Special Issues

Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Physiology and Pathophysiology of Skin
edited by Seon-Pil Jin
submission deadline 28 Feb 2026 | 10 articles | Viewed by 30727
Keywords: epidermal barrier; melanogenesis; wound healing; skin immunity; sensory perception; dermatitis; psoriasis; atopic dermatitis; autoimmune skin disorders; therapeutic approaches
(This special issue belongs to the Section Physiology)
AI Deep Learning Approach to Study Biological Questions (2nd Edition) submission deadline 28 Feb 2026 | 10 articles | Viewed by 16405
Keywords: OpenCV; Mask RCNN; YOLO; U-Net; StarDist; ImageJ; MATLAB; image segmentation; image classification; locomotion trajectory analysis; volumetric prediction; plants; animals; protozoa; invertebrates; animal behavior; developmental biology; toxicology; zebrafish; medaka; daphnia
(This special issue belongs to the Section Bioinformatics)
De Novo Detection of Transposons
edited by Dongying Gao, and
submission deadline 28 Feb 2026 | 3 articles | Viewed by 14169
Keywords: transposons; de novo detection; genome; evolution; activity; data analysis pipeline
(This special issue belongs to the Section Genetics and Genomics)
Nature's Pharmacy: Ethnobotanical Approaches to Medicinal Plant Research for the Discovery and Development of Potential Phytochemicals submission deadline 28 Feb 2026 | 6 articles | Viewed by 9897
Keywords: medicinal plants; herbal medicine; ethnopharmacology; drug discovery; bioactive compounds; biological activity; molecular mechanism; signaling pathway
(This special issue belongs to the Section Plant Science)
Bioavailability, Metabolism, and Health Effects of Phenolic Compounds
edited by and Alice Cattivelli
submission deadline 28 Feb 2026 | 3 articles | Viewed by 8655
Keywords: phenolic compounds; gut microbiota; metabolism; cardiovascular diseases; cancer; anti-proliferative activity; bioavailability; bioaccessibility
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Nutraceutical and Bioactive Compounds in Foods
edited by and
submission deadline 28 Feb 2026 | 4 articles | Viewed by 7570
Keywords: bioactive compounds; functional food ingredients; nutraceuticals; antioxidant and anti-inflammatory agents; metabolic regulation; biotechnology in food science; gut microbiota interactions   This page is in English   Translate to Simplified Chinese         Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh   Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com
(This special issue belongs to the Section Biotechnology)
Molecular Basis of Metabolic Homeostasis
edited by Verónica Miksztowicz
submission deadline 28 Feb 2026 | 3 articles | Viewed by 4133
Keywords: metabolic homeostasis; adipose tissue; liver diseases; cardiovascular disease TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //
(This special issue belongs to the Section Cell Biology)
Hope for the Forgotten: Tackling Endemic Parasitic Diseases with New Tools and Ideas
edited by Cecilia Perez Brandán
submission deadline 28 Feb 2026 | 3 articles | Viewed by 2626
Keywords: parasitic diseases; neglected tropical diseases (NTDs); host– parasite interactions; virulence mechanisms; immune evasion; molecular pathogenesis; genomic adaptations; drug discovery; drug repurposing; vaccine development; diagnostic biomarkers; tropical medicine; endemic infections
(This special issue belongs to the Section Infection Biology)
Advancements in Mesenchymal Stem Cell-Derived Secretome
edited by Chiara Giannasi
submission deadline 28 Feb 2026 | Viewed by 473
Keywords: mesenchymal stem cells; secretome; extracellular vesicles; conditioned medium; cell-free therapeutics; regeneration; immunomodulation; inflammation
(This special issue belongs to the Section Cell Biology)
Regulatory Mechanisms of Gene Expression and Its Regulatory Networks
edited by , and Ionara Rodrigues Siqueira
submission deadline 28 Feb 2026 | Viewed by 351
