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  • Review
  • Open Access
49 Citations
9,025 Views
41 Pages

Advances in Organic Materials for Next-Generation Optoelectronics: Potential and Challenges

  • Ghazi Aman Nowsherwan,
  • Qasim Ali,
  • Umar Farooq Ali,
  • Muhammad Ahmad,
  • Mohsin Khan and
  • Syed Sajjad Hussain

11 November 2024

This review provides a comprehensive overview of recent advancements in the synthesis, properties, and applications of organic materials in the optoelectronics sector. The study emphasizes the critical role of organic materials in the development of...

  • Review
  • Open Access
27 Citations
23,848 Views
34 Pages

Aldehydes: What We Should Know About Them

  • Alessia Catalano,
  • Annaluisa Mariconda,
  • Assunta D’Amato,
  • Domenico Iacopetta,
  • Jessica Ceramella,
  • Maria Marra,
  • Carmela Saturnino,
  • Maria Stefania Sinicropi and
  • Pasquale Longo

21 October 2024

From Egyptian mummies to the Chanel N° 5 perfume, aldehydes have been used for a long time and continue to impact our senses in a wide range of perfumes, foods, and beverages. Aldehydes represent one of the categories of volatile organic compound...

  • Review
  • Open Access
22 Citations
24,421 Views
48 Pages

A Review on Barbituric Acid and Its Derivatives: Synthesis, Reactions, and Bio-Applications

  • Navneet Kaur,
  • Manvinder Kaur,
  • Harvinder Singh Sohal,
  • Haesook Han and
  • Pradip K. Bhowmik

5 September 2024

Barbituric acid is a heterocyclic compound with various pharmacological and biological applications. This review paper provides a comprehensive overview of barbituric acid’s synthesis, reactions, and bio-applications, highlighting its multiface...

  • Review
  • Open Access
20 Citations
10,951 Views
22 Pages

Recent Developments Towards the Synthesis of Triazole Derivatives: A Review

  • Issam Ameziane El Hassani,
  • Khouloud Rouzi,
  • Anouar Ameziane El Hassani,
  • Khalid Karrouchi and
  • M’hammed Ansar

24 October 2024

The triazole scaffold is a crucial component of heterocyclic chemistry, serving as a basic building block in organic synthesis, materials science, and medicinal chemistry. Triazole is a five-membered ring composed of three nitrogen atoms and two carb...

  • Review
  • Open Access
15 Citations
5,390 Views
18 Pages

Environmental Fate, Ecotoxicity, and Remediation of Heterocyclic Pharmaceuticals as Emerging Contaminants: A Review of Long-Term Risks and Impacts

  • Oussama Baaloudj,
  • Laura Scrano,
  • Sabino Aurelio Bufo,
  • Lee-Ann Sade Modley,
  • Filomena Lelario,
  • Angelica Rebecca Zizzamia,
  • Lucia Emanuele and
  • Monica Brienza

2 January 2025

Heterocyclic pharmaceuticals are emerging contaminants due to their toxic, carcinogenic nature and detrimental impact on the natural ecosystem. These compounds pose a significant environmental concern given their widespread use in medical therapy, co...

  • Review
  • Open Access
14 Citations
5,077 Views
13 Pages

20 August 2024

The art of dyeing textiles has a long history, as natural dyes have been used since prehistoric times. With the development of synthetic dyes in the 19th century, the focus shifted from natural to synthetic dyes due to their superior properties. Rece...

  • Review
  • Open Access
13 Citations
4,912 Views
21 Pages

9 November 2023

Mannich bases are a class of organic compounds usually obtained by the condensation reaction between an amine, a compound with active hydrogens, and an aldehyde. They are versatile intermediates in organic synthesis, and those compounds containing th...

  • Review
  • Open Access
12 Citations
5,500 Views
19 Pages

17 May 2023

Organic molecules are gaining special attention over the last years in the corrosion area thanks to their general low achievable cytotoxicity, structural versatility, and environmentally friendly obtainment methods. Under those approaches, synthetic...

