As an important component of the movement speed adjustment components of the executive elements in a hydraulic system, the speed-control valve should have good dynamic response ability and dynamic and static flow stability. In the working state, due...
Purinergic signaling is associated with a vast spectrum of physiological processes, including cardiovascular system function and, in particular, its pathological calcifications, such as aortic valve stenosis. Aortic valve stenosis (AS) is a degenerat...
The throughput of the pneumatic brake valve is a key parameter in ensuring fast and safe vehicle braking. The instantaneous value of this parameter determines the short response time of the system to an operator’s force. The scientific objectiv...
Background: Frailty is an important outcome predictor in patients with aortic stenosis who are candidates for transcatheter or surgical aortic valve replacement (AVR). Growth/differentiation factor 15 (GDF15) is a cytokine playing a role in the patho...
Motivation: To increase the efficiency of the brake valve by adding a corrective member. Background: The speed of response and smooth transition between modes of operation in the braking system are the primary research questions. Objective and resear...
Introduction: Emphysematous endocarditis is caused by the gas-forming organisms Citrobacter koseri, Escherichia coli, Clostridium species, and Finegoldia magna. We report the first case of emphysematous endocarditis caused by Enterococcus faecalis. C...
Myxomatous mitral valve prolapse (MMVP) and fibroelastic deficiency (FED) are two common variants of degenerative mitral valve disease (DMVD), which is a leading cause of mitral regurgitation worldwide. While pathohistological studies have revealed d...
Purpose: To assess the applicability of computational fluid dynamics (CFDs) in determining the flow parameters of inter-chamber nozzle openings in the differential section of a trailer air brake valve. Methodology: Numerical calculations were perform...
Structural valve deterioration (SVD) of bioprosthetic heart valves (BHVs) has great clinical and economic consequences. Notably, immunity against BHVs plays a major role in SVD, especially when implanted in young and middle-aged patients. However, th...
The pathobiology of ascending aorta aneurysms (AAA) onset and progression is not well understood and only partially characterized. AAA are also complicated in case of bicuspid aorta valve (BAV) anatomy. There is emerging evidence about the crucial ro...
Objectives: Calcific aortic valve disease (CAVD) is most common in the aging population and is without effective medical treatments. Brain and muscle ARNT-like 1 (BMAL1) is related to calcification. It has unique tissue-specific characteristics and p...
Calcific aortic valve stenosis (CAVS) is a heart disease characterized by the progressive fibro-calcific remodeling of the aortic valves, an actively regulated process with the involvement of the reactive oxygen species-mediated differentiation of va...
Vascular calcification is a complex, regulated process characterized by the pathological deposition of calcium phosphate minerals in the vascular wall, contributing to cardiovascular morbidity and mortality, particularly in patients with chronic kidn...
Despite the great progress in the field of bone tissue regeneration, the early initiating mechanisms of osteogenic differentiation are not well understood. Cells capable of osteogenic transformation vary from mesenchymal stem cells of various origins...
This paper presents not only a hardware-simulator development for hydraulic turbine generation systems (HTGS) in a district heating system (DHS) but also its control strategies and sequence. Generally, a DHS uses a differential pressure control valve...
Most patients with hydrocephalus are still managed with the implantation of a cerebrospinal fluid (CSF) shunt in which the CSF flow is regulated by a differential-pressure valve (DPV). Our aim in this review is to discuss some basic concepts in fluid...
A hydraulic pressure servo system based on two high-speed on/off valves (HSV) is a discontinuous system due to the discrete flow of HSV when driven by pulse width modulation (PWM) signal. Pressure variation in the testing chamber is determined by the...
There is increasing evidence that some adult mitral valve pathologies may have developmental origins involving errors in cell signaling and protein deposition during valvulogenesis. While early and late gestational stages are well-documented in zebra...
Background and Objectives: Aortic valve stenosis (AS) develops with a pronounced local inflammatory response, where a variety of growth factors are involved in the process, and may have a pro-inflammatory and anti-inflammatory effect. The aim of our...
Background/Objectives: This study aimed to assess the effectiveness and clinical relevance of intraprocedural invasive measurements—specifically intraprocedural mean pressure gradients (IC MPGs) and diastolic delta (DD)—in comparison with...
Calcific aortic valve disease (CAVD) is a progressive inflammatory disorder characterized by extracellular matrix remodeling and valvular interstitial cells (VIC) osteodifferentiation leading to valve leaflets calcification and impairment movement. R...
This paper proposes an efficient and new modified differential evolution algorithm (ENMDE) for solving two short-term hydrothermal scheduling (STHTS) problems. The first is to take the available water constraint into account, and the second is to con...
To address the problem of flow-induced resonance in the valve core assembly of a pilot-operated molten salt regulating valve in a concentrated solar thermal power generation molten salt energy storage system under high pressure differential and high...
We proposed a novel 2D electric feedback flow control valve to solve the problem of low integration and control accuracy of flow control valves. The torque motor of the valve drives the 2D piston to rotate, and the rotational motion is converted to a...
A MEMS-based micro valve fitted with a piezoelectric actuator is presented in order to achieve a continuously adjustable flow rate control. The micro valve is realized using a cost-effective fabrication scheme with simple polyimide (PI) bonding, whic...
