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78 Results Found

  • Article
  • Open Access
26 Citations
7,064 Views
8 Pages

Highly Sensitive Measurement of Liquid Density in Air Using Suspended Microcapillary Resonators

  • Oscar Malvar,
  • Daniel Ramos,
  • Carmen Martínez,
  • Priscila Kosaka,
  • Javier Tamayo and
  • Montserrat Calleja

30 March 2015

We report the use of commercially available glass microcapillaries as micromechanical resonators for real-time monitoring of the mass density of a liquid that flows through the capillary. The vibration of a suspended region of the microcapillary is o...

  • Article
  • Open Access
2,263 Views
12 Pages

13 March 2025

In this study, we designed and experimentally demonstrated an all–optical tuning system based on the absorption effect of magnetic nanoparticles on a pump light. The all-optical tuning process induces a temperature change in the microcavity&nda...

  • Article
  • Open Access
2 Citations
1,888 Views
16 Pages

12 September 2023

By utilizing hydrogen as an eco-friendly energy source, many metals are exposed to gaseous (pressurized) hydrogen. High-strength steels with an ultimate tensile strength of 800 MPa and above are especially susceptible to hydrogen-induced fracturing,...

  • Article
  • Open Access
10 Citations
5,143 Views
24 Pages

27 July 2017

In this work, a non-isothermal electroosmotic flow of two immiscible fluids within a uniform microcapillary is theoretically studied. It is considered that there is an annular layer of a non-Newtonian liquid, whose behavior follows the power-law mode...

  • Feature Paper
  • Article
  • Open Access
2,531 Views
15 Pages

18 November 2024

During phagocytosis, the FcGR–IgG bond is thought to be necessary to promote cell-membrane extension as the zipper mechanism. However, does this zipper mechanism provide a spatial antigen discrimination capability that allows macrophages to sel...

  • Article
  • Open Access
17 Citations
6,718 Views
12 Pages

Micro-Capillary Coatings Based on Spiropyran Polymeric Brushes for Metal Ion Binding, Detection, and Release in Continuous Flow

  • Aishling Dunne,
  • Colm Delaney,
  • Aoife McKeon,
  • Pavel Nesterenko,
  • Brett Paull,
  • Fernando Benito-Lopez,
  • Dermot Diamond and
  • Larisa Florea

4 April 2018

Micro-capillaries, capable of light-regulated binding and qualitative detection of divalent metal ions in continuous flow, have been realised through functionalisation with spiropyran photochromic brush-type coatings. Upon irradiation with UV light,...

  • Article
  • Open Access
10 Citations
4,486 Views
12 Pages

14 February 2020

In this work, we demonstrate spectral phase-shift interferometry operating in the near-infrared wavelength range for refractive index (RI) monitoring of fluidic samples in micro-capillaries. A detailed theoretical model was developed to calculate the...

  • Proceeding Paper
  • Open Access
5 Citations
2,361 Views
6 Pages

14 November 2020

In this work, we present a micro-opto-fluidic platform to distinguish water and alcohol samples flowing in rectangular glass micro-capillaries laid onto a bulk Aluminum mirror illuminated by the broadband radiation emitted by a Tungsten lamp. The flu...

  • Article
  • Open Access
13 Citations
6,484 Views
12 Pages

Low-Coherence Reflectometry for Refractive Index Measurements of Cells in Micro-Capillaries

  • Francesca Carpignano,
  • Giulia Rigamonti,
  • Giuliano Mazzini and
  • Sabina Merlo

11 October 2016

The refractive index of cells provides insights into their composition, organization and function. Moreover, a good knowledge of the cell refractive index would allow an improvement of optical cytometric and diagnostic systems. Although interferometr...

  • Article
  • Open Access
12 Citations
3,014 Views
9 Pages

Coherent Optical Transduction of Suspended Microcapillary Resonators for Multi-Parameter Sensing Applications

  • Alberto Martín-Pérez,
  • Daniel Ramos,
  • Javier Tamayo and
  • Montserrat Calleja

20 November 2019

Characterization of micro and nanoparticle mass has become increasingly relevant in a wide range of fields, from materials science to drug development. The real-time analysis of complex mixtures in liquids demands very high mass sensitivity and high...

  • Article
  • Open Access
1,554 Views
20 Pages

29 September 2023

A challenging issue is currently the design of non-fibrous ultra-thin acoustic absorbers that are able to provide broadband performance in demanding environments. The objective of this study is to compare using simulations and measurements the broadb...

