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Toxics, Volume 11, Issue 12

2023 December - 82 articles

Cover Story: Per- and poly-fluoroalkyl substances (PFAS), encompassing legacy compounds such as PFOS, PFOA, PFNA, and PFHxS, are known for inducing hepatotoxicity. Emerging alternatives and a byproduct (HFPO-DA, HFPO4, HFPO-TA, F-53B, 6:2 FTSA, 6:2 FTCA, Nafion BP2) raise environmental concerns. In this comparative hepatic-toxicogenomics study, we found significant molecular overlap between legacy and alternative PFAS, with only Nafion BP2, 6:2 FTSA, and 6:2 FTCA showing limited PPARα activation. Predictive biomarkers indicated CAR activation by most PFAS, while specific suppression and activation patterns were observed in STAT5b, NRF2, and SREBP. No clear correlation was apparent with carbon chain length, head group type, or ether linkages, emphasizing the need for comprehensive risk assessment. View this paper
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Articles (82)

  • Article
  • Open Access
3 Citations
3,253 Views
12 Pages

Ultrastructural Changes in the Midgut of Brazilian Native Stingless Bee Melipona scutellaris Exposed to Fungicide Pyraclostrobin

  • Caio E. C. Domingues,
  • Lais V. B. Inoue,
  • Aleš Gregorc,
  • Leticia S. Ansaloni,
  • Osmar Malaspina and
  • Elaine C. Mathias da Silva

18 December 2023

Melipona scutellaris is a Brazilian stingless bee that is important for pollinating wild flora and agriculture crops. Fungicides have been widely used in agriculture, and floral residues can affect forager bees. The goal of our study was to evaluate...

(This article belongs to the Special Issue Impacts of Agrochemicals: Environmental Fate, Ecotoxicology, Risk Assessment, and Remediation)
  • Article
  • Open Access
12 Citations
2,730 Views
18 Pages

Structural Malformations in the Neonatal Rat Brain Accompany Developmental Exposure to Ammonium Perchlorate

  • Mary E. Gilbert,
  • Katherine L. O’Shaughnessy,
  • Kiersten S. Bell and
  • Jermaine L. Ford

18 December 2023

Environmental contaminants are often flagged as thyroid system disruptors due to their actions to reduce serum thyroxine (T4) in rodent models. The presence of a periventricular heterotopia (PVH), a brain malformation resulting from T4 insufficiency,...

(This article belongs to the Section Neurotoxicity)
  • Article
  • Open Access
8 Citations
3,083 Views
16 Pages

TGF-β Regulates m6A RNA Methylation after PM2.5 Exposure

  • Tingting Wu,
  • Bingqian Liu,
  • Yongjie Wei and
  • Zhigang Li

16 December 2023

PM2.5 exposure leads to a variety of respiratory diseases, including pulmonary fibrosis, metastatic lung cancer, etc. Exposure to PM2.5 results in the alteration of epigenetic modification. M6A RNA methylation is an essential epigenetic modification...

(This article belongs to the Section Exposome Analysis and Risk Assessment)
  • Article
  • Open Access
6 Citations
3,792 Views
16 Pages

Characteristics of Soil Arsenic Contamination and the Potential of Pioneer Plants for Arsenic Remediation in Gold Mine Tailings

  • Lei Han,
  • Yunmeng Zhai,
  • Rui Chen,
  • Yamin Fan,
  • Zhao Liu,
  • Yonghua Zhao,
  • Risheng Li and
  • Longfei Xia

16 December 2023

Arsenic (As) contamination of gold mine tailings poses major threats to the natural environment and human health, necessitating adequate management measures. To investigate the soil As contamination level and the potential of pioneer plants for As re...

