The digital platform market has evolved into a critical location for firms to engage in innovation and entrepreneurship. However, there is no clear answer to the question of when entrepreneurial firms should enter the digital platform market in order...
5 January 2024
To bolster their competitiveness and profitability, prominent e-commerce platforms have embraced dual retailing channels: self-operating channels and online marketplaces. However, a discernible trend is emerging wherein e-commerce platforms are expan...
The COVID-19 pandemic has led to the search for new molecules with antiviral activity against SARS-CoV-2. The entry of the virus into the cell is one of the main targets for inhibiting SARS-CoV-2 infection. Natural products are an important source of...
Test exploitation equipment and technology have progressed considerably in marine natural gas hydrate (NGH) exploitation, but many critical technical issues still need to be resolved before commercial production. Previous studies have proposed a non-...
22 September 2024
In the rapidly evolving platform economy, the competition between platform-owned products and third-party offerings is intensifying. This study examines the entry and pricing strategies of dominant e-commerce platforms such as Amazon and JD Mall whic...
Broadly neutralizing antibodies (bNAbs) are potent in neutralizing a wide range of HIV strains. VRC01 is a CD4-binding-site (CD4-bs) class of bNAbs that binds to the conserved CD4-binding region of HIV-1 envelope (env) protein. Natural products that...
The continuous entry of new firms and exit of old ones might have substantial effects on productivity of energy supply. Since China is the world’s largest energy producer, productivity of energy supply in China is a significant issue, which aff...
8 August 2025
With the rapid development of e-commerce, ensuring product quality on online platforms has become increasingly important, especially in developing countries where market regulations are still underdeveloped. By treating different sellers offering the...
Field trials of rice and bean dynamic mixtures were carried out in low input and hill farming systems of Nepal from 2019 to 2021 to improve productivity and resilience. The rice trials were conducted in two locations (Jumla and Lamjung) and those on...
The consumption of traditional wine has decreased in Europe during the last fifteen years. In parallel, new wine alternatives obtained by blending wines and fruit juices or by flavoring wines with artificial or natural flavors have appeared on the ma...
The interaction among the fuel ethanol industry, the technology system, and the market system has a substantial effect on the growth of the fuel ethanol industry which plays a key role in the formation of a sustainable energy system in China. However...
Hepatitis E virus (HEV) infection is one of the most common causes of acute hepatitis in the world. HEV is an enterically transmitted positive-strand RNA virus found as a non-enveloped particle in bile as well as stool and as a quasi-enveloped partic...
31 July 2017
Background: Cell and gene therapies have the potential to provide therapeutic breakthroughs, but the high costs of researching, developing, manufacturing and delivering them translate into prices that may challenge healthcare budgets. Various measure...
Conjugation of naturally occurring catecholic compounds with thiols is a versatile and facile entry to a broad range of bioinspired multifunctional compounds for diverse applications in biomedicine and materials science. We report herein the inhibiti...
Foreign market entry mode research has been a popular area of study. However, a clear agreement between the usage of conventional constructs and their impact on a firm’s entry mode choice has not yet been found. This paper focuses on how, depen...
The development of second-entry topical products is hampered by several factors. The excipient composition should be similar to the reference product because excipients may also contribute to efficacy. Conventional pharmacokinetic bioequivalence stud...
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the COVID-19 pandemic, has given rise to many new variants with increased transmissibility and the ability to evade vaccine protection. The 78-kDa glucose-regula...
HSV-1 major tegument protein VP22 is present in multiple subcellular locations in the late stages of productive viral infection. We initially performed a detailed time course experiment and observed that VP22 was detected in nuclear and nuclear matri...
The gut has been proposed as a potential alternative entry route for SARS-CoV-2. This was mainly based on the high levels of SARS-CoV-2 receptor expressed in the gastrointestinal (GI) tract, the observations of GI disorders (such as diarrhea) in some...
In this paper, we extend the analysis of farm structural change with respect to farm specialisation, size and exit in Norway by, first, explicitly incorporating the location information of farms generating a number of neighbouring farms within a cert...
Human respiratory syncytial virus (HRSV) is the most frequent cause of severe respiratory disease in children. The main targets of HRSV infection are epithelial cells of the respiratory tract, and the great majority of the studies regarding HRSV infe...
Cassia abbreviata is widely used in Sub-Saharan Africa for treating many diseases, including HIV-1 infection. We have recently described the chemical structures of 28 compounds isolated from an alcoholic crude extract of barks and roots of C. abbrevi...
Ebola virus (EBOV), one of the most infectious human viruses and a leading cause of viral hemorrhagic fever, imposes a potential public health threat with several recent outbreaks. Despite the difficulties associated with working with this pathogen i...
Viral infections and outbreaks have become a major concern and are one of the main causes of morbidity and mortality worldwide. The development of successful antiviral therapeutics and vaccines remains a daunting challenge. The discovery of novel ant...
Hepatitis B virus (HBV) relies on the core protein (HBc) to establish productive infection, as defined by the formation of the covalently closed circularized DNA (cccDNA), as well as to carry out almost every step of the lifecycle following cccDNA fo...
