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120,793 Results Found

  • Editorial
  • Open Access
2 Citations
4,182 Views
3 Pages

Computational Complexity

  • J. A. Tenreiro Machado and
  • António M. Lopes

7 February 2017

Complex systems (CS) involve many elements that interact at different scales in time and space. The challenges in modeling CS led to the development of novel computational tools with applications in a wide range of scientific areas. The computational...

  • Article
  • Open Access
1 Citations
1,060 Views
19 Pages

19 November 2024

This paper studies the computational complexity of subclasses of semiperfect rings from the perspective of computability theory. A ring is semiperfect if the identity can be expressed as a sum of mutually orthogonal local idempotents. Semisimple ring...

  • Review
  • Open Access
8 Citations
6,366 Views
48 Pages

Computational Metagenomics: State of the Art

  • Marco Antonio Pita-Galeana,
  • Martin Ruhle,
  • Lucía López-Vázquez,
  • Guillermo de Anda-Jáuregui and
  • Enrique Hernández-Lemus

20 September 2025

Computational metagenomics has revolutionized our understanding of the human microbiome, enabling the characterization of microbial diversity, the prediction of functional capabilities, and the identification of associations with human health outcome...

  • Editorial
  • Open Access
4 Citations
3,106 Views
6 Pages

Computational Intelligence in Remote Sensing: An Editorial

  • Manuel Graña,
  • Michal Wozniak,
  • Sebastian Rios and
  • Javier de Lope

23 January 2020

Computational intelligence is a very active and fruitful research of artificial intelligence with a broad spectrum of applications. Remote sensing data has been a salient field of application of computational intelligence algorithms, both for the exp...

  • Article
  • Open Access
5 Citations
4,138 Views
11 Pages

24 November 2021

In order to reduce the hemodialysis cost and duration, an investigation of the effect of dialyzer design and process variables on the solute clearance rate is required. It is not easy to translate the in vivo transfer process with in vitro experiment...

  • Article
  • Open Access
977 Views
22 Pages

Computational Play in Early Childhood: Integrating Analog and Digital Tools to Support Mathematical Learning and Computational Thinking

  • Eva Brooks,
  • Camilla Finsterbach Kaup,
  • Susanne Dau,
  • Emma Edstrand,
  • Francesca Granone and
  • Elin Kirsti Lie Reikerås

27 November 2025

Although play naturally embeds computational thinking (CT) and mathematical learning in early childhood education, designing developmentally appropriate learning activities that purposefully nurture and extend these competencies remains a challenge....

  • Review
  • Open Access
2 Citations
2,885 Views
37 Pages

Singularities in Computational Optics

  • S. Deepa,
  • Kedar Khare and
  • Senthilkumaran Paramasivam

22 January 2025

Phase singularities in optical fields are associated with a non-vanishing curl component of phase gradients. Huygen’s diverging spherical wavefronts that primary/secondary point sources emit, during propagation, a have zero curl component. Ther...

  • Article
  • Open Access
10 Citations
2,861 Views
18 Pages

24 September 2020

Resources related to remote-sensing data, computing, and models are scattered globally. The use of remote-sensing images for disaster-monitoring applications is data-intensive and involves complex algorithms. These characteristics make the timely and...

  • Feature Paper
  • Review
  • Open Access
58 Citations
13,173 Views
20 Pages

Computational Studies on Acetylcholinesterases

  • Yechun Xu,
  • Shanmei Cheng,
  • Joel L. Sussman,
  • Israel Silman and
  • Hualiang Jiang

10 August 2017

Functions of biomolecules, in particular enzymes, are usually modulated by structural fluctuations. This is especially the case in a gated diffusion-controlled reaction catalyzed by an enzyme such as acetylcholinesterase. The catalytic triad of acety...

  • Perspective
  • Open Access
13 Citations
4,929 Views
8 Pages

6 December 2019

The revolution in next-generation DNA sequencing technologies is leading to explosive data growth in genomics, posing a significant challenge to the computing infrastructure and software algorithms for genomics analysis. Various big data technologies...

  • Article
  • Open Access
7 Citations
7,121 Views
20 Pages

Exploring the Computational Explanatory Gap

  • James A. Reggia,
  • Di-Wei Huang and
  • Garrett Katz

While substantial progress has been made in the field known as artificial consciousness, at the present time there is no generally accepted phenomenally conscious machine, nor even a clear route to how one might be produced should we decide to try. H...

