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170 Results Found

  • Article
  • Open Access
404 Views
15 Pages

Background: Substance Use Disorder (SUD) is more prevalent among individuals with psychotic disorders than in the general population and is associated with poorer functioning, treatment adherence, and outcomes. Understanding motives for substance use...

  • Article
  • Open Access
20 Citations
8,322 Views
14 Pages

Substance Use and Attendance Motives of Electronic Dance Music (EDM) Event Attendees: A Survey Study

  • Edith Van Dyck,
  • Koen Ponnet,
  • Tina Van Havere,
  • Bert Hauspie,
  • Nicky Dirkx,
  • Jochen Schrooten,
  • Jon Waldron,
  • Meryem Grabski,
  • Tom P. Freeman and
  • Jan De Neve
  • + 1 author

EDM event attendees are a high-risk population for substance use and associated adverse effects. The aim of this study was to examine substance use at EDM events, focusing on associations between attendance motives and substance use. Sociodemographic...

  • Project Report
  • Open Access
12 Citations
6,496 Views
9 Pages

Motivational interviewing (MI) has been increasingly utilized by health care practitioners for many years. MI has been practiced by social workers, nurses, physicians, psychologists, substance use counselors, and many other health care practitioners....

  • Article
  • Open Access
2 Citations
1,946 Views
15 Pages

Background: Alcohol and substance use among young people is a well-documented public health concern, and is particularly prevalent in college populations. Problematic internet use is also an emerging issue, with potential negative effects on academic...

  • Article
  • Open Access
1 Citations
1,365 Views
15 Pages

The current investigation examines pathways linking individual risk factors, namely maladaptive emotion regulation, behavior problems, and drinking motives, with adolescents’ alcohol consumption. In a cross-sectional design, 243 adolescents att...

  • Article
  • Open Access
25 Citations
10,813 Views
14 Pages

Patterns of and Motivations for Concurrent Use of Video Games and Substances

  • Geoffrey L. Ream,
  • Luther C. Elliott and
  • Eloise Dunlap

“Behavioral addictions” share biological mechanisms with substance dependence, and “drug interactions” have been observed between certain substances and self-reinforcing behaviors. This study examines correlates of patterns of and motivations for pla...

  • Article
  • Open Access
4 Citations
5,304 Views
15 Pages

29 December 2023

Drug use is increasing in South Korea, necessitating evidence-based policy interventions. However, there is a dearth of reliable tools for identifying the personal and psychological factors that drive drug use among Korean adults. In this study, we d...

  • Article
  • Open Access
4 Citations
4,564 Views
10 Pages

19 February 2023

This study examined the prevalence of illegal drug use in UK students and motivators behind such behavior. Additionally, we explored possible relationships between substance use, psychosocial motivators, and psychiatric distress. A group (n = 543) of...

  • Article
  • Open Access
2,000 Views
15 Pages

Characterizing Engagement with Web-Based Screening, Brief Intervention, and Referral to Treatment (SBIRT) for Traumatic Stress and Substance Misuse After Interpersonal Violence

  • Alexandra N. Brockdorf,
  • Emily L. Tilstra-Ferrell,
  • Carla K. Danielson,
  • Angela D. Moreland,
  • Alyssa A. Rheingold,
  • Selime R. Salim,
  • Amanda K. Gilmore,
  • Rachel E. Siciliano,
  • Daniel W. Smith and
  • Christine K. Hahn

Screening, brief intervention, and referral to treatment (SBIRT) is a widely used public health approach for delivering early intervention for substance misuse. SBIRT adaptations that incorporate content on interpersonal violence and posttraumatic st...

  • Article
  • Open Access
336 Views
15 Pages

Substance use among university students is a complex phenomenon influenced by sociodemographic, contextual, and psychosocial factors, with direct implications for wellbeing and social-emotional learning. This study examined the relationships between...

