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41,683 Results Found

  • Article
  • Open Access
37 Citations
43,285 Views
19 Pages

Fasting: How to Guide

  • Alda Attinà,
  • Claudia Leggeri,
  • Rita Paroni,
  • Francesca Pivari,
  • Michele Dei Cas,
  • Alessandra Mingione,
  • Maria Dri,
  • Marco Marchetti and
  • Laura Di Renzo

7 May 2021

Fasting potentials are the most interesting topics in the Nutritional Era. Fasting consists of the catabolism of lipids, proteins, and carbohydrates to maintain blood glucose levels in a normal range. The action mechanisms of fasting were firstly und...

  • Review
  • Open Access
25 Citations
12,868 Views
33 Pages

How Far Are We from Prescribing Fasting as Anticancer Medicine?

  • Maria V. Deligiorgi,
  • Charis Liapi and
  • Dimitrios T. Trafalis

1 December 2020

(1) Background: the present review provides a comprehensive and up-to date overview of the potential exploitation of fasting as an anticancer strategy. The rationale for this concept is that fasting elicits a differential stress response in the setti...

  • Article
  • Open Access
7 Citations
5,792 Views
17 Pages

Does Ramadan Intermittent Fasting Affect the Fasting Blood Glucose Level among Type II Diabetic Patients?

  • Yazun Jarrar,
  • Ghasaq Abdul-Wahab,
  • Rami Mosleh,
  • Sara Abudahab,
  • Qais Jarrar,
  • Anas Hamdan,
  • Shurouq Ghalib Qadous,
  • Ruba Balasmeh,
  • Abdulqader Fadhil Abed and
  • Mohammed Ali AlShehri
  • + 2 authors

18 October 2023

Background: The level of fasting blood glucose (FBG) is influenced by several factors, including health status, genetics, and diet. Some studies have reported a beneficial effect of Ramadan Intermittent Fasting (RIF) on diabetic patients. However, cl...

  • Review
  • Open Access
36 Citations
23,112 Views
20 Pages

Traditional and Medical Applications of Fasting

  • Francesco Visioli,
  • Carla Mucignat-Caretta,
  • Francesca Anile and
  • Stefan-Alexandru Panaite

19 January 2022

Fasting has been practiced for millennia, for religious, ethical, or health reasons. It is also commonplace among different species, from humans, to animals, to lower eukaryotes. Research on fasting is gaining traction based on recent studies that sh...

  • Article
  • Open Access
2 Citations
4,259 Views
11 Pages

28 March 2023

Background: Hypertension (HBP) often occurs together with hypertriglyceridemia which indicates elevated triglyceride (TG) and remnant cholesterol (RC) levels. Non-fasting (i.e., postprandial) blood lipid test after a daily meal has been recommended b...

  • Perspective
  • Open Access
106 Citations
54,839 Views
11 Pages

18 April 2019

Intermittent fasting is increasing in popularity as a means of losing weight and controlling chronic illness. Patients with diabetes mellitus, both types 1 and 2, comprise about 10% of the population in the United States and would likely be attracted...

  • Review
  • Open Access
212 Citations
99,781 Views
15 Pages

Intermittent Fasting and Metabolic Health

  • Izzah Vasim,
  • Chaudry N. Majeed and
  • Mark D. DeBoer

31 January 2022

Given the ongoing strain that the obesity epidemic has placed on public health outcomes, new and effective approaches to weight control are needed. One approach to improving weight and metabolic outcomes is intermittent fasting, which consists of mul...

  • Review
  • Open Access
2 Citations
21,720 Views
26 Pages

20 June 2025

It is well established that different fasting strategies offer a range of benefits and may even serve as potential therapeutic approaches for metabolic diseases. The biological effects of intermittent fasting (IF) are multidimensional, involving the...

  • Article
  • Open Access
86 Citations
18,576 Views
11 Pages

The Impact of Intermittent Fasting (Ramadan Fasting) on Psoriatic Arthritis Disease Activity, Enthesitis, and Dactylitis: A Multicentre Study

  • Mohammad Adawi,
  • Giovanni Damiani,
  • Nicola Luigi Bragazzi,
  • Charlie Bridgewood,
  • Alessia Pacifico,
  • Rosalynn R. Z. Conic,
  • Aldo Morrone,
  • Piergiorgio Malagoli,
  • Paolo Daniele Maria Pigatto and
  • Abdulla Watad
  • + 2 authors

12 March 2019

Intermittent circadian fasting, namely Ramadan, is a common worldwide practice. Such fasting has a positive impact on psoriasis, but no data exist on its role in psoriatic arthritis (PsA)—a disease that is clearly linked to body mass index. We...

