2026 September-2 - 107 articles
Understanding habitat selection is essential for predicting species distributions and developing effective conservation strategies, particularly for semi-aquatic mammals. However, habitat requirements of the Eurasian water shrew (Neomys fodiens, EWS)...
Genome-wide association studies (GWASs) have become a central tool in plant genomics, providing high-resolution access to the genetic architecture of complex traits in cereal crops. This review observes the application of GWASs to biotic and abiotic...
The intestinal barrier (IB) is a critical interface that maintains internal homeostasis. Its functional compromise—termed intestinal hyperpermeability—permits luminal antigens such as lipopolysaccharide to enter the circulation, triggerin...
Fluoxetine, a selective serotonin reuptake inhibitor (SSRI), is one of the most detected antidepressants in wastewater, managing to enter watersheds where it is taken up by freshwater fauna. Here we asked if the serotonergic system affects the locomo...
GABAergic neurotransmission plays a central role in regulating the mammalian circadian clock. However, the precise contribution of GABA type A receptor (GABAAR) subunits to timekeeping within the suprachiasmatic nucleus (SCN) remains incompletely def...
Optogenetic manipulation is pivotal in basic neuroscience research and in studying neuropsychiatric disorders, enabling the activation or inhibition of neuronal populations with millisecond precision. However, this technique can induce artificial neu...
Inflammatory cytokines are well-established drivers of organ-specific pathology, yet their seasonal patterning remains poorly integrated into a single explanatory framework. This review examines whether classical descriptions of Bi syndrome in the Ye...
The genus Triplophysa (Nemacheilidae), a dominant component of the Qinghai–Tibet Plateau (QTP) fish fauna, remains poorly understood in its evolutionary relationships and phylogeography. We integrated mitochondrial phylogenomics and population...
Rv3787c is a putative S-adenosylmethionine (SAM)-dependent methyltransferase from Mycobacterium tuberculosis, the main agent of human tuberculosis. Researchers identified a conserved non-synonymous polymorphism within the highly transmissible Latin A...
Amazonian bufonid toads represent an important source of bioactive compounds with promising pharmacological potential. Among them, Rhaebo guttatus and Rhinella marina produce complex cutaneous and parotoid gland secretions composed mainly of bufadien...
In peach production, the chilling requirement (CR) of cultivars has emerged as one of the most important limiting factors. DNA methylation plays an important role in regulating plant growth and development, environmental adaptation, and phenotypic es...
Altitude and soil depth were associated with vegetation, soil properties, and microbial communities in alpine ecosystems, yet a comprehensive understanding of how these gradients shape soil microbial and physicochemical characteristics on the Qinghai...
Bacterial wilt, caused by Ralstonia solanacearum, is a devastating soilborne disease often referred to as plant cancer. It threatens hundreds of species of plants and causes losses in yield and a deterioration in the quality of infected plants. Delay...
Hypoxia poses a significant threat to hippocampal neurons, but the temporal dynamics of mitophagy pathways in neuronal models remain incompletely characterized. This study aims to delineate time-dependent mitochondrial structural damage, fragmentatio...
FK506-binding protein 4 (FKBP4), also known as FKBP52, is an HSP90 co-chaperone associated with poor outcomes in lung adenocarcinoma (LUAD). We evaluated FKBP4 using TCGA-LUAD, cBioPortal, CellMiner, and H1299 cell data. Among 535 primary tumors, the...
Nearshore artificial facilities greatly alter coastal flow fields and habitats. As typical underwater artificial structures, offshore wind turbine pile foundations have unclear mechanisms for influencing fish habitats. Given the high similarity of fl...
Phosphorus (P) leaching from dryland from purple soils poses a significant risk to water quality, yet effective mitigation strategies and their underlying microbial mechanisms remain poorly understood. This study aimed to evaluate the efficacy of bio...
PU.1 is a hematopoietic ETS-family transcription factor that serves as a master regulator of immune cell development, lineage commitment, chromatin organization, and innate immune function. PU.1 is essential for the generation and maintenance of mono...
Populus simonii × P. nigra is a valuable model for studying woody plant responses to saline-alkaline stress, however the molecular mechanisms underlying its adaptation remain poorly understood. Here, integrated transcriptomic and metabolomic an...
Potato tubers exhibit prominent spatial heterogeneity in starch accumulation across distinct anatomical zones, yet the underlying transcriptional and metabolic regulatory mechanisms remain unclear, especially the molecular basis for divergent starch...
Cochliomyia hominivorax, the main etiological agent of traumatic myiasis in the New World, continues to have significant health and economic impacts due to its effects on animal health, livestock production and public health in affected regions. Alth...
A sequential two-stage chemo-biocatalytic process was investigated for the conversion of D-xylose to furfuryl alcohol (FOL), an important furan derivative widely used in the manufacture of resins, polymers, fuels, and other value-added products. In t...
Arsenic (As) pollution poses serious threats to soil ecosystems and plant growth. Arbuscular mycorrhizal fungi (AMF) have been confirmed to enhance As tolerance in host plants, making mycorrhizal-assisted phytoremediation a promising and practical st...
The date palm mite Oligonychus afrasiaticus is one of the most destructive phytophagous pests in date palm orchards and can cause severe economic losses when not effectively managed. Although chemical acaricides remain the primary control method, the...
Hemodynamic shear stress is a critical mechanical determinant of endothelial homeostasis, yet the mechanosensitive pathways governing metabolic reprogramming remain incompletely understood. Apolipoprotein A-I binding protein (AIBP) regulates choleste...