(This article belongs to the Special Issue Biochemical Remediation and Ecological Risk Assessment of Heavy Metal Contaminated Soil)
  • Article
  • Open Access
6 Citations
3,448 Views
16 Pages

Distribution, Transfer, and Health Risk of Organochlorine Pesticides in Soil and Water of the Huangshui River Basin

  • Ruyue Yu,
  • Yang Zhou,
  • Shengxian Xu,
  • Jing Jing,
  • Hongyan Zhang and
  • Yuanfang Huang

15 December 2023

The potential negative impacts of organochlorine pesticides on the environment and human health continue to receive attention. In order to study the spatial distribution characteristics of organochlorine pesticides in the inland alpine region, resear...

(This article belongs to the Section Ecotoxicology)
  • Article
  • Open Access
6 Citations
2,976 Views
23 Pages

15 December 2023

Hundreds of thousands of people living along the Yatsushiro Sea coast have been exposed to methylmercury from the contaminated water of the Chisso factory in Minamata. The most common neurological disorder caused by methylmercury is somatosensory dis...

(This article belongs to the Special Issue Feature Papers in Environmental Epidemiology)
  • Article
  • Open Access
1 Citations
2,561 Views
16 Pages

Enzymatic Stress Responses of Coreius guichenoti to Microplastics with Different Particle Sizes

  • Wenqiong Wu,
  • Junqiang Qiu,
  • Yue Lin,
  • Xike Li,
  • Wenjuan Li,
  • Keyi Ma,
  • Yuanliang Duan and
  • Yuanshuai Fu

15 December 2023

The wild population resources of Coreius guichenoti have sharply declined in recent decades, and any negative factors may have a significant impact on their survival. In this study, the enzymatic stress responses of C. guichenoti to 25 and 48 μm p...

(This article belongs to the Section Emerging Contaminants)
  • Feature Paper
  • Article
  • Open Access
12 Citations
4,033 Views
12 Pages

14 December 2023

Studies comparing the ocular toxicity potential between legacy and alternative PFAS are lacking. To address this research gap, zebrafish larvae were exposed to both legacy PFAS (i.e., perfluorooctanesulfonic acid [PFOS] and perfluorooctanoic acid [PF...

(This article belongs to the Special Issue Environmental Pollutants Toxicity Mechanism and Safety Testing: Zebrafish as a Model Organism)
  • Article
  • Open Access
8 Citations
2,804 Views
15 Pages

First Report of the Joint Exposure to Glyphosate and Glufosinate of a Male Population in the Province of Córdoba (Argentina)

  • Iohanna Filippi,
  • Rocío I. Bonansea,
  • Mariana Butinof,
  • Ricardo A. Fernández,
  • Marta Llorca,
  • Marinella Farré,
  • Sonia E. Muñoz and
  • María V. Amé

14 December 2023

Despite potential health implications, data on the presence of Glyphosate (GLY) and other non-GLY herbicides in human matrices remain scarce. This study aimed to develop a simple and cost-effective methodology for detecting and quantifying GLY, its p...

(This article belongs to the Special Issue The 10th Anniversary of Toxics)
  • Article
  • Open Access
16 Citations
4,443 Views
14 Pages

Reduction of Outdoor and Indoor PM2.5 Source Contributions via Portable Air Filtration Systems in a Senior Residential Facility in Detroit, Michigan

  • Zachary M. Klaver,
  • Ryan C. Crane,
  • Rosemary A. Ziemba,
  • Robert L. Bard,
  • Sara D. Adar,
  • Robert D. Brook and
  • Masako Morishita

14 December 2023

Background: The Reducing Air Pollution in Detroit Intervention Study (RAPIDS) was designed to evaluate cardiovascular health benefits and personal fine particulate matter (particulate matter < 2.5 μm in diameter, PM2.5) exposure reductions via...

(This article belongs to the Section Air Pollution and Health)
  • Article
  • Open Access
28 Citations
5,428 Views
17 Pages

Health Risk Assessment of Heavy Metals in Indoor Household Dust in Urban and Rural Areas of Chiang Mai and Lamphun Provinces, Thailand

  • Kawinwut Somsunun,
  • Tippawan Prapamontol,
  • Todsabhorn Kuanpan,
  • Teetawat Santijitpakdee,
  • Kanyapak Kohsuwan,
  • Natwasan Jeytawan and
  • Nathaporn Thongjan

14 December 2023

Indoor exposure to heavy metals poses human health risks worldwide, but study reports from Thailand are still limited, particularly in rural and urban areas. We measured the heavy metals in a hundred indoor household dust samples collected from urban...