The valve motion strongly couples with the differential pressure between the cylinder and the suction and discharge plenum, which has a significant influence on the performance of the refrigerator compressor. To examine the interaction between the pr...
Direct-drive electro-hydraulic servo valves are used extensively in aerospace, military and control applications, but little research has been conducted on their service life and physical failure wear. Based on computational fluid dynamics, the main...
Heart valves are complex structures composed of a heterogeneous population of valve interstitial cells (VICs), an overlying endothelium and highly organized layers of extracellular matrix. Alterations in valve homeostasis are characteristic of dysfun...
Pump-controlled hydraulic circuits are proven to be more efficient than conventional valve-controlled circuits. Pump-controlled hydraulic circuits for double rod cylinders are well developed and are in use in many practical applications. Existing pum...
Overflow loss is one of the main reasons for the inefficiency of the hydraulic system. Aiming at the overflow loss in the hydraulic system, an energy recovery system based on a hydraulic motor and generator is proposed. Further, a pressure monitoring...
Transcatheter aortic valve implantation (TAVI) has become the standard of care in elderly high-risk patients with symptomatic severe aortic stenosis. Recently, TAVI has been increasingly performed in younger-, intermediate- and lower-risk populations...
Abnormal heart valve function is a major cause of heart disease and is often associated with high rates of morbidity and mortality from heart disease. Focusing on the field of valve replacement, tissue-engineered heart valves are becoming popular and...
The main valve spool structure of the pilot-operated proportional directional valve is diverse and has a direct impact on the flow field. To improve the valve’s performance, this work studied the characteristics of four types of spool structure...
The intrusion of micrometer-sensitive contaminant particles into the clearance of sliding valves within hydraulic fluids is one of the root causes of valve sticking and reliability issues in hydraulic systems. To reveal the transient process and char...
Aortic valve stenosis (AVS), a consequence of increased fibrosis and calcification of the aortic valve leaflets, causes progressive narrowing of the aortic valve. Proteoglycans, structural components of the aortic valve, accumulate in regions with fi...
Observing mitral or tricuspid valve disease in an athlete raises many considerations for the clinician. Initially, the etiology must be clarified, with causes differing depending on whether the athlete is young or a master. Notably, vigorous training...
Aortic valve interstitial cells (AVICs) play a major role in valvular calcification associated with calcific aortic valve disease (CAVD). Although AVICs from diseased valves display a pro-osteogenic phenotype, the underlying mechanism causing this re...
The speed control of a pipeline inspection gauge (PIG) directly affects the quality of the comprehensive inspection of submarine pipelines. However, the mechanism of the gas flow behavior in a pipeline under the influence of a pig speed control valve...
Calcific aortic valve disease is the most common valvular heart disease in industrialized countries. Pulsatile pressure, sheer and bending stress promote initiation and progression of aortic valve degeneration. The aim of this work is to establish an...
Collagen fibers are essential structural components of mitral valve leaflets, their tension apparatus (chordae tendineae), and the associated papillary muscles. Excess or lack of collagen fibers in the extracellular matrix (ECM) in any of these struc...
Previous researchers mostly carried out simulation research and scattered experimental research on the static and dynamic characteristics of the digital valve, but did not form a systematic and in-depth study on the characteristics of the valve. Base...
Clinically used heart valve prostheses, despite their progress, are still associated with limitations. Biodegradable poly-ε-caprolactone (PCL) nanofiber scaffolds, as a matrix, were seeded with human endothelial colony-forming cells (ECFCs) a...
Lipoprotein(a) (Lp(a)) is one of the most important risk factors for the development of calcific aortic valve stenosis (CAVS). However, the mechanisms through which Lp(a) causes CAVS are currently unknown. Our objectives were to characterize the Lp(a...
O-type ball valves are common flow devices that are widely used in different industrial applications. A vibration often occurs when fluid flows through O-type ball valves, and it affects the efficiency and reliability of industrial systems. In this p...
Valves are important components in controlling the amount of fluid going to devices. One of these types is the butterfly valve (BFV) that adjusts the amount of flow by rotating the valve disk by means of its shafts which is usually located in the mid...
Differential imaging in the evaluation of mitral valve insufficiency In current clinical practice, choosing the optimal imaging technique for the quantification and differential diagnosis of mitral valve insufficiency constitutes a challenge, even fo...
Valve-controlled hydraulic actuation systems are favored in many applications due to their fast response, high power-to-weight ratio, and stability under variable working conditions. Efficiency, however, is the main disadvantage of these systems. Pum...
Acquired von Willebrand syndrome (AVWS) is caused by an acquired deficiency of von Willebrand factor (VWF), a multimeric protein required for primary hemostasis. For patients with heart valve diseases, high gradient across the malfunctioning valves c...
Control valves in nuclear systems operate under high-pressure differentials generating intense transient fluid forces that induce destructive structural vibrations, risking resonance and the valve stem fracture. In this study, computational fluid dyn...
The incidence of rheumatic fever (RF) has markedly decreased in Europe since the beginning of the 20th century due to improved living conditions, early antibiotic therapy in streptococcal pharyngitis, and changes in serotypes of circulating streptoco...
of 5