  • Article
  • Open Access
12 Citations
3,294 Views
13 Pages

A Micron-Range Displacement Sensor Based on Thermo-Optically Tuned Whispering Gallery Modes in a Microcapillary Resonator

  • Zhe Wang,
  • Arun Kumar Mallik,
  • Fangfang Wei,
  • Zhuochen Wang,
  • Anuradha Rout,
  • Qiang Wu and
  • Yuliya Semenova

29 October 2022

A novel micron-range displacement sensor based on a whispering-gallery mode (WGM) microcapillary resonator filled with a nematic liquid crystal (LC) and a magnetic nanoparticle- coated fiber half-taper is proposed and experimentally demonstrated. In...

  • Article
  • Open Access
9 Citations
4,540 Views
13 Pages

28 November 2017

Due to the increasingly wide application of electroosmotic flow in micromachines, this paper investigates the electroosmotic flow of the power-law fluid under high zeta potential in a cylindrical microcapillary for different dimensionless parameters....

  • Article
  • Open Access
16 Citations
5,650 Views
15 Pages

Deciphering Hydrodynamic and Drug-Resistant Behaviors of Metastatic EMT Breast Cancer Cells Moving in a Constricted Microcapillary

  • Binita Nath,
  • Anil P. Bidkar,
  • Vikash Kumar,
  • Amaresh Dalal,
  • Mohit Kumar Jolly,
  • Siddhartha S. Ghosh and
  • Gautam Biswas

9 August 2019

Epithelial to mesenchymal transition (EMT) induces cell migration, invasion, and drug resistance, and consequently, contributes to cancer metastasis and disease aggressiveness. This study attempted to address crucial biological parameters to correlat...

  • Article
  • Open Access
2 Citations
4,186 Views
15 Pages

8 May 2019

In indirect inertial confinement fusion (ICF), the prediction of gas pressures and mass flow rates in the hohlraum is critical for fielding the hohlraum film and the support tent. To this end, it is desirable to understand the gas filling and evacuat...

  • Article
  • Open Access
1 Citations
4,189 Views
15 Pages

Looping Flexible Fluoropolymer Microcapillary Film Extends Analysis Times for Vertical Microfluidic Blood Testing

  • Rüya Meltem Sarıyer,
  • Kirandeep K. Gill,
  • Sarah H. Needs,
  • Nuno M. Reis,
  • Chris I. Jones and
  • Alexander Daniel Edwards

10 September 2024

The microfluidic measurement of capillary flow can be used to evaluate the response of biological samples to stimulation, where distance and velocity are altered. Melt-extruded multi-bored microfluidic capillaries allow for high-throughput testing wi...

  • Article
  • Open Access
3 Citations
2,549 Views
20 Pages

17 December 2022

The development of active, selective, and stable multicrystalline catalytic coatings on the inner surface of microcapillary reactors addresses environmental problems of fine organic synthesis, in particular by reducing the large quantities of reagent...

  • Article
  • Open Access
4 Citations
3,084 Views
18 Pages

In Situ Agarose Microfabrication Technology Using Joule Heating of Micro Ionic Current for On-Chip Cell Network Analysis

  • Kenji Shimoda,
  • Haruki Watanabe,
  • Yoshitsune Hondo,
  • Mitsuru Sentoku,
  • Kazufumi Sakamoto and
  • Kenji Yasuda

25 January 2022

Agarose microfabrication technology is one of the micropatterning techniques of cells having advantages of simple and flexible real-time fabrication of three-dimensional confinement microstructures even during cell cultivation. However, the conventio...

  • Proceeding Paper
  • Open Access
1 Citations
1,470 Views
5 Pages

1 November 2021

In this work, we present a micro-opto-fluidic platform for the analytical testing of alcoholic solutions (isopropyl alcohol, also known as isopropanol, and ethylene glycol) based on their absorption properties in the wavelength region 1.0–1.7 &...

  • Article
  • Open Access
3 Citations
1,897 Views
21 Pages

30 July 2025

This study aims to determine the optimal low-temperature stress relieving heat treatment that minimizes residual stresses while preserving corrosion resistance in Laser Powder Bed Fusion (L-PBF) processed Ti6Al4V alloy. Specifically, it investigates...

  • Article
  • Open Access
1 Citations
2,838 Views
12 Pages

Endosymbiosis between heterotrophic host and microalga often breaks down because of environmental conditions, such as temperature change and exposure to toxic substances. By the time of the apparent breakdown of endosymbiosis, it is often too late fo...