  • Article
  • Open Access
6 Citations
9,475 Views
22 Pages

7 September 2018

The article deals with the revival of fasting in Russia after a long period of its nearly full neglect. On the basis of electronic sources, such as web forums, question-and-answer services, streaming video channels, and other publications the author...

  • Review
  • Open Access
4 Citations
12,195 Views
11 Pages

19 November 2024

Intermittent fasting (IF), including alternate day fasting (ADF) and time-restricted feeding (TRF) or, in humans, time-restricted eating (TRE), has been associated with the prevention and improvement of diseases, including inflammatory bowel disease...

  • Review
  • Open Access
1,084 Views
20 Pages

Intermittent Fasting: A Metabolically Focused Therapeutic Strategy for Obesity

  • Natalia Diaz-Garrido,
  • Sebastián Zagmutt,
  • Alejandro Regaldiz,
  • Pedro Cisternas and
  • Marianela Bastías-Pérez

23 January 2026

The global prevalence of obesity continues to rise and is a significant risk factor for the onset and progression of cardiovascular diseases. Despite the development of new pharmacological therapies, novel strategies are being explored to mitigate th...

  • Review
  • Open Access
30 Citations
18,318 Views
12 Pages

Intermittent Fasting and Sleep: A Review of Human Trials

  • Mara McStay,
  • Kelsey Gabel,
  • Sofia Cienfuegos,
  • Mark Ezpeleta,
  • Shuhao Lin and
  • Krista A. Varady

1 October 2021

This review examines the effects of two popular intermittent fasting regimens on sleep in adults with overweight and obesity. Specifically, the effects of time restricted eating (TRE; eating all food within a 4–10 h window) and alternate day fasting...

  • Review
  • Open Access
205 Citations
92,831 Views
18 Pages

Intermittent Fasting in Cardiovascular Disorders—An Overview

  • Bartosz Malinowski,
  • Klaudia Zalewska,
  • Anna Węsierska,
  • Maya M. Sokołowska,
  • Maciej Socha,
  • Grzegorz Liczner,
  • Katarzyna Pawlak-Osińska and
  • Michał Wiciński

20 March 2019

Intermittent fasting is a form of time restricted eating (typically 16 h fasting and 8 h eating), which has gained popularity in recent years and shows promise as a possible new paradigm in the approach to weight loss and the reduction of inflammatio...

  • Review
  • Open Access
2,963 Views
18 Pages

24 December 2025

Background/Objectives: Prolonged fasting—defined as voluntary abstinence from caloric intake for periods exceeding 24 h—is increasingly recognized not only as a metabolic intervention but also as a psycho-behavioral modulator. According t...

  • Article
  • Open Access
4 Citations
2,835 Views
12 Pages

The Interplay between Metabolic Syndrome and Religious Fasting in Postmenopausal Women

  • Anna Kokkinopoulou,
  • Niki Katsiki,
  • Ioannis Pagkalos,
  • Nikolaos E. Rodopaios,
  • Alexandra-Aikaterini Koulouri,
  • Eleni Vasara,
  • Sousana K. Papadopoulou,
  • Petros Skepastianos,
  • Emmanouil Dermitzakis and
  • Anthony G. Kafatos
  • + 1 author

26 May 2023

Religious fasting that involves abstinence from specific food(s) is part of many religions worldwide and has been gaining attention by the research community during the last years. The study aimed to investigate whether the periodic Christian Orthodo...

  • Article
  • Open Access
5 Citations
3,766 Views
12 Pages

Effects of Fasting on THP1 Macrophage Metabolism and Inflammatory Profile

  • Julia Rius-Bonet,
  • Salvador Macip,
  • Marta Massip-Salcedo and
  • Daniel Closa

20 August 2024

Fasting can affect the body’s inflammatory response, and this has been linked to potential health benefits, including improvements for people with rheumatic diseases. In this work, we evaluated, in vitro, how changes in nutrient availability al...

  • Article
  • Open Access
1 Citations
3,356 Views
10 Pages

Therapeutic Fasting: Are Patients Aged 65 and Over Ready?