Climate change can alter the potential distribution patterns of species, and the responses of medicinal plants to environmental change are directly relevant to resource conservation and the planning of suitable cultivation regions. Using the MaxEnt m...
Herpes simplex encephalitis (HSE), predominantly caused by herpes simplex virus type 1 (HSV-1), is the most common sporadic viral encephalitis worldwide and remains life threatening despite antiviral therapy. Although herpes simplex virus (HSV) infec...
Wildlife monitoring and environmental microbiome profiling provide complementary perspectives for assessing habitats of protected aquatic species. This study integrated long-term computer vision monitoring, 16S rRNA amplicon sequencing, and water-qua...
Salinity, temperature and body weight dominate seawater acclimation in rainbow trout (Oncorhynchus mykiss), yet few studies simultaneously explore their main effects and potential correlative interactive patterns in hepatic responses. A 60-day L9 (33...
Breast cancer remains a significant cause of cancer-related mortality in Africa, where late-stage diagnosis, limited access to specialised care, and underrepresentation in biomedical research continue to impede improvements in patient outcomes. At th...
Antioxidants protect cells from oxidative damage through mechanisms such as radical scavenging, metal chelation, and maintenance of redox homeostasis. Yeasts are useful hosts for antioxidant production. This review distinguishes native yeast metaboli...
The genus Ityogonimus currently comprises three recognized species: Ityogonimus ocreatus, Ityogonimus lorum, and Ityogonimus scalopi. The type species of this genus, I. ocreatus, parasitizes European moles. Despite the widespread distribution of the...
The physiological effects of glucagon-like peptide-1 receptor agonists (GLP-1RAs) and dual glucose-dependent insulinotropic polypeptide (GIP)/GLP-1RAs extend beyond glucose metabolism and body weight regulation. Accumulating clinical evidence has hig...
Over-representation analysis (ORA) is widely used to interpret selected-gene lists, including differentially expressed genes and cell-type marker genes. Unlike ranked-list gene-set enrichment analysis (GSEA), ORA tests whether selected genes are over...
Influenza viruses undergo continuous genetic and antigenic evolution, making sustained surveillance essential for monitoring changes in virus circulation and vaccine relevance. We analyzed influenza epidemiology and viral evolution in Kazakhstan acro...
Leaf rust severely limits the yield and quality of Zanthoxylum armatum (Z. armatum). This study compared a rust-susceptible line (S-YF) and a naturally bud-sport-derived resistant line (R-YF) originating from the same mother plant, using physiologica...
Over the past few years, considerable scholarly interest has been directed toward the synergistic application of natural compounds alongside conventional antibiotics to address infections stemming from multidrug-resistant (MDR) pathogens. The primary...
Opuntia stricta is a highly invasive cactus species that threatens arid and semiarid ecosystems worldwide. We identified the optimal species distribution model (SDM) to predict its global habitat suitability using three hierarchical frameworks: clima...
Water-soluble vitamins participate in essential metabolic, redox, and coenzyme-dependent processes, yet their effective delivery can be limited by chemical instability, degradation during processing or storage, restricted membrane transport, and form...
Alternative feed ingredients may alter intestinal structure and function. We examined jejunal, ileal, and cecal responses in Large Diqing Tibetan pigs fed a control diet or one in which walnut cake replaced 50% of soybean meal. Two pigs were sampled...
Early sowing is one of the most promising strategies for mitigating the adverse effects of climate change on maize production in temperate regions. A rapid and strong initial response is critical for seedling survival and can indicate early-sowing to...
Cells are continuously exposed to mechanical stimuli arising from the extracellular matrix, neighboring cells, and tissue architecture. Through mechanotransduction, these physical cues are converted into intracellular signaling events that regulate c...
In recent decades, plant sciences have profoundly transformed our philosophical understanding of plants, moving beyond the traditional view of the plant organism as a passive, mechanical entity devoid of agency. Contemporary research into plant physi...
Grain fat content contributes to nutritional quality in foxtail millet, but its genetic basis remains incompletely understood. We evaluated a 256-line recombinant inbred population derived from Jingu21 and Chuang29 in two environments. Among the indi...
In mammalian systems, translational responses to amino acid limitation are commonly framed as mechanistic target of rapamycin complex 1 (mTORC1) inhibition and activation of the general control nonderepressible 2 (GCN2)–eukaryotic initiation fa...
This study aimed to characterize the genomic diversity, population structure, and candidate regions consistent with selection in Hamdani (HAM) sheep using high-density SNP generated by double-digest restriction site-associated DNA sequencing (ddRADse...
Photorespiration links carbon metabolism with nitrogen assimilation in C3 plants, but its relationship with nitrogen productivity in perennial turfgrass remains unclear. Ten Kentucky bluegrass (Poa pratensis L.) cultivars were screened for photorespi...
Macadamia is a diploid rainforest tree native to Australia. A total of 349 samples, including wild and domesticated accessions, were subjected to whole-genome sequencing, identifying 4.2 to 7.7 million, 2.4 to 7.4 million, 2.8 to 4.4 million, 1.6 to...
As a typical turbid-water reef coral, Turbinaria peltata shows strong tolerance to high temperature and sediment disturbance, yet its basin-scale niche drivers and glacial distribution dynamics across the Indo-West Pacific remain unclear. Here we con...
Soy products are among the most common sources of protein, and large volumes of wastewater are produced from legume processing. In this study, the Priestia aryabhattai FM5 strain, isolated from soil, was found to be capable of nitrogen assimilation....
of 3