  • Article
  • Open Access
6 Citations
2,531 Views
8 Pages

Analyzing the Behavior of Cannabis Users during the COVID-19 Confinement in Spain

  • Sergio Fernández-Artamendi,
  • Manuel J. Ruiz and
  • Carla López-Núñez

The impact of the COVID-19 pandemic on our lives is unquestionable, including in the area of substance consumption. This study aimed to evaluate the changes in the pattern of cannabis use during the Spanish COVID-19 lockdown and confinement, and to a...

  • Article
  • Open Access
937 Views
10 Pages

Young Smokers’ Therapy Preferences: App-Based vs. Face-to-Face Treatment in the Context of Co-Addictions

  • Francisca López-Torrecillas,
  • María del Mar Arcos-Rueda,
  • Beatriz Cobo-Rodríguez and
  • Lucas Muñoz-López

17 September 2025

Background: Tobacco use remains a major public health concern among young adults and is often complicated by co-occurring addictive behaviors. Objective: This study analyzed motivation for change, assessed with the decisional balance framework, in re...

  • Article
  • Open Access
2 Citations
4,604 Views
12 Pages

Self-Medication: Attitudes and Behaviors Among Pharmacy and Medical Students

  • George Jîtcă,
  • Carmen-Maria Jîtcă,
  • Mădălina-Georgiana Buț and
  • Camil-Eugen Vari

4 September 2025

Self-medication is increasingly prevalent among healthcare students, raising concerns about the adequacy of current medical education in promoting safe medication practices. This study aimed to assess the frequency, motivations, and perceptions of se...

  • Article
  • Open Access
17 Citations
3,895 Views
11 Pages

Experiences of Parents with Opioid Use Disorder during Their Attempts to Seek Treatment: A Qualitative Analysis

  • Christine Bakos-Block,
  • Angela J. Nash,
  • A. Sarah Cohen and
  • Tiffany Champagne-Langabeer

In the U.S., 12.3% of children live with at least one parent who has a substance use disorder. Prior research has shown that men are more likely to seek treatment than women and that the barriers are different; however, there is limited research focu...

  • Review
  • Open Access
3 Citations
12,797 Views
58 Pages

Unveiling the Complexities of Medications, Substance Abuse, and Plants for Recreational and Narcotic Purposes: An In-Depth Analysis

  • Iasmina-Alexandra Predescu,
  • Alex-Robert Jîjie,
  • Dalia Pătraşcu,
  • Aida-Luisa-Vanessa Pasc,
  • Elisaveta-Ligia Piroş,
  • Cristina Trandafirescu,
  • Cristian Oancea,
  • Cristina Adriana Dehelean and
  • Elena-Alina Moacă

22 January 2025

The complexities surrounding the use of medications, substance abuse, and the recreational use of plants are multifaceted and warrant a comprehensive examination. This review highlights the complexities surrounding the consumption of chemical substan...

  • Article
  • Open Access
18 Citations
4,351 Views
12 Pages

Changes in Substance Use and Mental Health Burden among Women during the Second Wave of COVID-19 in Germany

  • Henrike Schecke,
  • Madeleine Fink,
  • Alexander Bäuerle,
  • Eva-Maria Skoda,
  • Adam Schweda,
  • Venja Musche,
  • Hannah Dinse,
  • Benjamin Maurice Weismüller,
  • Sheila Moradian and
  • Martin Teufel
  • + 1 author

Unlike men, who are disproportionately affected by severe disease progression and mortality from COVID-19, women may be more affected by the economic, social and psychological consequences of the pandemic. Psychological distress and mental health pro...

  • Article
  • Open Access
10 Citations
4,219 Views
13 Pages

Motivating Pregnant and Breastfeeding Women in Spain to Avoid Persistent Toxic Substances in Their Diet

  • Andres Fontalba-Navas,
  • Eva Zafra Aparici,
  • Maria Clara de Moraes Prata-Gaspar,
  • Esther Herrera-Espejo,
  • Miguel Company-Morales and
  • Cristina Larrea-Killinger

The objective of this study was to explore what motivates pregnant and breastfeeding women to make changes in their diet, specifically to examine how their perceptions regarding diet facilitate or act as obstacles to introducing healthy eating habits...