(This article belongs to the Special Issue Potentially Toxic Elements Pollution in Urban and Suburban Environments II)
  • Feature Paper
  • Systematic Review
  • Open Access
7 Citations
8,188 Views
27 Pages

Freshwater Lacustrine Zooplankton and Microplastic: An Issue to Be Still Explored

  • Jassica Lawrence,
  • Carlotta Santolini,
  • Gilberto Binda,
  • Stefano Carnati,
  • Ginevra Boldrocchi,
  • Andrea Pozzi and
  • Roberta Bettinetti

13 December 2023

Lakes are essentially interlinked to humans as they provide water for drinking, agriculture, industrial and domestic purposes. The upsurge of plastic usage, its persistence, and potential detrimental effects on organisms cause impacts on the trophic...

(This article belongs to the Special Issue Ecotoxicological Effects of Emerging Contaminants on Aquatic Species)
  • Article
  • Open Access
4 Citations
4,536 Views
13 Pages

Method Validation for Quantification of PFOS and PFOA in Human Plasma and a Pilot Study in Blood Donors from Thai Red Cross Society

  • Teerapong Lertassavakorn,
  • Nanthanit Pholphana,
  • Nuchanart Rangkadilok,
  • Tawit Suriyo,
  • Punthip Teeyapant and
  • Jutamaad Satayavivad

13 December 2023

Information regarding per- and polyfluorinated substances concentrations in biological samples from the Thai population was still lacking. A sensitive bioanalytical method was developed and validated for the quantification of perfluorooctane sulfonic...

(This article belongs to the Section Exposome Analysis and Risk Assessment)
  • Article
  • Open Access
10 Citations
3,374 Views
17 Pages

Degradation of Ciprofloxacin in Water by Magnetic-Graphene-Oxide-Activated Peroxymonosulfate

  • Xiaoping Wang,
  • Yulan Li,
  • Jiayuan Qin,
  • Ping Pan,
  • Tianqing Shao,
  • Xue Long and
  • Debin Jiang

13 December 2023

Antibiotics are extensively applied in the pharmaceutical industry, while posing a tremendous hazard to the ecosystem and human health. In this study, the degradation performance of ciprofloxacin (CIP), one of the typical contaminants of antibiotics,...

(This article belongs to the Special Issue Editorial Board Members’ Collection Series: Advanced Oxidation Processes of Organic Contaminants)
  • Review
  • Open Access
10 Citations
5,482 Views
39 Pages

12 December 2023

A growing body of literature has attempted to characterize how traffic-related air pollution (TRAP) affects molecular and subclinical biological processes in ways that could lead to cardiorespiratory disease. To provide a streamlined synthesis of wha...

(This article belongs to the Section Air Pollution and Health)
  • Article
  • Open Access
9 Citations
4,713 Views
16 Pages

Metals in Cow Milk and Soy Beverages: Is There a Concern?

  • Vanda Lopes Andrade,
  • Iolanda Ribeiro,
  • A. P. Marreilha dos Santos,
  • Michael Aschner and
  • Maria Luisa Mateus

11 December 2023

Nowadays, there is an increased consumption of plant-based protein beverages like soy beverages (SBs) as substitutes for cow milk (CM). Both accumulate toxic metals like lead (Pb), cadmium (Cd), and manganese (Mn), which, although essential, are neur...

(This article belongs to the Special Issue Environmental Exposure to Toxic Chemicals and Human Health II)
  • Review
  • Open Access
17 Citations
9,720 Views
12 Pages

11 December 2023

Xylazine abuse is emerging globally, while the identification of xylazine lethal cases poses a great challenge in clinical and forensic practice. The non-specific symptoms delay the diagnosis and treatment of xylazine poisoning, the pathological chan...