  • Baptiste Gramont,
  • Martin Killian,
  • Elodie Bernard,
  • Laure Martinez,
  • Sebastien Bruel,
  • Bogdan Galusca,
  • Nathalie Barth and
  • Thomas Célarier

10 May 2022

While being the main potential beneficiaries of therapeutic fasting’s health benefits, the elderly are frequently thought of as being too fragile to fast. The main objective of our survey was to review the knowledge, practices, and acceptabilit...

  • Review
  • Open Access
1 Citations
11,714 Views
14 Pages

Fasting and Diet: Overview in Chronic Lymphocytic Leukemia

  • Alessandra Trojani,
  • Luca Emanuele Bossi and
  • Roberto Cairoli

19 October 2024

Background: This review aims to provide an overview of the potential impact of fasting and diet on cancer, and in particular, on chronic lymphocytic leukemia (CLL), which is the most frequent form of leukemia in the Western world. Methods: Experiment...

  • Review
  • Open Access
27 Citations
17,932 Views
14 Pages

Efficacy of Fasting in Type 1 and Type 2 Diabetes Mellitus: A Narrative Review

  • Daniel Herz,
  • Sandra Haupt,
  • Rebecca Tanja Zimmer,
  • Nadine Bianca Wachsmuth,
  • Janis Schierbauer,
  • Paul Zimmermann,
  • Thomas Voit,
  • Ulrike Thurm,
  • Kayvan Khoramipour and
  • Othmar Moser
  • + 1 author

10 August 2023

Over the last decade, studies suggested that dietary behavior modification, including fasting, can improve metabolic and cardiovascular markers as well as body composition. Given the increasing prevalence of people with type 1 (T1DM) and type 2 diabe...

  • Systematic Review
  • Open Access
19 Citations
32,672 Views
28 Pages

The Effect of Intermittent Fasting on Appetite: A Systematic Review and Meta-Analysis

  • Rebecca L. Elsworth,
  • Angelica Monge,
  • Rachel Perry,
  • Elanor C. Hinton,
  • Annika N. Flynn,
  • Alex Whitmarsh,
  • Julian P. Hamilton-Shield,
  • Natalia S. Lawrence and
  • Jeffrey M. Brunstrom

1 June 2023

Previously, narrative reviews have considered the effects of intermittent fasting on appetite. One suggestion is that intermittent fasting attenuates an increase in appetite that typically accompanies weight loss. Here, we conducted the first systema...

  • Article
  • Open Access
2,939 Views
13 Pages

Non-Alcoholic Fatty Liver Disease Markers Associated with Fasting Serum Insulin and Urinary Albumin Excretion Independent of Fasting Plasma Glucose

  • Shuichi Katoh,
  • Markku Peltonen,
  • Mikio Zeniya,
  • Yoichi Sakamoto,
  • Kazunori Utsunomiya,
  • Rimei Nishimura and
  • Jaakko Tuomilehto

29 September 2020

Objective: We examined the association between non-alcoholic fatty liver disease (NAFLD) markers and fasting serum immunoreactive insulin (FIRI) and urinary albumin excretion (UAE). Subjects and methods: This study comprised Periods I and II from Jan...

  • Review
  • Open Access
121 Citations
37,446 Views
16 Pages

27 May 2019

Intermittent fasting (IF) has been gaining popularity as a means of losing weight. The Ramadan fast (RF) is a form of IF practiced by millions of adult Muslims globally for a whole lunar month every year. It entails a major shift from normal eating p...

  • Article
  • Open Access
7 Citations
2,958 Views
16 Pages

27 December 2023

The study of liquid biopsy with plasma samples is being conducted to identify biomarkers for clinical use. Exosomes, containing nucleic acids and metabolites, have emerged as possible sources for biomarkers. To evaluate the effectiveness of exosomes...

  • Review
  • Open Access
15 Citations
7,039 Views
15 Pages

Can Fasting Curb the Metabolic Syndrome Epidemic?

  • Josip Vrdoljak,
  • Marko Kumric,
  • Marino Vilovic,
  • Dinko Martinovic,
  • Veljko Rogosic,
  • Josip A. Borovac,
  • Tina Ticinovic Kurir and
  • Josko Bozic

20 January 2022

Metabolic syndrome (MetS) represents a cluster of metabolic abnormalities that includes hypertension, central obesity, insulin resistance, and atherogenic dyslipidemia. Due to the high prevalence (around 1/3 of the world population) economic burden o...

