This paper discusses a cross-disciplinary, international collaboration aimed at researching a series of 15th century choir books at the abbey of San Giorgio Maggiore on the homonymous island in Venice. Produced for the abbey itself, the books have ne...
Biochemical investigations were carried out on the embalmed head of Nebiri (Museo Egizio, Turin; S-5109)—an 18th Dynasty Ancient Egyptian dignitary—and on the canopic jar containing his lungs (Museo Egizio, Turin; S. 5111/02) with the aim...
In the last decades, the working methods of late medieval illuminators have been widely discussed by art historians and codicologists. Non-invasive analyses are able to characterise the painting methods of illuminators as well as investigate artistic...
Naturally occurring and deeply coloured iron-bearing materials were exploited very early on by human populations. The characterization of these materials has proven useful for addressing several archaeological issues, such as the study of technical b...
The mosaic tesserae that are the topic of this study were found during an archeological excavation in a Roman villa at Aiano, in the municipality of San Gimignano, Tuscany (Italy). Many thousands of tesserae were found in the site in many different s...
The great white shark (Carcharodon carcharias), a keystone predator vital to marine ecosystem stability, is increasingly exposed to anthropogenic threats, including endocrine-disrupting chemicals (EDCs). This study highlights the use of non-invasive...
A multi-analytical study was carried out on an ancient Egyptian limestone stele with red figures and hieroglyphs (S. 6145) coming from the village of Deir el-Medina and belonging to the collection of the Museo Egizio (Turin, Italy). With the support...
The Lot Sarcophagus is one of the most relevant funerary sculptures of late antiquity (mid-4th century AC). Some of the remarkable aspects are the following (i) it is still preserved in situ; (ii) most of the carved scenes are rarities or unicum; (ii...
This study concerns the characterization of the color palette of Michelino da Besozzo, one of the leading painters and illuminators of the Late Gothic period in Northern Italy. The artist’s relationship with the color blue was investigated by c...
The Hebrew Scroll, catalogued as Magliabekian Manuscript III 43 and belonging to the National Central Library of Florence (BNCF), is a membranous richly decorated scroll, with colorful depictions of sacred sites through the Holy Land to Lebanon along...
This research deals with a multi-analytical approach to characterise three polychrome wooden crucifixes attributed to Fra’ Umile da Petralia or, in one case, close to his style. The analysed wooden sculptures belong to (1) the Sanctuary of Sain...
The Desana treasure is a remarkable assemblage of items made of gold, silver, gemstones and glasses found in north-western Italy. Most scholars agree on the fact that the core of the treasure might have belonged to a single deposit resulted from a lo...
In this paper, two different objects from the ethnographic collection of the museum of the Congregation of the Sacred Hearts of Jesus and Mary (Rome), a Polynesian barkcloth (tapa) and a Polynesian headdress in feathers (pa’e ku’a), were...
Wooden artefacts embrace wide-ranging types of objects, like paintings on panel, sculptures, musical instruments, and furniture. Generally, in the manufacturing process of an artwork, wood is firstly treated with organic and inorganic materials to ma...
The removal of non-original superimposed layers covering the original pictorial layer in paintings is a common practice to restore the authentic appearance of surfaces and mitigate potential risks to artwork preservation. Contemporary assessments of...
A monitoring campaign performed on the Real Site of Carditello (found in the commune of San Tammaro, province of Caserta, Italy) was aimed to evaluate the parameters related to air quality and then to control and prevent the degradation risk. The ana...
The National Museum of Rome has an important collection of Mithraic sculptures found in the years 1973–1975 during the archaeological excavation under the early Christian basilica of Santo Stefano Rotondo on the Caelian hill in Rome. The sculpt...
Rock art is a widespread cultural heritage, representing an immovable element of the material culture created on natural rocky supports. Paintings and petroglyphs can be found within caves and rock shelters or in open-air contexts and for that reason...
Monitoring programs should be based on the measurement of two main pillars for evaluating the conservation status of a species: population size and geographical distribution. To date, the only way reported in the literature to obtain detailed informa...
Imaging methods based on visible luminescence induced by ultraviolet (UV) radiation are well consolidated in the investigation of ancient works of art, to map varnishes, retouches, and possibly some pigments. As far as contemporary art is involved, t...
Two paintings, made on aluminium support by Silvio Pasotti (among the major exponents of 1960s Italian pop art) were investigated in a totally non-invasive manner to identify the materials used by the artist. Raman spectroscopy, Fourier-transform inf...
The treatment of colorectal cancer (CRC) has improved during the last decades, but methods for crucial early diagnosis are yet to be developed. The influence of the tumour microenvironment on liquid biopsies for early cancer diagnostics are gaining g...
The composition of the gut microbiome, defined by environmental factors, significantly affects research outcomes, with variations observed across animal facilities. Efforts to standardize led to the definition of the ‘Altered Schaedler flora&rs...
Genetic diversity plays a vital role in the adaptability of salmon to changing environmental conditions that can introduce new selective pressures on populations. Variability among local subpopulations may increase the chance that certain advantageou...
Two masterpieces of the Qing Dynasty (1644–1912 CE), one in gilded brass (incense burner) decorated with cloisonné enamels stylistically attributed to the end of the Kangxi Emperor’s reign, the other in gold (ewer offered by Napole...
