You are currently on the new version of our website. Access the old version .

387 Results Found

  • Review
  • Open Access
52 Citations
11,174 Views
16 Pages

Smart Materials Based on DNA Aptamers: Taking Aptasensing to the Next Level

  • Emily Mastronardi,
  • Amanda Foster,
  • Xueru Zhang and
  • Maria C. DeRosa

18 February 2014

“Smart” materials are an emerging category of multifunctional materials with physical or chemical properties that can be controllably altered in response to an external stimulus. By combining the standard properties of the advanced material with the...

  • Article
  • Open Access
1,205 Views
15 Pages

Biomechanical Comparison of Titanium and CFR-PEEK Intramedullary Nails Using Finite Element Analysis

  • Mario Ceddia,
  • Elisa Pesare,
  • Giuseppe Solarino,
  • Luciano Lamberti and
  • Bartolomeo Trentadue

27 October 2025

This study analyzes the biomechanical performance of intramedullary nails made of titanium alloy (Ti-6Al-4V) and carbon fiber-reinforced polyetheretherketone (CFR-PEEK) for the treatment of proximal femoral fractures, with a focus on their effects un...

  • Communication
  • Open Access
5 Citations
4,314 Views
13 Pages

Additive Soft Matter Design by UV-Induced Polymer Hydrogel Inter-Crosslinking

  • Talika A. Neuendorf,
  • Niclas Weigel,
  • Michelle Vigogne and
  • Julian Thiele

14 February 2022

In recent years, stimuli-responsive hydrogels have gained tremendous interest in designing complex smart 4D materials for applications ranging from biomedicine to soft electronics that can change their properties on demand over time. However, at pres...

  • Article
  • Open Access
6 Citations
2,903 Views
23 Pages

Retest effects refer to performance improvements in a final test by completing previous tests with the same or similar testing materials. Improvements in test-related skills and/or increasing familiarity with the stimulus materials are considered sou...

  • Article
  • Open Access
1 Citations
2,369 Views
17 Pages

Development and Validation of an IoT Neurostimulator for the Treatment of Neurogenic Bladder

  • Luana Cecilia Farache Lemos Leal,
  • Luiz Henrique Bertucci Borges,
  • Maria Eduarda Franklin da Costa De Paula,
  • Lilian Lira Lisboa and
  • André Felipe Oliveira de Azevedo Dantas

20 November 2023

Neurogenic bladder is a dysfunction in the lower urinary tract due to damage to the nervous system. One of the treatments that has shown important results is transcutaneous neuromodulation. The neuromodulation equipment available on the market does n...

  • Review
  • Open Access
61 Citations
5,369 Views
15 Pages

20 June 2022

Bone defects, as one of the most urgent problems in the orthopedic clinic, have attracted much attention from the biomedical community and society. Hydrogels have been widely used in the biomedical field for tissue engineering research because of the...

  • Review
  • Open Access
50 Citations
12,153 Views
28 Pages

On-Chip Integrated Photonic Devices Based on Phase Change Materials

  • Muhammad Shemyal Nisar,
  • Xing Yang,
  • Liangjun Lu,
  • Jianping Chen and
  • Linjie Zhou

Phase change materials present a unique type of materials that drastically change their electrical and optical properties on the introduction of an external electrical or optical stimulus. Although these materials have been around for some decades, t...

  • Review
  • Open Access
8 Citations
3,179 Views
14 Pages

10 December 2021

Advances in cell and tissue therapies are slow to be implemented in the clinic due to the limited standardization of safety and quality control techniques. Current approaches for monitoring cell and tissue manufacturing processes are time and labor i...

  • Article
  • Open Access
5 Citations
2,170 Views
11 Pages

H-Bonding Room Temperature Phosphorescence Materials via Facile Preparation for Water-Stimulated Photoluminescent Ink

  • Lingyun Lou,
  • Tianqi Xu,
  • Yuzhan Li,
  • Changli Zhang,
  • Bochun Wang,
  • Xusheng Zhang,
  • Hean Zhang,
  • Yuting Qiu,
  • Junyan Yang and
  • Zhou Yang
  • + 2 authors

1 October 2022

Pure organic room-temperature phosphorescence (RTP) materials built upon noncovalent interactions have attracted much attention because of their high efficiency, long lifetime, and stimulus-responsive behavior. However, there are limited reports of n...