  • Review
  • Open Access
11 Citations
12,033 Views
49 Pages

An Overview of Quinolones as Potential Drugs: Synthesis, Reactivity and Biological Activities

  • Ayoub El-mrabet,
  • Amal Haoudi,
  • Youssef Kandri-Rodi and
  • Ahmed Mazzah

3 April 2025

Quinolones represent one of the largest classes of synthetic antibiotics used in both human and veterinary medicine. Since the discovery of nalidixic acid, a substantial body of research has been carried out on quinolones, resulting in the synthesis...

  • Review
  • Open Access
11 Citations
5,295 Views
49 Pages

6 June 2024

Three decades after A. P. de Silva’s seminal paper introduced the concept of logic gates at the molecular level, the field of molecular logic gates (MLGs) has witnessed significant advancements. MLGs are devices designed to perform logical oper...

  • Review
  • Open Access
10 Citations
4,134 Views
13 Pages

19 April 2023

Sulfoxides and sulfinamides play important roles in the pharmaceutical industry, organic synthesis and fine chemicals. This review will demonstrate that, under catalysis by transition metals, β-sulfinyl esters, as nucleophilic reagents, react wi...

  • Review
  • Open Access
10 Citations
7,826 Views
23 Pages

5 December 2024

Pyrazole and tetrazole are among the most important heterocyclic members of the azole family. Over the past decade, these N-heterocycles and their derivatives have demonstrated specific properties that give them potent applications in several fields...

  • Review
  • Open Access
10 Citations
4,530 Views
30 Pages

Conducting Polymers in Solar Cells: Insights, Innovations, and Challenges

  • Aliya Yelshibay,
  • Sherif Dei Bukari,
  • Bakhytzhan Baptayev and
  • Mannix P. Balanay

20 December 2024

The pursuit of sustainable energy sources has led to significant advances in solar cell technology, with conducting polymers (CPs) emerging as key innovations. This review examines how CPs improve the performance and versatility of three important ty...

  • Review
  • Open Access
8 Citations
5,709 Views
16 Pages

14 January 2025

Heterocyclic compounds are the cornerstone for active pharmaceutical ingredients. Among heterocycles, isoindoline core occupies a special place, as ten commercial bioactive compounds/drugs contain this skeleton decorated with several functional group...

  • Review
  • Open Access
8 Citations
4,880 Views
31 Pages

Indole-Based Macrocyclization by Metal-Catalyzed Approaches

  • Subba Rao Cheekatla,
  • Debashis Barik,
  • Geethanjali Anand,
  • Rakhi Mol K. M. and
  • Mintu Porel

4 July 2023

This review is dedicated to the different varieties of macrocycles synthesis bearing indole units in their architecture by metal-catalyzed strategies. The progress of the new macrocyclization approaches is persisted be a keen area of research. Macroc...

  • Review
  • Open Access
6 Citations
4,507 Views
15 Pages

28 November 2023

The modern trend in sunscreen products is towards the development of UV filters with multi-functional properties, to provide a broad shielding against ultraviolet radiation, antioxidant activity, and the prevention of skin cancer. Additionally, they...

  • Article
  • Open Access
6 Citations
3,700 Views
14 Pages

5 July 2024

Bridgehead alkenes are polycyclic molecules bearing at least one C=C bond that includes a bridgehead carbon atom. For small bicyclic systems, these bonds are highly strained due to geometric constraints placed on the sp2 hybridized carbon atoms. Thes...

  • Review
  • Open Access
6 Citations
2,965 Views
14 Pages

21 October 2024

Photodynamic therapy (PDT) is a clinically approved therapeutic option for the treatment of various types of cancer. PDT calls for the application of photosensitizers (PSs) and photoactivation with a particular light wavelength while tissue oxygen is...

