Special Issues

Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Physiological and Pathophysiological Responses to Biomaterials 2.0: From Nano- to Microscale Effects and Interactions submission deadline 31 Mar 2026 | 4 articles | Viewed by 13015 | Submission Open
Keywords: extracellular stimuli and physiological responses; plasma membrane interface; cell– material interactions; tissue– material interactions; tissue engineering; biomaterials; biomedical devices; in vitro models and on-chip/microfluidic systems; bioreactors; structure– function relationship
(This special issue belongs to the Section Physiology)
Proteomics and Human Diseases
edited by Lei Fang
submission deadline 31 Mar 2026 | 4 articles | Viewed by 10558 | Submission Open
Keywords: proteomics; clinical proteomics; human diseases; biomarker identification; therapeutic target; molecular mechanism; cancers; metabolic diseases; cardiovascular diseases; neurodegeneration diseases
(This special issue belongs to the Section Medical Biology)
How Epigenetics Shapes the Nervous System
edited by
submission deadline 31 Mar 2026 | 4 articles | Viewed by 9496 | Submission Open
Keywords: nervous system; epigenetics; DNA methylation; histone tail modifications; non-coding RNAs; neurological disorders; neurodegenerative diseases; biomarkers; environmental epigenetics
(This special issue belongs to the Section Neuroscience)
Advances in Biological Research of Chiroptera
edited by Jiang Feng, Ying Liu and
submission deadline 31 Mar 2026 | 10 articles | Viewed by 8041 | Submission Open
Keywords: individual development; ecolocation; powered flight; high-frequency hearing; pest control; bat ecosystem service; habitat suitability; evolutionary adaptations
(This special issue belongs to the Section Zoology)
Feeding Biology and Nutrition in Insects
edited by and Christopher W. Weldon
submission deadline 31 Mar 2026 | 3 articles | Viewed by 5938 | Submission Open
Keywords: diet; digestion; ecology; evolution; feeding; insects; mass-rearing; microbiome; nutrients; taste
(This special issue belongs to the Section Ecology)
The Emerging Role of Mitochondria in Neurobiology submission deadline 31 Mar 2026 | 1 articles | Viewed by 5647 | Submission Open
Keywords: mitochondrial dynamics; neurodegenerative diseases; neuronal bioenergetics; synaptic function; neurogenesis; neuronal plasticity
(This special issue belongs to the Section Neuroscience)
Pathophysiology of Testis
edited by María Susana Theas, and María Noel Galardo
submission deadline 31 Mar 2026 | 2 articles | Viewed by 4560 | Submission Open
Keywords: testis; infertility; aging; inflammation; spermatogenesis; steroidogenesis; energy balance
(This special issue belongs to the Section Physiology)
Microbial Life at the Extremes: From Environmental Diversity to Functional Insights submission deadline 31 Mar 2026 | 3 articles | Viewed by 4252 | Submission Open
Keywords: extremophiles; microbial diversity; functional adaptation; extreme environment; synthetic extreme environments; biosignatures TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //     This page is in English   Translate to Simplified Chinese         Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh   Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com
(This special issue belongs to the Section Ecology)
Cardiovascular Autonomic Function: From Bench to Bedside—2nd Edition
edited by and
submission deadline 31 Mar 2026 | 3 articles | Viewed by 3695 | Submission Open
Keywords: dysautonomia; heart rate variability; autonomic function testing; cardiovascular autonomic function; autonomic neuroscience; syncope; orthostatic hypotension; baroreflex; autonomic molecular mechanisms
Animal Models of Gastrointestinal Diseases
edited by Yan Hu
submission deadline 31 Mar 2026 | 3 articles | Viewed by 3673 | Submission Open
Keywords: gastrointestinal diseases; animal models; digestive system; inflammatory bowel diseases; colorectal cancer; disease pathology; research methodologies; therapeutic interventions; clinical applications; translational research
(This special issue belongs to the Section Physiology)
Aquatic Animal Pathogens and Immunity
edited by and Junsoung Kwak
submission deadline 31 Mar 2026 | 2 articles | Viewed by 3008 | Submission Open
Keywords: disease mechanism; diagnosis methods for emerging diseases; host– pathogen interaction; immune defense mechanism; vaccines; immunostimulants; disease control and prevention; therapy
(This special issue belongs to the Section Microbiology)
Biological Control and Molecular Biology of Bacterial Plant Diseases
edited by Lei Li and Xiaofeng Zhou
submission deadline 31 Mar 2026 | 2 articles | Viewed by 2786 | Submission Open
Keywords: bacterial plant diseases; biological control; plant pathogens; endophytes; genomic; transcriptomic; and proteomic studies of antagonistic or pathogenic bacteria interactions; pathogenic mechanism
(This special issue belongs to the Section Plant Science)