  • Article
  • Open Access
11 Citations
14,934 Views
14 Pages

Dependence of Impedance of Embedded Single Cells on Cellular Behaviour

  • Sungbo Cho,
  • Marc Castellarnau,
  • Josep Samitier and
  • Hagen Thielecke

21 February 2008

Non-invasive single cell analyses are increasingly required for the medicaldiagnostics of test substances or the development of drugs and therapies on the single celllevel. For the non-invasive characterisation of cells, impedance spectroscopy whichp...

  • Article
  • Open Access
31 Citations
9,590 Views
20 Pages

Effect of Strain Localization on Pitting Corrosion of an AlMgSi0.5 Alloy

  • Daniela Nickel,
  • Dagmar Dietrich,
  • Thomas Mehner,
  • Philipp Frint,
  • Dagobert Spieler and
  • Thomas Lampke

3 February 2015

The corrosion susceptibility of an age-hardened aluminum alloy in different processing conditions, especially after a single pass of equal-channel angular pressing (ECAP), is examined. The main question addressed is how corrosive attack is changed by...

  • Article
  • Open Access
2 Citations
3,204 Views
11 Pages

8 January 2022

Ethylene glycol (EG) and isopropanol (ISO) are among the major toxic alcohols that pose a risk to human health. However, it is important to distinguish them, since EG is more prone to cause renal failure, and can thus be more dangerous when ingested...

  • Article
  • Open Access
6 Citations
2,773 Views
17 Pages

3 April 2023

Blood elasticity is quantified using a single compliance model by analyzing pulsatile blood flow. However, one compliance coefficient is influenced substantially by the microfluidic system (i.e., soft microfluidic channels and flexible tubing). The n...

  • Feature Paper
  • Article
  • Open Access
1 Citations
3,090 Views
29 Pages

Non-Invasive Manipulation of Two-Phase Liquid–Liquid Slug Flow Parameters Using Magnetofluidics

  • Anoj Winston Gladius,
  • Simon Höving,
  • Mehdy Mendelawi,
  • Harikrishna Sreekumar Sheeba and
  • David W. Agar

26 November 2021

Liquid–liquid slug flow in a microcapillary, with its improved heat and mass transfer properties and narrow residence time, plays a vital role in process intensification. Knowledge of the flow properties in microchannels along variables’ controllabil...

  • Article
  • Open Access
1,113 Views
15 Pages

21 May 2024

In inertial confinement fusion, the sub-atmospheric purging through microcapillaries is of great importance to the high gas purity inside the cryogenic target and the low failure rate of experiments. In this study, a non-continuous flow model is deve...

  • Proceeding Paper
  • Open Access
2,331 Views
4 Pages

Silicon-Quartz Microcapillary Opto-Fluidic Platform Obtained by CMOS-Compatible Die to Wafer 200 mm Dual Bonding Process

  • Giuseppe Fiorentino,
  • Ben Jones,
  • Sophie Roth,
  • Edith Grac,
  • Murali Jayapala,
  • Pieter Bex,
  • Daniel D. De Almeida,
  • Aurelie Humbert and
  • Simone Severi

13 November 2018

A composite, capillary-driven microfluidic system suitable for transmitted light microscopy of cells (e.g., red and white human blood cells) is fabricated and demonstrated. The microfluidic system consists of a microchannels network fabricated in a p...

  • Article
  • Open Access
3 Citations
3,473 Views
9 Pages

Microcapillary Reactors via Coaxial Electrospinning: Fabrication of Small Poly(Acrylic Acid) Gel Beads and Thin Threads of Biological Cell Dimensions

  • Susan K. Kozawa,
  • Audrey Lord,
  • Jonah J. Scott-McKean,
  • Anne Y. Walker,
  • Alberto C. S. Costa and
  • Gary E. Wnek

30 March 2021

Poly(acrylic acid) (PAA) bulk gels and threads, typically derived via free-radical polymerization, are of interest as anionic polyelectrolyte mimics of cellular cytosol and as models for early protocells. The thread dimensions have been limited by th...

  • Communication
  • Open Access
11 Citations
4,334 Views
8 Pages

Nanomechanical Molecular Mass Sensing Using Suspended Microchannel Resonators

  • Alberto Martín-Pérez,
  • Daniel Ramos,
  • Javier Tamayo and
  • Montserrat Calleja

11 May 2021

In this work we study the different phenomena taking place when a hydrostatic pressure is applied in the inner fluid of a suspended microchannel resonator. Additionally to pressure-induced stiffness terms, we have theoretically predicted and experime...

