Approximately 3–13% of patients with psoriasis are first affected after age 60 years. Numerous studies have investigated the use of biologic agents for the treatment of psoriasis, but the routine exclusion of elderly adults from clinical trials...
The programmed death-1 (PD-1) receptor plays a major physiological role in the maintenance of immune tolerance and, by interaction with its ligands (PD-L1 and PD-L2), prevents the development of multiple immune-mediated diseases. There is growing evi...
CD (cluster of differentiation) 69 and CD25 are considered early and late markers of the activation of lymphocytes, respectively. CD25 is a part of the IL-2 receptor and is present on the surface of immune and non-immune cells, with high amounts on a...
Background/Objectives: The emergence of biologic therapies has transformed the management of severe asthma, offering targeted treatments that improve symptom control and reduce exacerbations. However, taking a biologic solely based on the initial res...
Background: Previously, our cross-sectional observational study in Japan revealed high (68%) discordance within treatment goals between psoriasis patients and their physicians. Objective: This secondary analysis aimed to determine whether patient and...
A rotating biological contactor (RBC) offers a low energy footprint but suffers from performance instability, making it less popular for domestic wastewater treatment. This paper presents a study on an RBC integrated with membrane technology in which...
The rotating biological contactor (RBC) is resistant to toxic chemical and shock loadings, and this results in significant organic and nutrient removal efficiencies. The RBC system offers a low-energy footprint and saves up to 90% in energy costs. Du...
A rotating biological contactor (RBC) is a type of attached-growth biological wastewater treatment system and a widely used biological wastewater treatment technology. It employs a series of rotating discs to support microbial growth and promote the...
Background: We aimed to analyse the effectiveness, efficiency, and safety of initial treatment with biological therapies in rheumatoid arthritis (RA). Methods: Qualitative study. A group of RA experts was selected. A scoping review in Medline was con...
Physical and biological treatment technology are considered a highly feasible and economic way to treat slaughterhouse wastewater. To achieve the desired effluent quality for disposal or reuse, various technological options were reviewed. However, mo...
Psoriasis is a chronic systemic inflammatory disease that primarily affects the skin and is associated with multiple comorbidities with a considerable reduction in quality of life of affected patients. One-third of psoriasis cases begin in childhood...
Background and Objectives: Severe, recalcitrant cases of pediatric psoriasis or atopic dermatitis may necessitate treatment with biological agents; however, this may be difficult due to lack of treatment options and standardized treatment guidelines....
Juvenile idiopathic arthritis (JIA) is one of the most frequent diseases in the practice of pediatric rheumatology. JIA treatments have been modified and improved with the use of biological drugs along with technological innovations. However, differe...
A large amount of wastewater is directly discharged into water bodies without treatment, causing surface water contamination. A rotating biological contactor (RBC) is an attached biological wastewater treatment process that offers a low energy footpr...
Drinking water treatment, from a microbiological perspective, efficiently removes hygienically relevant microorganisms, making the water safe for human consumption. The water quality is strictly regulated. An aspect that is often overlooked, however,...
In the available literature, little attention has been paid to the assessment of psoriasis and the biological therapy used for it and the nervous system. The purpose of this article is to discuss the relationship between psoriasis and the nervous sys...
Biological drugs have prompted a revolution in the treatment of patients with psoriasis because of their favourable efficacy/risk profile. The aims of our study are to determine whether there is any difference in the pattern of use of biological trea...
Background: B cells are central to the pathogenesis of systemic lupus erythematosus (SLE). We aimed to analyze the efficacy and safety of new B cell-targeted drug therapies for SLE. Methods: A systematic review of randomized controlled trials (RCTs)...
International contracts to restrict emissions of climate-relevant gases, and thus global warming, also require a critical reconsideration of technologies for treating municipal, commercial, industrial, and agricultural waste gas emissions. A change f...
This comprehensive review critically examines the current state of research on the biological effects of millimeter-wave (MMW) therapy and its potential implications for disease treatment. By investigating both the thermal and non-thermal impacts of...
POME is the most voluminous waste generated from palm oil milling activities. The discharge of POME into the environment without any treatment processing could inflict an undesirable hazard to humans and the environment due to its high amount of toxi...
Volatile organic compounds (VOC) are major contributors to the burgeoning air pollution issue, predominantly from industrial areas, with well-documented environmental and health risks, which demand efficient and sustainable control policies. This rev...
Atopic dermatitis is a heterogenous inflammatory disease with high variety in terms of clinical symptoms and etiopathogenesis, occurring both in pediatric and adult populations. The clinical manifestation of atopic dermatitis varies depending on the...
This exploration investigates integrated treatment systems combining advanced oxidation processes (Fenton and photo-Fenton) with biological methods for the effective elimination of stubborn organic compounds in simulated textile wastewater composed o...
Various wastewater treatment technologies are available today and biological processes are predominantly used in these technologies. Increasing wastewater treatment systems produces large amounts of sewage sludge with variable quantities and qualitie...
