Vulnerability detection in software source code is crucial in ensuring software security. Existing models face challenges with dataset class imbalance and long training times. To address these issues, this paper introduces a multi-feature screening a...
Methods for the pairwise comparison of 2D and 3D molecular structures are established approaches in virtual screening. In this work, we explored three strategies for maximizing the virtual screening performance of these methods: (i) the merging of hi...
Background/Objectives: Artificial intelligence (AI) is increasingly applied in breast imaging, with potential to improve diagnostic accuracy and reduce workload in mammographic breast cancer screening. However, real-world integration of AI into natio...
Bullet screen, a form of online video commentary in emerging social media, is widely used on video websites frequented by young people. It has become a novel means of expressing emotions towards videos. The characteristics, such as varying text lengt...
Inhibition of key metabolic enzymes linked to type-2-diabetes (T2D) by food-derived compounds is a preventive emerging strategy in the management of T2D. Here, the impact of Parmigiano-Reggiano (PR) cheese peptide fractions, at four different ripenin...
Electrostatic interactions drive biomolecular interactions and associations. Computational modeling of electrostatics in biomolecular systems, such as protein-ligand, protein–protein, and protein-DNA, has provided atomistic insights into the bi...
The high-throughput screening and drug discovery paradigm has necessitated a change in preparation of natural product samples for screening programs. In an attempt to improve the quality of marine natural products samples for screening, several fract...
Human–computer interaction (HCI) with screens through gestures is a pivotal method amidst the digitalization trend. In this work, a gesture recognition method is proposed that combines multi-band spectral features with spatial characteristics o...
Globally, colorectal cancer is the third most diagnosed malignancy. It causes significant mortality and morbidity, which can be reduced by early diagnosis with an effective screening test. Integrating artificial intelligence (AI) and computer-aided d...
Vibrating flip-flow screens are widely employed in the deep screening processes of coal washing, solid waste treatment, metallurgy, and other fields, playing a crucial role in enhancing product quality and production efficiency. The screen surface an...
Background: Recent advancements in Artificial Intelligence (AI) have the potential to address the challenges of mammographic screening programs by enhancing the performance of Computer-Aided Detection (CAD) systems, improving detection accuracy, and...
Introduction: Social workers play a critical role in healthcare settings by addressing both medical and nonmedical needs. Trained in human behavior and social environments, they are best suited to screen for social determinants of health (SDOH) and c...
21 July 2022
Background: Delayed detection and diagnosis of Alzheimer’s Disease and related dementia (ADRD) can lead to suboptimal care and socioeconomic burdens on individuals, families, and communities. Our objective is to investigate dementia screening b...
Background: Pre-eclampsia (PE) remains a leading cause of maternal and perinatal morbidity and mortality worldwide. Early detection and risk stratification are critical for improving pregnancy outcomes. This review aims to summarize current advanceme...
Background: Children and youth often have challenges processing and integrating sensory information. These increasingly common challenges and can significantly impact development, learning, behavior, well-being, and participation in everyday activiti...
Manufacturing companies using CPSS integrate multiple data in organizational production and present the data in the form of data visualization with the help of a big screen data visualization. In order to help the manufacturing enterprises using the...
Pterocephalus hookeri, as a kind of popular traditional Tibetan medicine, is reputed to treat inflammatory related diseases. In the present work, a cyclooxygenase-2 functionalized affinity solid-phase extraction HPLC system was developed and combined...
(1) Background: The global burden of leprosy is not shared equally; with the majority of cases being diagnosed in Brazil, India, and Indonesia. Understanding the methods of active case detection (ACD) used in high and low endemic regions is vital for...
Developmental and adult/ageing neurotoxicity is an area needing alternative methods for chemical risk assessment. The formulation of a strategy to screen large numbers of chemicals is highly relevant due to potential exposure to compounds that may ha...
Marine geological carbon sequestration (GCS) is crucial for achieving carbon neutrality, with site geological safety being paramount. To address the high cost of extensive multi-channel seismic (MCS) surveys during the early site screening stage, esp...
Cervical cancer, primarily caused by high-risk human papillomavirus (HR-HPV) types 16 and 18, is a major global health concern. Persistent HR-HPV infection can progress from reversible precancerous lesions to invasive cervical cancer, which is driven...
HPV-related head and neck cancers are increasing globally and although they constitute a major public health problem, there are currently no validated screening or early detection methods in widespread clinical use. This review discusses advances in...
In recent years, risk stratification has sparked interest as an innovative approach to disease screening and prevention. The approach effectively personalizes individual risk, opening the way to screening and prevention interventions that are adapted...
Today’s power systems are operated closer to their stability limits due to the continuously growing load demands, interface to open markets, and integration of more renewable energies. In order to provide operators with clear insight on the cur...
1 December 2022
Background: Integration of diabetes mellitus screening in home visits for contact tracing for tuberculosis could identify hidden patients with either tuberculosis or diabetes mellitus. However, poor compliance to the first home screening has been rep...
