The acceleration of aging is a risk factor for numerous diseases, and diet has been identified as an especially effective anti-aging method. Currently, research on the relationship between dietary nutrient intake and accelerated aging remains limited...
3 July 2019
DNA methylation may play a critical role in aging and age-related diseases. DNA methylation phenotypic age (DNAmPhenoAge) is a new aging biomarker and predictor of chronic disease risk. While smoking is a strong risk factor for chronic diseases and i...
We aim to predict the natural aging life of 8016 ethylene propylene rubber accurately and quickly. Based on the time-temperature equivalent superposition principle, the artificial bee colony algorithm was introduced to calculate the acceleration fact...
Background: Genetic and epigenetic changes, oxidative stress and inflammation influence the rate of aging, which diseases, lifestyle and environmental factors can further accelerate. In accelerated aging (AA), the biological age exceeds the chronolog...
Individuals born preterm have shorter lifespans and elevated rates of chronic illness that contribute to mortality risk when compared to individuals born at term. Emerging evidence suggests that individuals born preterm or of low birthweight also exh...
Compared with the constant stress accelerated aging test, the step stress accelerated aging test reduces the accelerated aging test time by increasing the aging temperature step by step to obtain the aging failure life of rubber in a shorter time, bu...
Glaucoma is an age-related neurodegenerative disease characterized by progressive optic nerve damage. Accelerated biological aging, assessed using predicted age derived from fundus images, may serve as a biomarker for glaucoma progression. This study...
Factors driving accelerated biological age (BA), an important predictor of chronic diseases, remain poorly understood. This study focuses on the impact of diet and gut microbiome on accelerated BA. Accelerated Klemera–Doubal biological age (KDM...
As storage technology in electric vehicles, lithium-ion cells are subject to a continuous aging process during their service life that, in the worst case, can lead to a premature system failure. Battery manufacturers thus have an interest in the agin...
The population of cancer survivors has markedly increased due to the rapid improvements in cancer treatment. However, cancer survivors experience accelerated aging, which leads to chronic diseases and other age-related conditions, such as frailty. Th...
Background/Objectives: PhenoAge utilizes biochemical biomarkers to differentiate mortality risk in persons of the same chronological age. However, the details of the relationship between PhenoAge and lumbar spinal stenosis (LSS) remain unclear. We in...
Obesity and aging share common molecular and cellular mechanisms underlying the pathophysiology of cardiovascular diseases (CVD), which occur frequently in both conditions. DNA methylation (DNAm) age, a biomarker of the epigenetic clock, has been pro...
Rapid improvements in cancer survival led to the realization that many modalities used to treat or control cancer may cause accelerated aging in cancer survivors. Clinically, “accelerated aging” phenotypes in cancer survivors include secondary cancer...
Background: Patients with chronic obstructive pulmonary disease (COPD) often suffer from multiple morbidities, which occur in clusters and are sometimes related to accelerated aging. This study aimed to assess the disease specificity of comorbidity c...
African American women are affected by earlier onset of age-associated health deteriorations and obesity disproportionally, but little is known about the mechanism linking body mass index (BMI) and biological aging among this population. DNA methylat...
The cells in dynamic random access memory (DRAM) degrade over time as a result of aging, leading to poor performance and potential security vulnerabilities. With a globalized horizontal supply chain, aged counterfeit DRAMs could end up on the market,...
Currently, there is a wide range of materials for motorcyclists available on the market that have a significant ability to absorb impact energy. Understanding the aging processes of materials is crucial for guaranteeing the long-term durability and s...
In this study, natural extracts of plant origin were used as anti-aging compounds of biodegradable polymers. Coffee (0.5–10 wt%), cocoa, or cinnamon extracts were added to the polylactide matrix. The obtained materials were subjected to an acce...
Aiming at the accelerated aging problem that may occur during the use of high specific energy lithium-ion batteries, this article proposes a method to judge the accelerated aging of lithium-ion batteries. Taking the IC curve and DV curve as the start...
Spruce wood is widely used in outdoor applications, but its susceptibility to degradation under exposure to sunlight and moisture is a major concern. This study investigates the impact of accelerated aging on spruce wood’s surface chemistry, mi...
Background: One of the most debated topics in experimental and clinical endocrinology is the impact of hypo- and hyper-somatotropism on the extension/shortening of the lifespan, the results of experimental, clinical, and epidemiological studies being...
This work presents a semi-quantitative spectroscopic approach, including FTIR–ATR and Raman spectroscopies, for the biochemical analysis of red blood cells (RBCs) supported by the biochemical, morphological and rheological reference techniques. This...
This article presents an evaluation of the accelerated aging impact on the structural properties of biodegradable PLA/HAp implants produced using 3D printing technology for use in traumatic bone defect repairs in individual patients. The designed bio...
Reflectors for concentrated solar thermal technologies need to withstand 20 or even 30 years of outdoor exposure without significant loss of solar specular reflectance. In order to test the durability of innovative reflectors within a shorter period...
Background/Objectives: Glaucoma, a leading cause of irreversible blindness, has been associated with systemic and ocular aging processes. This study aimed to investigate the relationship between glaucoma and accelerated biological aging using fundus-...
