Coiled-coils, the bundles of intertwined helical protein motifs, have drawn much attention as versatile molecular toolkits. Because of programmable interaction specificity and affinity as well as well-established sequence-to-structure relationships,...
In this paper, we report the synthesis and self-assembly behavior of coil-rod-coil molecules, consisting of three biphenyls linked through a vinylene unit as a conjugated rod segment and poly(ethylene oxide) (PEO) with a degree of polymerization (DP)...
One of the most desirable properties that biomaterials designed for tissue engineering or drug delivery applications should fulfill is biodegradation and resorption without toxicity. Therefore, there is an increasing interest in the development of bi...
Conjugated polymers (CPs), in particular poly(p-phenylene vinylene)s (PPVs), are recognized as “smart” materials with potential applications ranging from optoelectronic devices to emergent technologies and to precision medicine. The prese...
The creation and exploitation of gas turbine engines (GTE) often involve two mutually exclusive tasks related to ensuring the highest reliability while achieving a good economic and environmental performance of the power plant. The value of the radia...
G protein-coupled receptor (GPCR) structures are of interest as a means to understand biological signal transduction and as tools for therapeutic discovery. The growing number of GPCR crystal structures demonstrates that the extracellular loops (EL)...
Energy efficiency and leakage magnetic field (LMF) are two important issues in electric vehicle inductive chargers. In this work, the maximum achievable coil efficiency and the corresponding LMF strength are formulated as functions of system paramete...
Coils are one of the basic elements employed in devices. They are versatile, in terms of both design and manufacturing, according to the desired inductive specifications. An important characteristic of coils is their bidirectional action; they can bo...
Polypeptoids, a class of synthetic peptidomimetic polymers, have attracted increasing attention due to their potential for biotechnological applications, such as drug/gene delivery, sensing and molecular recognition. Recent investigations on the solu...
Fabricating hierarchical nanomaterials by self-assembly of rod-coil block copolymers attracts great interest. However, the key factors that affect the formation of the hierarchical nanomaterials have not been thoroughly researched. Herein, we have sy...
Protein nanotubes offer unique properties to the materials science field that allow them to fulfill various functions in drug delivery, biosensors and energy storage. Protein nanotubes are chemically diverse, modular, biodegradable and nontoxic. Furt...
Variably reduced expression of the basement membrane component laminin-332 (α3aβ3γ2) causes junctional epidermolysis bullosa generalized intermediate (JEB-GI), a skin fragility disorder with an increased susceptibility to squamous ce...
Block copolymers have attracted significant scientific and economic interest over the last decades due to their ability to self-assemble into ordered structures both in bulk and in selective solvents. In this work, the self-assembly behaviour of both...
In the example of the aviation gas turbine engine the problem of monitoring metal wear particles of friction pairs in the oil systems of gas turbine power plants is considered. The solution based on using the multi-channel cluster single-coil eddy cu...
Here we report the dual light- and thermo-responsive behavior of well-defined rod-coil block copolymers composed of an azobenzene unit, 2-(2-methoxyethoxy)ethyl methacrylate (MEO2MA) and oligo(ethylene glycol) methacrylate (OEGMA). Azobenzene-contain...
Protein complexes perform a diversity of functions in natural biological systems. While computational protein design has enabled the development of symmetric protein complexes with spherical shapes and hollow interiors, the individual subunits often...
The molecular architecture and assembly mechanism of intermediate filaments have been enigmatic for decades. Among those, lamin filaments are of particular interest due to their universal role in cell nucleus and numerous disease-related mutations. F...
24 October 2020
In electronic nicotine delivery systems (ENDS), coil resistance is an important factor in the generation of heat energy used to change e-liquid into vapor. An accurate and unbiased method for testing coil resistance is vital for understanding its eff...
Desmin is the major intermediate filament protein of all three muscle cell types, and connects different cell organelles and multi-protein complexes such as the cardiac desmosomes. Several pathogenic mutations in the DES gene cause different skeletal...
Biomineralization peptides are versatile tools for generating nanostructures since they can make specific interactions with various inorganic metals, which can lead to the formation of intricate nanostructures. Previously, we examined the influence t...
A non-destructive evaluation method is proposed to identify the sectional loss of the external tendon of prestressed concrete structures by detecting the change of the magnetic flux in the external tendon exposed to a magnetic field. The method uses...
The soluble N-ethylmaleimide-sensitive factor (NSF) attachment protein (SNAP) receptor (SNARE) proteins play a central role in most forms of intracellular membrane trafficking, a key process that allows for membrane and biocargo shuffling between mul...
High-efficiency inductive power transfer (IPT) with low misalignment effects is a key issue in the dynamic charging of electric vehicle (EV) systems. In this study, an advanced concept of analysis and design of transmitter and receiver coils with a s...
The geometry of the coils in a magnetic link and their relative position are crucial for increasing their mutual inductance, which is important for obtaining a higher induced voltage, transferred power, and electrical efficiency. General design guide...
Substrate channeling could be very useful for plant metabolic engineering; hence, we propose that functionalized supramolecular self-assembly scaffolds can act as enzymatic hubs able to perform reactions in close contiguity. Virus nanoparticles (VNPs...
Myosin dimers arranged in layers and interspersed with non-myosin densities have been described by cryo-EM 3D reconstruction of the thick filament in Lethocerus at 5.5 Å resolution. One of the non-myosin densities, denoted the ‘red density’, is hypot...