  • Article
  • Open Access
5 Citations
9,740 Views
12 Pages

Beyond Guidelines: The Persistent Challenge of Preoperative Fasting Times

  • Ricardo Euzebio Ribeiro Silva Júnior,
  • Camila A. Soriano,
  • Pablo Amercio Silva Lima,
  • Bruno Fernandes de Oliveira Santos,
  • Wesley Goncalves Nascimento Pereira,
  • Marcos Torres de Brito Filho,
  • Júlio Cezar Brandão and
  • Marcos Adriano Lessa

28 November 2023

Despite the advancements in evidence-based medicine, many hospitals still maintain high rates of patients undergoing prolonged preoperative fasting. The goal of this study is to determine the prevalence of prolonged fasting time among patients underg...

  • Review
  • Open Access
49 Citations
37,966 Views
23 Pages

Effects of Intermittent Fasting on Cardiometabolic Health: An Energy Metabolism Perspective

  • Manuel Dote-Montero,
  • Guillermo Sanchez-Delgado and
  • Eric Ravussin

23 January 2022

This review summarizes the effects of different types of intermittent fasting (IF) on human cardiometabolic health, with a focus on energy metabolism. First, we discuss the coordinated metabolic adaptations (energy expenditure, hormonal changes and m...

  • Article
  • Open Access
44 Citations
14,621 Views
11 Pages

Pilot Study of Novel Intermittent Fasting Effects on Metabolomic and Trimethylamine N-oxide Changes During 24-hour Water-Only Fasting in the FEELGOOD Trial

  • Rachel L. Washburn,
  • James E. Cox,
  • Joseph B. Muhlestein,
  • Heidi T. May,
  • John F. Carlquist,
  • Viet T. Le,
  • Jeffrey L. Anderson and
  • Benjamin D. Horne

23 January 2019

Intermittent fasting (IF) has been connected with health benefits such as weight loss, lower risk of coronary artery disease (CAD) and diabetes, increased longevity, and improved quality of life. However, the mechanisms of these IF benefits in humans...

  • Review
  • Open Access
8 Citations
9,792 Views
23 Pages

Fasting and Exercise in Oncology: Potential Synergism of Combined Interventions

  • Rebekah L. Wilson,
  • Dong-Woo Kang,
  • Cami N. Christopher,
  • Tracy E. Crane and
  • Christina M. Dieli-Conwright

28 September 2021

Nutrition and exercise interventions are strongly recommended for most cancer patients; however, much debate exists about the best prescription. Combining fasting with exercise is relatively untouched within the oncology setting. Separately, fasting...

  • Review
  • Open Access
11 Citations
7,309 Views
18 Pages

Is Fasting Good When One Is at Risk of Liver Cancer?

  • Iulia Minciuna,
  • Laurens A. van Kleef,
  • Horia Stefanescu and
  • Bogdan Procopet

17 October 2022

Hepatocellular carcinoma (HCC), one of the leading causes of cancer-related deaths worldwide, is a multistep process that usually develops in the background of cirrhosis, but also in a non-cirrhotic state in patients with non-alcoholic fatty liver di...

  • Review
  • Open Access
3 Citations
11,858 Views
12 Pages

13 November 2023

Despite the progress in treatment options and improved understanding of pathophysiology, type 2 diabetes remains one of the costliest and most harmful global chronic diseases. The current guidelines encourage physicians to fight an uphill battle and...

  • Review
  • Open Access
32 Citations
12,635 Views
13 Pages

3 November 2022

Intermittent fasting is a non-pharmacological dietary approach to management of obesity and metabolic syndrome, involving periodic intervals of complete or near-complete abstinence from food and energy-containing fluids. This dietary strategy has rec...

  • Case Report
  • Open Access
10 Citations
12,209 Views
8 Pages

Intermittent Fasting and Reduction of Inflammatory Response in a Patient with Ulcerative Colitis

  • Ángel Roco-Videla,
  • Claudio Villota-Arcos,
  • Carolina Pino-Astorga,
  • Daniela Mendoza-Puga,
  • Mauricio Bittner-Ortega and
  • Tatiana Corbeaux-Ascui

11 August 2023

Ulcerative colitis is an inflammatory disease that affects the colon, generating a crisis period associated with diarrhea and ulcerations. Stress plays a pivotal role in modulating the inflammatory response and aggravating progression. Different stud...

