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193,249 Results Found

  • Article
  • Open Access
10 Citations
8,680 Views
21 Pages

7 September 2021

To those who primarily associate the word “humane” with “humane society”, its connection to criminology might appear to be unrelated. The origins of “humane” and “humane society” are complex and primarily reflect an abiding interest in human and soci...

  • Article
  • Open Access
1 Citations
1,957 Views
14 Pages

8 July 2024

This essay focuses on the nexus of vulnerability and rights. It argues that in transforming vulnerability from a stigma that alienated women from their humanity to the signature of human dignity, women bridged the gap between the liberatory promise o...

  • Article
  • Open Access
7 Citations
10,553 Views
14 Pages

5 August 2020

Guinea pigs (Cavia porcellus) have been used in research since the 19th century to collect data due to their physiological similarities to humans. Today, animals perform a vital role in experiments and concerns for laboratory animal welfare are enshr...

  • Feature Paper
  • Article
  • Open Access
2 Citations
8,917 Views
14 Pages

8 October 2021

Students educated in the juvenile justice system face acute challenges such as lack of motivation and negative attitudes toward school. Schools in the system are expected to provide rigorous, Common Core-standards-aligned instruction. Humane educatio...

  • Article
  • Open Access
117 Citations
37,725 Views
15 Pages

Childhood Attachment to Pets: Associations between Pet Attachment, Attitudes to Animals, Compassion, and Humane Behaviour

  • Roxanne D. Hawkins,
  • Joanne M. Williams and
  • Scottish Society for the Prevention of Cruelty to Animals (Scottish SPCA)

Attachment to pets has an important role in children’s social, emotional, and cognitive development, mental health, well-being, and quality of life. This study examined associations between childhood attachment to pets and caring and friendship behav...

  • Article
  • Open Access
1 Citations
1,307 Views
20 Pages

Burrowing Behavior as Robust Parameter for Early Humane Endpoint Determination in Murine Models for Pancreatic Cancer

  • Jakob Brandstetter,
  • Lisa Hoffmann,
  • Ingo Koopmann,
  • Tim Schreiber,
  • Benjamin Schulz,
  • Stephan Patrick Rosshart,
  • Dietmar Zechner,
  • Brigitte Vollmar and
  • Simone Kumstel

28 April 2025

Due to late-stage diagnoses and limited treatment options, pancreatic cancer is predicted to be the second leading cause of cancer deaths by 2030. Many different murine models were developed over the past decades to test new therapies for this tumor...

  • Article
  • Open Access
3 Citations
1,839 Views
12 Pages

Humane Endpoints in Swiss Webster Mice Infected with Toxoplasma gondii RH Strain

  • Igor Falco Arruda,
  • Maria Regina Reis Amendoeira,
  • Thamires Francisco Bonifácio,
  • Clarissa Nascimento da Silveira Raso,
  • Hyago da Silva Medeiros Elidio,
  • Jhônata Willy Rocha Coelho,
  • Luiz Cesar Cavalcanti Pereira da Silva and
  • Isabele Barbieri dos Santos

29 April 2024

The highly virulent Toxoplasma gondii RH strain is maintained through successive passages in mice, but there is still a lack of studies that refine these procedures from a 3Rs perspective, where humanitarian ideals aim to minimize the stress, pain, o...

  • Article
  • Open Access
19 Citations
4,342 Views
23 Pages

19 March 2024

The modern business world is confronted with growing social and environmental issues, which pose a serious challenge to pursuing sustainable growth. Drawing from the natural resource base view and stakeholder theory, this study examines the effect of...

  • Article
  • Open Access
1 Citations
2,046 Views
14 Pages

30 May 2023

P. 3808 records a popular sermons ceremony, which was a Buddhist folk preaching event held in the Zhongxing Palace to celebrate the birthday of Emperor Mingzong of Later Tang. Through the analysis of this text, it is possible to conduct a more compre...

  • Article
  • Open Access
2 Citations
3,828 Views
18 Pages

Background: Management of challenging behaviour causes victimization and violates the human rights of service users in psychiatric and long-term settings for people having mental health issues and learning disabilities. The purpose of the research wa...

  • Review
  • Open Access
34 Citations
10,206 Views
17 Pages

7 January 2021

Humane alternatives to harmful educational animal use include ethically-sourced cadavers, models, mannequins, mechanical simulators, videos, computer and virtual reality simulations, and supervised clinical and surgical experiences. In many life and...

  • Feature Paper
  • Essay
  • Open Access
454 Citations
24,226 Views
10 Pages

30 September 2019

In 1959, the Universities Federation for Animal Welfare (UFAW) Scholars Russell & Burch published the Principles of Humane Experimental Technique in which they laid out the principles of the Three Rs. However, the Three Rs owed much to others. It...

