Special Issues

Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Ferroptosis: Mechanisms and Human Disease
edited by Chan-Yen Kuo
submission deadline 15 Aug 2026 | 5 articles | Viewed by 16602 | Submission Open
Keywords: ferroptosis; systemic diseases; inflammatory response; mitochondrial-dependent redox homeostasis; microenvironment
(This special issue belongs to the Section Cell Biology)
Gut Microbiota in Aquatic Animals Nutrition, Immunity, and Host–Microbe Interactions
edited by Qunlan Zhou
submission deadline 15 Aug 2026 | 3 articles | Viewed by 7669 | Submission Open
Keywords: gut microbiota; aquatic animal health; host–microbe interactions; functional probiotics; immunomodulation; nutrient metabolism; multi-omics integration; microbial ecology; environmental adaptation
(This special issue belongs to the Section Microbiology)
Changing Coral Reef Biodiversity and Function in the Anthropocene
edited by
submission deadline 15 Aug 2026 | 1 articles | Viewed by 2098 | Submission Open
Keywords: anthropogenic stressors; coral reefs; climate change; biodiversity loss; marine conservation; ecological adaptation; ecosystem function; resilience
(This special issue belongs to the Section Marine and Freshwater Biology)
Role of CARD9 in Health and Diseases
edited by Zuberwasim Sayyad and Nikhil Sharma
submission deadline 15 Aug 2026 | Viewed by 783 | Submission Open
Keywords: CARD9; innate immunity; pattern recognition receptors; autophagy; apoptosis; inflammasome; reactive oxygen species; post-translational modifications; gut microbiota; inflammation and cancer
Recent Advances in Angiogenesis and Vascular Development submission deadline 15 Aug 2026 | Viewed by 280 | Submission Open
Keywords: vasculogenesis; angiogenesis; vascular differentiation markers; endothelial-to-mesenchymal transition (EndMT); mechanotransduction; endothelial function; endothelial damage
(This special issue belongs to the Section Cell Biology)
The Role of Autophagy and Macrophages in Modulating Immune Responses in Atherosclerosis
edited by and Aatira Vijay
submission deadline 25 Aug 2026 | Viewed by 798 | Submission Open
Keywords: atherosclerosis; macrophages; autophagy; immune regulation; chronic inflammation; plaque stability; lipid metabolism; efferocytosis; immunometabolism
Population Genetics and Conservation of Amphibians and Reptiles
edited by
submission deadline 25 Aug 2026 | Viewed by 410 | Submission Open
Keywords: conservation genetics; local adaptation; genetic diversity; amphibian; reptile; environmental change
(This special issue belongs to the Section Conservation Biology and Biodiversity)
Animal Models of Arthritis
edited by Nevena Arsenović-Ranin and Biljana Bufan
submission deadline 30 Aug 2026 | 4 articles | Viewed by 16068 | Submission Open
Keywords: animal models; rheumatoid arthritis; osteoarthritis; inflammation; immunopathology; pathological features; joints; treatment; drug screening; traditional medicine
(This special issue belongs to the Section Medical Biology)
Young Researchers in Neuroscience
edited by
submission deadline 31 Aug 2026 | 7 articles | Viewed by 72951 | Submission Open
Keywords: neurobiology; cell biology; molecular mechanisms; neural development; synaptic function; ion channels; neurotransmitter systems; gene expression; neuronal signaling; cellular physiology
(This special issue belongs to the Section Neuroscience)
Bone Cell Biology
edited by Yohei Abe and
submission deadline 31 Aug 2026 | 8 articles | Viewed by 29989 | Submission Open
Keywords: osteoclast; osteoblast; osteocyte; bone density; macrophage; RANK; transcription factor; cell signaling
(This special issue belongs to the Section Cell Biology)
Biology, Ecology and Management of Harmful Algae
edited by Paul V. Zimba and
submission deadline 31 Aug 2026 | 9 articles | Viewed by 17608 | Submission Open
Keywords: harmful algae; toxic algae; harmful algal bloom (HAB); excessive algae growth; microalgae and macroalgae; cyanobacteria; dinoflagellates; toxins; water quality; phytoplankton; water resources
Editorial Board Members’ Collection Series: Pathology of Cancer and Cardiovascular Disease submission deadline 31 Aug 2026 | 3 articles | Viewed by 14325 | Submission Open
Keywords: cancer; cardiovascular disease; biomarkers; gut microbiome; inflammation; health policy; diet and lifestyle
Lipid Metabolism in Plant Growth and Development
edited by Xiaohong Yu and Yingqi Cai
submission deadline 31 Aug 2026 | 3 articles | Viewed by 7307 | Submission Open
Keywords: lipid metabolism; lipid engineering; plant growth; plant development; lipid biosynthesis; lipid signaling; lipid transport; membrane structure; energy storage; plant–microbe interactions; stress response; nutrition value; cellular process
