articles | Viewed by 509 | Submission Open

Keywords: crop improvement; genomics; multi-omics; genetic loci; breeding

(This special issue belongs to the Section Plant Science)

Extracellular Vesicles: Biogenesis and Functions in the Complex Landscape of Differentiation and Disease

edited by

Sorina Dinescu

submission deadline 31 Oct 2025 | Viewed by 443 | Submission Open

Keywords: stem cell biology; stem cell differentiation; adipogenesis; neurogenesis; extracellular vesicles in stem cell differentiation; ncRNAs; tumor microenvironment; intercellular communication

(This special issue belongs to the Section Cell Biology)

Plant-Microbe Interaction: The Cellular Mechanism Influence Plant Health

edited by

Wei Zhang

and Gongjun Shi

submission deadline 31 Oct 2025 | Viewed by 348 | Submission Open

Keywords: plant-microbe interaction; plant health; plant immunity; gene-for-gene model; resistosomes; metabolic crosstalk; climate change

Transcriptional Regulation in Eukaryotes

edited by Anil Kumar Panigrahi

submission deadline 31 Oct 2025 | Viewed by 321 | Submission Open

Keywords: transcription factors (TFs); transcriptional coregulators; RNA polymerase II; chromatin modifications and remodeling; enhancers; silencers; non-coding RNAs; 3D chromatin architecture; multi-omics integration; single-cell technologies

(This special issue belongs to the Section Genetics and Genomics)

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