  • Article
  • Open Access
8 Citations
10,656 Views
15 Pages

The Design and Application of Game Rewards in Youth Addiction Care

  • Marierose M. M. van Dooren,
  • Valentijn T. Visch and
  • Renske Spijkerman

6 April 2019

Different types of rewards are applied in persuasive games to encourage play persistence of its users and facilitate the achievement of desired real-world goals, such as behavioral change. Persuasive games have successfully been applied in mental hea...

  • Article
  • Open Access
25 Citations
10,617 Views
20 Pages

Substance misuse services need to meet the growing demand and needs of individuals using new psychoactive substances (NPS). A review of the literature identified a paucity of research regarding NPS use by these individuals and UK guidelines outline t...

  • Article
  • Open Access
13 Citations
5,860 Views
16 Pages

Substitute Behaviors following Residential Substance Use Treatment in the Western Cape, South Africa

  • Deborah Louise Sinclair,
  • Steve Sussman,
  • Maarten De Schryver,
  • Cedric Samyn,
  • Sabirah Adams,
  • Maria Florence,
  • Shazly Savahl and
  • Wouter Vanderplasschen

The dynamics of substitute behaviors and associated factors remain poorly understood globally, and particularly in low- and middle-income contexts. This prospective study describes the prevalence and types of substitute behaviors as well as predictor...

  • Article
  • Open Access
5 Citations
3,352 Views
12 Pages

Analysis of Relationships between DAT1 Polymorphism Variants, Personality Dimensions, and Anxiety in New Psychoactive Substance (Designer Drug) (NPS) Users

  • Jolanta Chmielowiec,
  • Krzysztof Chmielowiec,
  • Jolanta Masiak,
  • Tomasz Pawłowski,
  • Dariusz Larysz and
  • Anna Grzywacz

10 December 2021

The use of ‘new psychoactive substances’ appears to be increasingly common. The aim of this study was to examine biological and personality determinants in individuals who choose to use these substances, which may help in the prevention a...

  • Review
  • Open Access
204 Views
25 Pages

5 July 2026

Individual differences in the sensitivity and response to drugs of abuse are reliably associated with later patterns of substance use and, for some, progression to a substance use disorder diagnosis. This review synthesizes human drug challenge, long...

  • Article
  • Open Access
7 Citations
5,174 Views
16 Pages

Do Coping Motives and Perceived Impaired Control Mediate the Indirect Links from Childhood Trauma Facets to Alcohol-Related Problems?

  • Jai Bitsoih,
  • Julie A. Patock-Peckham,
  • Jessica R. Canning,
  • Annie Ong,
  • Allison Becerra and
  • Matthew Broussard

23 February 2023

Introduction: The Self-Medication Hypothesis suggests that individuals drink to alleviate undesirable affective states. Behavioral Economics Theory states that individuals deprived of resources (i.e., physically neglected) consume more reinforcing su...

  • Article
  • Open Access
1 Citations
3,417 Views
12 Pages

Cannabis Use in Opioid Maintenance Therapy: Prevalence, Clinical Correlates and Reasons for Use

  • Markus Backmund,
  • Greta G. Zámbó,
  • Susanne Schöfl and
  • Michael Soyka

Background and aims: Opioid maintenance therapy (OMT) is the first-line treatment for opioid use disorder (OUD), reducing opioid use and mortality while improving physical and mental health. However, concomitant substance use remains common, with can...

  • Article
  • Open Access
1 Citations
1,676 Views
16 Pages

Adolescence is a critical period during which alcohol is the most commonly used substance worldwide, and such use has detrimental effects on neurobiological, psychosocial, and physiological development. Despite substantial international evidence, lit...