Keywords: transcriptional regulation; gene regulatory networks; epigenetic mechanisms; non-coding RNAs; functional genomics; multi-omics integration; signaling pathways; systems biology; epidrugs; pharmaco-transcriptomics
(This special issue belongs to the Section Genetics and Genomics)
Photomorphogenesis and Stress Response Mechanisms Involving Light in Plants
edited by Ilektra Sperdouli
submission deadline 28 Feb 2026 | Viewed by 286
Keywords: light quality and quantity; photoprotection; photoinhibition; chlorophyll; photoreceptors; abiotic stress; antioxidant defense; hormonal interactions; growth responses
(This special issue belongs to the Section Plant Science)
The Biology, Ecology, and Management of Plant Pests
edited by , , Suli Liu and Yuxin Zhou
submission deadline 1 Mar 2026 | 7 articles | Viewed by 6643 | Submission Open
Keywords: climate change; genetic diversity; life table; population dynamic; biomathematics; insect behavior; insect physiology; pest resistance; molecular mechanism; olfactory peripheral neurons; insecticide resistance; plant– pest– natural enemy; plant– insect-vector– pathogen; integrated pest management; pest monitoring and early warning
(This special issue belongs to the Section Ecology)
Physiological and Pathophysiological Responses to Biomaterials 2.0: From Nano- to Microscale Effects and Interactions submission deadline 31 Mar 2026 | 4 articles | Viewed by 12961 | Submission Open
Keywords: extracellular stimuli and physiological responses; plasma membrane interface; cell– material interactions; tissue– material interactions; tissue engineering; biomaterials; biomedical devices; in vitro models and on-chip/microfluidic systems; bioreactors; structure– function relationship
(This special issue belongs to the Section Physiology)
Proteomics and Human Diseases
edited by Lei Fang
submission deadline 31 Mar 2026 | 4 articles | Viewed by 10474 | Submission Open
Keywords: proteomics; clinical proteomics; human diseases; biomarker identification; therapeutic target; molecular mechanism; cancers; metabolic diseases; cardiovascular diseases; neurodegeneration diseases
(This special issue belongs to the Section Medical Biology)
How Epigenetics Shapes the Nervous System
edited by
submission deadline 31 Mar 2026 | 4 articles | Viewed by 9058 | Submission Open
Keywords: nervous system; epigenetics; DNA methylation; histone tail modifications; non-coding RNAs; neurological disorders; neurodegenerative diseases; biomarkers; environmental epigenetics
(This special issue belongs to the Section Neuroscience)
Advances in Biological Research of Chiroptera
edited by Jiang Feng, Ying Liu and
submission deadline 31 Mar 2026 | 8 articles | Viewed by 7631 | Submission Open
Keywords: individual development; ecolocation; powered flight; high-frequency hearing; pest control; bat ecosystem service; habitat suitability; evolutionary adaptations
(This special issue belongs to the Section Zoology)
Feeding Biology and Nutrition in Insects
edited by and Christopher W. Weldon
submission deadline 31 Mar 2026 | 3 articles | Viewed by 5851 | Submission Open
Keywords: diet; digestion; ecology; evolution; feeding; insects; mass-rearing; microbiome; nutrients; taste
(This special issue belongs to the Section Ecology)
The Emerging Role of Mitochondria in Neurobiology submission deadline 31 Mar 2026 | 1 articles | Viewed by 5598 | Submission Open
Keywords: mitochondrial dynamics; neurodegenerative diseases; neuronal bioenergetics; synaptic function; neurogenesis; neuronal plasticity
(This special issue belongs to the Section Neuroscience)
Pathophysiology of Testis
edited by María Susana Theas, and María Noel Galardo
submission deadline 31 Mar 2026 | 2 articles | Viewed by 4519 | Submission Open
Keywords: testis; infertility; aging; inflammation; spermatogenesis; steroidogenesis; energy balance
(This special issue belongs to the Section Physiology)