(This article belongs to the Special Issue Feature Papers in Drug Toxicity)
  • Review
  • Open Access
74 Citations
13,447 Views
23 Pages

Radiation-Induced Intestinal Injury: Injury Mechanism and Potential Treatment Strategies

  • Qianying Lu,
  • Yangfan Liang,
  • Sijia Tian,
  • Jie Jin,
  • Yanmei Zhao and
  • Haojun Fan

10 December 2023

Radiation-induced intestinal injury (RIII) is one of the most common intestinal complications caused by radiotherapy for pelvic and abdominal tumors and it seriously affects the quality of life of patients. However, the treatment of acute RIII is ess...

(This article belongs to the Section Exposome Analysis and Risk Assessment)
  • Article
  • Open Access
4 Citations
2,674 Views
15 Pages

10 December 2023

The low-dose toxicity of chloride and nitrate salts of three lanthanides (La, Ce and Nd) was tested on six microfungal species. Five of them (Geomyces vinaceus, Aspergillus niveoglaucus, Pseudogymnoascus pannorum, Penicillium simplicissimum and Umbel...

(This article belongs to the Section Hormesis in Toxicology)
  • Article
  • Open Access
8 Citations
3,652 Views
11 Pages

Impact of Cadmium Contamination on Fertilizer Value and Associated Health Risks in Different Soil Types Following Anaerobic Digestate Application

  • Ghulam Mustafa Shah,
  • Umer Farooq,
  • Zunaira Shabbir,
  • Jianbin Guo,
  • Renjie Dong,
  • Hafiz Faiq Bakhat,
  • Muhammad Wakeel,
  • Ayesha Siddique and
  • Naeem Shahid

10 December 2023

Cadmium (Cd) contamination in the soil potentially hampers microbial biomass and adversely affects their services such as decomposition and mineralization of organic matter. It can reduce nitrogen (N) metabolism and consequently affect plant growth a...

(This article belongs to the Section Toxicity Reduction and Environmental Remediation)
  • Case Report
  • Open Access
3 Citations
2,700 Views
9 Pages

Elevated Lead, Nickel, and Bismuth Levels in the Peritoneal Fluid of a Peritoneal Endometriosis Patient without Toxic Habits or Occupational Exposure following a Vegetarian Diet

  • Andrea López-Botella,
  • María José Gómez-Torres,
  • Raquel Sánchez,
  • José-Luis Todolí-Torró,
  • Irene Velasco and
  • Maribel Acién

10 December 2023

Potentially toxic elements (PTEs), found as environmental contaminants, have been related to endometriosis disease. In this context, the peritoneal fluid (PF) matrix has been poorly studied despite its importance. PF is the environment in which endom...

(This article belongs to the Special Issue 10th Anniversary of Toxics: Women's Special Issue Series)
  • Feature Paper
  • Article
  • Open Access
5 Citations
2,831 Views
14 Pages

9 December 2023

The elements in blood normally reflect the levels in prey, indicating a recent exposure. Laughing gulls (Leucophaes atricilla) eat mainly horseshoe crab eggs (Limulus polyphemus) in the spring in Delaware Bay, New Jersey. The levels of arsenic (As),...

(This article belongs to the Special Issue 10th Anniversary of Toxics: Women's Special Issue Series)
  • Article
  • Open Access
13 Citations
3,864 Views
21 Pages

8 December 2023

Research on soil heavy metal(loid) pollution and health risk assessment is extensive, but a notable gap exists in systematically examining uncertainty in this process. We employ the Nemerow index, the health risk assessment model, and the geographic...

(This article belongs to the Section Metals and Radioactive Substances)
  • Article
  • Open Access
6 Citations
3,414 Views
21 Pages

Ecotoxicology of Polymetallic Nodule Seabed Mining: The Effects of Cobalt and Nickel on Phytoplankton Growth and Pigment Concentration

  • Rimei Ou,
  • Hao Huang,
  • Xuebao He,
  • Shuangshuang Lin,
  • Danyun Ou,
  • Weiwen Li,
  • Jinli Qiu and
  • Lei Wang

8 December 2023

In order to improve the understanding of the environmental impacts of polymetallic nodule mining, ecotoxicological studies were conducted on the growth of model phytoplankton species Skeletonema costatum and Prorocentrum donghaiense using cobalt and...