The cytoskeleton of the eukaryotic cell provides a structural and functional scaffold enabling biochemical and cellular functions. While actin and microtubules form the main framework of the cell, intermediate filament networks provide unique mechani...
The fabrication of electroplated planar copper microcoils for telemetric orthodontic applications is presented. A set of microcoils with overall dimensions of 2 × 2.5 × 0.5 mm3, track widths down to 5 μm and turn numbers up to 35 were fabricated on g...
Active drug delivery systems for cancer therapy are gaining attention for their biocompatibility and enhanced efficacy compared to conventional chemotherapy and surgery. To improve precision in targeted drug delivery (TDD), actuating devices using ex...
In this paper, the design of novel slotless permanent magnet synchronous motor (PMSM) for a collaborative robot was studied considering the manufacture process of winding. The winding manufacture process of novel slotless PMSM was proposed in three s...
Contactless readout of passive LC sensors composed of a capacitance sensor connected to a coil can be performed through an electromagnetically coupled readout coil set at distance d. Resonant frequency fs and Q-factor QS of the LC sensor can be extra...
Magnetic pulse welding of overlapping dissimilar metallic sheets is an emerging technique and usually employs flat electromagnetic coils with rectangular-, H-, I-, and E-shaped cross-sections. The asymmetric cross-section of these coils results in a...
Wirelessly powered medical microrobots are often driven or localized by magnetic resonance imaging coils, whose signal-to-noise ratio is easily affected by the power transmitter coils that supply the microrobot. A controlled single-sided wireless pow...
Designs of saturated-cores fault current limiters (FCLs) usually implement conducting or superconducting DC coils serving to saturate the magnetic cores during nominal grid performance. The use of coils adds significantly to the operational cost of t...
In this paper, an original method of synthesis of Coil-Brush amphiphilic polystyrene-b-(polyglycidol-g-polyglycidol) (PS-b-(PGL-g-PGL)) block copolymers was developed. The hypothesis that their hydrophilicity and micellization can be controlled by po...
The article is devoted to the study of losses in devices based on high-temperature superconductors of the 2nd generation. The complexity of the devices under study increases from a single rack coil to a winding assembled from several coils, and final...
This paper catalogues a series of experiments we conducted to explore how to 3D print a DC electric motor. The individual parts of the electric motor were 3D printed but assembled by hand. First, we focused on a rotor with soft magnetic properties, f...
Neurons release neurotransmitters at a specialized region of the presynaptic membrane, the active zone (AZ), where a complex meshwork of proteins organizes the release apparatus. The formation of this proteinaceous cytomatrix at the AZ (CAZ) depends...
Smart NFC tags are seeing many interesting applications and can benefit from further miniaturization. A passive temperature sensing tag with 5.1 mm diameter is demonstrated, comprising a thin-film microfabricated antenna and an NFC chip. The microant...
High-precision sensor co-registration is a critical prerequisite for achieving high-resolution imaging in Optically Pumped Magnetometer–Magnetoencephalography (OPM-MEG) systems. The conventional magnetic dipole fitting method, essentially a mul...
Cell-based assays are essential for virus functional characterization in fundamental and applied research. Overcoming the limitations of virus-labelling strategies while allowing functional assessment of critical viral enzymes, virus-induced cell-bas...
Coiled-coil domains (CCDs) play key roles in regulating both healthy cellular processes and the pathogenesis of various diseases by controlling protein self-association and protein–protein interactions. Here, we probe the mechanism of oligomeri...
The state detection of power cables is very important to ensure the reliability of the power supply. Traditional sensors are mostly based on electric field detection. The operation is complex, and its efficiency needs to be improved. This paper optim...
Permanent magnet synchronous motors (PMSMs) are highly affected by magnetization, which determines the magnetization level in the permanent magnet (PM). There are three main magnetization methods: single-unit, stator coil, and post-assembly magnetiza...
Coil–rod copolymers with a dendritic polyethylene (DPE) core and multiple helical poly(γ-benzyl-L-glutamate) (PBLG) arms (DPE-(PBLG)n) were prepared by palladium-catalyzed copolymerization in tandem with ring-opening polymerization (ROP)....
Given the role of intermediate filaments (IFs) in normal cell physiology and scores of IF-linked diseases, the importance of understanding their molecular structure is beyond doubt. Research into the IF structure was initiated more than 30 years ago,...
The self-assembly of porphyrins onto polyelectrolytes could lead to interesting changes in their reactivity with respect to the bulk solution. Here, we investigated the kinetics of Zn2+ incorporation into tetra-cationic water-soluble 5,10,15,20-tetra...
The electromagnetic process happening between an induction brazing coil and the brazing assembly was studied and is described in the following pages. Using the tools of numerical analysis, we managed to achieve 3-D simulation of the process, which in...
A prototype of a wireless vacuum microsensor combining the Pirani principle and surface acoustic waves (SAW) with extended range and sensitivity was designed, modelled, manufactured and characterised under different conditions. The main components of...
A series of bent-shaped molecules, consisting of dibenzo[a,c]phenazine and phenyl groups connected together as a rod segment, and poly(ethylene oxide) (PEO) with a degree of polymerization (DP) of 6 as the coil segment, were synthesized. The self-ass...
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