  • Review
  • Open Access
6 Citations
7,148 Views
31 Pages

Recent Advances in Application of Alkoxy Radical in Organic Synthesis

  • Munsaf Ali,
  • Shi Sewell,
  • Juncheng Li and
  • Ting Wang

28 September 2023

Alkoxy radicals have been identified as versatile intermediates in synthetic chemistry in the last few decades. Over the last decade, various catalytic processes for the in situ generation of alkoxy radicals have been explored, leading to the develop...

  • Article
  • Open Access
6 Citations
2,526 Views
12 Pages

The Use of a Natural Polysaccharide as a Solidifying Agent and Color-Fixing Agent on Modern Paper and Historical Materials

  • Lucia Emanuele,
  • Tanja Dujaković,
  • Graziella Roselli,
  • Simone Campanelli and
  • Giulia Bellesi

2 June 2023

This article presents results on the use of a new material as a solidifying agent and/or color-fixing agent. A special polysaccharide material extracted from the prickly pear cactus (Opuntia ficus indica) was tested on historical materials and modern...

  • Article
  • Open Access
6 Citations
3,562 Views
17 Pages

Triple Benefits of Cardanol as Chain Stopper, Flame Retardant and Reactive Diluent for Greener Alkyd Coating

  • Maxinne Denis,
  • Cédric Totée,
  • Damien Le Borgne,
  • Rodolphe Sonnier,
  • Sylvain Caillol and
  • Claire Negrell

15 March 2023

Cardanol, a waste from the food industry and widely produced (1 Mt/y), has been used as a chain stopper during the polycondensation of short oil alkyd resins in order to replace benzoic acid. Then, phosphorylated cardanol has been added in order to b...

  • Article
  • Open Access
6 Citations
2,164 Views
12 Pages

4 September 2023

In the present work, we report a thermoresponsive hydrogel formed by the self-assembly of compounds 1 and 2 Milli Q water. Both hydrogels showed thixotropic behavior. Atomic force microscopy (AFM) studies confirm the fiber-like microstructure of comp...

  • Article
  • Open Access
5 Citations
2,245 Views
13 Pages

Synthesis of Novel Trisubstituted Olefin-Type Probe Molecules Containing N-Heterocycles and Their Application in Detection of Malononitrile

  • Zhao-Hua Chen,
  • Shi-Wei Yu,
  • Wen-Jin Xu,
  • Miao-Xin Li,
  • Yong Zeng,
  • Si-Wei Deng,
  • Jian-Yun Lin and
  • Zhao-Yang Wang

2 April 2024

Recently, the construction of the trisubstituted olefin-type probe molecules has elicited the attention of many researchers. However, the synthesis of the trisubstituted olefin-type probes containing two N-heterocycles simultaneously has been rarely...

  • Article
  • Open Access
5 Citations
5,958 Views
17 Pages

12 October 2024

In this contribution, propylamine-functionalized cellulose (Cell-Pr-NH2) was employed as the catalyst in the three-component reaction between hydroxylamine hydrochloride and various types of aryl/heteroaryl aldehydes, ethyl acetoacetate/ethyl 4-chlor...

  • Review
  • Open Access
5 Citations
3,909 Views
18 Pages

Use and Roles of Tannins in Polysaccharide-Based Bioplastics and Biocomposites

  • Carlo Santulli,
  • Serena Gabrielli and
  • Graziella Roselli

1 May 2025

Most bioplastics are based on polysaccharides, which are either synthesized from a variously sourced monomer or extracted from some biomass waste. In many cases, some lignocellulosic fibers are then added to the obtained bioplastics to form biocompos...

  • Communication
  • Open Access
5 Citations
3,145 Views
9 Pages

Synthesis and Structure of 6-Acetyl-2-Arylhydrazone Derivatives of Thiazolo[3,2-a]Pyrimidine

  • Artem S. Agarkov,
  • Dilyara O. Mingazhetdinova,
  • Anna A. Nefedova,
  • Alexander S. Ovsyannikov,
  • Andrey K. Shiryaev,
  • Igor A. Litvinov,
  • Svetlana E. Solovieva and
  • Igor S. Antipin

11 August 2023

Triazolo[4,3-a]pyrimidine is one of the promising structural fragments for the development of drugs, including anticancer drugs. This work is devoted to the synthesis of a number of new 2-arylhydrazone derivatives of thiazolo[3,2-a]pyrimidine, which...