(This article belongs to the Topic Health Risk Assessment of the Trace and Macro Elements)
  • Article
  • Open Access
11 Citations
4,545 Views
16 Pages

Exploring Serum Biomarkers for Neuropathic Pain in Rat Models of Chemotherapy-Induced Peripheral Neuropathy: A Comparative Pilot Study with Oxaliplatin, Paclitaxel, Bortezomib, and Vincristine

  • David Balayssac,
  • Julie Durif,
  • Céline Lambert,
  • Cristelle Dalbos,
  • Eric Chapuy,
  • Monique Etienne,
  • Claire Demiot,
  • Jérôme Busserolles,
  • Vincent Martin and
  • Vincent Sapin

8 December 2023

Blood biomarkers, including neurofilament light chain (NfL), have garnered attention as potential indicators for chemotherapy-induced peripheral neuropathy (CIPN), a dose-limiting adverse effect of neurotoxic anticancer drugs. However, no blood bioma...

(This article belongs to the Section Exposome Analysis and Risk Assessment)
  • Article
  • Open Access
2 Citations
2,586 Views
14 Pages

8 December 2023

In the present study, the developmental toxicity and endocrine-disrupting effects of fenpropathrin on Gobiocypris rarus during the early life stage were studied using a semi-static water exposure method. The results showed that the LOEC (lowest obser...

(This article belongs to the Topic Advances in Environmental Behaviors of Persistent Contaminants: Fate, Distribution, Risk, and Challenges)
  • Brief Report
  • Open Access
2 Citations
4,082 Views
15 Pages

Reduced Isocyanate Release Using a Waterproof, Resin-Based Cast Alternative Relative to Fiberglass Casts

  • Kristen Stefanescu,
  • Claire L. Timlin,
  • Ashley S. Moy and
  • Grzegorz Zapotoczny

8 December 2023

The effects of occupational isocyanate exposure range from asthma and contact dermatitis to neurotoxicity and cancer. Respiratory sensitization due to orthopedic cast application has been well documented. This study aims to compare the safety of stan...

(This article belongs to the Section Exposome Analysis and Risk Assessment)
  • Communication
  • Open Access
26 Citations
4,239 Views
14 Pages

Biodegradation Potential of C7-C10 Perfluorocarboxylic Acids and Data from the Genome of a New Strain of Pseudomonas mosselii 5(3)

  • Sergey Chetverikov,
  • Gaisar Hkudaygulov,
  • Danil Sharipov,
  • Sergey Starikov and
  • Darya Chetverikova

8 December 2023

The use of bacteria of the genus Pseudomonas—destructors of persistent pollutants for biotechnologies of environmental purification—is an interesting area of research. The aim of this work was to study the potential of Pseudomonas mo...

(This article belongs to the Special Issue Occurrence, Fate, Removal, and Effects of Per- and Polyfluoroalkyl Substances (PFASs))
  • Review
  • Open Access
19 Citations
10,437 Views
38 Pages

Invisible Hand behind Female Reproductive Disorders: Bisphenols, Recent Evidence and Future Perspectives

  • Xiaoyun Wu,
  • Yuchai Tian,
  • Huizhen Zhu,
  • Pengchong Xu,
  • Jiyue Zhang,
  • Yangcheng Hu,
  • Xiaotong Ji,
  • Ruifeng Yan,
  • Huifeng Yue and
  • Nan Sang

7 December 2023

Reproductive disorders are considered a global health problem influenced by physiological, genetic, environmental, and lifestyle factors. The increased exposure to bisphenols, a chemical used in large quantities for the production of polycarbonate pl...