  • Proceeding Paper
  • Open Access
477 Views
7 Pages

Liver cancer is one of the most common and lethal malignant tumors worldwide, of which hepatocellular carcinoma (HCC) accounts for 80%. In the process of forming liver cancer, cancer cell metastasis is the only path. First, cancer cells need to adher...

  • Article
  • Open Access
3,408 Views
9 Pages

Controllable Liquid Crystal Micro Tube Laser

  • Jia-De Lin,
  • Po-Chen Wu,
  • Ting-Shan Mo,
  • Bing-Yau Huang,
  • Chie-Tong Kuo and
  • Chia-Rong Lee

3 December 2021

This study demonstrates controllable random lasing emissions in a dye-doped nematic liquid crystal (DDNLC)-infiltrated microcapillary. The emission wavelength of the micro tube laser can be adjusted by changing the focusing position of the pumped pul...

  • Article
  • Open Access
11 Citations
4,069 Views
11 Pages

Microfluidic Characterization of Red Blood Cells Microcirculation under Oxidative Stress

  • Nadezhda A. Besedina,
  • Elisaveta A. Skverchinskaya,
  • Alexander S. Ivanov,
  • Konstantin P. Kotlyar,
  • Ivan A. Morozov,
  • Nikita A. Filatov,
  • Igor V. Mindukshev and
  • Anton S. Bukatin

16 December 2021

Microcirculation is one of the basic functional processes where the main gas exchange between red blood cells (RBCs) and surrounding tissues occurs. It is greatly influenced by the shape and deformability of RBCs, which can be affected by oxidative s...

  • Article
  • Open Access
2,253 Views
10 Pages

3 March 2021

The lateral migration of elastic capsules towards a microchannel centerline plays a major role in industrial and physiological processes. Via our computational investigation, we show that a constriction connecting two straight microchannels facilitat...

  • Technical Note
  • Open Access
5 Citations
3,000 Views
13 Pages

High-Throughput Tear Proteomics via In-Capillary Digestion for Biomarker Discovery

  • James Xiao,
  • Kyla Frenia,
  • Kathleen C. Garwood,
  • Jeremy Kimmel and
  • Leanne T. Labriola

14 November 2024

Tear fluid has emerged as a valuable resource for biomarker discovery; however, the limited sample volume, the dynamic composition, and the variability introduced by collection methods all present significant challenges to the analysis and interpreta...

  • Feature Paper
  • Article
  • Open Access
6 Citations
4,885 Views
10 Pages

14 November 2022

Antibiotic susceptibility testing is vital to tackle the emergence and spread of antimicrobial resistance. Inexpensive digital CMOS cameras can be converted into portable digital microscopes using 3D printed x-y-z stages. Microscopic examination of b...

  • Communication
  • Open Access
9 Citations
4,111 Views
14 Pages

28 May 2021

For the laser treatment of vascular dermatosis, the blood vessel morphology and depth in skin tissue is essential to achieve personalized intelligent therapy. The morphology can be obtained from the laser speckle imaging, and vessel depth was extract...

  • Communication
  • Open Access
6 Citations
2,936 Views
12 Pages

High-Sensitivity Liquid Dielectric Characterization Differential Sensor by 1-Bit Coding DGS

  • Bingfang Xie,
  • Zhiqiang Gao,
  • Cong Wang,
  • Luqman Ali,
  • Azeem Muhammad,
  • Fanyi Meng,
  • Cheng Qian,
  • Xumin Ding,
  • Kishor Kumar Adhikari and
  • Qun Wu

29 December 2022

This paper presents two devices to detect the liquid dielectric characterization. The differential method was used to enhance the robustness and reduce tolerance. A basic sensor based on defected ground structure (DGS) was designed and the optimizati...

  • Article
  • Open Access
3,002 Views
12 Pages

25 March 2021

Migration of an encapsulated leukemia HL60 cell through sudden contractions in a capillary tube is investigated. An HL60 cell is initially encapsulated in a viscoelastic shell fluid. As the cell-laden droplet moves through the sudden contraction, she...

  • Opinion
  • Open Access
10 Citations
18,567 Views
18 Pages

Possible Role of Fibrinaloid Microclots in Postural Orthostatic Tachycardia Syndrome (POTS): Focus on Long COVID

  • Douglas B. Kell,
  • Muhammed Asad Khan,
  • Binita Kane,
  • Gregory Y. H. Lip and
  • Etheresia Pretorius

31 January 2024

Postural orthostatic tachycardia syndrome (POTS) is a common accompaniment of a variety of chronic, inflammatory diseases, including long COVID, as are small, insoluble, ‘fibrinaloid’ microclots. We here develop the argument, with accompa...