(This special issue belongs to the Section Plant Science)
Advances in Cardiac and Vascular Biology: From Mechanisms to Pathophysiology
edited by and
submission deadline 31 Aug 2026 | 4 articles | Viewed by 5976 | Submission Open
Keywords: cardiovascular biology; molecular mechanisms; cellular signaling; epigenomic regulation; vascular remodeling; metabolic reprogramming; cardiac pathophysiology
(This special issue belongs to the Section Physiology)
Advances in Leishmaniasis and Chagas Disease: Biology, Epidemiology, Treatment and Control (2nd Edition) submission deadline 31 Aug 2026 | 1 articles | Viewed by 5476 | Submission Open
Keywords: leishmaniasis; Chagas disease; immunopathogeny; diagnosis; epidemiology; control; vaccine
Host–Microbiome–Environment Interactions in Domestic and Wild Animals
edited by and Cesar A. Meza-Herrera
submission deadline 31 Aug 2026 | 4 articles | Viewed by 5317 | Submission Open
Keywords: animal microbiome; environmental microbiota; host–microbiota interactions; wildlife microbiology; livestock health and productivity; microbiome and conservation; One Health approach; gut microbiota dynamics; microbial ecology; microbiome and reproduction; habitat–host microbiome linkages; multi-omics integration
(This special issue belongs to the Section Microbiology)
Bone Mechanics: From Cells to Organs to Function submission deadline 31 Aug 2026 | 5 articles | Viewed by 5228 | Submission Open
Keywords: bone mechanics; bone remodeling; mechanotransduction; structural analysis; functional morphology; bioengineering
(This special issue belongs to the Section Physiology)
Mitochondrial Genomics of Arthropods
edited by Renfu Shao
submission deadline 31 Aug 2026 | 5 articles | Viewed by 4565 | Submission Open
Keywords: mitochondrial genome architecture; transcriptional dynamics; translational mechanisms; comparative genomics; molecular evolution; arthropod phylogenetics; systematics; evolutionary biology
(This special issue belongs to the Section Genetics and Genomics)
Cellular and Molecular Biology of Liver Diseases
edited by Matthew McMillin
submission deadline 31 Aug 2026 | 2 articles | Viewed by 4190 | Submission Open
Keywords: drug-induced liver injury; cholestasis; hepatitis; metabolic dysfunction-associated steatotic liver disease; alcohol-associated liver disease
(This special issue belongs to the Section Cell Biology)
Biological Invasions in Freshwater Ecosystems
edited by Filipe Banha
submission deadline 31 Aug 2026 | 2 articles | Viewed by 2299 | Submission Open
Keywords: invasive species; rivers; lakes; ecology; biology; impacts
(This special issue belongs to the Section Conservation Biology and Biodiversity)
Regenerative Biology: Regeneration After Spinal Cord and Peripheral Nerve Injury submission deadline 31 Aug 2026 | 2 articles | Viewed by 2125 | Submission Open
Keywords: neuronal regeneration; peripheral nerve repair; spinal cord injury; axonal growth; neuroplasticity; glial cells; molecular signaling pathways; stem cells in nerve regeneration; neuroinflammation; animal models of nerve injury
(This special issue belongs to the Section Neuroscience)
Energy Metabolism, Genetics and Development in Drosophila
edited by
submission deadline 31 Aug 2026 | 2 articles | Viewed by 1719 | Submission Open
Keywords: Drosophila; energy metabolism; development; epigenetics; non-coding RNAs; metabolic disease; growth; signaling pathway
(This special issue belongs to the Section Bioinformatics)
Current Status and Future Perspectives on Lipid Biology and Beyond submission deadline 31 Aug 2026 | 2 articles | Viewed by 1355 | Submission Open
Keywords: lipids; fatty acids (FAs); omega-3 (FA); omega-6 (FA); cancer; cell biology; oxylipins; oxidative stress; lipidomics; lipid nanoparticles; personalized lipid-based therapies
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Perception in Noise: From Human Perceptive Abilities to Neural Correlates and Computational Models
edited by
submission deadline 31 Aug 2026 | 1 articles | Viewed by 1320 | Submission Open
Keywords: auditory perception; neural networks; communication sounds; auditory system; masking noise; coding in noise; robust representation
(This special issue belongs to the Section Neuroscience)
Fruits and Seeds of Tropical Plants: Conservation of Species, Ecological Importance and Quality Valorization
edited by Edna Ursulino Alves and Silvanda De Melo Silva
submission deadline 31 Aug 2026 | 1 articles | Viewed by 1104 | Submission Open
Keywords: climate change; nature conservation; biodiversity; plant propagation; postharvest quality; metabolic profile; orchard management and quality
(This special issue belongs to the Section Conservation Biology and Biodiversity)