(This article belongs to the Section Exposome Analysis and Risk Assessment)
  • Article
  • Open Access
10 Citations
3,035 Views
21 Pages

7 December 2023

This experiment was conducted to study the effects of Cyfluthrin (Cy) exposure on neurobehaviour, hippocampal tissue and synaptic plasticity in Wistar rats. First, it was found that high-dose Cy exposure could cause nerve injury, resulting in symptom...

(This article belongs to the Section Neurotoxicity)
  • Article
  • Open Access
1 Citations
2,761 Views
19 Pages

7 December 2023

Tobacco smoke contains between 7000 and 10,000 constituents, and only an evanescently low number of which have been identified, let alone been evaluated for their toxicity. Recently, the Food and Drug Administration has published a list of 93 chemica...

(This article belongs to the Section Reproductive and Developmental Toxicity)
  • Article
  • Open Access
6 Citations
2,480 Views
17 Pages

Probabilistic Risk Assessment of Heavy Metals in Mining Soils Based on Fractions: A Case Study in Southern Shaanxi, China

  • Lei Han,
  • Yamin Fan,
  • Rui Chen,
  • Yunmeng Zhai,
  • Zhao Liu,
  • Yonghua Zhao,
  • Risheng Li and
  • Longfei Xia

7 December 2023

With rapid economic development, soil heavy metal (HM) pollution has emerged as a global environmental concern. Because the toxicity of HMs differs dramatically among various fractions, risk assessments based on these fractions are of great significa...

(This article belongs to the Topic Advances in Environmental Behaviors of Persistent Contaminants: Fate, Distribution, Risk, and Challenges)
  • Article
  • Open Access
4 Citations
3,251 Views
40 Pages

Application of Machine Learning in Modeling the Relationship between Catchment Attributes and Instream Water Quality in Data-Scarce Regions

  • Miljan Kovačević,
  • Bahman Jabbarian Amiri,
  • Silva Lozančić,
  • Marijana Hadzima-Nyarko,
  • Dorin Radu and
  • Emmanuel Karlo Nyarko

7 December 2023

This research delves into the efficacy of machine learning models in predicting water quality parameters within a catchment area, focusing on unraveling the significance of individual input variables. In order to manage water quality, it is necessary...

(This article belongs to the Special Issue Advances in Water, Air and Soil Pollution Monitoring, Modeling and Restoration)
  • Article
  • Open Access
12 Citations
2,642 Views
19 Pages

7 December 2023

This study was aimed at investigating the pathogenesis of chronic obstructive pulmonary disease (COPD) caused by smoking—based on bioinformatics analysis and in vitro experimental evidence. The GEO, GEO2R, TargetScan, miRDB, miRWalk, DAVID, and...

(This article belongs to the Special Issue Health Risk and Toxicity Mechanism of Nanoparticles or Ultrafine Particles Inhalation)
  • Article
  • Open Access
13 Citations
2,962 Views
12 Pages

Toxicity of Titanium Dioxide–Cerium Oxide Nanocomposites to Zebrafish Embryos: A Preliminary Evaluation

  • Roberta Pecoraro,
  • Elena Maria Scalisi,
  • Stefania Indelicato,
  • Martina Contino,
  • Giuliana Coco,
  • Ilenia Stancanelli,
  • Fabiano Capparucci,
  • Roberto Fiorenza and
  • Maria Violetta Brundo

6 December 2023

The widespread use of metal nanoparticles in different fields has raised many doubts regarding their possible toxicity to living organisms and the accumulation and discharge of metals in fish species. Among these nanoparticles, titanium dioxide (TiO2...

(This article belongs to the Section Ecotoxicology)
  • Feature Paper
  • Article
  • Open Access
1 Citations
2,006 Views
18 Pages

Semi-Correlations for Building Up a Simulation of Eye Irritation

  • Andrey A. Toropov,
  • Alla P. Toropova,
  • Alessandra Roncaglioni and
  • Emilio Benfenati

6 December 2023

The OECD recognizes that data on a compound’s ability to treat eye irritation are essential for the assessment of new compounds on the market. In silico models are frequently used to provide information when experimental data are lacking. Semi-...