Polyolefin geosynthetics are susceptible to oxidative degradation, which in turn leads to diminished mechanical properties in geotechnical constructions. When using these materials, it is extremely important to determine their durability over time in...
During their useful life, polymers are subject to degradation processes due to exposure to specific environmental conditions over long times. These processes generally lead to changes, almost always irreversible, of properties and performances of pol...
Ultra-high molecular weight polyethylene (UHMWPE) has been the most commonly used bearing material in total joint arthroplasty. Wear and oxidation fatigue resistance of UHMWPE are regarded as two important mechanical properties to extend the longevit...
This work addresses the durability of structural epoxy adhesives and carbon fibre reinforced polymer (CFRP) laminates typically used in strengthening of existing reinforced concrete structures exposed to natural ageing. The experimental program inclu...
The aim was to investigate how the surface treatment and the process of accelerated ageing of zirconia for dental implants affect the biaxial flexural strength and hardness. Zirconia discs with a diameter of 12.6 mm were subjected to either one of th...
Accelerated aging experiments on solar reflectors allow for a more accurate prediction of the materials’ lifespan in a shorter period of time comparing to a study on real-Concentrated solar power (CSP) sites. Accelerated aging tests help to ide...
Objectives: To investigate the association between visceral fat accumulation and the risk of cardiometabolic multimorbidity (CMM) and the potential roles of accelerated biological aging in this relationship. Methods: Using data from the UK Biobank, a...
A known association exists between exposure to gestational diabetes mellitus (GDM) and epigenetic age acceleration (EAA) in GDM-exposed offspring compared to those without GDM exposure. This association has not been assessed previously in mothers wit...
Crystalline silicon photovoltaic modules, when subjected to diverse environmental conditions, undergo progressive performance degradation due to factors such as temperature, humidity, light irradiation, and operational duration. Understanding this de...
This study focuses on two separate investigations of the main aging mechanisms: alkali–silica reactivity (ASR) and the corrosion of reinforcing steel (rebar) concrete, both of which may result in a premature failure to meet the serviceability o...
In outdoor environments, the action of the Sun through its ultraviolet radiation has a degrading effect on most materials, with polymers being among those affected. In the past few years, 3D printing has seen an increased usage in fabricating parts f...
This study investigates the impact of accelerated aging conditions on the long-term flexural behavior and ductility of reinforced concrete (RC) members with glass fiber-reinforced polymer (GFRP) bars (RC-GFRP specimen) and steel bars (RC-steel speci...
Long-term photovoltaic (PV) module reliability is highly determined by the durability of the polymeric components (backsheet and encapsulation materials). This paper presents the result of experiments on encapsulant degradation influenced by the back...
Seed ageing is associated with a high concentration of reactive oxygen species (ROS). Apple (Malus domestica Borkh.) seeds belong to the orthodox type. Due to a deep dormancy, they may be stored in dry condition at 5 °C for a long time, without v...
Seed aging during storage is irreversible, and a rapid, accurate detection method for seed vigor detection during seed aging is of great importance for seed companies and farmers. In this study, an artificial accelerated aging treatment was used to s...
Natural ageing has a major influence on the properties of paper, while light, heat, and humidity are the environmental influences that most disrupt the stability of paper. This research focuses on changes in straw-containing papers caused by accelera...
This study investigates the durability of glass fiber-reinforced polymer (GFRP) reinforcing bars (rebars) and their bond in concrete. Accelerated aging tests were first conducted on bare rebars that were either subjected to direct immersion in an alk...
Power transformers are still equipment of primary importance within power grids. The recent paradigm changes registered in the field of energy require the interconnection of electrical grids of much larger areas, even up to the level of an entire con...
The slow hardening process of carbonate-activated slag limits its application as a construction material. This paper aims to provide an acceleration method for the early age hydration of carbonate-activated slag by applying calcium silicate hydrate (...
We evaluated associations between nine epigenetic age acceleration (EAA) scores and 18 cardiometabolic phenotypes using an Eastern European ageing population cohort richly annotated for a diverse set of phenotypes (subsample, n = 306; aged 45–6...
Type 1 diabetes (T1D) is an autoimmune disease that leads to insulin deficiency and hyperglycemia. Little is known about how this metabolic dysfunction, which substantially alters the internal environment, forces cells to adapt through epigenetic mec...
Muscle atrophy is one of the main causes of sarcopenia—the age-related loss of skeletal muscle. In this study, we investigated the effect of turmeric (Curcuma longa) extract (TE) supplementation on age-related muscle atrophy in a senescence-acc...
Fluoride-containing alkali-free setting accelerators are a common type of admixture used in tunnel shotcrete but few studies in the literature focus on the effect of their fluoride compounds on the setting and hardening properties of accelerated ceme...
Titanium dioxide (TiO2) was added in different proportions as a filler to the mixture for the production of recycled rubber tiles in order to improve their existing properties. The mechanical properties of novel rubber tiles were analyzed in the cont...
Para-aramid materials such as Twaron® and Kevlar® are commonly used for ballistic-resistant body armor, which are designed to protect human life and health. For this reason, the materials from which body armor are made should be thoroughly in...
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