  • Article
  • Open Access
7 Citations
2,469 Views
16 Pages

Hand and Foot Selection in Mental Body Rotations Involves Motor-Cognitive Interactions

  • Stephan Frederic Dahm,
  • Emiko J. Muraki and
  • Penny M. Pexman

4 November 2022

Action imagery involves the mental representation of an action without overt execution, and can contribute to perspective taking, such as that required for left-right judgments in mental body rotation tasks. It has been shown that perspective (back v...

  • Article
  • Open Access
20 Citations
4,102 Views
17 Pages

Modulation of the Lower Critical Solution Temperature of Thermoresponsive Poly(N-vinylcaprolactam) Utilizing Hydrophilic and Hydrophobic Monomers

  • Elaine Halligan,
  • Shuo Zhuo,
  • Declan Mary Colbert,
  • Mohamad Alsaadi,
  • Billy Shu Hieng Tie,
  • Gilberto S. N. Bezerra,
  • Gavin Keane and
  • Luke M. Geever

23 March 2023

Four-dimensional printing is primarily based on the concept of 3D printing technology. However, it requires additional stimulus and stimulus-responsive materials. Poly-N-vinylcaprolactam is a temperature-sensitive polymer. Unique characteristics of p...

  • Review
  • Open Access
55 Citations
8,351 Views
21 Pages

19 June 2019

In the last half-century, the development of biodegradable polyesters for biomedical applications has advanced significantly. Biodegradable polyester materials containing external stimuli-sensitive linkages are favored in the development of therapeut...

  • Article
  • Open Access
26 Citations
5,199 Views
10 Pages

10 December 2018

A new tetraphenylethylene (TPE) functionalized 1,4-dihydropyrrolo[3,2-b]pyrrole derivative (APPTPECN) was synthesized with obvious aggregation-induced emission (AIE) active by simple synthetic method. APPTPECN exhibited reversible mechanofluorochromi...

  • Article
  • Open Access
9 Citations
4,588 Views
10 Pages

Complementary Color Tuning by HCl via Phosphorescence-to-Fluorescence Conversion on Insulated Metallopolymer Film and Its Light-Induced Acceleration

  • Shunichi Kaneko,
  • Hiroshi Masai,
  • Takuya Yokoyama,
  • Maning Liu,
  • Yasuhiro Tachibana,
  • Tetsuaki Fujihara,
  • Yasushi Tsuji and
  • Jun Terao

20 January 2020

An insulated metallopolymer that undergoes phosphorescence-to-fluorescence conversion between complementary colors by an acid-stimulus is proposed as a color-tunable material. A Pt-based phosphorescent metallopolymer, where the conjugated polymeric b...

  • Article
  • Open Access
11 Citations
7,070 Views
16 Pages

Increased X-ray Visualization of Shape Memory Polymer Foams by Chemical Incorporation of Iodine Motifs

  • Landon D. Nash,
  • Mary Beth Browning Monroe,
  • Yong-Hong Ding,
  • Kendal P. Ezell,
  • Anthony J. Boyle,
  • Ramanathan Kadirvel,
  • David F. Kallmes and
  • Duncan J. Maitland

20 August 2017

Shape memory polymers can be programmed into a secondary geometry and recovered to their primary geometry with the application of a controlled stimulus. Porous shape memory polymer foam scaffolds that respond to body temperature show particular promi...

  • Review
  • Open Access
62 Citations
8,788 Views
29 Pages

Advances in Cellulose-Based Hydrogels for Biomedical Engineering: A Review Summary

  • Pengfei Zou,
  • Jiaxin Yao,
  • Ya-Nan Cui,
  • Te Zhao,
  • Junwei Che,
  • Meiyan Yang,
  • Zhiping Li and
  • Chunsheng Gao

8 June 2022

In recent years, hydrogel-based research in biomedical engineering has attracted more attention. Cellulose-based hydrogels have become a research hotspot in the field of functional materials because of their outstanding characteristics such as excell...