In Vitro 2.0—Improving the Cell Culture Environment for Biology
edited by
submission deadline 31 Mar 2026 | 2 articles | Viewed by 2755 | Submission Open
Keywords: in vitro technologies; microfluids; bioreactors; organoids; tissue engineering; lab-on-a-chip; life-support systems; symbioses
(This special issue belongs to the Section Cell Biology)
Gene–Environment Interactions in Evolutionary Developmental Biology
edited by Alexander Shingleton
submission deadline 31 Mar 2026 | 1 articles | Viewed by 2731 | Submission Open
Keywords: phenotypic plasticity; gene– environment interactions; genetic architecture of plasticity; mechanisms of phenotypic variation; anthropogenic stressors; evolution of plastic responses
(This special issue belongs to the Section Evolutionary Biology)
Gene Editing and Genetic Regulation: New Insight in Insect Sex Determination, Reproductive Development and Pest Control
edited by Honglun Bi
submission deadline 31 Mar 2026 | 1 articles | Viewed by 2487 | Submission Open
Keywords: insect gene editing; genetic regulation  ; CRISPR/Cas  ; gene drive  ; pest control; sex determination  ; reproductive development; insect sterile technique
(This special issue belongs to the Section Zoology)
Integrative Immunology of the Skin: Unraveling Molecular Networks in Allergy, Autoimmunity, and Inflammation
edited by and
submission deadline 31 Mar 2026 | Viewed by 393 | Submission Open
Keywords: skin immunology; allergy and autoimmunity; chronic inflammation; cytokine and molecular networks; neuroimmune and microbiome interactions; systems immunology; multi-omics and spatial biology
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Latest Biological Advances in Neuromuscular Diseases
edited by James P. Orengo
submission deadline 31 Mar 2026 | Viewed by 321 | Submission Open
Keywords: neuromuscular medicine; muscle disease; neuropathy; neurogenetics; neurological disorders; neurodegeneration; neurology
(This special issue belongs to the Section Neuroscience)
Advances in the Molecular Evolution of Free-Living and Plant Parasitic Nematodes
edited by
submission deadline 31 Mar 2026 | Viewed by 258 | Submission Open
Keywords: biodiversity; biogeography; criptic species; phylogenetics; sequencing
(This special issue belongs to the Section Zoology)
Signaling Mechanisms Controlling Cell Fate in Cancer
edited by Wittaya Chaiwangyen and
submission deadline 31 Mar 2026 | Viewed by 216 | Submission Open
Keywords: cell fate; cancer signaling; miRNA; p53; Wnt; apoptosis; proliferation; differentiation; therapy resistance; biomarkers
(This special issue belongs to the Section Cell Biology)
Bird Biology and Conservation submission deadline 15 Apr 2026 | 15 articles | Viewed by 24989 | Submission Open
Keywords: avian conservation; ecological modeling; GIS; spatial ecology; telemetry
(This special issue belongs to the Section Conservation Biology and Biodiversity)
Mitochondria: The Signaling Organelle
edited by
submission deadline 15 Apr 2026 | 4 articles | Viewed by 8659 | Submission Open
Keywords: mitochondria; signal transduction; homeostasis; metabolism; apoptosis; redox biology; organelle communication
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Microbial Drivers of Aquatic Ecosystem Function: From Genomes to Biogeochemical Cycles
edited by and Jinjun Kan
submission deadline 15 Apr 2026 | 1 articles | Viewed by 732 | Submission Open
Keywords: aquatic microbial ecology; harmful algal blooms; nutrient cycling; trophic interactions; omics technologies; ecosystem resilience; bioremediation; population dynamics in aquatic ecosystems
(This special issue belongs to the Section Marine and Freshwater Biology)
Maternal Adaptation in Physiological and Pathological Pregnancy (2nd Edition)
edited by and
submission deadline 15 Apr 2026 | Viewed by 275 | Submission Open
Keywords: pregnancy; maternal adaptation; placenta; cardiovascular system; immune system; complications of preg-nancy; early prediction
(This special issue belongs to the Section Developmental and Reproductive Biology)
Biology, Ecology, Management and Conservation of Canidae
edited by Alberto Meriggi and
submission deadline 30 Apr 2026 | 8 articles | Viewed by 23738 | Submission Open
Keywords: Canidae; biology; ecology; management; conservation; ecosystem; habitats; niches; biodiversity; physiology; reproduction
(This special issue belongs to the Section Conservation Biology and Biodiversity)
Zoonotic Diseases submission deadline 30 Apr 2026 | 7 articles | Viewed by 10997 | Submission Open
Keywords: zoonoses; zoonotic agents; bacteria; viruses; fungi; protozoa; helminths
(This special issue belongs to the Section Infection Biology)
Machine Learning Applications in Biology—2nd Edition submission deadline 30 Apr 2026 | 4 articles | Viewed by 7346 | Submission Open
Keywords: machine learning; genomics; epigenomics; genetic variation and the environment; gene regulatory networks; integration of multipurpose NGS data