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The COVID-19 pandemic and the related measures brought a change in daily life that affected the characteristics of the municipal wastewater and further, of the biological activated sludge. The activated sludge process is the most widely used biologic...
The development of biologic agents for therapeutic purposes, or biomedicines, has seen an active area of research both at the bench and in clinical trials. There is mounting evidence that biologic products can provide effective therapy for diseases t...
Objectives: to evaluate our real-world data on the efficacy and safety of switching between two monoclonal antibodies in biologic treatment of uncontrolled chronic rhinosinusitis with nasal polyps (CRSwNP). Methods: All patients receiving biologic tr...
Carbon emissions accounting of wastewater treatment systems is essential for understanding their energy efficiency and greenhouse gas emissions. To overcome the inefficiencies and high uncertainty of traditional carbon emission accounting methods in...
The efficacy of biological treatment for severe uncontrolled chronic rhinosinusitis with nasal polyps (CRSwNP) has recently been demonstrated through double-blinded clinical trials. The aim of this study was to provide preliminary real-world experien...
Persistent luminescence nanoparticles (PLNPs) represent a unique class of optical materials. They possess the ability to absorb and store energy from external excitation sources and emit light persistently once excitation terminates. Because of this...
The biological treatment of the aqueous residue produced during poplar wood pyrolysis was investigated. The biological treatment experiments were carried out at two different pH conditions (controlled at 7, uncontrolled) in batch mode at three differ...
The mechanical-biological waste treatment plants (MBTP), which include the municipal waste biogas plants, have an important role in sustainable urban development. Some plants are equipped with a sewage pre-treatment plant, which is then directed to t...
Produced water (PW) is the most significant waste stream generated in the oil and gas industries. The generated PW has the potential to be a useful water source rather than waste. While a variety of technologies can be used for the treatment of PW fo...
The global dairy sector produces upwards of 900 million tonnes of milk each year, resulting in 2.25 billion tonnes of wastewater being generated. This is significant in the South African context as a large percentage of the population lives without r...
The aim of this study was to investigate the effect of ultrasonic treatment on the physicochemical properties and bioactivities of polysaccharides from Sargassum samples (SPs) extracted with different solvents. The alkali-assisted extraction of polys...
Introduction: Inflammatory bowel disease is a chronic inflammatory disorder of the gastrointestinal tract. Biologic drugs target specific molecules in the body’s immune system to control inflammation. Recent studies have suggested a potential l...
Objectives: Spondyloarthritis (SpA) is a chronic inflammatory arthritis that mainly affects the sacroiliac joints and spine. Despite effective biological treatments, persistent pain is common in SpA patients, potentially due to central sensitization...
This review emphasizes the significance of formulating control strategies for biological and advanced oxidation process (AOP)-based wastewater treatment systems. The aim is to guarantee that the effluent quality continuously aligns with environmental...
The results of a pilot-scale study on the influence of electric field use for stimulating the active sludge in the biological purification tank of a small capacity wastewater treatment plant (up to 600 m3/day) are presented. Through specific comparat...
According to the characteristics of aniline dyeing wastewater, aerobic biological treatment was adopted herein, and high-throughput sequencing technology was used to analyze the changes to the microbial community structure and diversity in the aerobi...
Biological nitrogen removal (BNR) in centralized and decentralized wastewater treatment systems is assumed to be driven by the same microbial processes and to have communities with a similar composition and structure. There is, however, little inform...
Biological settling ponds are a practicable approach for treating super-intensive shrimp aquaculture wastewater for almost all shrimp producers in the Vietnamese Mekong Delta (VMD). The optimization of the hydraulic retention time (HRT) of biological...
Synthetic dyes, exceeding 100,000 types on the market and produced at a global scale of over 700,000 tons annually, are extensively used in the textile industry. This industry, a leading contributor to water contamination, relies on dyes like reactiv...
It is known that both psoriasis (PSO) limited to the skin and psoriatic arthritis (PSA) increase the risk of cardiovascular complications and atherosclerosis progression by inducing systemic inflammatory response. In recent decades, the introduction...
This study evaluated the feasibility of ionizing radiation combined with coagulation–sedimentation and Fenton oxidation as a treatment method for landfill leachate. The experiments revealed a positive correlation between pollutant removal effic...
Wastewater treatment plants (WWTPs) highly contribute to the transmission of antibiotic resistance genes (ARGs) in the environment. In this work, the diversity of ermF, ermB, sul1 and int1-enconding genes was examined in the influent, the mixed liquo...
The biological treatment of second cheese whey (SCW) was investigated using two different marine cultures, the microalgae Picochlorum costavermella and the cyanobacterium Geitlerinema sp. Seawater from the coastal area of Rio, near Patras, was used f...
Background: Fecal calprotectin has emerged as a significant, validated, and non-invasive biomarker allowing for the evaluation of inflammatory bowel disease. Our study assessed the reliability of the use of faecal calprotectin as a valuable tool in t...
The adoption of biological control strategies plays a crucial role in ensuring the sustainability of organic agricultural practices. A field experiment was conducted in 2023 and 2024 to evaluate the impact of biological treatments using lactic acid b...
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