  • Proceeding Paper
  • Open Access
1,623 Views
3 Pages

Eco-cognitive computationalism sees computation in context, adopting the intellectual visions advanced by the cognitive science perspectives on embodied, situated, and distributed cognition. It is in this framework that we can fruitfully study the re...

  • Article
  • Open Access
7 Citations
5,097 Views
24 Pages

8 December 2021

We build an analysis based on the Algorithmic Information Theory of computational creativity and extend it to revisit computational aesthetics, thereby, improving on the existing efforts of its formulation. We discuss Kolmogorov complexity, models an...

  • Article
  • Open Access
19 Citations
4,635 Views
19 Pages

Optimal Computational Power Allocation in Multi-Access Mobile Edge Computing for Blockchain

  • Yuan Wu,
  • Xiangxu Chen,
  • Jiajun Shi,
  • Kejie Ni,
  • Liping Qian,
  • Liang Huang and
  • Kuan Zhang

15 October 2018

Blockchain has emerged as a decentralized and trustable ledger for recording and storing digital transactions. The mining process of Blockchain, however, incurs a heavy computational workload for miners to solve the proof-of-work puzzle (i.e., a seri...

  • Review
  • Open Access
15 Citations
11,787 Views
29 Pages

Computational Modelling and Simulation of Scaffolds for Bone Tissue Engineering

  • Haja-Sherief N. Musthafa,
  • Jason Walker and
  • Mariusz Domagala

Three-dimensional porous scaffolds are substitutes for traditional bone grafts in bone tissue engineering (BTE) applications to restore and treat bone injuries and defects. The use of computational modelling is gaining momentum to predict the paramet...

  • Article
  • Open Access
3 Citations
5,474 Views
15 Pages

14 December 2015

In discussions regarding models of cognition, the very mention of “computationalism” often incites reactions against the insufficiency of the Turing machine model, its abstractness, determinism, the lack of naturalist foundations, triviality and the...

  • Review
  • Open Access
7 Citations
6,527 Views
20 Pages

Computational Studies of Glutamate Transporters

  • Jeffry Setiadi,
  • Germano Heinzelmann and
  • Serdar Kuyucak

11 November 2015

Glutamate is the major excitatory neurotransmitter in the human brain whose binding to receptors on neurons excites them while excess glutamate are removed from synapses via transporter proteins. Determination of the crystal structures of bacterial a...

  • Article
  • Open Access
5 Citations
6,158 Views
26 Pages

Assessing Computational Thinking in Engineering and Computer Science Students: A Multi-Method Approach

  • Farman Ali Pirzado,
  • Awais Ahmed,
  • Sadam Hussain,
  • Gerardo Ibarra-Vázquez and
  • Hugo Terashima-Marin

11 March 2025

The rapid integration of computational thinking (CT) into STEM education highlights its importance as a critical skill for problem-solving in the digital age, equipping students with the cognitive tools needed to address complex challenges systematic...

  • Review
  • Open Access
21 Citations
7,950 Views
30 Pages

Review of Miniaturized Computational Spectrometers

  • Qingze Guan,
  • Zi Heng Lim,
  • Haoyang Sun,
  • Jeremy Xuan Yu Chew and
  • Guangya Zhou

27 October 2023

Spectrometers are key instruments in diverse fields, notably in medical and biosensing applications. Recent advancements in nanophotonics and computational techniques have contributed to new spectrometer designs characterized by miniaturization and e...

  • Review
  • Open Access
18 Citations
6,282 Views
16 Pages

15 January 2021

Computational creativity in built environment (BE) design has been a subject of research interest in the discipline. This paper presents a critical review of various ways computational creativity has been and can be defined and approached in BE desig...

  • Article
  • Open Access
8 Citations
3,370 Views
25 Pages

10 February 2021

Representation and abstraction are two of the fundamental concepts of computer science. Together they enable “high-level” programming: without abstraction programming would be tied to machine code; without a machine representation, it would be a pure...