The key to current Alzheimer’s disease (AD) therapy is the early diagnosis for prompt intervention, since available treatments only slow the disease progression. Therefore, this lack of promising therapies has called for diagnostic screening te...
Background/Objectives: Home non-invasive ventilation use is the primary treatment for improving respiratory function in people with chronic hypercapnic respiratory failure. Non-invasive ventilation has also been studied to understand users’ per...
Human respiratory activity parameters are important indicators of vital signs. Most respiratory activity detection methods are naïve abd simple and use invasive detection technology. Non-invasive breathing detection methods are the solution to t...
In the last decades, wildlife diseases and the health status of animal populations have gained increasing attention from the scientific community as part of a One Health framework. Furthermore, the need for non-invasive sampling methods with a minima...
A better understanding of interindividual differences and the development of targeted therapies is one of the major challenges of modern medicine. The sex of a person plays a crucial role in this regard. This systematic review aimed to summarise and...
In addition to characteristic and easily identifiable behavioural signs—namely epileptic seizures—electroencephalography (EEG) has long been a standard component of epilepsy diagnosis protocols. In veterinary practice, EEG is typically pe...
Despite new advancements in surgical tools and therapies, exposure to immunosuppressive drugs related to non-immune and immune injuries can cause slow deterioration and premature failure of organ transplants. Diagnosis of these injuries by non-invasi...
In recent decades, many works have been devoted to the study of materials and painting techniques used to produce illuminated manuscripts. If the analyses were once largely invasive, the approach has become increasingly more in situ and non-invasive...
Background: Invasive and non-invasive neuromodulation in psychiatry represents a burgeoning field that leverages advanced neuromodulation techniques to address substance use disorders (SUDs). Aims: This narrative review synthesizes findings from mult...
During the COVID-19 pandemic, the use of non-invasive respiratory support (NIRS) became crucial in treating patients with acute hypoxemic respiratory failure. Despite the fear of viral aerosolization, non-invasive respiratory support has gained atten...
Hemophilia is an X-linked recessive bleeding disorder. In pregnant women carrier of hemophilia, the fetal sex can be determined by non-invasive analysis of fetal DNA circulating in the maternal blood. However, in case of a male fetus, conventional in...
To minimise the influence of chromosomal abnormalities during IVF treatment, embryos can be screened before transfer using preimplantation genetic testing. This typically involves an invasive trophectoderm biopsy at the blastocyst stage, where 4&ndas...
Background and Objectives: The diagnosis and treatment of pituitary adenomas with cavernous sinus invasion pose significant challenges for clinicians. The objective of this study is to investigate the expression profile and prognostic value of HSPB1...
Intravitreal injection is the gold standard therapeutic option for posterior segment pathologies, and long-lasting release is necessary to avoid reinjections. There is no effective intravitreal treatment for glaucoma or other optic neuropathies in da...
Since 1997, scientists have been trying to utilize new non-invasive approaches for thermal discomfort detection, which promise to be more effective for comparing frameworks that need direct responses from users. Due to rapid technological development...
Background: The use of inert gas rebreathing for the non-invasive cardiac output measurement has produced measurements comparable to those obtained by various other methods. However, there are no guidelines for the inert gas rebreathing method during...
Wildlife research has been indispensable for increasing our insight into ecosystem functioning as well as for designing effective conservation measures under the currently high rates of biodiversity loss. Genetic and genomic analyses might be able to...
This study aims to elucidate the level of DNA methylation in urothelial carcinomas (UCs) using 5-methylcytosine (5-MeC) immunohistochemistry (IHC). We examined the relationship among 5-MeC levels, DNA (cytosine-5)-methyltransferase 1 (DNMT1) immunost...
Background: Atrial fibrosis is a key contributor to atrial cardiomyopathy and can be assessed invasively using mean left atrial voltage (MLAV) from electroanatomical mapping. However, the invasive nature of this procedure limits its clinical applicab...
In the present work, a method is proposed that combines spectrofluorimetry with multivariate analysis (cluster and principal components) to non-invasively investigate natural dyes used, mainly in the form of lakes, in illuminations. First, a consiste...
The modern decoration of the Saint Nicolas de Myre Church at Semsales (1924–1926), is the first by renowned Italian artist Gino Severini in Switzerland. Following archival research and visual examination, the materials and the techniques used by Seve...
Objectives: This systematic review aimed to analyse the published evidence for the use of non-invasive methods for the early detection of oral squamous cell carcinoma (OSCC) and oral potentially malignant disorders (OPMDs). Methods: The literature wa...
This study is concerned with recent analyses of seven marble statues from the imperial cycle of the Augusteum of Rusellae, in the south of Tuscany, Italy. The sculptures represent the deified couple Augustus and Livia, Livilla, Claudius, an anonymous...
Debris flows represent a significant geohydrological hazard, impacting the surrounding environment and threatening human settlements by altering ecological equilibria. The formation of temporary, often unstable, natural dams that obstruct normal rive...
Skin diseases and disorders have a significant impact on people’s health and quality of life. Current medical practice suggests different methodologies for detecting and diagnosing skin diseases and conditions. Most of these require medical tes...
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