Microbiology and Metabolomics in Reproductive Biology submission deadline 31 Aug 2026 | 1 articles | Viewed by 1076 | Submission Open
Keywords: maternal microbiome; metabolome; pregnancy outcomes; fetal development; biomarkers; immune function; metabolic health; disease prediction; therapeutic interventions; maternal and child health
(This special issue belongs to the Section Developmental and Reproductive Biology)
Novel Mechanisms and Biological Processes in Redox and Inflammatory Signaling
edited by Shengchen Wang and
submission deadline 31 Aug 2026 | 1 articles | Viewed by 960 | Submission Open
Keywords: redox; inflammatory; oxidative stress; antioxidant; anti-inflammatory; signaling pathways
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Biophysics of Exposome: Molecular Mechanisms of Action
edited by and Madhavi K. Ganapathiraju
submission deadline 31 Aug 2026 | Viewed by 895 | Submission Open
Keywords: computational biology; systems biology; mass spectrometry; protein–ligand networks; protein–protein interaction networks; metabolomics; proteomics; surface plasmon resonance; protein structure prediction; molecular docking; target fishing; machine learning; artificial intelligence
Sickle Cell Disease: Molecular Mechanisms, Pathogenesis and Therapies
edited by Chithra Palani
submission deadline 31 Aug 2026 | Viewed by 721 | Submission Open
Keywords: SCD; anemia; erythrocyte development; erythroid progenitors; CD34 cells; vaso-occlusion; pain crisis; hemolysis; oxidative stress; sickling; inflammation; ER stress; fetal hemoglobin; hematopoiesis; ischemia and tissue damage; organ damage; drug development; SCD diagnosis; gene therapy; cell therapy
(This special issue belongs to the Section Medical Biology)
Environmental Factors and Freshwater Organism Responses
edited by and Joana L. Santos
submission deadline 31 Aug 2026 | 1 articles | Viewed by 621 | Submission Open
Keywords: freshwater ecosystems; environmental stressors; climate change; pollution; ecotoxicology; adaptation; phenotypic plasticity; biodiversity; conservation; genomics
(This special issue belongs to the Section Ecology)
Research Progress on Metabolic Pathways in Neurodegenerative Diseases
edited by Ali H. Rafati
submission deadline 31 Aug 2026 | Viewed by 359 | Submission Open
Keywords: neurodegeneration; metabolic dysfunction; mitochondrial impairment; oxidative stress; glucose metabolism; lipid metabolism; autophagy; neuroinflammation; biomarkers; therapeutic targets
(This special issue belongs to the Section Neuroscience)
Uncovering the Role of T Cells in Immune Homeostasis and Immune Tolerance
edited by
submission deadline 31 Aug 2026 | Viewed by 230 | Submission Open
Keywords: regulatory T cells; immune tolerance; FOXP3; cytokine; suppression
(This special issue belongs to the Section Cell Biology)
Biosynthesis of Metabolites from Microorganisms, or Microorganism-Host Interaction? (Volume II) submission deadline 1 Sep 2026 | 8 articles | Viewed by 28118 | Submission Open
Keywords: biosynthesis; biological activity; biosynthesis regulation; microbial metabolites; microbe–host reaction
(This special issue belongs to the Section Microbiology)
Viral Infections in Animals: Pathogenesis and Immunity
edited by
submission deadline 1 Sep 2026 | 1 articles | Viewed by 3555 | Submission Open
Keywords: virus–host interactions; antiviral immunity; mechanisms of viral pathogenesis
(This special issue belongs to the Section Immunology)
Latest Discoveries in Non-Model Organisms and Non-Translational Biology submission deadline 8 Sep 2026 | Viewed by 548 | Submission Open
Keywords: basic biological research; non-translational biology; non-clinical biology; fundamental science; non-model organisms; model organisms; scientific curiosity–driven research; biological diversity; experimental biology; theoretical biology
Feature Papers on Developmental and Reproductive Biology
edited by
submission deadline 15 Sep 2026 | 18 articles | Viewed by 54077 | Submission Open
Keywords: embryo/fetus development; reproductive biology; gametogenesis; differentiation; growth; homeostasis; regeneration; aging; cell cycle regulation; stem cells; organoids
(This special issue belongs to the Section Developmental and Reproductive Biology)
Molecular and Cellular Mechanisms of Neuroinflammation and Chronic Pain
edited by Mario Garcia-Dominguez
submission deadline 15 Sep 2026 | 1 articles | Viewed by 821 | Submission Open
Keywords: neuroinflammation; chronic pain; neuroimmune interactions; glial activation; cytokine signaling; synaptic plasticity; oxidative stress; epigenetic regulation; microglia and astrocytes; therapeutic targets
(This special issue belongs to the Section Neuroscience)