(This article belongs to the Section Novel Methods in Toxicology Research)
  • Article
  • Open Access
4 Citations
2,300 Views
17 Pages

Proteomic Analysis of the Mitochondrial Responses in P19 Embryonic Stem Cells Exposed to Florfenicol

  • Zhihua Dong,
  • Xueke Hou,
  • Xueying Wang,
  • Zihui Shen,
  • Huiqing Pang,
  • Lingli Chen,
  • Zhihong Yin,
  • Fei Ren,
  • Weiguo Li and
  • Dongfang Hu
  • + 2 authors

6 December 2023

Florfenicol (FLO) has been shown to elicit diverse toxic effects in plants, insects, and mammals. Previously, our investigations revealed that FLO induced abnormal cardiac development and early embryonic mortality in chicken embryos. However, the eff...

(This article belongs to the Section Drugs Toxicity)
  • Article
  • Open Access
13 Citations
4,620 Views
23 Pages

5 December 2023

Isoeugenol has recently been evaluated as possibly carcinogenic (Group 2B) by the WHO International Agency for Research on Cancer (IARC). In light of this evaluation, an updated risk assessment of this common food constituent was conducted using the...

(This article belongs to the Section Agrochemicals and Food Toxicology)
  • Article
  • Open Access
3 Citations
3,351 Views
22 Pages

5 December 2023

Gaseous polycyclic aromatic hydrocarbons were measured in northern Thailand. No previous studies have provided data on gaseous PAHs until now, so this study determined the gaseous PAHs during two sampling periods for comparison, and then they were us...

(This article belongs to the Topic Advances in Environmental Behaviors of Persistent Contaminants: Fate, Distribution, Risk, and Challenges)
  • Article
  • Open Access
6 Citations
4,203 Views
16 Pages

Titanium Dioxide (TiO2) Nanoparticle Toxicity in a Caenorhabditis elegans Model

  • Sen-Ting Huang,
  • Jian-He Lu,
  • Sherwin M. Jualo,
  • Lemmuel L. Tayo,
  • Wan-Nurdiyana-Wan Mansor,
  • Yi-Chieh Lai,
  • Chih-Lung Wang and
  • How-Ran Chao

5 December 2023

Titanium dioxide is a compound that is used in the food, cosmetic, and paint industries; however, it is still toxic to humans and the environment. This study determined the toxicities of titanium dioxide nanoparticles (TiO2 NPs) in a Caenorhabditis e...

(This article belongs to the Special Issue The 10th Anniversary of Toxics)
  • Article
  • Open Access
8 Citations
3,908 Views
16 Pages

5 December 2023

This study presents the efficiency of a drinking water treatment plant from Constanța, Romania. Individual and aggregated indices are proposed and built using nine water parameters for this aim. The analysis of individual indices permits the det...

(This article belongs to the Special Issue Advances in Water, Air and Soil Pollution Monitoring, Modeling and Restoration)
  • Article
  • Open Access
24 Citations
4,775 Views
14 Pages

Assessment of Biofilm Growth on Microplastics in Freshwaters Using a Passive Flow-Through System

  • Chengyang Jiang,
  • Husein Almuhtaram,
  • Michael J. McKie and
  • Robert C. Andrews

5 December 2023

Biofilms that colonize on the surface of microplastics (MPs) in freshwaters may pose a potential health risk. This study examined factors that influence MP-associated biofilm growth, including polymer type, degree of weathering, and source water qual...

(This article belongs to the Section Emerging Contaminants)
  • Article
  • Open Access
28 Citations
6,083 Views
16 Pages

4 December 2023

Bisphenol A (BPA) exposure has been widely linked to endocrine-disrupting effects. Recently, many substitutes for BPA have been developed as safe structural analogs. However, they have still been reported to have similar adverse effects. The current...

(This article belongs to the Topic Environmental Toxicology and Human Health)
  • Article
  • Open Access
3 Citations
2,801 Views
11 Pages

4 December 2023

The aim of this study was to investigate the association between benzene and toluene, and the ratio of triglycerides to high-density lipoprotein cholesterol (TG/HDL-C). This cross-sectional study analyzed 1928 adults using nationally representative d...