  • Review
  • Open Access
4 Citations
7,319 Views
23 Pages

4-Hydroxy-2-pyrones: Synthesis, Natural Products, and Application

  • Vladislav V. Fedin,
  • Dmitrii L. Obydennov,
  • Sergei A. Usachev and
  • Vyacheslav Y. Sosnovskikh

15 December 2023

4-Hydroxy-2-pyrones are of interest as potential biorenewable molecules for a sustainable transition from biomass feedstock to valuable chemical products. This review focuses on the methodologies for the synthesis of 4-hydroxy-2-pyrones published ove...

  • Article
  • Open Access
4 Citations
2,000 Views
8 Pages

New Generation of Hybrid Pyrazole–Tetrazole Tetrapodal Compounds: Synthesis and Biological Activities

  • Malika Amanchar,
  • Tarik Harit,
  • Mounir Cherfi,
  • Meryem Idrissi Yahyaoui,
  • Nour Elhouda Daoudi,
  • Abderrahmane Yahyi,
  • Abdeslam Asehraou and
  • Fouad Malek

4 September 2024

The elaboration of a new family of tetrapodal molecules L1L3 bearing two pyrazole–tetrazole units is presented. The structure assigned to such molecules was verified by various techniques, including FTIR, NMR, HRMS and elemental analysis...

  • Review
  • Open Access
4 Citations
4,950 Views
18 Pages

22 July 2024

In light of the small ring strain of five/six-membered cyclic ethers, constructing complex molecules via ring-opening reactions has consistently been a highly challenging topic in organic synthesis. Induced by Lewis acids, the charge redistribution i...

  • Communication
  • Open Access
4 Citations
7,522 Views
10 Pages

27 April 2023

We describe a novel two-step approach for the synthesis of compounds with a hydroxyl-amide group (hydroxamic acids), which are widely known for their biological activity (histone deacetylase inhibitors, matrix metalloproteinases inhibitors and others...

  • Review
  • Open Access
3 Citations
3,485 Views
12 Pages

5 June 2023

Great efforts of the scientific community are focused on the development of catalysts for the reduction of carbon dioxide (CO2) to useful molecules such as carbon monoxide, formic acid, methanol, ethanol, methane, ethylene, or acetate. Various metal...

  • Article
  • Open Access
3 Citations
2,230 Views
15 Pages

Amphiphilic Fluorescein Triazoles: Synthesis and Visible-Light Catalysis in Water

  • Alina Artemenko,
  • Elza Sultanova,
  • Diana Mironova,
  • Aliya Akhatova,
  • Ekaterina Bondareva,
  • Daut Islamov,
  • Konstantin Usachev,
  • Svetlana Solovieva,
  • Vladimir Burilov and
  • Igor Antipin

11 September 2024

Triazole derivatives of fluorescein-containing N,N-dimethylaminopropyl fragments and their ammonium salts were synthesized with yields of 74–85%. The resulting compounds exhibit fluorescent properties in the green region of the visible spectrum...

  • Review
  • Open Access
3 Citations
2,430 Views
17 Pages

An Overview of Some Reactive Routes to Flame-Retardant Fibre-Forming Polymers: Polypropylene and Polyacrylonitrile

  • Svetlana Tretsiakova-McNally,
  • Malavika Arun,
  • Maurice Guerrieri and
  • Paul Joseph

12 July 2023

The thermal degradation and flammability characteristics of some common fibre-forming polymers, such as polypropylene (PP) and polyacrylonitrile (PAN), are described in this review paper. The flame retardance of these polymers is principally affected...

