Special Issues

Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Leishmaniasis and Chagas Disease: Biology, Epidemiology, Treatment and Control submission deadline 15 Aug 2025 | 8 articles | Viewed by 15655 | Submission Open
Keywords: Leishmaniasis; Chagas disease; immunopathogeny; diagnosis; epidemiology; control; clinical studies; treatment; vaccine  
(This special issue belongs to the Section Microbiology)
Ferroptosis: Mechanisms and Human Disease
edited by Chan-Yen Kuo
submission deadline 15 Aug 2025 | 2 articles | Viewed by 5780 | Submission Open
Keywords: ferroptosis; systemic diseases; inflammatory response; mitochondrial-dependent redox homeostasis; microenvironment
(This special issue belongs to the Section Cell Biology)
Animal Models of Arthritis
edited by Nevena Arsenović-Ranin and Biljana Bufan
submission deadline 30 Aug 2025 | 4 articles | Viewed by 7948 | Submission Open
Keywords: animal models; rheumatoid arthritis; osteoarthritis; inflammation; immunopathology; pathological features; joints; treatment; drug screening; traditional medicine
(This special issue belongs to the Section Medical Biology)
Metabolic and Stress Responses in Aquatic Animals
edited by , Laura Fernández-Alacid and
submission deadline 31 Aug 2025 | 13 articles | Viewed by 22102 | Submission Open
Keywords: stress; metabolism; animal welfare; aquaculture; cephalopods; fish; molluscs; crustaceans; aquatic animals; animal physiology
(This special issue belongs to the Section Zoology)
The Replication Licensing System
edited by
submission deadline 31 Aug 2025 | 6 articles | Viewed by 21025 | Submission Open
Keywords: cell cycle; DNA replication; genome stability; replication licensing; MCM2-7; ORC; Cdc6; CDT1; cancer; Meier-Gorlin syndrome
(This special issue belongs to the Section Cell Biology)
Infectious Diseases: Emerging Diagnostic Methods, Updated Treatment Protocols and New Antimicrobial Agents submission deadline 31 Aug 2025 | 6 articles | Viewed by 19981 | Submission Open
Keywords: infectious diseases; pathophysiology; risk factors; prognosis; diagnostic methods; biomarkers; molecular techniques; treatment protocols; novel antibiotic
(This special issue belongs to the Section Infection Biology)
Editorial Board Members' Collection Series: “Biodiversity and Ecosystem Function under Global Change” submission deadline 31 Aug 2025 | 9 articles | Viewed by 19019 | Submission Open
Keywords: climate change; global warming; precipitation; N deposition; biological invasion; species interaction; microbial process; ecosystem function; ecosystem service
2nd Edition: Aquatic Alien Invasions and Their Impact on Biodiversity and Ecosystem Services  submission deadline 31 Aug 2025 | 8 articles | Viewed by 15558 | Submission Open
Keywords: species; aquatic invasions; biodiversity; ecosystem services; conservation
(This special issue belongs to the Section Marine Biology)
The Effect of Food- and Nutrient-Derived Molecules on Cells and Tissue submission deadline 31 Aug 2025 | 4 articles | Viewed by 13383 | Submission Open
Keywords: natural products; molecules; nutrition; antioxidants; cell biology; metabolism
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Pollination Biology
edited by
submission deadline 31 Aug 2025 | 8 articles | Viewed by 11400 | Submission Open
Keywords: conservation biology; insect diversity; pollinator-plant interactions; ecosystem service; pollinator insect
(This special issue belongs to the Section Ecology)
Editorial Board Members’ Collection Series: Pathology of Cancer and Cardiovascular Disease submission deadline 31 Aug 2025 | 2 articles | Viewed by 6615 | Submission Open
Keywords: cancer; cardiovascular disease; biomarkers; gut microbiome; inflammation; health policy; diet and lifestyle
Biology, Ecology and Management of Harmful Algae
edited by Paul V. Zimba and
submission deadline 31 Aug 2025 | 4 articles | Viewed by 6161 | Submission Open
Keywords: harmful algae; toxic algae; harmful algal bloom (HAB); excessive algae growth; microalgae and macroalgae; cyanobacteria; dinoflagellates; toxins; water quality; phytoplankton; water resources
Lipid Metabolism in Plant Growth and Development
edited by Xiaohong Yu and Yingqi Cai
submission deadline 31 Aug 2025 | 1 articles | Viewed by 3077 | Submission Open
Keywords: lipid metabolism; lipid engineering; plant growth; plant development; lipid biosynthesis; lipid signaling; lipid transport; membrane structure; energy storage; plant– microbe interactions; stress response; nutrition value; cellular process
(This special issue belongs to the Section Plant Science)
Molecular Basis of Seed Germination and Dormancy
edited by , , and Yu Cheng
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1669 | Submission Open