  • Article
  • Open Access
6 Citations
7,266 Views
15 Pages

An Efficient, Short Stimulus PANC-1 Cancer Cell Ablation and Electrothermal Therapy Driven by Hydrophobic Interactions

  • Maria P. Meivita,
  • Denise Lee,
  • J Shamita Naikar,
  • Shao-Xiang Go,
  • Wey Chyi Teoh,
  • Yaw Sing Tan,
  • Natasa Bajalovic and
  • Desmond K. Loke

Promising results in clinical studies have been demonstrated by the utilization of electrothermal agents (ETAs) in cancer therapy. However, a difficulty arises from the balance between facilitating the degradation of ETAs, and at the same time, incre...

  • Review
  • Open Access
49 Citations
5,541 Views
23 Pages

Chitosan-Based Nano-Smart Drug Delivery System in Breast Cancer Therapy

  • Yedi Herdiana,
  • Nasrul Wathoni,
  • Dolih Gozali,
  • Shaharum Shamsuddin and
  • Muchtaridi Muchtaridi

Despite recent advances, cancer remains the primary killer on a global scale. Numerous forms of research have been conducted to discover novel and efficient anticancer medications. The complexity of breast cancer is a major challenge which is coupled...

  • Article
  • Open Access
1,575 Views
21 Pages

Fear Generalization Towards a Stimulus and Context and the Impact of Attention Bias

  • Haote Fu,
  • Keying Luo,
  • Zishan Wu,
  • Ruiqi Diao and
  • Xifu Zheng

20 December 2024

Fear overgeneralization is a prevalent clinical symptom of anxiety disorders. Various research studies have demonstrated that attention plays a crucial role in fear generalization. Moreover, fear is not only generalized to the stimulus, but individua...

  • Review
  • Open Access
6 Citations
4,773 Views
28 Pages

Advances in the Structural Strategies of the Self-Assembly of Photoresponsive Supramolecular Systems

  • Vivian J. Santamaria-Garcia,
  • Domingo R. Flores-Hernandez,
  • Flavio F. Contreras-Torres,
  • Rodrigo Cué-Sampedro and
  • José Antonio Sánchez-Fernández

Photosensitive supramolecular systems have garnered attention due to their potential to catalyze highly specific tasks through structural changes triggered by a light stimulus. The tunability of their chemical structure and charge transfer properties...

  • Review
  • Open Access
89 Citations
15,311 Views
32 Pages

4D Printing: Materials, Technologies, and Future Applications in the Biomedical Field

  • Ankur Bajpai,
  • Anna Baigent,
  • Sakshika Raghav,
  • Conchúr Ó. Brádaigh,
  • Vasileios Koutsos and
  • Norbert Radacsi

19 December 2020

4D printing can be defined as the fabrication of structures using smart materials that allow the final object to change its shape, properties, or function in response to an external stimulus such as light, heat, or moisture. The available technologie...

  • Article
  • Open Access
7 Citations
7,128 Views
12 Pages

Application of Sub-Micrometer Vibrations to Mitigate Bacterial Adhesion

  • Will R. Paces,
  • Hal R. Holmes,
  • Eli Vlaisavljevich,
  • Katherine L. Snyder,
  • Ee Lim Tan,
  • Rupak M. Rajachar and
  • Keat Ghee Ong

As a prominent concern regarding implantable devices, eliminating the threat of opportunistic bacterial infection represents a significant benefit to both patient health and device function. Current treatment options focus on chemical approaches to n...

  • Review
  • Open Access
51 Citations
8,635 Views
15 Pages

4D Textiles Made by Additive Manufacturing on Pre-Stressed Textiles—An Overview

  • Hannah Carlotta Koch,
  • David Schmelzeisen and
  • Thomas Gries

10 February 2021

Four-dimensional textiles are textiles that can change shape or function over time by the influence of a stimulus, mainly force and heat. In this review, the focus is on 4D textiles made by additive manufacturing which is built on the concept of 4D p...