  • Review
  • Open Access
2,325 Views
17 Pages

Dopamine and Acetylcholine in the Striatum: Circuit Interactions and Behavioral Control in Substance Use Disorders

  • Oyku Dinckol,
  • Noah H. Wenger,
  • Aryanna Copling,
  • Bhumiben P. Patel and
  • Munir Gunes Kutlu

Substance use disorder (SUD) is a chronic neuropsychiatric condition characterized by persistent drug seeking and impaired behavioral control. Dopaminergic signaling has long been recognized as a central regulator of reinforcement learning, motivatio...

  • Review
  • Open Access
4,291 Views
15 Pages

Chemsex: Venereological Consequences, Psychiatric and Somatic Complications, and Potential Intervention Strategies

  • Hasan Selcuk Ozkan,
  • Stefania-Cristina Rogoveanu and
  • Damla Isman-Haznedaroglu

Background/Objectives: Chemsex is defined as the intentional use of psychoactive substances to enhance or prolong sexual activity, predominantly observed among men who have sex with men. It has emerged as a notable behavioral and public health concer...

  • Article
  • Open Access
2,291 Views
11 Pages

Native American (NA) communities are disproportionately affected by the intersecting, synergistic epidemics of sexually transmitted infections (STIs) and substance use. Targeted approaches to addressing these syndemics are critical given the relative...

  • Article
  • Open Access
14 Citations
4,346 Views
13 Pages

Cigarette Smoking and Dating App Use: Findings from a Survey in a Sample of Adults in Italy

  • Luca Flesia,
  • Valentina Fietta,
  • Carlo Foresta and
  • Merylin Monaro

Existing studies in the literature indicate an association between the use of dating apps and substance-related behaviours (i.e., alcohol consumption, drug consumption). However, to date, no studies investigated the relation between dating app use an...

  • Review
  • Open Access
7 Citations
152 Views

Therapie der Opioidabhängigkeit – ein Update

  • Marc Vogel,
  • Sylvie Petitjean,
  • Stefan Borgwardt,
  • Gerhard A. Wiesbeck and
  • Marc Walter
Swiss Arch. Neurol. Psychiatry Psychother.2010, 161(1), 5-13;https://doi.org/10.4414/sanp.2010.02125 
(registering DOI)

1 January 2010

After the heroin-wave in Switzerland in the 1980s and 1990s and the establishment of successful maintenance therapies for harm reduction in many western countries, the first evidence-based guidelines for the treatment of opioid dependence appeared. P...

  • Article
  • Open Access
2,235 Views
15 Pages

“FLIPPED ASSESSMENT”: Proposal for a Self-Assessment Method to Improve Learning in the Field of Manufacturing Technologies

  • José Díaz-Álvarez,
  • Antonio Díaz-Álvarez,
  • Ramiro Mantecón and
  • María Henar Miguélez

15 August 2023

Striving toward goal completion and achieving objectives is one of the motors of personal advancement. The path to goal completion is fueled by many reasons, among which motivation stands out as one of the core impulses. Motivation acquires a particu...

  • Review
  • Open Access
71 Citations
7,572 Views
20 Pages

Application of Rosmarinic Acid with Its Derivatives in the Treatment of Microbial Pathogens

  • Ourdia-Nouara Kernou,
  • Zahra Azzouz,
  • Khodir Madani and
  • Patricia Rijo

The emergence of the antimicrobial resistance phenomena on and the harmful consequences of the use of antibiotics motivate the necessity of innovative antimicrobial therapies, while natural substances are considered a promising alternative. Rosmarin...