Keywords: molecular mechanism; genetic basis; seed germination; dormancy; genetic improvement
(This special issue belongs to the Section Plant Science)
Gene Editing and Genetic Regulation: New Insight in Insect Sex Determination, Reproductive Development and Pest Control
edited by Honglun Bi
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1277 | Submission Open
Keywords: insect gene editing; genetic regulation  ; CRISPR/Cas  ; gene drive  ; pest control; sex determination  ; reproductive development; insect sterile technique
(This special issue belongs to the Section Zoology)
Airway Smooth Muscle and Respiratory Diseases
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1133 | Submission Open
Keywords: airway; airway smooth muscle; asthma; COPD; airway hyperresponsiveness; airway inflammation; airway remodeling; bronchospasm; bronchodilators
(This special issue belongs to the Section Cell Biology)
Redox Signaling and Oxidative Stress in Health and Disease
edited by and
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1097 | Submission Open
Keywords: redox signaling; oxidative stress; antioxidant defense; cellular regulation; aging; cancer; cardiovascular diseases; neurodegenerative diseases; therapeutic approaches; digital biotechnology
(This special issue belongs to the Section Cell Biology)
Disease Biomarker Discovery and Validation
edited by Matthew James Jennings
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1047 | Submission Open
Keywords: biomarkers; prognostic validation; predictive validation; analytical validation
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Adaptation Mechanisms of Forest Trees to Abiotic Stress
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1030 | Submission Open
Keywords: genetic variation; epigenetic control; plant hormone; nitric oxide; reactive oxygen species; phenomic; metabolomic; genomic; signal transduction; gene function
(This special issue belongs to the Section Plant Science)
Regenerative Biology: Regeneration After Spinal Cord and Peripheral Nerve Injury submission deadline 31 Aug 2025 | 1 articles | Viewed by 843 | Submission Open
Keywords: neuronal regeneration; peripheral nerve repair; spinal cord injury; axonal growth; neuroplasticity; glial cells; molecular signaling pathways; stem cells in nerve regeneration; neuroinflammation; animal models of nerve injury
(This special issue belongs to the Section Neuroscience)
Cellular and Molecular Biology of Liver Diseases
edited by Matthew McMillin
submission deadline 31 Aug 2025 | Viewed by 333 | Submission Open
Keywords: drug-induced liver injury; cholestasis; hepatitis; metabolic dysfunction-associated steatotic liver disease; alcohol-associated liver disease
(This special issue belongs to the Section Cell Biology)
Microbiology and Metabolomics in Reproductive Biology submission deadline 31 Aug 2025 | Viewed by 279 | Submission Open
Keywords: maternal microbiome; metabolome; pregnancy outcomes; fetal development; biomarkers; immune function; metabolic health; disease prediction; therapeutic interventions; maternal and child health
(This special issue belongs to the Section Developmental and Reproductive Biology)
Biomarkers for Cancer Immunity
edited by Xuyao Zhang
submission deadline 31 Aug 2025 | Viewed by 279 | Submission Open
Keywords: tumor microenvironment; tumor immunity; systems immunology; resistance mechanism; biomarkers
Intermolecular Interactions in Cytochrome P450 Systems
edited by and John Hackett
submission deadline 31 Aug 2025 | Viewed by 225 | Submission Open
Keywords: cytochrome P450; NADPH-cytochrome P450 reductase; cytochrome b5; adrenodoxin; microsomes; protein– protein interactions; protein-lipid interactions; systems biochemistry of drug metabolism; cytochrome P450-dependent signaling
(This special issue belongs to the Section Biochemistry and Molecular Biology)
The Regulation of Glucose Homeostasis
edited by Aaron Aykut Uner
submission deadline 31 Aug 2025 | Viewed by 213 | Submission Open
Keywords: glucose homeostasis; brain; type 1 diabetes; type 2 diabetes; insulin sensitivity; beta-cell regeneration
(This special issue belongs to the Section Physiology)
Biological Advances in Pluripotent Stem Cells
edited by and Matthias Jung
submission deadline 31 Aug 2025 | Viewed by 179 | Submission Open
Keywords: induced pluripotent stem cell; embryonic stem cell; regenerative medicine; drug research; organoid; translational biology
(This special issue belongs to the Section Cell Biology)
Biosynthesis of Metabolites from Microorganisms, or Microorganism-Host Interaction? (Volume II) submission deadline 1 Sep 2025 | 5 articles | Viewed by 12872 | Submission Open
Keywords: biosynthesis; biological activity; biosynthesis regulation; microbial metabolites; microbe– host reaction