  • Article
  • Open Access
15 Citations
2,587 Views
16 Pages

13 January 2022

This paper is aimed at investigating the use of polyurethane mats, usually used as ballast mats, for residential building purposes. Ballast mats have features that may improve the vibroacoustic comfort in residential rooms. Their strength is certainl...

  • Review
  • Open Access
10 Citations
5,837 Views
29 Pages

Controlled Stimulus-Responsive Delivery Systems for Osteoarthritis Treatment

  • Qianwen Ye,
  • Mingshuo Zhang,
  • Shuyue Li,
  • Wenyue Liu,
  • Chunming Xu,
  • Yumei Li and
  • Renjian Xie

2 November 2024

Osteoarthritis (OA), a common and disabling degenerative joint disease, affects millions of people worldwide and imposes a considerable burden on patients and society due to its high prevalence and economic costs. The pathogenesis of OA is closely re...

  • Review
  • Open Access
67 Citations
9,174 Views
18 Pages

26 March 2012

Responsive polymers attached to the inside of nano/micro-pores have attracted great interest owing to the prospect of designing flow-control devices and signal responsive delivery systems. An intriguing possibility involves functionalizing nanoporous...

  • Review
  • Open Access
36 Citations
8,801 Views
24 Pages

24 November 2015

Embedding of fibers in materials has attracted serious attention from researchers and has become a new research trend. Such material structures are usually termed “smart” or more recently “nervous”. Materials can have the capability of sensing and re...

  • Article
  • Open Access
3 Citations
3,335 Views
12 Pages

[2+2] Cyclo-Addition Reactions for Efficient Polymerization on a HOPG Surface at Ambient Conditions

  • Lihao Guan,
  • Frank Palmino,
  • Jean-Christophe Lacroix,
  • Frédéric Chérioux and
  • Xiaonan Sun

13 April 2022

Polymers obtained by on-surface chemistry have emerged as a class of promising materials. Here, we propose a new strategy to obtain self-assembled 1D polymers by using photochemical [2+2] cyclo-addition or by using a mild thermal annealing. All nanos...

  • Review
  • Open Access
48 Citations
9,015 Views
22 Pages

Contactless Manipulation of Soft Robots

  • Jae Gwang Kim,
  • Jeong Eun Park,
  • Sukyoung Won,
  • Jisoo Jeon and
  • Jeong Jae Wie

20 September 2019

In recent years, jointless soft robots have demonstrated various curvilinear motions unlike conventional robotic systems requiring complex mechanical joints and electrical design principles. The materials employed to construct soft robots are mainly...

  • Review
  • Open Access
143 Citations
20,677 Views
27 Pages

2 January 2013

“Surrounding matters” is a phrase that has become more significant in recent times when discussing polymeric materials. Although regular polymers do respond to external stimuli like softening of material at higher temperatures, that response is gradu...

  • Article
  • Open Access
11 Citations
3,943 Views
18 Pages

Shape-Memory Composites Based on Ionic Elastomers

  • Antonio González-Jiménez,
  • Pilar Bernal-Ortega,
  • Fernando M. Salamanca and
  • Juan L. Valentin

18 March 2022

Shape-memory polymers tend to present rigid behavior at ambient temperature, being unable to deform in this state. To obtain soft shape-memory elastomers, composites based on a commercial rubber crosslinked by both ionic and covalent bonds were devel...

  • Review
  • Open Access
5 Citations
5,406 Views
16 Pages

Design of Cell-Specific Targeting Peptides for Cancer Therapy

  • Xiaoyong Chen,
  • Di Wang,
  • Yun-Bao Jiang and
  • Tao Jiang

27 July 2024

The landscape of cancer therapy has gained major impetus through the development of materials capable of selectively targeting cancer cells while sparing normal cells. Synthetic peptides are appealing as scaffolds for the creation of such materials....