Microbial Life at the Extremes: From Environmental Diversity to Functional Insights submission deadline 31 Mar 2026 | 3 articles | Viewed by 4173 | Submission Open
Keywords: extremophiles; microbial diversity; functional adaptation; extreme environment; synthetic extreme environments; biosignatures TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //     This page is in English   Translate to Simplified Chinese         Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh   Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com
(This special issue belongs to the Section Ecology)
Cardiovascular Autonomic Function: From Bench to Bedside—2nd Edition
edited by and
submission deadline 31 Mar 2026 | 3 articles | Viewed by 3577 | Submission Open
Keywords: dysautonomia; heart rate variability; autonomic function testing; cardiovascular autonomic function; autonomic neuroscience; syncope; orthostatic hypotension; baroreflex; autonomic molecular mechanisms
Animal Models of Gastrointestinal Diseases
edited by Yan Hu
submission deadline 31 Mar 2026 | 3 articles | Viewed by 3559 | Submission Open
Keywords: gastrointestinal diseases; animal models; digestive system; inflammatory bowel diseases; colorectal cancer; disease pathology; research methodologies; therapeutic interventions; clinical applications; translational research
(This special issue belongs to the Section Physiology)
Aquatic Animal Pathogens and Immunity
edited by and Junsoung Kwak
submission deadline 31 Mar 2026 | 2 articles | Viewed by 2873 | Submission Open
Keywords: disease mechanism; diagnosis methods for emerging diseases; host– pathogen interaction; immune defense mechanism; vaccines; immunostimulants; disease control and prevention; therapy
(This special issue belongs to the Section Microbiology)
Biological Control and Molecular Biology of Bacterial Plant Diseases
edited by Lei Li and Xiaofeng Zhou
submission deadline 31 Mar 2026 | 2 articles | Viewed by 2700 | Submission Open
Keywords: bacterial plant diseases; biological control; plant pathogens; endophytes; genomic; transcriptomic; and proteomic studies of antagonistic or pathogenic bacteria interactions; pathogenic mechanism
(This special issue belongs to the Section Plant Science)
In Vitro 2.0—Improving the Cell Culture Environment for Biology
edited by
submission deadline 31 Mar 2026 | 2 articles | Viewed by 2671 | Submission Open
Keywords: in vitro technologies; microfluids; bioreactors; organoids; tissue engineering; lab-on-a-chip; life-support systems; symbioses
(This special issue belongs to the Section Cell Biology)
Gene–Environment Interactions in Evolutionary Developmental Biology
edited by Alexander Shingleton
submission deadline 31 Mar 2026 | 1 articles | Viewed by 2647 | Submission Open
Keywords: phenotypic plasticity; gene– environment interactions; genetic architecture of plasticity; mechanisms of phenotypic variation; anthropogenic stressors; evolution of plastic responses
(This special issue belongs to the Section Evolutionary Biology)
Gene Editing and Genetic Regulation: New Insight in Insect Sex Determination, Reproductive Development and Pest Control
edited by Honglun Bi
submission deadline 31 Mar 2026 | 1 articles | Viewed by 2390 | Submission Open
Keywords: insect gene editing; genetic regulation  ; CRISPR/Cas  ; gene drive  ; pest control; sex determination  ; reproductive development; insect sterile technique
(This special issue belongs to the Section Zoology)
Molecular Insights into the Immune Contexture of Tumors
edited by and Guilherme Zweig Rocha
submission deadline 31 Mar 2026 | 1 articles | Viewed by 606 | Submission Open
Keywords: immunology; immune oncology; cancer; molecular biology; biomarkers; inflammation
(This special issue belongs to the Section Cancer Biology)
Integrative Immunology of the Skin: Unraveling Molecular Networks in Allergy, Autoimmunity, and Inflammation
edited by and
submission deadline 31 Mar 2026 | Viewed by 379 | Submission Open