(This article belongs to the Section Human Toxicology and Epidemiology)
  • Article
  • Open Access
11 Citations
4,232 Views
18 Pages

Arecoline-Induced Hepatotoxicity in Rats: Screening of Abnormal Metabolic Markers and Potential Mechanisms

  • Jing Sun,
  • Kai Zhang,
  • Yihui Yin,
  • Yunpeng Qi,
  • Siyuan Li,
  • Haonan Sun,
  • Min Luo,
  • Yixuan Sun,
  • Zhiying Yu and
  • Ling Dong
  • + 4 authors

4 December 2023

Arecoline is a pyridine alkaloid derived from areca nut in the Arecaceae family. It has extensive medicinal activity, such as analgesic, anti-inflammatory, and anti-allergic. However, the toxicity of Arecoline limits its application. Most current stu...

(This article belongs to the Section Agrochemicals and Food Toxicology)
  • Review
  • Open Access
143 Citations
19,875 Views
26 Pages

4 December 2023

The environmental pollution that occurs in direct response to the widespread use of man-made/conventional pesticides results from many chemicals that require a long period of time, often decades, to degrade. The synthetic nature of pesticides also ha...

(This article belongs to the Special Issue Pesticide Risk Assessment, Emerging and Re-Emerging Problems)
  • Review
  • Open Access
8 Citations
3,229 Views
26 Pages

Recent Advances in Black Phosphorous-Based Photocatalysts for Degradation of Emerging Contaminants

  • Zhaocheng Zhang,
  • Dongyang He,
  • Kangning Zhang,
  • Hao Yang,
  • Siyu Zhao and
  • Jiao Qu

3 December 2023

The recalcitrant nature of emerging contaminants (ECs) in aquatic environments necessitates the development of effective strategies for their remediation, given the considerable impacts they pose on both human health and the delicate balance of the e...

(This article belongs to the Special Issue Advances in Photocatalytic Degradation of Emerging Contaminants)
  • Article
  • Open Access
10 Citations
2,984 Views
17 Pages

MicroRNA miR-212-5p Regulates the MEK/ERK Signaling Pathway by Targeting A-Raf proto-oncogene serine/threonine-protein kinase (ARAF) to Regulate Cowshed PM2.5-Induced NR8383 Apoptosis

  • Ke Sun,
  • Yize Sun,
  • Yunna Jia,
  • Xinran Duan,
  • Zhenhua Ma,
  • Xiqing Zhang,
  • Lixia Wang,
  • Yanbin Zhu,
  • Yunhang Gao and
  • Wangdui Basang

3 December 2023

Objective: To investigate the role of miR-212-5p-targeted ARAF during the apoptosis of rat alveolar macrophages induced by cowshed PM2.5. Methods: miRNA and related target genes and pathways were predicted using the KEGG, TargetScan, and other predic...

(This article belongs to the Section Hormesis in Toxicology)
  • Article
  • Open Access
10 Citations
3,331 Views
15 Pages

3 December 2023

Mycotoxins are produced by more than one hundred fungi and produce secondary metabolites that contaminate various agricultural commodities, especially rice and corn. Their presence in the food chain is considered a serious problem worldwide. In recen...

(This article belongs to the Section Reproductive and Developmental Toxicity)
  • Article
  • Open Access
32 Citations
5,591 Views
24 Pages

Association of Combined Metals and PFAS with Cardiovascular Disease Risk

  • Yvonne S. Boafo,
  • Sayed Mostafa and
  • Emmanuel Obeng-Gyasi

1 December 2023

This study sought to investigate the impact of exposure to metals and per- and polyfluoroalkyl substances (PFASs) on cardiovascular disease (CVD)-related risk. PFASs, including PFOA, PFOS, PFNA, and PFHxS, as well as metals such as lead (Pb), cadmium...

(This article belongs to the Section Metals and Radioactive Substances)

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Toxics - ISSN 2305-6304