(This special issue belongs to the Section Microbiology)
Feature Papers on Developmental and Reproductive Biology
edited by
submission deadline 15 Sep 2025 | 6 articles | Viewed by 13265 | Submission Open
Keywords: embryo/fetus development; reproductive biology; gametogenesis; differentiation; growth; homeostasis; regeneration; aging; cell cycle regulation; stem cells; organoids
(This special issue belongs to the Section Developmental and Reproductive Biology)
Biological Rhythms and Molecular Clockworks in Physiology and Pathology submission deadline 30 Sep 2025 | 10 articles | Viewed by 29506 | Submission Open
Keywords: biological rhythms; molecular clockworks; circadian timing system; circadian desynchrony; circadian disruption; chronopathology; chronopharmacology and chronotherapeutics; chronomedicine
(This special issue belongs to the Section Physiology)
Artificial Intelligence Research for Complex Biological Systems submission deadline 30 Sep 2025 | 6 articles | Viewed by 5825 | Submission Open
Keywords: deep learning; generative artificial intelligence; bioinformatics; complex biological systems; cancer; neuroscience; next-generation sequencing; single-cell and bulk omics; genomics
(This special issue belongs to the Section Bioinformatics)
Plant Breeding: From Biology to Biotechnology
edited by Juwu Gong
submission deadline 30 Sep 2025 | 5 articles | Viewed by 5466 | Submission Open
Keywords: plant breeding; biotechnology; molecular marker-assisted selection; genetic engineering; genome editing; tissue culture; phenotype; genetics; omics
(This special issue belongs to the Section Biotechnology)
Molecular Basis of Bone Homeostasis and Skeletal Diseases
edited by
submission deadline 30 Sep 2025 | 3 articles | Viewed by 4388 | Submission Open
Keywords: osteoclast; osteoblast; bone; skeletal disease; bone formation; bone resorption; osteoporosis; osteopetrosis; human genetics; mouse genetics
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Research Advancements in Oral Biology
edited by and Nina Petrović
submission deadline 30 Sep 2025 | 1 articles | Viewed by 1675 | Submission Open
Keywords: oral biology; oral tissue regeneration; artificial intelligence (AI) in dentistry; genomics and proteomics in dentistry; dental research; salivary diagnostics
(This special issue belongs to the Section Medical Biology)
Research Progress on Melanocytes and Melanin
edited by Zeina Tannous
submission deadline 30 Sep 2025 | Viewed by 360 | Submission Open
Keywords: melanin; melanocytes; melanocyte stem cell; pigmentation; melanoma; dysplastic nevi; vitiligo; melasma
(This special issue belongs to the Section Medical Biology)
Molecular Mechanisms of Cell Signal Transduction
edited by Wenjing Zhang
submission deadline 30 Sep 2025 | Viewed by 239 | Submission Open
Keywords: molecular interactions in signaling; phosphorylation and signal propagation; post-translational modifications; cross-talk between signaling pathways; cellular response to extracellular stimuli; metabolic regulation and signaling; signaling in cancer progression; inflammatory signaling pathways; role of signaling in stem cell differentiation; innovative imaging techniques for signaling
(This special issue belongs to the Section Cell Biology)
The Role of Innate Immunity in Organ Transplantation
edited by Todd V. Brennan
submission deadline 30 Sep 2025 | Viewed by 229 | Submission Open
Keywords: innate immunity; allograft rejection; transplantation; immune tolerance
(This special issue belongs to the Section Medical Biology)
Island Ecology and Biodiversity: Managing the Effects of Climate and Land-Use Change
edited by Kealohanuiopuna Mark Kinney and Susan Cordell
submission deadline 30 Sep 2025 | Viewed by 220 | Submission Open
Keywords: island biogeography; biodiversity conservation; invasive species management; biocultural approaches; ecosystem resilience; landscape ecology; environmental sustainability; climate adaptation; social– ecological systems; restoration ecology       TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //     This page is in English   Translate to Simplified Chinese         Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh   Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com
(This special issue belongs to the Section Ecology)
Physiology and Ecology of Animal Parasites and Related Diseases
edited by Marcela K. Castelo
submission deadline 30 Sep 2025 | Viewed by 214 | Submission Open
Keywords: parasites; parasitoids; physiology; ecology; ecophysiology; diseases; global change
(This special issue belongs to the Section Zoology)
Metabolic Interactions between the Gut Microbiome and Host
edited by and
submission deadline 30 Oct 2025 | 6 articles | Viewed by 9656 | Submission Open