Keywords: skin immunology; allergy and autoimmunity; chronic inflammation; cytokine and molecular networks; neuroimmune and microbiome interactions; systems immunology; multi-omics and spatial biology
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Latest Biological Advances in Neuromuscular Diseases
edited by James P. Orengo
submission deadline 31 Mar 2026 | Viewed by 316 | Submission Open
Keywords: neuromuscular medicine; muscle disease; neuropathy; neurogenetics; neurological disorders; neurodegeneration; neurology
(This special issue belongs to the Section Neuroscience)
Advances in the Molecular Evolution of Free-Living and Plant Parasitic Nematodes
edited by
submission deadline 31 Mar 2026 | Viewed by 250 | Submission Open
Keywords: biodiversity; biogeography; criptic species; phylogenetics; sequencing
(This special issue belongs to the Section Zoology)
Signaling Mechanisms Controlling Cell Fate in Cancer
edited by Wittaya Chaiwangyen and
submission deadline 31 Mar 2026 | Viewed by 206 | Submission Open
Keywords: cell fate; cancer signaling; miRNA; p53; Wnt; apoptosis; proliferation; differentiation; therapy resistance; biomarkers
(This special issue belongs to the Section Cell Biology)
Bird Biology and Conservation submission deadline 15 Apr 2026 | 15 articles | Viewed by 24560 | Submission Open
Keywords: avian conservation; ecological modeling; GIS; spatial ecology; telemetry
(This special issue belongs to the Section Conservation Biology and Biodiversity)
Mitochondria: The Signaling Organelle
edited by
submission deadline 15 Apr 2026 | 4 articles | Viewed by 8423 | Submission Open
Keywords: mitochondria; signal transduction; homeostasis; metabolism; apoptosis; redox biology; organelle communication
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Microbial Drivers of Aquatic Ecosystem Function: From Genomes to Biogeochemical Cycles
edited by and Jinjun Kan
submission deadline 15 Apr 2026 | 1 articles | Viewed by 713 | Submission Open
Keywords: aquatic microbial ecology; harmful algal blooms; nutrient cycling; trophic interactions; omics technologies; ecosystem resilience; bioremediation; population dynamics in aquatic ecosystems
(This special issue belongs to the Section Marine and Freshwater Biology)
Maternal Adaptation in Physiological and Pathological Pregnancy (2nd Edition)
edited by and
submission deadline 15 Apr 2026 | Viewed by 270 | Submission Open
Keywords: pregnancy; maternal adaptation; placenta; cardiovascular system; immune system; complications of preg-nancy; early prediction
(This special issue belongs to the Section Developmental and Reproductive Biology)
Biology, Ecology, Management and Conservation of Canidae
edited by Alberto Meriggi and
submission deadline 30 Apr 2026 | 8 articles | Viewed by 23457 | Submission Open
Keywords: Canidae; biology; ecology; management; conservation; ecosystem; habitats; niches; biodiversity; physiology; reproduction
(This special issue belongs to the Section Conservation Biology and Biodiversity)
Zoonotic Diseases submission deadline 30 Apr 2026 | 7 articles | Viewed by 10852 | Submission Open
Keywords: zoonoses; zoonotic agents; bacteria; viruses; fungi; protozoa; helminths
(This special issue belongs to the Section Infection Biology)
Machine Learning Applications in Biology—2nd Edition submission deadline 30 Apr 2026 | 4 articles | Viewed by 7192 | Submission Open
Keywords: machine learning; genomics; epigenomics; genetic variation and the environment; gene regulatory networks; integration of multipurpose NGS data
(This special issue belongs to the Section Bioinformatics)
Application of Metabolomics and Integrated Computing in Chemical Biology
edited by
submission deadline 30 Apr 2026 | 4 articles | Viewed by 7095 | Submission Open
Keywords: chemical biology; computational biology; metabolomics; computational modeling; new chemical entities (NCE); active pharmaceutical ingredients (API); characterization; metabolite profiling