  • Perspective
  • Open Access
29 Citations
17,276 Views
15 Pages

Dopamine Pharmacodynamics: New Insights

  • Fulvio Lauretani,
  • Francesco Giallauria,
  • Crescenzo Testa,
  • Claudia Zinni,
  • Beatrice Lorenzi,
  • Irene Zucchini,
  • Marco Salvi,
  • Raffaele Napoli and
  • Marcello Giuseppe Maggio

Dopamine is a key neurotransmitter involved in physiological processes such as motor control, motivation, reward, cognitive function, and maternal and reproductive behaviors. Therefore, dysfunctions of the dopaminergic system are related to a plethor...

  • Article
  • Open Access
2,595 Views
11 Pages

Individuals with substance abuse disorders experience trouble with the return to work or finding a stable workplace. At the same time, unemployment has negative effects on substance abuse. Work-related case management programs are often used to suppo...

  • Article
  • Open Access
19 Citations
5,037 Views
15 Pages

Understanding Sexualized Drug Use: Substances, Reasons, Consequences, and Self-Perceptions among Men Who Have Sex with Other Men in Spain

  • Daniel Íncera-Fernández,
  • Francisco J. Román,
  • Santiago Moreno-Guillén and
  • Manuel Gámez-Guadix

Sexualized drug use (SDU) has been identified as a health risk factor among gay, bisexual, and other men who have sex with men (GBMSM). This study aimed to analyze the associations between SDU frequency and a broad set of substances, motives, consequ...

  • Review
  • Open Access
1 Citations
1,520 Views
29 Pages

Incretin-Based Therapies: A Novel Pathway in Addiction Treatment

  • Rosiejka Dawid,
  • Michałowska Joanna,
  • Marcickiewicz Justyna,
  • Adela Bogdańska,
  • Wiktoria Błażejewska and
  • Monika Szulińska

19 February 2026

Addiction poses a major global public health challenge. It is characterized by high prevalence, chronic relapse and limited efficacy of available pharmacotherapies across different substance use disorders. Increasing evidence demonstrates that incret...

  • Article
  • Open Access
10 Citations
8,126 Views
13 Pages

Motivations for Caffeine Consumption in New Zealand Tertiary Students

  • Saskia Stachyshyn,
  • Carol Wham,
  • Ajmol Ali,
  • Tayla Knightbridge-Eager and
  • Kay Rutherfurd-Markwick

25 November 2021

Caffeine-related health incidents in New Zealand have escalated over the last two decades. In order to reduce the risk of substance-related harm, it is important to understand the consumers’ motivations for its use. This is especially true for...

  • Article
  • Open Access
1 Citations
4,382 Views
17 Pages

Validation of a Questionnaire of Motivations for Moderated and Severe Alcohol Consumption Among College Students

  • Abel Lerma,
  • Jorge Alberto Soto-Huerta,
  • Cristina J. González-Flores,
  • Rebeca María Elena Guzmán-Saldaña,
  • Diego Aguirre-Villegas and
  • Claudia Lerma

2 February 2025

Objective: This work aimed to develop and validate a scale to assess motivations for alcohol drinking among Mexican college students. Methods: The scale design consisted of applying a stimulus phrase to assess motivations for moderate alcohol drinkin...

  • Review
  • Open Access
16 Citations
7,731 Views
17 Pages

Vaccines to Treat Substance Use Disorders: Current Status and Future Directions

  • Tangsheng Lu,
  • Xue Li,
  • Wei Zheng,
  • Chenyan Kuang,
  • Bingyi Wu,
  • Xiaoxing Liu,
  • Yanxue Xue,
  • Jie Shi,
  • Lin Lu and
  • Ying Han

Addiction, particularly in relation to psychostimulants and opioids, persists as a global health crisis with profound social and economic ramifications. Traditional interventions, including medications and behavioral therapies, often encounter limite...

  • Article
  • Open Access
9 Citations
7,886 Views
11 Pages

12 May 2024

Excessive alcohol use, as well as drinking to manage distress, are known to undermine mental health. The current study examined the unique associations of simply consuming alcohol while stressed, versus using alcohol to cope with distress, with menta...