Increasing and sustainable production of rice in tropical hill area is facing various problems where rice ratooning can overcome the limitations. In this study; 22 rice entries were transplanted into experimental tank placed in the hill slope followi...
Hepatitis C virus (HCV) is a major cause of chronic hepatitis and liver disease worldwide. Its tissue and species tropism are largely defined by the viral entry process that is required for subsequent productive viral infection and establishment of c...
Gob-side entry retaining (GER) is a hot issue with regard to saving resources and reducing the drivage ratio in longwall mining. This paper investigates an innovative approach of roof presplitting for gob-side entry retaining (RPGER). RPGER uses the...
Sustainable development in coal mining requires a continuous and efficient method of coal extraction. Research shows that gob-side entries retained through roof cutting retained gob-side (RCGE) are vital for improving mining efficiency, enhancing coa...
In this paper, we compare using computational fluid dynamics the aero-thermal performance of two candidate casing manifolds for supplying an impingement-actuated active tip clearance control system for an aero-engine high-pressure turbine. The two ge...
COVID-19 has been impacting the Med-Tech industry dramatically since the beginning of 2020. Along with the pandemic continuously growing, the demand for major global medical products such as masks and protective clothing has surged. The Med-Tech indu...
Research on infectious severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) is currently restricted to BSL-3 laboratories. SARS-CoV2 virus-like particles (VLPs) offer a BSL-1, replication-incompetent system that can be used to evaluate virus a...
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The traditional gob-side entry-retaining mining method has problems such as difficulty in roof collapse and large deformation of the entry, which may affect the safety of mine production. In this study, we introduced a bidirectional blasting technolo...
The aim of the entry was to write a substantial contribution that analyses and compares the biological pollution of indoor air, the possibilities of its assessment and the control methods. In addition, the aim of our entry was to review journals cove...
Atmospheric corrosion is one of the major sources of hydrogen in a high-strength-steel product in service. Even low concentrations of absorbed hydrogen can cause a hydrogen embrittlement-related material degradation. The extent of atmospheric corrosi...
To establish a productive infection in host cells, viruses often use one or multiple host membrane glycoproteins as their receptors. For Influenza A virus (IAV) such a glycoprotein receptor has not been described, to date. Here we show that IAV is us...
The waste of coal resources, a complicated production process and slow mining speed seriously restrict the rapid development of longwall mining. To achieve effective mining, an innovative noncoal pillar mining approach (i.e., Gob-side Entry Retaining...
Chikungunya virus (CHIKV) is a re-emerging, mosquito-transmitted, enveloped positive stranded RNA virus. Chikungunya fever is characterized by acute and chronic debilitating arthritis. Although multiple host factors have been shown to enhance CHIKV i...
Zika virus (ZIKV; family, Flaviviridae), which causes congenital Zika syndrome, Guillain-Barré Syndrome, and other severe diseases, is transmitted mainly by mosquitoes; however, the virus can be transmitted through other routes. Among the thre...
Gob-side entry retaining, also termed as non-pillar mining, plays an important role in saving coal resources, high production and efficiency, extending the service life of mine and improving the investment benefit. Herein, a gob-side entry retaining...
Tomato is an important vegetable crop and plays a major role in the food and nutrition security of the people of Mali. Production has increased in the recent decades but improvement in the fruit yield and quality remains suboptimal. Limited access to...
H-1 protoparvovirus (H-1PV) is a self-propagating virus that is non-pathogenic in humans and has oncolytic and oncosuppressive activities. H-1PV is the first member of the Parvoviridae family to undergo clinical testing as an anticancer agent. Result...
Since the outbreak of COVID-19, researchers have been working tirelessly to discover effective ways to combat coronavirus infection. The use of computational drug repurposing methods and molecular docking has been instrumental in identifying compound...
Bombyx mori nucleopolyhedrovirus (BmNPV) is a serious viral pathogen in the sericulture industry and enters host cells via macropinocytic endocytosis; however, the current understanding of the BmNPV entry mechanism remains limited. To confirm whether...
Sustainable fashion refers to efforts to minimize the fashion industry’s adverse environmental and social impacts. This entry describes the industry’s entire production chain: from polyester production, cotton growth and wasteful fashion...
Live-cell imaging of single HIV-1 entry offers a unique opportunity to delineate the spatio-temporal regulation of infection. Novel virus labeling and imaging approaches enable the visualization of key steps of HIV-1 entry leading to nuclear import,...
The surface spike (S) glycoprotein mediates cell entry of SARS-CoV-2 into the host through fusion at the plasma membrane or endocytosis. Omicron lineages/sublineages have acquired extensive mutations in S to gain transmissibility advantages and alter...
This study considered the supply chain that two manufacturers sell green complementary products to a dominant offline retailer. We investigated whether a manufacturer (the integrated manufacturer) should add an online channel and examined how it affe...
Our objective is to describe the experience and challenges of using Managed Entry Agreements (MEAs) in Algeria, Morocco, and Tunisia. We conducted online interviews with key decision-makers in Algeria, Morocco, and Tunisia between March 2021 and Dece...
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