Advancing Translational Science Using Bioinformatics and Big Data-Driven Approaches
edited by
submission deadline 30 Apr 2026 | 5 articles | Viewed by 6015 | Submission Open
Keywords: bioinformatics; big data analytics; artificial intelligence (AI); machine learning; deep learning; translational science; computational biology; drug repositioning; biomarker discovery; genomics; medical imaging; digital pathology; integrative analysis; disease mechanisms; functional genomics analysis; computational tool application; ethical and safety considerations; data-driven approaches
(This special issue belongs to the Section Bioinformatics)
Advances in Systems Metabolic Engineering for Biochemicals Production
edited by
submission deadline 30 Apr 2026 | 3 articles | Viewed by 5827 | Submission Open
Keywords: systems metabolic engineering; biochemicals; synthetic biology; bioprocess engineering; pathway modification; strain development
(This special issue belongs to the Section Microbiology)
Epigenetic and Genetic Control of Sperm Development and Function: From Fertility to Inheritance submission deadline 30 Apr 2026 | 1 articles | Viewed by 5105 | Submission Open
Keywords: spermatogenesis; epigenetics; sperm; male fertility; DNA methylation; histone modifications; small RNAs; epigenetic inheritance
(This special issue belongs to the Section Genetics and Genomics)
Molecular Basis of Seed Germination and Dormancy
edited by , , and Yu Cheng
submission deadline 30 Apr 2026 | 3 articles | Viewed by 5070 | Submission Open
Keywords: molecular mechanism; genetic basis; seed germination; dormancy; genetic improvement
(This special issue belongs to the Section Plant Science)
Recent Advances in Animal Anatomy submission deadline 30 Apr 2026 | 1 articles | Viewed by 2995 | Submission Open
Keywords: animal anatomy; comparative morphology; imaging anatomy; molecular anatomy; veterinary anatomy; functional morphology; evolutionary biology; wildlife conservation; developmental anatomy; anatomical adaptations
(This special issue belongs to the Section Zoology)
Germplasm Resources and Molecular Breeding for Sustainable Aquatic Species Improvement
edited by
submission deadline 30 Apr 2026 | 3 articles | Viewed by 1874 | Submission Open
Keywords: germplasm resource evaluation; molecular marker; genomics; gene editing; selective breeding; environment adaptation
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Advances in Cell and Experimental Biology: Cellular Organelle Stress and Homeostasis in Physiology and Diseases
edited by
submission deadline 30 Apr 2026 | 2 articles | Viewed by 1505 | Submission Open
Keywords: autophagy; integrated stress response; proteotoxic stress response; organelle homeostasis; ubiquitination
(This special issue belongs to the Section Cell Biology)
Population Genomics in Biodiversity Conservation in the Neotropics
edited by Rubens Pasa, Caroline Garcia and
submission deadline 30 Apr 2026 | 1 articles | Viewed by 1242 | Submission Open
Keywords: biodiversity; genomics; conservation; bioinformatics; population genomics
(This special issue belongs to the Section Conservation Biology and Biodiversity)
The Molecular Mechanisms of Chronic Inflammation Occurrence and Development
edited by Meixiu Jiang
submission deadline 30 Apr 2026 | 1 articles | Viewed by 1241 | Submission Open
Keywords: atherosclerosis; vascular calcification; neointima; macrophage; inflammation; phenotypic transformation of smooth muscle cell; endothelial dysfunction
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Natural Compounds Targeting 12 Hallmarks of Aging: A Path to Longevity Intervention submission deadline 30 Apr 2026 | Viewed by 1072 | Submission Open
Keywords: natural compounds; antiaging interventions; hallmarks of aging; telomere; epigenetics; autophagy; cellular senescence; pharmaceuticals
(This special issue belongs to the Section Biochemistry and Molecular Biology)
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