(This special issue belongs to the Section Bioinformatics)
Application of Metabolomics and Integrated Computing in Chemical Biology
edited by
submission deadline 30 Apr 2026 | 4 articles | Viewed by 7187 | Submission Open
Keywords: chemical biology; computational biology; metabolomics; computational modeling; new chemical entities (NCE); active pharmaceutical ingredients (API); characterization; metabolite profiling
Advancing Translational Science Using Bioinformatics and Big Data-Driven Approaches
edited by
submission deadline 30 Apr 2026 | 5 articles | Viewed by 6197 | Submission Open
Keywords: bioinformatics; big data analytics; artificial intelligence (AI); machine learning; deep learning; translational science; computational biology; drug repositioning; biomarker discovery; genomics; medical imaging; digital pathology; integrative analysis; disease mechanisms; functional genomics analysis; computational tool application; ethical and safety considerations; data-driven approaches
(This special issue belongs to the Section Bioinformatics)
Advances in Systems Metabolic Engineering for Biochemicals Production
edited by
submission deadline 30 Apr 2026 | 3 articles | Viewed by 5954 | Submission Open
Keywords: systems metabolic engineering; biochemicals; synthetic biology; bioprocess engineering; pathway modification; strain development
(This special issue belongs to the Section Microbiology)
Epigenetic and Genetic Control of Sperm Development and Function: From Fertility to Inheritance submission deadline 30 Apr 2026 | 1 articles | Viewed by 5234 | Submission Open
Keywords: spermatogenesis; epigenetics; sperm; male fertility; DNA methylation; histone modifications; small RNAs; epigenetic inheritance
(This special issue belongs to the Section Genetics and Genomics)
Molecular Basis of Seed Germination and Dormancy
edited by , , and Yu Cheng
submission deadline 30 Apr 2026 | 3 articles | Viewed by 5193 | Submission Open
Keywords: molecular mechanism; genetic basis; seed germination; dormancy; genetic improvement
(This special issue belongs to the Section Plant Science)
Recent Advances in Animal Anatomy submission deadline 30 Apr 2026 | 1 articles | Viewed by 3032 | Submission Open
Keywords: animal anatomy; comparative morphology; imaging anatomy; molecular anatomy; veterinary anatomy; functional morphology; evolutionary biology; wildlife conservation; developmental anatomy; anatomical adaptations
(This special issue belongs to the Section Zoology)
Germplasm Resources and Molecular Breeding for Sustainable Aquatic Species Improvement
edited by
submission deadline 30 Apr 2026 | 3 articles | Viewed by 1924 | Submission Open
Keywords: germplasm resource evaluation; molecular marker; genomics; gene editing; selective breeding; environment adaptation
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Advances in Cell and Experimental Biology: Cellular Organelle Stress and Homeostasis in Physiology and Diseases
edited by
submission deadline 30 Apr 2026 | 2 articles | Viewed by 1559 | Submission Open
Keywords: autophagy; integrated stress response; proteotoxic stress response; organelle homeostasis; ubiquitination
(This special issue belongs to the Section Cell Biology)
Population Genomics in Biodiversity Conservation in the Neotropics
edited by Rubens Pasa, Caroline Garcia and
submission deadline 30 Apr 2026 | 1 articles | Viewed by 1294 | Submission Open
Keywords: biodiversity; genomics; conservation; bioinformatics; population genomics
(This special issue belongs to the Section Conservation Biology and Biodiversity)
The Molecular Mechanisms of Chronic Inflammation Occurrence and Development
edited by Meixiu Jiang
submission deadline 30 Apr 2026 | 1 articles | Viewed by 1272 | Submission Open
Keywords: atherosclerosis; vascular calcification; neointima; macrophage; inflammation; phenotypic transformation of smooth muscle cell; endothelial dysfunction
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Natural Compounds Targeting 12 Hallmarks of Aging: A Path to Longevity Intervention submission deadline 30 Apr 2026 | Viewed by 1082 | Submission Open
Keywords: natural compounds; antiaging interventions; hallmarks of aging; telomere; epigenetics; autophagy; cellular senescence; pharmaceuticals
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Natural Compound–Drug Interactions Related to Metabolizing Enzymes and Transporters
edited by
submission deadline 30 Apr 2026 | 1 articles | Viewed by 786 | Submission Open
Keywords: drug transporters; drug-metabolizing enzymes; natural products; herb– drug interactions; food– drug interactions; nuclear receptors; kinases; expression regulation; protein targeting; functional regulation
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Research Progress in Microbial Genetics and Genomics
edited by and Udomluk Leungtongkam
submission deadline 30 Apr 2026 | 1 articles | Viewed by 565 | Submission Open