  • Review
  • Open Access
19 Citations
30,228 Views
14 Pages

Intermittent Fasting: Does It Affect Sports Performance? A Systematic Review

  • Javier Conde-Pipó,
  • Agustín Mora-Fernandez,
  • Manuel Martinez-Bebia,
  • Nuria Gimenez-Blasi,
  • Alejandro Lopez-Moro,
  • José Antonio Latorre,
  • Antonio Almendros-Ruiz,
  • Bernardo Requena and
  • Miguel Mariscal-Arcas

4 January 2024

Intermittent fasting is one of the most popular types of diet at the moment because it is an effective nutritional strategy in terms of weight loss. The main objective of this review is to analyze the effects that intermittent fasting has on sports p...

  • Article
  • Open Access
14 Citations
34,995 Views
14 Pages

Long-Term Fasting-Induced Ketosis in 1610 Subjects: Metabolic Regulation and Safety

  • Franziska Grundler,
  • Robin Mesnage,
  • Philip M. M. Ruppert,
  • Demetrios Kouretas and
  • Françoise Wilhelmi de Toledo

13 June 2024

Background: There is a growing consensus that fasting-induced ketosis has beneficial effects on human physiology. Despite these compelling benefits, fasting-induced ketosis raises concerns in some clinicians because it is often inappropriately compar...

  • Article
  • Open Access
7 Citations
8,358 Views
15 Pages

Examining Associations Between Fasting Behavior, Orthorexia Nervosa, and Eating Disorders

  • Przemysław Domaszewski,
  • Aleksandra M. Rogowska and
  • Kaja Żylak

11 December 2024

Background/Objectives: Fasting, orthorexia nervosa, and eating disorders are increasingly prevalent and interconnected. Understanding their relationship is essential for identifying potential risks and developing effective prevention and intervention...

  • Article
  • Open Access
41 Citations
13,973 Views
15 Pages

Influence of Long-Term Fasting on Blood Redox Status in Humans

  • Françoise Wilhelmi de Toledo,
  • Franziska Grundler,
  • Nikolaos Goutzourelas,
  • Fotios Tekos,
  • Eleni Vassi,
  • Robin Mesnage and
  • Demetrios Kouretas

Fasting is increasingly practiced to improve health and general well-being, as well as for its cytoprotective effects. Changes in blood redox status, linked to the development of a variety of metabolic diseases, have been recently documented during c...

  • Review
  • Open Access
37 Citations
15,490 Views
21 Pages

Intermittent and Periodic Fasting, Hormones, and Cancer Prevention

  • Giulia Salvadori,
  • Mario Giuseppe Mirisola and
  • Valter D. Longo

13 September 2021

The restriction of proteins, amino acids or sugars can have profound effects on the levels of hormones and factors including growth hormone, IGF-1 and insulin. In turn, these can regulate intracellular signaling pathways as well as cellular damage an...

  • Review
  • Open Access
40 Citations
22,778 Views
21 Pages

25 February 2022

Obesity has been an escalating worldwide health problem for decades, and it is likely a risk factor of prediabetes and diabetes. Correlated with obesity, the number of diabetic patients is also remarkable. A modest weight loss (5–10%) is critic...

  • Communication
  • Open Access
17 Citations
4,820 Views
9 Pages

Effects of Short Transport and Prolonged Fasting in Beef Calves

  • Viviana Bravo,
  • Carmen Gallo and
  • Gerardo Acosta-Jamett

3 October 2018

Marketing is a stressful process for beef calves, because they are removed from their environment, often weaned just before loading, loaded, transported, and unloaded. It also involves extended periods without food and water and mixing with unfamilia...

  • Article
  • Open Access
1 Citations
4,223 Views
15 Pages

Periodic Fasting and Acute Cardiac Events in Patients Evaluated for COVID-19: An Observational Prospective Cohort Study

  • Benjamin D. Horne,
  • Jeffrey L. Anderson,
  • Francois Haddad,
  • Heidi T. May,
  • Viet T. Le,
  • Stacey Knight,
  • Tami L. Bair and
  • Kirk U. Knowlton

28 June 2024

Background: Periodic fasting was previously associated with greater longevity and a lower incidence of heart failure (HF) in a pre-pandemic population. In patients with coronavirus disease 2019 (COVID-19), periodic fasting was associated with a lower...