  • Article
  • Open Access
8 Citations
5,262 Views
17 Pages

Alcohol and cannabis use are highly prevalent among adolescents and associated with negative consequences. Understanding motivations behind substance use in youth is important for informing prevention and intervention efforts. The present study aims...

  • Review
  • Open Access
18 Citations
11,045 Views
47 Pages

Biomarkers of the Endocannabinoid System in Substance Use Disorders

  • Francisco Navarrete,
  • María S. García-Gutiérrez,
  • Ani Gasparyan,
  • Daniela Navarro,
  • Francisco López-Picón,
  • Álvaro Morcuende,
  • Teresa Femenía and
  • Jorge Manzanares

3 March 2022

Despite substance use disorders (SUD) being one of the leading causes of disability and mortality globally, available therapeutic approaches remain ineffective. The difficulty in accurately characterizing the neurobiological mechanisms involved with...

  • Review
  • Open Access
22 Citations
7,079 Views
14 Pages

Prescription opioids are potent analgesics that are used for clinical pain management. However, the nonmedical use of these medications has emerged as a major concern because of dramatic increases in abuse and overdose. Therefore, effective strategie...

  • Article
  • Open Access
3 Citations
1,642 Views
17 Pages

10 July 2023

Spiking neural P systems (SNP systems), as computational models abstracted by the biological nervous system, have been a major research topic in biological computing. In conventional SNP systems, the rules in a neuron remain unchanged during the comp...

  • Article
  • Open Access
32 Citations
7,467 Views
18 Pages

Within Canada, several specialized multi-service prevention programs work with highly vulnerable pregnant and early parenting women with substance use issues. Experiences of trauma, mental health, poverty, and other factors associated with the social...

  • Perspective
  • Open Access
17 Citations
16,188 Views
12 Pages

The global issue of substance abuse demands ongoing initiatives aligned with the United Nations Sustainable Development Goals. With drug use remaining prevalent worldwide, interventions are critical to addressing the associated health challenges and...

  • Article
  • Open Access
35 Citations
6,797 Views
17 Pages

Problematic Use of Nitrous Oxide by Young Moroccan–Dutch Adults

  • Ton Nabben,
  • Jelmer Weijs and
  • Jan van Amsterdam

The recreational use of nitrous oxide (N2O; laughing gas) has largely expanded in recent years. Although incidental use of nitrous oxide hardly causes any health damage, problematic or heavy use of nitrous oxide can lead to serious adverse effects. A...

  • Review
  • Open Access
1 Citations
3,082 Views
46 Pages

Clinical and animal studies suggest that multiple brain systems are involved in mediating reward-motivated and related emotional behavior including the consumption of commonly used drugs and palatable food, and there is evidence that the repeated ing...

  • Article
  • Open Access
7 Citations
5,293 Views
13 Pages

Neuroenhancement in French and Romanian University Students, Motivations and Associated Factors

  • Irina Brumboiu,
  • Alessandro Porrovecchio,
  • Thierry Peze,
  • Remy Hurdiel,
  • Irina Cazacu,
  • Cristina Mogosan,
  • Joel Ladner and
  • Marie-Pierre Tavolacci

This cross-sectional study aimed to determine the use of neuroenhancers, the motivations and factors associated with their use in French and Romanian university students. Students from two universities in France (Rouen and Opal Coast University) and...

  • Article
  • Open Access
7 Citations
3,642 Views
11 Pages

Healthcare Providers’ Perceptions about the Role of Spiritual Care and Chaplaincy Services in Substance Use Outpatient Treatment

  • Brian S. W. Earl,
  • Anne Klee,
  • Ellen L. Edens,
  • James D. Cooke,
  • Holly Heikkila and
  • Lauretta E. Grau

Addressing patients’ religion and spirituality (R/S) needs has been associated with positive health outcomes. However, despite receiving extensive training in spiritual assessment and care, chaplaincy services are primarily confined to inpatien...

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