  • Review
  • Open Access
38 Citations
8,755 Views
25 Pages

Is Wildlife Fertility Control Always Humane?

  • Jordan O. Hampton,
  • Timothy H. Hyndman,
  • Anne Barnes and
  • Teresa Collins

21 October 2015

Investigation of fertility control techniques to reduce reproductive rates in wildlife populations has been the source of much research. Techniques targeting wildlife fertility have been diverse. Most research into fertility control methods has focus...

  • Review
  • Open Access
48 Citations
17,710 Views
13 Pages

Humane Slaughter of Edible Decapod Crustaceans

  • Francesca Conte,
  • Eva Voslarova,
  • Vladimir Vecerek,
  • Robert William Elwood,
  • Paolo Coluccio,
  • Michela Pugliese and
  • Annamaria Passantino

11 April 2021

Vast numbers of crustaceans are produced by aquaculture and caught in fisheries to meet the increasing demand for seafood and freshwater crustaceans. Simultaneously, the public is increasingly concerned about current methods employed in their handlin...

  • Article
  • Open Access
10 Citations
7,347 Views
26 Pages

22 February 2023

Human-related issues have become a popular topic in maritime safety research, with an increasing number of relevant research articles being published annually. However, a persistent problem in this field is that three terms, namely “human eleme...

  • Article
  • Open Access
16 Citations
10,107 Views
12 Pages

29 June 2021

The ongoing COVID-19 pandemic has enhanced the impact of digitalisation as a driver of transformation and advancements across almost every aspect of human life. With the majority actively embracing smart technologies and their benefits, the journey o...

  • Article
  • Open Access
6 Citations
4,774 Views
19 Pages

13 May 2021

One of the challenging aspects of robotics research is to successfully establish a human-like behavioural control strategy for human–robot handover, since a robotic controller is further complicated by the dynamic nature of the human response. This p...

  • Review
  • Open Access
9 Citations
4,382 Views
12 Pages

4 January 2023

The increasingly central role of robotic agents in daily life requires effective human–robot interaction (HRI). For roboticists to optimize interaction design, it is crucial to understand the potential effects of robotic agents on human perform...

  • Review
  • Open Access
26 Citations
5,907 Views
17 Pages

17 November 2018

The evolution of infectious pathogens in humans proved to be a global health problem. Technological advancements over the last 50 years have allowed better means of identifying novel therapeutics to either prevent or combat these infectious diseases....

  • Article
  • Open Access
1 Citations
5,250 Views
15 Pages

22 May 2020

While some human rights theorists suggest that the universalistic project of human rights can be consistent only with an individualistic conception of dignity aligned with liberal regimes, there have also been some voices of discontent raised from Ch...

  • Article
  • Open Access
12 Citations
4,259 Views
14 Pages

Refinement of Animal Model of Colorectal Carcinogenesis through the Definition of Novel Humane Endpoints

  • Rita Silva-Reis,
  • Ana I. Faustino-Rocha,
  • Mariana Gonçalves,
  • Catarina Castro Ribeiro,
  • Tiago Ferreira,
  • Carla Ribeiro-Silva,
  • Lio Gonçalves,
  • Luís Antunes,
  • Carlos Venâncio and
  • Paula A. Oliveira
  • + 2 authors

1 April 2021

This study aimed to define appropriate humane endpoints (HEs) for an animal model of colorectal carcinogenesis (CRC). Twenty-nine male Wistar rats were divided into two control groups (CTRL1 and CTRL2) injected with ethylenediamine tetraacetic acid (...

  • Article
  • Open Access
26 Citations
16,562 Views
17 Pages

Open science refers to both the practices and norms of more open and transparent communication and research in scientific disciplines and the discourse on these practices and norms. There is no such discourse dedicated to the humanities. Though the h...

  • Article
  • Open Access
11 Citations
4,968 Views
16 Pages

Studying and Analyzing Humane Endpoints in the Fructose-Fed and Streptozotocin-Injected Rat Model of Diabetes

  • Rita Silva-Reis,
  • Ana I. Faustino-Rocha,
  • Jéssica Silva,
  • Abigaël Valada,
  • Tiago Azevedo,
  • Lara Anjos,
  • Lio Gonçalves,
  • Maria de Lurdes Pinto,
  • Rita Ferreira and
  • Paula A. Oliveira
  • + 2 authors

18 April 2023

This work aimed to define a humane endpoint scoring system able to objectively identify signs of animal suffering in a rat model of type 2 diabetes. Sprague-Dawley male rats were divided into control and induced group. The induced animals drink a 10%...