  • Review
  • Open Access
4 Citations
16,797 Views
20 Pages

Fasting as an Adjuvant Therapy for Cancer: Mechanism of Action and Clinical Practice

  • Yichun Xie,
  • Huabin Ye,
  • Zhongjun Liu,
  • Zhiqing Liang,
  • Jinrong Zhu,
  • Rongxin Zhang and
  • Yan Li

12 November 2024

The fundamental biological characteristics of tumor cells are characterized by irregularities in signaling and metabolic pathways, which are evident through increased glucose uptake, altered mitochondrial function, and the ability to evade growth sig...

  • Article
  • Open Access
45 Citations
7,448 Views
14 Pages

The Safety and Impact of a Model of Intermittent, Time-Restricted Circadian Fasting (“Ramadan Fasting”) on Hidradenitis Suppurativa: Insights from a Multicenter, Observational, Cross-Over, Pilot, Exploratory Study

  • Giovanni Damiani,
  • Naim Mahroum,
  • Paolo Daniele Maria Pigatto,
  • Alessia Pacifico,
  • Piergiorgio Malagoli,
  • Danica Tiodorovic,
  • Rosalynn RZ Conic,
  • Howard Amital,
  • Nicola Luigi Bragazzi and
  • Mohammad Adawi
  • + 1 author

1 August 2019

Hidradenitis suppurativa (HS) is a chronic-relapsing and debilitating disease, which affects the components of the folliculopilosebaceous unit and severely impacts on the perceived health-related quality of life. Among the possible treatments, dietar...

  • Article
  • Open Access
13 Citations
16,667 Views
16 Pages

Effects of Fasting on the Physiological and Psychological Responses in Middle-Aged Men

  • Krzysztof Stec,
  • Karol Pilis,
  • Wiesław Pilis,
  • Paweł Dolibog,
  • Sławomir Letkiewicz and
  • Alicja Głębocka

3 August 2023

Tracking changes in the body during fasting takes into account indicators of mental well-being and physiological parameters. The aim of the study was to measure psychological and physiological reactions, along with their mutual relations, caused by 8...

  • Article
  • Open Access
2 Citations
1,832 Views
16 Pages

Measuring Changes in Upper Body Movement Due to Fasting Using a Camera

  • Longfei Chen,
  • Muhammad Ahmed Raza,
  • Imran Saied,
  • Tughrul Arslan and
  • Robert B. Fisher

13 November 2024

Understanding activity levels during fasting is important for promoting healthy fasting practices. While most existing studies focus on step counts to objectively assess the impact of fasting on activity levels and behavioral changes, the results hav...

  • Feature Paper
  • Article
  • Open Access
9 Citations
3,316 Views
16 Pages

Fasting-Induced Upregulation of MKP-1 Modulates the Hepatic Response to Feeding

  • Jacob Sellers,
  • Abigail Brooks,
  • Savanie Fernando,
  • Gabrielle Westenberger,
  • Sadie Junkins,
  • Shauri Smith,
  • Kisuk Min and
  • Ahmed Lawan

4 November 2021

The liver plays a key role in whole-body, glucose and lipid homeostasis. Nutritional signals in response to fasting and refeeding regulate hepatic lipid synthesis. It is established that activation of mitogen-activated protein kinase (MAPK) phosphata...

  • Review
  • Open Access
16 Citations
21,720 Views
44 Pages

Intermittent Fasting: Myths, Fakes and Truth on This Dietary Regimen Approach

  • Simone Brogi,
  • Rita Tabanelli,
  • Sara Puca and
  • Vincenzo Calderone

21 June 2024

Intermittent fasting (IF) has been indicated as a valuable alternative to the classical caloric restriction dietary regimen for lowering body weight and preventing obesity-related complications, such as metabolic syndrome and type II diabetes. Howeve...

  • Review
  • Open Access
2,397 Views
25 Pages

17 December 2025

Objectives: Intermittent fasting regimens that include periods of prolonged fasting may mimic certain well-documented benefits of calorie restriction. In this narrative review, we synthesize preclinical and human data on endocrine adaptations during...

  • Review
  • Open Access
25 Citations
12,182 Views
16 Pages

Short-Term Fasting Synergizes with Solid Cancer Therapy by Boosting Antitumor Immunity

  • Nadia de Gruil,
  • Hanno Pijl,
  • Sjoerd H. van der Burg and
  • Judith R. Kroep

9 March 2022

Short-term fasting (STF), using a low caloric, low protein fasting mimicking diet (FMD), appears to be a promising strategy to enhance chemotherapy-based cancer efficacy, while potentially alleviating toxicity. Preclinical results suggest that enhanc...

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