Keywords: gut microbiome; host; metabolome; microbial heterogeneity; biomolecules
(This special issue belongs to the Section Microbiology)
Multi-omics Approaches in Agricultural Crops to Unravel Responses to Environmental Stresses and Advance Sustainable Agriculture
edited by
submission deadline 30 Oct 2025 | 2 articles | Viewed by 2496 | Submission Open
Keywords: plant functional genomics; environmental stress; climate change; crop yield; crop quality; nutritional properties; omics approaches; genomics; transcriptomics; proteomics; metabolomics; epigenomics; phenomics; stress-tolerant crops; breeding strategies; data integration; systems biology; sustainable agriculture; underutilized crops; orphan crops; beneficial microorganisms
(This special issue belongs to the Section Plant Science)
Pathophysiology of Hearing Loss
edited by Charles E. Bishop
submission deadline 30 Oct 2025 | Viewed by 207 | Submission Open
Keywords: hearing loss; cochlea; noise; deafness genes; cell death; hair cells; inner ear; biotoxicity; metabolic risk; gene mutation; physiology and pathophysiology; animal models; biomarkers and molecular mechanisms
(This special issue belongs to the Section Physiology)
Advances in the Fields of Neurotrauma and Neuroregeneration submission deadline 31 Oct 2025 | 8 articles | Viewed by 40755 | Submission Open
Keywords: neurotrauma; spinal cord injury; traumatic brain injury; neuropathic pain; neuroinflammation; axonal regeneration; postinjury plasticity; neurorehabilitation; cell transplantation
(This special issue belongs to the Section Neuroscience)
Young Researchers in Neuroscience
edited by Yansheng Du
submission deadline 31 Oct 2025 | 2 articles | Viewed by 15498 | Submission Open
Keywords: neurobiology; cell biology; molecular mechanisms; neural development; synaptic function; ion channels; neurotransmitter systems; gene expression; neuronal signaling; cellular physiology
(This special issue belongs to the Section Neuroscience)
Immunosenescence and Its Modification by Interventions
edited by and Luca Pangrazzi
submission deadline 31 Oct 2025 | 1 articles | Viewed by 3962 | Submission Open
Keywords: immunosenescence; aging immune system; inflammaging; vaccine efficacy in elderly; nutritional immunomodulation; exercise and immunity; senolytic therapies; T-cell exhaustion; thymic rejuvenation; age-related diseases
(This special issue belongs to the Section Immunology)
Progress in Wildlife Conservation, Management and Biological Research
edited by Ana Carolina Srbek-Araujo
submission deadline 31 Oct 2025 | 4 articles | Viewed by 2843 | Submission Open
Keywords: adaptive capacity; climate change; conservation opportunities; species vulnerability; threatened species; wildlife conservation; wildlife management
(This special issue belongs to the Section Conservation Biology and Biodiversity)
Pathogen-Host Interaction and Vaccine/Drug Design
edited by Iga Kucharska
submission deadline 31 Oct 2025 | 1 articles | Viewed by 2332 | Submission Open
Keywords: infectious diseases; host– pathogen interactions; vaccine; drug design; immune evasion; immunogen
(This special issue belongs to the Section Medical Biology)
Advances in Omics Approaches for Understanding Metabolic Disorders: Environmental and Nutritional Perspectives
edited by Yue Ge
submission deadline 31 Oct 2025 | 1 articles | Viewed by 972 | Submission Open
Keywords: metabolic disorders; environmental exposures; nutritional factors; omics technologies; co-exposures; cumulative toxicity; metabolic pathways; human health risk assessment; advanced in vitro models; systems toxicology
(This special issue belongs to the Section Physiology)
Advancing Crop Nutritional Quality Through Genomic Approaches
edited by Gen Xu
submission deadline 31 Oct 2025 | 1 articles | Viewed by 493 | Submission Open
Keywords: crop improvement; genomics; multi-omics; genetic loci; breeding
(This special issue belongs to the Section Plant Science)
Extracellular Vesicles: Biogenesis and Functions in the Complex Landscape of Differentiation and Disease
edited by
submission deadline 31 Oct 2025 | Viewed by 441 | Submission Open
Keywords: stem cell biology; stem cell differentiation; adipogenesis; neurogenesis; extracellular vesicles in stem cell differentiation; ncRNAs; tumor microenvironment; intercellular communication
(This special issue belongs to the Section Cell Biology)
Plant-Microbe Interaction: The Cellular Mechanism Influence Plant Health
edited by and Gongjun Shi
submission deadline 31 Oct 2025 | Viewed by 342 | Submission Open
Keywords: plant-microbe interaction; plant health; plant immunity; gene-for-gene model; resistosomes; metabolic crosstalk; climate change
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