  • Review
  • Open Access
13 Citations
4,840 Views
16 Pages

Symmetry Breaking and Photomechanical Behavior of Photochromic Organic Crystals

  • Daichi Kitagawa,
  • Christopher J. Bardeen and
  • Seiya Kobatake

9 September 2020

Photomechanical materials exhibit mechanical motion in response to light as an external stimulus. They have attracted much attention because they can convert light energy directly to mechanical energy, and their motions can be controlled without any...

  • Feature Paper
  • Review
  • Open Access
41 Citations
9,566 Views
25 Pages

Engineering Organ-on-a-Chip to Accelerate Translational Research

  • Jihoon Ko,
  • Dohyun Park,
  • Somin Lee,
  • Burcu Gumuscu and
  • Noo Li Jeon

28 July 2022

We guide the use of organ-on-chip technology in tissue engineering applications. Organ-on-chip technology is a form of microengineered cell culture platform that elaborates the in-vivo like organ or tissue microenvironments. The organ-on-chip platfor...

  • Review
  • Open Access
70 Citations
9,771 Views
23 Pages

The Benefits of Smart Nanoparticles in Dental Applications

  • Silvia Vasiliu,
  • Stefania Racovita,
  • Ionela Aurica Gugoasa,
  • Maria-Andreea Lungan,
  • Marcel Popa and
  • Jacques Desbrieres

Dentistry, as a branch of medicine, has undergone continuous evolution over time. The scientific world has focused its attention on the development of new methods and materials with improved properties that meet the needs of patients. For this purpos...

  • Article
  • Open Access
5 Citations
1,519 Views
12 Pages

Influence of Infill Patterns on the Shape Memory Effect of Cold-Programmed Additively Manufactured PLA

  • Vladimir Barrera-Quintero,
  • Erasmo Correa-Gómez,
  • Alberto Caballero-Ruiz and
  • Leopoldo Ruiz-Huerta

29 August 2024

In four-dimensional additive manufacturing (4DAM), specific external stimuli are applied in conjunction with additive manufacturing technologies. This combination allows the development of tailored stimuli-responsive properties in various materials,...

  • Article
  • Open Access
1 Citations
1,378 Views
7 Pages

5 October 2012

Background and Objective. The purpose of sensory adaptation of the visual system is to adjust sensitivity of the photoreceptors to optimize the dynamic range of response of the visual system. It has been shown in numerous research papers that chromat...

  • Article
  • Open Access
2 Citations
1,159 Views
5 Pages

Changes of electrophysiological parameters in patients with atrial flutter

  • Diana Žaliaduonytė-Pekšienė,
  • Tomas Kazakevičius,
  • Vytautas Zabiela,
  • Vytautas Šileikis,
  • Remigijus Vaičiulis,
  • Martynas Virketis and
  • Aras Puodžiukynas

8 August 2007

Objectives. The aim of the study was to study some anatomic and electrophysiological features of the right atrium, related to the presence of atrial flutter. Materials and methods. A total 23 patients with type I atrial flutter and 22 patients witho...

  • Review
  • Open Access
28 Citations
10,519 Views
29 Pages

Advances in Smart-Response Hydrogels for Skin Wound Repair

  • Yinuo Fan,
  • Han Wang,
  • Chunxiao Wang,
  • Yuanhao Xing,
  • Shuying Liu,
  • Linhan Feng,
  • Xinyu Zhang and
  • Jingdi Chen

5 October 2024

Hydrogels have emerged as promising candidates for biomedical applications, especially in the treatment of skin wounds, as a result of their unique structural properties, highly tunable physicochemical properties, and excellent biocompatibility. The...

  • Article
  • Open Access
3 Citations
2,991 Views
21 Pages

18 November 2022

Acoustic-phonetic speech training mitigates confusion between consonants and improves phoneme identification in noise. A novel training paradigm addressed two principles of perceptual learning. First, training benefits are often specific to the train...