  • Article
  • Open Access
3 Citations
2,673 Views
16 Pages

15 June 2023

Formaldehyde is a simple chemical compound that is used as a building block in obtaining a wide range of products. The versatility of formaldehyde in chemical synthesis becomes evident when it is reacted with N-alkylethylenediamines. Therefore, this...

  • Article
  • Open Access
3 Citations
2,673 Views
11 Pages

Cell Viability Study of ZnCuInS/ZnS–TPPS4 Conjugates against Different Cell Lines as a Promising Fluorescent Probe

  • Ncediwe Tsolekile,
  • Sundararajan Parani,
  • Thabang Calvin Lebepe,
  • Rodney Maluleke,
  • Vuyelwa Ncapayi,
  • Mangaka Clara Matoetoe,
  • Sandile Phinda Songca and
  • Oluwatobi Samuel Oluwafemi

17 March 2023

In the present work, we report a simple synthetic strategy for fabricating ZnCuInS/ZnS–TPPS4 conjugates and study its cytotoxicity as a promising material for imaging and phototherapy applications. The quaternary QDs were synthesized using eco-...

  • Review
  • Open Access
3 Citations
3,232 Views
21 Pages

Bispidine-Based Macrocycles: Achievements and Perspectives

  • Aleksei V. Medved’ko,
  • Savelii V. Gaisen,
  • Mikhail A. Kalinin and
  • Sergey Z. Vatsadze

24 July 2023

This review presents all currently known macroheterocyclic compounds that include a bispidine (3,7-diazabicyclo[3.3.1]nonane) fragment in their structure. A classification of bispidine-containing macroheterocycles, which is based on the ring size and...

  • Article
  • Open Access
3 Citations
2,891 Views
10 Pages

Computational Modeling of the Feasibility of Substituted [1.1.1]Propellane Formation from Anionic Bridgehead Bromide Precursors

  • Katherine E. Gates,
  • Caitlin Herring,
  • Andrew T. Lumpkin,
  • Robert J. Maraski,
  • Elizabeth G. Perry,
  • Madelen G. Prado,
  • Sarah L. Quigley,
  • Jazmine V. Ridlehoover,
  • Edith Salazar and
  • Gary W. Breton
  • + 5 authors

4 May 2023

[1.1.1]Propellane, a compound whose structure includes two saturated carbons in which all four bonds are directed into a single hemisphere, is of theoretical interest, but has also seen recent practical applications. Mono-, di-, and trisubstituted de...

  • Article
  • Open Access
2 Citations
2,239 Views
13 Pages

9 October 2023

The origin of individual features in the ground state absorption spectra of two protonated corroles differing in the architecture of peripheral substitution (either Cm-aryl or Cb-alkyl) have been studied in detail with the ground state absorption spe...

  • Article
  • Open Access
2 Citations
2,385 Views
11 Pages

Protolytic Equilibria of Cetirizine in the Presence of Micelle-Forming Surfactants

  • Marija Popović-Nikolić,
  • Gordana Popović,
  • Slavica Oljačić and
  • Katarina Nikolić

2 January 2025

The acid–base equilibria of cetirizine were investigated with and without the presence of differently charged micelle-forming surfactants (anionic, cationic, nonionic). The pKa values were potentiometrically determined at 25 °C and at a con...

  • Article
  • Open Access
2 Citations
3,610 Views
13 Pages

7 November 2024

In this study, we developed an efficient strategy for constructing thieno[3,2-b]thiophene molecules from 3-nitrothiophenes, containing carbonyl fragments at the C-2 and C-5 atoms, by nucleophilic aromatic substitution of the nitro group in these subs...

  • Article
  • Open Access
2 Citations
2,676 Views
11 Pages

Vinylation of Alcohols, Thiols, and Nitrogen Compounds Using a Stoichiometric Amount of In Situ Generated Acetylene

  • Maria S. Ledovskaya,
  • Vladimir V. Voronin,
  • Anna A. Reznichenko and
  • Ekaterina A. Reznichenko

8 February 2025

In this work, we developed a highly efficient and versatile environmentally benign methodology for the vinylation of a broad scope of substances, including alcohols, thiols, and nitrogen compounds. The key advantage of the proposed method is the use...