  • Review
  • Open Access
21 Citations
8,040 Views
24 Pages

What Affects Human Decision Making in Human–Robot Collaboration?: A Scoping Review

  • Yuan Liu,
  • Glenda Caldwell,
  • Markus Rittenbruch,
  • Müge Belek Fialho Teixeira,
  • Alan Burden and
  • Matthias Guertler

9 February 2024

The advent of Industry 4.0 has heralded advancements in Human–robot Collaboration (HRC), necessitating a deeper understanding of the factors influencing human decision making within this domain. This scoping review examines the breadth of resea...

  • Article
  • Open Access
33 Citations
6,295 Views
26 Pages

26 May 2021

Sustainable manufacturing plays a role in ensuring products’ economic characteristics and reducing energy and resource consumption by improving the well-being of human workers and communities and maintaining safety. Using robots is one way for manufa...

  • Article
  • Open Access
9 Citations
11,487 Views
38 Pages

The advent of Artificial Intelligence in the cockpit and the air traffic control centre in the coming decade could mark a step-change improvement in aviation safety, or else could usher in a flush of ‘AI-induced’ accidents. Given that con...

  • Article
  • Open Access
14 Citations
4,993 Views
17 Pages

Integrating Human Barriers in Human Reliability Analysis: A New Model for the Energy Sector

  • Dina Guglielmi,
  • Alessio Paolucci,
  • Valerio Cozzani,
  • Marco Giovanni Mariani,
  • Luca Pietrantoni and
  • Federico Fraboni

Human reliability analysis (HRA) is a major concern for organizations. While various tools, methods, and instruments have been developed by the scientific community to assess human error probability, few of them actually consider human factors impact...

  • Review
  • Open Access
23 Citations
7,111 Views
25 Pages

Industry 5 and the Human in Human-Centric Manufacturing

  • Kendra Briken,
  • Jed Moore,
  • Dora Scholarios,
  • Emily Rose and
  • Andrew Sherlock

14 July 2023

Industry 4 (I4) was a revolutionary new stage for technological progress in manufacturing which promised a new level of interconnectedness between a diverse range of technologies. Sensors, as a point technology, play an important role in these develo...

  • Article
  • Open Access
9 Citations
4,790 Views
12 Pages

Establishment of Human Leukocyte Antigen-Mismatched Immune Responses after Transplantation of Human Liver Bud in Humanized Mouse Models

  • Akihiro Mori,
  • Soichiro Murata,
  • Nao Tashiro,
  • Tomomi Tadokoro,
  • Satoshi Okamoto,
  • Ryo Otsuka,
  • Haruka Wada,
  • Tomoki Murata,
  • Takeshi Takahashi and
  • Hideki Taniguchi
  • + 1 author

23 February 2021

Humanized mouse models have contributed significantly to human immunology research. In transplant immunity, human immune cell responses to donor grafts have not been reproduced in a humanized animal model. To elicit human T-cell immune responses, we...

  • Article
  • Open Access
9 Citations
2,841 Views
13 Pages

The emergence and recent development of collaborative robots have introduced a safer and more efficient human–robot collaboration (HRC) manufacturing environment. Since the release of COBOTs, a great amount of research efforts have been focused...

  • Review
  • Open Access
55 Citations
21,069 Views
17 Pages

Environmental Management, Human Resource Management and Green Human Resource Management: A Literature Review

  • José F. Molina-Azorin,
  • Maria D. López-Gamero,
  • Juan José Tarí,
  • Jorge Pereira-Moliner and
  • Eva M. Pertusa-Ortega

The main purpose of this paper is to integrate the literature on human resource management (HRM) and environmental management. Moreover, the paper shows the role that green human resource management (GHRM) plays in environmental management activities...

  • Review
  • Open Access
30 Citations
8,133 Views
17 Pages

Human Oncogenic Viruses: Characteristics and Prevention Strategies—Lessons Learned from Human Papillomaviruses

  • Luisa Galati,
  • Maria Vincenza Chiantore,
  • Mariarosaria Marinaro and
  • Paola Di Bonito

8 March 2024

Approximately 12% of human cancers worldwide are associated with infectious agents, which are classified by the International Agency for Research on Cancer (IARC) as Group 1 within the agents that are carcinogenic to humans. Most of these agents are...

  • Article
  • Open Access
9 Citations
3,860 Views
20 Pages

Beyond Human Detection: A Benchmark for Detecting Common Human Posture

  • Yongxin Li,
  • You Wu,
  • Xiaoting Chen,
  • Han Chen,
  • Depeng Kong,
  • Haihua Tang and
  • Shuiwang Li

24 September 2023

Human detection is the task of locating all instances of human beings present in an image, which has a wide range of applications across various fields, including search and rescue, surveillance, and autonomous driving. The rapid advancement of compu...

