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2013	Inaugural issue released, initially published as a quarterly journal.
2016	Indexed in the Emerging Sources Citation Index (ESCI - Web of Science). Toxics starts the Travel Awards project.
2017	Covered in Scopus from Vol. 5 (2017). Full-text archived in PubMed Central, with abstracts available through PubMed, from Vol. 3.
2018	The journal is divided into four topical sections: Toxicology and Public Health, Risk Assessment and Risk Management, Environmental Chemistry and Ecotoxicology.
2019	Toxics has its first CiteScore 2.84. Toxics has been accepted for coverage in the Science Citation Indexed Expanded (SCIE) in Web of Science.
2020	Received its first impact factor of 3.271. CiteScore increased to 3.7.
2021	2020 Impact factor increased to 4.146. CiteScore 2020 increased to 4.6.

2013–2018	Founding Editor-in-Chief: Prof. Dr. David Bellinger
2018–2020	Editor-in-Chief: Prof. Dr. Alistair Boxall Section Editor-in-Chief: Prof. Dr. Kyungho Choi for Section “Toxicology and Public Health” Section Editor-in-Chief: Prof. Dr. Paul Van den Brink for Section “Ecotoxicology” Section Editor-in-Chief: Prof. Dr. Alistair Boxall for Section “Risk Assessment and Risk Management” Section Editor-in-Chief: Dr. Sally Gaw for Section “Environmental Chemistry”
2020–	Section Editor-in-Chief: Prof. Dr. Soterios A. Kyrtopoulos for Section “Exposome” Section Editor-in-Chief: Dr. Gunnar Toft for Section “Environmental Epidemiology” Section Editor-in-Chief: Prof. Dr. Pierre Herckes for Section “Environmental Chemistry”
2021–	Editor-in-Chief: Dr. Demetrio Raldúa Section Editor-in-Chief: Dr. Martí Nadal for Section “Risk Assessment and Management” Section Editor-in-Chief: Dr. Demetrio Raldúa for Section “Ecotoxicology”