The early diagnosis and treatment of civilizational diseases remain a significant challenge worldwide. Although advances in medical technology have led to the introduction of more screening options over time, these measures are still insufficient to...
Introduction: Of women in Canada diagnosed with invasive cervical cancer, 50% have not been screened according to guidelines. Interventions involving self-collected samples for human papillomavirus (hpv) screening could be an avenue to increase uptak...
Lung adenocarcinoma (LUAD) is characterized by substantial genetic heterogeneity, making it challenging to identify reliable biomarkers for diagnosis and treatment. Tumor mutational burden (TMB) is widely recognized as a predictive biomarker due to i...
Background/Objectives: Frailty screening is crucial for identifying vulnerable older adults who may benefit from interventions. However, the implementation of screening in primary care and integration into personalised care pathways remains limited....
The scientific selection of a third-party reverse logistics service provider (3PRLP) is helpful for enterprises to obtain the expected ecological and economic benefits. Different enterprises have different requirements for 3PRLP selection and, thus,...
Recent advances in deep learning have enhanced medical imaging research. Breast cancer is the most prevalent cancer among women, and many applications have been developed to improve its early detection. The purpose of this review is to examine how va...
Digital camera-based neutron imaging systems consisting of a neutron scintillator screen optically coupled to a digital camera are the most common digital neutron imaging system used in the neutron imaging community and are available at any state-of-...
21 October 2025
Background: Lung cancer is a major cause of death. Japan has a higher rate of early detection of lung cancer, which is attributed to the impact of chest X-ray examinations implemented as mass screening. This study describes the characteristics and ou...
Screening solid-phase combinatorial libraries of bioactive compounds against fluorescently labeled target biomolecules is an established technology in ligand and drug discovery. Rarely, however, do screening methods include comprehensive strategies&m...
Thrombin, a key enzyme of the serine protease superfamily, plays an integral role in the blood coagulation cascade and thrombotic diseases. In view of this, it is worthwhile to establish a method to screen thrombin inhibitors (such as natural flavono...
6 September 2022
(1) Objectives: Cumulative impacts refer to the legacies of land use decisions on environmental, community and health values. New integrative impact assessment tools are required to assess cumulative impacts on diverse values to meet sustainability g...
The aim of this study was to devise a methodology for the on-site evaluation of the potential presence of persistent organic pollutants (POPs) in incoming waste materials. A novel approach to POP screening was developed, integrating an excitation&nda...
The USEPA (United States Environmental Protection Agency) Storm Water Management Model (SWMM) is one of the most extensively implemented numerical models for simulating urban runoff. Parameter optimization is essential for reliable SWMM model simulat...
Current lung cancer screening guidelines in the United States fail to identify many individuals at risk of developing the disease. Additionally, existing healthcare infrastructure has been leveraged to establish IPN clinics, a promising approach to a...
Diatoms are critical indicators in marine paleoecology and contemporary ecosystem studies, yet the accuracy of diatom analysis depends on effective purification methods. Current screening and purification techniques often yield low accuracy. This stu...
This review evaluates the advances in the early detection and diagnosis of endometrial cancer (EC), emphasizing the growing importance of minimally invasive techniques and novel biomarkers. Current diagnostic protocols for EC rely heavily on invasive...
A multi-layered interference mitigation approach can significantly improve the performance of Global Navigation Satellite System (GNSS) receivers in the presence of jamming. In this work, three levels of defence are considered including: pre-correlat...
Aiming at the problems of intense subjectivity and high redundancy in the screening of indicators in the stability evaluation of loess slopes, this study proposes an evaluation method integrating the validity and reliability coefficients. Following a...
In order to integrate various operation information and accurately explore the operation situation of a power system, a dynamic comprehensive evaluation method considering index screening is proposed, and based on this, a situation awareness (SA) sys...
Background: Congenital hearing loss affects 1–3 per 1000 newborns and requires early detection to prevent developmental delays. Although Thailand implements universal screening, fragmented data systems limit effectiveness. To address this, Chia...
Background: Despite the positive conclusions of several randomized controlled trials and the publication of national recommendations on colorectal cancer (crc) screening, uptake remained low. The inauguration of the National Colorectal Cancer Screeni...
Geological storage of carbon dioxide in faulted sedimentary basins requires suitability evaluation methods that can address uncertainty, indicator interaction, and limited data availability. This study develops an integrated evaluation framework that...
Background: Access to cancer screening services is crucial for early detection and improved survival rates, yet older adults in Saudi Arabia face significant barriers. Recent data from the Saudi Health Ministry indicate that cancer incidence in this...
Advancing our understanding of pancreatic toxicity and metabolic disorders caused by environmental exposures requires innovative approaches. The pancreas, a vital organ for glucose regulation, is increasingly recognized as a target of harm from envir...
Influenza is still a chronic global health threat, inducing a sustained search for effective antiviral therapeutics. Computational methods have played a pivotal role in developing small molecule therapeutics. In this study, we applied a combined in s...
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