  • Article
  • Open Access
10 Citations
4,648 Views
11 Pages

Cytokinesis D is Mediated by Cortical Flow of Dividing Cells Instead of Chemotaxis

  • Yuki Tanaka,
  • Md. Golam Sarowar Jahan,
  • Tomo Kondo,
  • Masaki Nakano and
  • Shigehiko Yumura

17 May 2019

Cytokinesis D is known as the midwife mechanism in which neighboring cells facilitate cell division by crossing the cleavage furrow of dividing cells. Cytokinesis D is thought to be mediated by chemotaxis, where midwife cells migrate toward dividing...

  • Brief Report
  • Open Access
1,541 Views
11 Pages

Relationships between CD34-, CD105- and bcl-2-Expression Levels and Contrast-Enhanced Ultrasound-Based Differential Diagnosis of Adnexal Tumours

  • Marek Szymanski,
  • Iwona Florczyk,
  • Radoslaw Janicki,
  • Piotr Bernard,
  • Piotr Domaracki,
  • Lukasz Brycht,
  • Robert Szyca,
  • Angelika Szymanska and
  • Julia Paniutycz

28 November 2023

The relationships between CEUS parameters of adnexal tumours and postoperative immunohistochemical assessments of CD34, CD105 and bcl-2 were analysed. This study aimed to investigate whether contrast-enhanced ultrasonography (CEUS) parameters depend...

  • Proceeding Paper
  • Open Access
1,638 Views
6 Pages

A Preliminary Investigation on Human Tears by Means of Surface Enhanced Raman Spectroscopy

  • Carlo Camerlingo,
  • Mikhail Lisitskiy,
  • Maria Lepore,
  • Marianna Portaccio,
  • Daniela Montorio,
  • Salvatore Del Prete and
  • Gilda Cennamo

14 November 2018

A preliminary investigation on human tears by Surface Enhanced Raman Spectroscopy (SERS) is reported. This study is aimed to test the feasibility of SERS for sensing tear composition and potential changes in their composition due to pathologies, eye...

  • Article
  • Open Access
760 Views
14 Pages

Nectar in Plant Species Fragaria vesca L.

  • Katja Malovrh,
  • Jože Bavcon,
  • Mitja Križman and
  • Blanka Ravnjak

22 September 2025

Fragaria vesca L. is a common plant species in Slovenia. It flowers from May to July. Our study was conducted throughout the 2024 season in two locations at which we sampled nectar in F. vesca flowers. To take the nectar samples, we used microcapilla...

  • Article
  • Open Access
14 Citations
5,329 Views
22 Pages

16 February 2022

Fibroblast cell migration plays a crucial role in the wound-healing process. Hence, its quantitative investigation is important to understand the mechanism of the wound-healing process. The dynamic nature of the wound-healing process can be easily im...

  • Article
  • Open Access
4 Citations
4,907 Views
12 Pages

Margination of Fluorescent Polylactic Acid–Polyaspartamide based Nanoparticles in Microcapillaries In Vitro: the Effect of Hematocrit and Pressure

  • Emanuela Fabiola Craparo,
  • Rosa D’Apolito,
  • Gaetano Giammona,
  • Gennara Cavallaro and
  • Giovanna Tomaiuolo

28 October 2017

The last decade has seen the emergence of vascular-targeted drug delivery systems as a promising approach for the treatment of many diseases, such as cardiovascular diseases and cancer. In this field, one of the major challenges is carrier marginatio...

  • Article
  • Open Access
2,095 Views
13 Pages

The greatest challenges of modern pharmacology are the design of drugs with the highest possible efficacy of an active substance and with the lowest possible invasiveness for the whole organism. A good solution features the application of a bioactive...

  • Article
  • Open Access
12 Citations
3,693 Views
17 Pages

Floral nectar is mainly a reward in the form of food for pollinators. Its composition plays an important role when pollinators choose their food. Several studies have shown that the popularity of flowers with nectar is influenced by the concentration...

  • Article
  • Open Access
19 Citations
2,516 Views
21 Pages

16 March 2024

Ground Granulated Blast-Furnace Slag (GGBS) and silica fume (SF) are frequently utilized in gel materials to produce environmentally sustainable concrete. The blend of the two components contributes to an enhancement in the pore structure, which, in...

  • Article
  • Open Access
22 Citations
5,270 Views
15 Pages

5 September 2019

Bone is based on an elaborate system of mineralization and vascularization. In hard tissue engineering, diverse biomaterials compatible with osteogenesis and angiogenesis have been developed. In the present study, to examine the processes of osteogen...

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