  • Feature Paper
  • Article
  • Open Access
34 Citations
4,815 Views
11 Pages

2 December 2019

Reservoir computing has rekindled neuromorphic computing in photonics. One of the simplest technological implementations of reservoir computing consists of a semiconductor laser with delayed optical feedback. In this delay-based scheme, virtual nodes...

  • Review
  • Open Access
102 Citations
27,352 Views
35 Pages

Application of Computational Biology and Artificial Intelligence in Drug Design

  • Yue Zhang,
  • Mengqi Luo,
  • Peng Wu,
  • Song Wu,
  • Tzong-Yi Lee and
  • Chen Bai

5 November 2022

Traditional drug design requires a great amount of research time and developmental expense. Booming computational approaches, including computational biology, computer-aided drug design, and artificial intelligence, have the potential to expedite the...

  • Article
  • Open Access
7 Citations
3,375 Views
19 Pages

26 October 2024

Computer vision education is increasingly important in modern technology curricula; yet, it often lacks a systematic approach integrating both theoretical concepts and practical applications. This study proposes a staged framework for computer vision...

  • Article
  • Open Access
2 Citations
3,604 Views
19 Pages

5 September 2024

This quasi-experimental study investigated the impact of computational learning activities on high school students’ computational thinking (CT) and computational modeling (CM) skills. High school students (n = 90) aged 16 to 19 engaged in activ...

  • Article
  • Open Access
1 Citations
2,161 Views
22 Pages

Computational Test for Conditional Independence

  • Christian B. H. Thorjussen,
  • Kristian Hovde Liland,
  • Ingrid Måge and
  • Lars Erik Solberg

24 July 2024

Conditional Independence (CI) testing is fundamental in statistical analysis. For example, CI testing helps validate causal graphs or longitudinal data analysis with repeated measures in causal inference. CI testing is difficult, especially when test...

  • Article
  • Open Access
9 Citations
4,888 Views
10 Pages

This paper presents a theoretical study of the binary oppositions underlying the mechanisms of natural computation understood as dynamical processes on natural information morphologies. Of special interest are the oppositions of discrete vs. continuo...

  • Communication
  • Open Access
18 Citations
5,283 Views
19 Pages

10 September 2020

Today’s technological development inevitably defies educational approaches in terms of future demand for skills to be imparted. Among other skills, the capacity to operate and communicate effectively within multidisciplinary realms is duly cons...

  • Article
  • Open Access
7 Citations
3,813 Views
16 Pages

19 July 2022

Mobile edge computing (MEC) sinks the functions and services of cloud computing to the edge of the network to provide users with storage and computing resources. For workflow tasks, the interdependency and the sequence constraint being among the task...

  • Article
  • Open Access
1 Citations
5,855 Views
12 Pages

In the age of digitization, the world seems to be reducible to a digital computer. However, mathematically, modern quantum field theories do not only depend on discrete, but also continuous concepts. Ancient debates in natural philosophy on atomism v...

  • Article
  • Open Access
1,957 Views
27 Pages

27 November 2024

The rising popularity of UAVs and other autonomous control systems coupled with real-time operating systems has increased the complexity of developing systems with the proper robustness, performance, and reactivity. The growing demand for more sophis...

  • Article
  • Open Access
6 Citations
3,328 Views
20 Pages

The paper is written to demonstrate the applicability of the notion of triangulation typically used in social sciences research to computationally enhance the mathematics education of future K-12 teachers. The paper starts with the so-called Brain Te...

  • Feature Paper
  • Review
  • Open Access
18 Citations
6,869 Views
42 Pages

Computational Fluid–Structure Interaction in Microfluidics

  • Hafiz Muhammad Musharaf,
  • Uditha Roshan,
  • Amith Mudugamuwa,
  • Quang Thang Trinh,
  • Jun Zhang and
  • Nam-Trung Nguyen

Micro elastofluidics is a transformative branch of microfluidics, leveraging the fluid–structure interaction (FSI) at the microscale to enhance the functionality and efficiency of various microdevices. This review paper elucidates the critical...

  • Commentary
  • Open Access
18 Citations
10,109 Views
3 Pages

1 September 2017

Biomarkers are cornerstones of clinical medicine, and personalized medicine, in particular, is highly dependent on reliable and highly accurate biomarkers for individualized diagnosis and treatment choice. Modern omics technologies, such as genome se...