  • Proceeding Paper
  • Open Access
2,431 Views
4 Pages

The essentialist view of human nature holds that there is an a priori, non-historical essence to humanity, which is increasingly under the threat of rapidly developing technologies, especially human enhancement technologies. In contrast, the construc...

  • Review
  • Open Access
17 Citations
6,785 Views
33 Pages

24 August 2023

As the global population rapidly ages with longer life expectancy and declining birth rates, the need for healthcare services and caregivers for older adults is increasing. Current research envisions addressing this shortage by introducing domestic s...

  • Review
  • Open Access
8 Citations
5,928 Views
17 Pages

4 September 2024

The development of effective vaccines against infectious diseases remains a critical challenge in global health. Animal models play a crucial role in vaccine development by providing valuable insights into the efficacy, safety, and mechanisms of immu...

  • Article
  • Open Access
1 Citations
1,597 Views
17 Pages

HumanEnerg Hotspot: Conceptual Design of an Agile Toolkit for Human Energy Reinforcement in Industry 5.0

  • Ifeoma Chukwunonso Onyemelukwe,
  • José Antonio Vasconcelos Ferreira,
  • Ana Luísa Ramos and
  • Inês Direito

18 September 2024

This paper presents the conceptual design of the HumanEnerg Hotspot, an agile toolkit aimed at addressing the human energy crisis in the context of Industry 5.0. The toolkit has been developed using a blend of Design Science Research (DSR) and Human-...

  • Review
  • Open Access
30 Citations
8,638 Views
28 Pages

27 December 2024

Human-centricity, a cornerstone of Industry 5.0, emphasizes the central role of human needs and capabilities in the technological landscape of modern manufacturing. As Digital Twins (DTs) become a core technology of Industry 4.0, the evolution toward...

  • Proceeding Paper
  • Open Access
2,714 Views
4 Pages

When we enter intelligent society, we need to rethink about the topic of human essence. As we know, human beings have no absolute, fixed essence. The essence of human beings is the combination of an innate substrate and acquired creation. As the degr...

  • Article
  • Open Access
5 Citations
2,592 Views
12 Pages

Body Temperature Drop as a Humane Endpoint in Snake Venom-Lethality Neutralization Tests

  • Rosa De Jesus,
  • Adam E. Tratner,
  • Alanna Madrid,
  • Andrés Rivera-Mondragón,
  • Goy E. Navas,
  • Ricardo Lleonart,
  • Gabrielle B. Britton and
  • Patricia L. Fernández

26 August 2023

Snake venom neutralization potency tests are required for quality control assessment by manufacturers and regulatory authorities. These assays require the use of large numbers of mice that manifest severe signs associated with pain and distress and l...

  • Feature Paper
  • Article
  • Open Access
11 Citations
4,707 Views
21 Pages

From Human-Human to Human-Machine Cooperation in Manufacturing 4.0

  • Lydia Habib,
  • Marie-Pierre Pacaux-Lemoine,
  • Quentin Berdal and
  • Damien Trentesaux

26 October 2021

Humans are currently experiencing the fourth industrial revolution called Industry 4.0. This revolution came about with the arrival of new technologies that promise to change the way humans work and interact with each other and with machines. It aims...

  • Concept Paper
  • Open Access
3 Citations
6,145 Views
18 Pages

3 April 2024

Modern slavery and human trafficking are well recognized as significant problems in need of legislation, policies, and actions from a wide range of stakeholders in the United Kingdom. The passage of the UK Modern Slavery Act 2015 is a hallmark of the...

  • Review
  • Open Access
66 Citations
10,688 Views
20 Pages

Learning and Comfort in Human–Robot Interaction: A Review

  • Weitian Wang,
  • Yi Chen,
  • Rui Li and
  • Yunyi Jia

28 November 2019

Collaborative robots provide prospective and great solutions to human–robot cooperative tasks. In this paper, we present a comprehensive review for two significant topics in human–robot interaction: robots learning from demonstrations and...

  • Systematic Review
  • Open Access
12 Citations
6,024 Views
22 Pages

Trust and Trustworthiness from Human-Centered Perspective in Human–Robot Interaction (HRI)—A Systematic Literature Review

  • Debora Firmino de Souza,
  • Sonia Sousa,
  • Kadri Kristjuhan-Ling,
  • Olga Dunajeva,
  • Mare Roosileht,
  • Avar Pentel,
  • Mati Mõttus,
  • Mustafa Can Özdemir and
  • Žanna Gratšjova

The transition from Industry 4.0 to Industry 5.0 highlights recent European efforts to design intelligent devices, systems, and automation that can work alongside human intelligence and enhance human capabilities. In this vision, human–machine...

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