Signalling Pathways in Cancer and Disease submission deadline 30 Sep 2026 | 7 articles | Viewed by 14097 | Submission Open
Keywords: cancer; signalling; metastasis; tumorigenesis; cancer targeting
(This special issue belongs to the Section Cancer Biology)
Plant Breeding: From Biology to Biotechnology
edited by Juwu Gong
submission deadline 30 Sep 2026 | 8 articles | Viewed by 14084 | Submission Open
Keywords: plant breeding; biotechnology; molecular marker-assisted selection; genetic engineering; genome editing; tissue culture; phenotype; genetics; omics
(This special issue belongs to the Section Biotechnology)
Research Advancements in Oral Biology
edited by and Nina Petrović
submission deadline 30 Sep 2026 | 5 articles | Viewed by 13420 | Submission Open
Keywords: oral biology; oral tissue regeneration; artificial intelligence (AI) in dentistry; genomics and proteomics in dentistry; dental research; salivary diagnostics
(This special issue belongs to the Section Medical Biology)
Large Animal Experimental and Epidemiological Models for Diseases submission deadline 30 Sep 2026 | 5 articles | Viewed by 10405 | Submission Open
Keywords: large animal model; dog; pig; ruminants; experimental study; epidemiological study; infectious diseases; non-infectious diseases; treatment; disease control; disease prediction
(This special issue belongs to the Section Medical Biology)
Experimental Biology, Life Science and One Health: From Basic to Translational Research
edited by
submission deadline 30 Sep 2026 | 5 articles | Viewed by 7257 | Submission Open
Keywords: anatomy, histology, embryology; aquatic environment and ecosystem; biotechnology and bioengineering; cell stress; environment and health; extracellular vesicles; fight against cancer; movement and nutrition science; neuroscience; plant ecology and ecosystem; regenerative biomedicine
Advances in Animal Functional Genomics
edited by Chugang Mei
submission deadline 30 Sep 2026 | 4 articles | Viewed by 4838 | Submission Open
Keywords: functional genomics; gene editing; phenomics; epigenetics; livestock; conservation; CRISPR; host–microbiome interactions
(This special issue belongs to the Section Zoology)
Detection of Parasites and Parasitic Diseases in Animals
edited by and Agnieszka Tylkowska
submission deadline 30 Sep 2026 | 2 articles | Viewed by 3444 | Submission Open
Keywords: parasitic infections; parasitic diseases; veterinary diagnostics; molecular techniques; epidemiology; zoonoses; host-parasite interactions; antiparasitic therapies; wildlife health; preventive programs
(This special issue belongs to the Section Zoology)
The Role of Innate Immunity in Organ Transplantation
edited by Todd V. Brennan
submission deadline 30 Sep 2026 | 1 articles | Viewed by 3427 | Submission Open
Keywords: innate immunity; allograft rejection; transplantation; immune tolerance
(This special issue belongs to the Section Medical Biology)
Gut Microbiome in Health and Disease (3rd Edition)
edited by and
submission deadline 30 Sep 2026 | 2 articles | Viewed by 3213 | Submission Open
Keywords: gut microbiota; ‘gut–X’ axis; dysbiosis; food nutrition; metabolites; type 2 diabetes mellitus; gut health; immunity
(This special issue belongs to the Section Microbiology)
Genetics and Epigenetics of Neurological Disorders
edited by
submission deadline 30 Sep 2026 | 2 articles | Viewed by 2898 | Submission Open
Keywords: neurological disorders; neurogenetics; genomics; epigenomics; DNA methylation; precision medicine
(This special issue belongs to the Section Neuroscience)
The Molecular and Cellular Mechanisms of Lung Injury and Recovery
edited by Weiguo Chen, Honglong Ji and Ibra S. Fancher
submission deadline 30 Sep 2026 | 3 articles | Viewed by 2648 | Submission Open
Keywords: acute lung injury; chronic lung injury; ARDS; fibrosis; allergy; mechanisms; therapy; infection; inflammation; endothelial barrier
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Adaptation of Living Species to Environmental Stress (2nd Edition)
edited by and Sonia Del Prete
submission deadline 30 Sep 2026 | 4 articles | Viewed by 2451 | Submission Open
Keywords: adaptation; environmental stress; evolutionary response; physiological adaptation; behavioral adaptation; morphological adaptation; climate change; conservation biology; biodiversity; ecological resilience; sound waves
(This special issue belongs to the Section Ecology)
Physiology and Ecology of Animal Parasites and Related Diseases
edited by Marcela K. Castelo
submission deadline 30 Sep 2026 | 1 articles | Viewed by 1347 | Submission Open
Keywords: parasites; parasitoids; physiology; ecology; ecophysiology; diseases; global change
(This special issue belongs to the Section Zoology)
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