Keywords: antimicrobial resistance (AMR); microbial genetics and genomics; high-throughput DNA sequencing; comparative genomics and pan-genome; metagenomics and microbiome; mobilome; resistome and virulome; medical microbiology; environmental and food microbiology; probiotic genomics; bacteriology; mycology and virology
(This special issue belongs to the Section Microbiology)
Effects of Aquatic Sediments on Marine Ecosystems
edited by Ehui Tan and Sibo Zhang
submission deadline 30 Apr 2026 | Viewed by 533 | Submission Open
Keywords: biogeochemical cycling processes; microbial activity; sediment– water interface; benthic organisms; pollutants; global change; nutrients; environmental issues
(This special issue belongs to the Section Ecology)
Machine Learning in Pathogen Discovery
edited by
submission deadline 30 Apr 2026 | Viewed by 483 | Submission Open
Keywords: pathogen; machine learning; disease; antibiotic; virulence
(This special issue belongs to the Section Bioinformatics)
Animal Models for Disease Mechanisms (2nd Edition)
edited by
submission deadline 30 Apr 2026 | Viewed by 288 | Submission Open
Keywords: animal models; spontaneous models; induced models; disease mechanisms; pathogenesis research
(This special issue belongs to the Section Zoology)
Cutting-Edge Biomechanics: Unlocking the Future of Biomedical Engineering
edited by
submission deadline 30 Apr 2026 | Viewed by 249 | Submission Open
Keywords: computational biomechanics; experimental biomechanics; cellular and molecular biomechanics; tissue biomechanics and regenerative engineering; cardiovascular biomechanics; musculoskeletal biomechanics; sports and injury biomechanics; biomaterials and medical device innovation; medical robotics and haptics; AI and machine learning in biomechanics
(This special issue belongs to the Section Biophysics)
Advances in Cell Division and Chromosome Segregation Mechanisms
edited by
submission deadline 30 Apr 2026 | Viewed by 196 | Submission Open
Keywords: cell division; chromosome segregation; bacterial cell biology; mammalian cell cycle; genome stability; cytoskeletal dynamics; structural biology; advanced imaging
(This special issue belongs to the Section Cell Biology)
The Impact of Climate Change on Quality, Yield, and Nutritional Properties of Cereals, Legumes, and Oilseeds
edited by
submission deadline 1 May 2026 | 3 articles | Viewed by 4884 | Submission Open
Keywords: climate change; cereals; legumes; oilseeds; grain quality; seed nutrition; yield; elevated temperatures; drought; salinity; atmospheric CO2; multi-omics; field trials; crop modelling; data integration; climate resilience; breed-ing strategies; agronomic practices; beneficial microorganisms; underutilised crops; orphan crops
(This special issue belongs to the Section Plant Science)
Biological Nitrogen Removal in the Multi-Omics Era: Coupling Anammox with Microbial-Mineral Synergy
edited by Zhaoming Zheng, and
submission deadline 10 May 2026 | 1 articles | Viewed by 1274 | Submission Open
Keywords: sustainable nitrogen removal processes; anaerobic ammonium oxidation; aerobic granular sludge; microbial– mineral interactions; multi-omics microbial analysis; bioengineering in wastewater treatment; nitrogen biogeo-chemical cycle; detection and removal of emerging pollutants; water quality assurance technologies; resource re-covery from wastewater
(This special issue belongs to the Section Microbiology)
Microbial Contamination and Food Safety (Volume II)
edited by
submission deadline 15 May 2026 | 6 articles | Viewed by 22134 | Submission Open
Keywords: food contamination; food safety practices; microbial inactivation; microbial safety; microbiological hazards
(This special issue belongs to the Section Microbiology)
Internal Defense System and Evolution of Aquatic Animals
edited by
submission deadline 15 May 2026 | 9 articles | Viewed by 19088 | Submission Open
Keywords: internal defense system; evolution; aquatic animals; immunology; aquatic environment; biodiversity; pollution; ecosystems
(This special issue belongs to the Section Evolutionary Biology)
Genetic and Genomic Insights into Cardiovascular Disease
edited by Silvio Zaina and
submission deadline 15 May 2026 | Viewed by 250 | Submission Open
Keywords: coronary and carotid atheroma; lipids; thrombosis; inflammation; vascular calcification; vascular smooth muscle cells; foam cells; endothelium; immune cells; epigenetics; genetic variation; gene expression and proteomics; cell and disease models
(This special issue belongs to the Section Genetics and Genomics)
The Biology of Animal Reproduction
edited by
submission deadline 30 May 2026 | 10 articles | Viewed by 20443 | Submission Open
Keywords: the regulation of animal reproduction; follicular development and atresia; gamete and embryo development; hormonal control of reproductive processes; epigenetic regulation in reproductive biology
(This special issue belongs to the Section Developmental and Reproductive Biology)
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