  • Article
  • Open Access
2 Citations
2,071 Views
15 Pages

Computational “Accompaniment” of the Introduction of New Mathematical Concepts

  • Andrey Lavrenov,
  • Elena Tolkacheva and
  • Sergei Pozdniakov

The computational capabilities of computer tools expand the student’s search capabilities. Conducting computational experiments in the classroom is no longer an organizational problem. This raises the “black box” problem, when the s...

  • Proceeding Paper
  • Open Access
2 Citations
2,379 Views
7 Pages

iFogSim Simulations on IoT Computational Alternatives

  • Romolo Paesani,
  • Gaetanino Paolone,
  • Paolino Di Felice,
  • Danilo Iachetti and
  • Martina Marinelli

14 December 2022

This study proposes the adoption of the IoT technology for the home monitoring of the health status of frail patients. Such a solution is thought to be part of the forthcoming Italian COT; the latter is an organizational model which is devoted to int...

  • Article
  • Open Access
5 Citations
4,569 Views
24 Pages

5 December 2019

Container terminals are the typical representatives of complex supply chain logistics hubs with multiple compound attributes and multiple coupling constraints, and their operations are provided with the strong characteristics of dynamicity, nonlinear...

  • Article
  • Open Access
42 Citations
5,770 Views
18 Pages

Computational Analysis of Molnupiravir

  • Artem V. Sharov,
  • Tatyana M. Burkhanova,
  • Tugba Taskın Tok,
  • Maria G. Babashkina and
  • Damir A. Safin

28 January 2022

In this work, we report in-depth computational studies of three plausible tautomeric forms, generated through the migration of two acidic protons of the N4-hydroxylcytosine fragment, of molnupiravir, which is emerging as an efficient drug to treat CO...

  • Article
  • Open Access
8 Citations
10,393 Views
12 Pages

22 November 2012

We survey a few aspects of the thermodynamics of computation, connecting information, thermodynamics, computability and physics. We suggest some lines of research into how information theory and computational thermodynamics can help us arrive at a be...

  • Review
  • Open Access
21 Citations
7,326 Views
18 Pages

Combining Experimental Data and Computational Methods for the Non-Computer Specialist

  • Reinier Cárdenas,
  • Javier Martínez-Seoane and
  • Carlos Amero

18 October 2020

Experimental methods are indispensable for the study of the function of biological macromolecules, not just as static structures, but as dynamic systems that change conformation, bind partners, perform reactions, and respond to different stimulus. Ho...

  • Article
  • Open Access
8 Citations
3,629 Views
15 Pages

19 September 2020

Although natural and bioinspired computing has developed significantly, the relationship between the computational universality and efficiency beyond the Turing machine has not been studied in detail. Here, we investigate how asynchronous updating ca...

  • Review
  • Open Access
3 Citations
3,811 Views
20 Pages

Forward Computational Modeling of Respiratory Airflow

  • Emmanuel A. Akor,
  • Bing Han,
  • Mingchao Cai,
  • Ching-Long Lin and
  • David W. Kaczka

12 December 2024

The simulation of gas flow in the bronchial tree using computational fluid dynamics (CFD) has become a useful tool for the analysis of gas flow mechanics, structural deformation, ventilation, and particle deposition for drug delivery during spontaneo...

  • Review
  • Open Access
16 Citations
6,638 Views
24 Pages

17 December 2020

Cognitive inflexibility is a well-documented, yet non-specific corollary of many neurological diseases. Computational modeling of covert cognitive processes supporting cognitive flexibility may provide progress toward nosologically specific aspects o...

  • Article
  • Open Access
1,924 Views
23 Pages

A Computational Approach to the Perimeter-Area Inequality in a Triangle

  • Tomás Recio,
  • Carlos Ueno and
  • María Pilar Vélez

5 January 2025

This paper explores the application of automated reasoning tools, specifically those implemented in GeoGebra Discovery, to the perimeter-area inequality in triangles. Focusing on the computational complex and real algebraic geometry methods behind th...

  • Article
  • Open Access
1,065 Views
27 Pages

Introduction: Bioinformatics is a relatively recent multidisciplinary research field continuously offering novel opportunities. Although many researchers are actively working in/with bioinformatics, some research centers still face difficulties in hi...

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