  • Article
  • Open Access
2 Citations
2,214 Views
14 Pages

22 December 2024

Various organic compounds susceptible to anodic polymerization were selected to study the effects of two solvents: acetic acid and ethyl acetate. Phenol and most of its derivatives, as well as resorcinol and 3,5-dihydroxybenzoic acid, exhibited typic...

  • Review
  • Open Access
2 Citations
2,665 Views
17 Pages

26 January 2025

Ferrocene is an organometallic compound that has attracted considerable scientific interest due to its unique properties, including low toxicity, excellent stability in aqueous and aerobic media, and high lipophilicity, which enhances membrane permea...

  • Article
  • Open Access
2 Citations
1,656 Views
13 Pages

Small Deviations in Geometries Affect Detonation Velocities and Pressures of Nitroaromatic Molecules

  • Danijela S. Kretić,
  • Marija I. Maslarević and
  • Dušan Ž. Veljković

9 April 2025

Understanding the factors that affect the detonation performance of high-energy molecules (HEMs) is crucial for the design of novel explosives and fuels with desirable characteristics. While molecular factors, such as the presence of specific functio...

  • Article
  • Open Access
2 Citations
2,030 Views
16 Pages

3 March 2025

The commercial flame-retardant 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide (DOPO) was almost quantitatively converted in sodium [2-(2-hydroxyphenyl)phenyl]phosphinate Na[OH-Ph-Ph-PHO2] and disodium 2-(2-phosphinatophenyl)benzen-1-olate Na2[O-P...

  • Article
  • Open Access
2 Citations
1,640 Views
14 Pages

28 November 2024

A simple approach was developed to efficiently graft diethylene triamine onto polystyrene waste using succinic anhydride as a tracer to remove nitrate anions from aqueous solutions. Infrared spectroscopic data showed characteristic signs at 3395 cm&m...

  • Review
  • Open Access
2 Citations
3,439 Views
17 Pages

Polycyclic Tetramate Macrolactams and Their Potential as Anticancer Agents

  • Alexandria Montavon,
  • M. Raquel Marchán-Rivadeneira and
  • Yong Han

27 September 2024

Natural products have been a reliable source of drug compounds in medical research. Technological advances have led to the discovery and characterization of many compounds that were previously difficult to isolate. However, when searching for antican...

  • Article
  • Open Access
2 Citations
2,620 Views
12 Pages

Innovative Application of Polyether Amine as a Recyclable Catalyst in Aerobic Thiophenol Oxidation

  • Lingxia Chen,
  • Junyu Li,
  • Ke Ni,
  • Xinshu Qin,
  • Lijun Wang,
  • Jiaman Hou,
  • Chao Wang,
  • Xuan Li,
  • Minlong Wang and
  • Jie An

26 April 2024

Polyether amines are versatile compounds characterized by a flexible structure, consisting of polyoxypropylene and polyoxyethylene as the backbone, with amine groups at each end. They have widespread applications in various industrial processes and d...

  • Review
  • Open Access
2 Citations
3,667 Views
40 Pages

How Much Potential Do Nucleoside Analogs Offer to Combat Human Corona Viruses?

  • Włodzimierz Buchowicz and
  • Mariola Koszytkowska-Stawińska

8 May 2024

Nucleoside analogs (NAs) have been extensively examined as plausible antiviral agents in recent years, in particular since the outbreak of the global pandemic of COVID-19 in 2019. In this review, the structures and antiviral properties of over 450 NA...

  • Article
  • Open Access
2 Citations
2,038 Views
11 Pages

14 February 2025

A series of photoacylations of 1,4-naphthoquinone with various aldehydes and using Pyrex-filtered UVB light was conducted under continuous-flow conditions. Acetone served as a triplet photosensitizer and convenient solvent that kept all materials in...

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Organics - ISSN 2673-401X