  • Article
  • Open Access
10 Citations
3,955 Views
18 Pages

19 September 2024

The rapid development of rural tourism has placed significant pressure on the rural environment, and relying solely on the government and market forces is insufficient for effective governance. It is urgent to integrate endogenous rural forces into e...

  • Feature Paper
  • Review
  • Open Access
51 Citations
7,889 Views
15 Pages

2 November 2019

Ultrasonic agitation is an external stimulus, rapidly developed in recent years in the atom transfer radical polymerization (ATRP) approach. This review presents the current state-of-the-art in the application of ultrasound in ATRP, including an init...

  • Feature Paper
  • Review
  • Open Access
185 Citations
21,913 Views
33 Pages

15 February 2020

Shape memory polymers (SMPs) are smart materials capable of changing their shapes in a predefined manner under a proper applied stimulus and have gained considerable interest in several application fields. Particularly, two-way and multiple-way SMPs...

  • Review
  • Open Access
15 Citations
4,814 Views
18 Pages

Interface Chirality: From Biological Effects to Biomedical Applications

  • Liting Guo,
  • Yanqiu Guo,
  • Rui Wang,
  • Jie Feng,
  • Nannan Shao,
  • Xiaolin Zhou and
  • Yunlong Zhou

25 July 2023

Chiral surface is a critical mediator that significantly impacts interaction with biological systems on regulating cell behavior. To better understand how the properties of interfacial Chirality affect cell behavior and address the limitations of chi...

  • Review
  • Open Access
8 Citations
2,955 Views
17 Pages

15 September 2023

Photo-controlled self-assembly of nanoparticles (NPs) is an advanced and promising approach to address a series of material issues from the molecular level to the nano/micro scale, owing to the fact that light stimulus is typically precise and rapid,...

  • Review
  • Open Access
30 Citations
10,197 Views
30 Pages

Dynamic Covalent Bond-Based Polymer Chains Operating Reversibly with Temperature Changes

  • Sojeong Roh,
  • Yeonjeong Nam,
  • My Thi Ngoc Nguyen,
  • Jae-Hee Han and
  • Jun Seop Lee

10 July 2024

Dynamic bonds can facilitate reversible formation and dissociation of connections in response to external stimuli, endowing materials with shape memory and self-healing capabilities. Temperature is an external stimulus that can be easily controlled t...

  • Review
  • Open Access
13 Citations
3,857 Views
20 Pages

16 May 2025

Hydrogels are pivotal in advanced materials, driving innovations in medical fields, such as targeted drug delivery, regenerative medicine, and skin repair. This systematic review explores the transformative impact of in-silico design on hydrogel deve...

  • Feature Paper
  • Article
  • Open Access
31 Citations
4,357 Views
16 Pages

The Multidirectional Auxeticity and Negative Linear Compressibility of a 3D Mechanical Metamaterial

  • Krzysztof K. Dudek,
  • Daphne Attard,
  • Ruben Gatt,
  • James N. Grima-Cornish and
  • Joseph N. Grima

10 May 2020

In this work, through the use of a theoretical model, we analyse the potential of a specific three-dimensional mechanical metamaterial composed of arrowhead-like structural units to exhibit a negative Poisson’s ratio for an arbitrary loading di...

  • Review
  • Open Access
2 Citations
2,066 Views
25 Pages

Novel Lead Halide Perovskite and Copper Iodide Materials for Fluorescence Sensing of Oxygen

  • Jingwen Jin,
  • Yaning Huang,
  • Chen Zhang,
  • Li Zhang,
  • Shaoxing Jiang and
  • Xi Chen

21 February 2025

The most commonly used optical oxygen sensing materials are phosphorescent molecules and functionalized nanocrystals. Many exploration studies on oxygen sensing have been carried out using the fluorescence or phosphorescence of semiconductor nanomate...

  • Review
  • Open Access
58 Citations
8,390 Views
18 Pages

20 October 2021

In recent years, great progress has been made in the field of energy harvesting to satisfy increasing needs for portable, sustainable, and renewable energy. Among piezoelectric materials, poly(vinylidene fluoride) (PVDF) and its copolymers are the mo...

of 8