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Viruses, Volume 11, Issue 1

January 2019 - 90 articles

Cover Story: KDEL receptors, a family of seven-transmembrane proteins, retrieve chaperones such as GRP78 containing the C-terminal tetra peptide sequence KDEL (Lys-Asp-Glu-Leu) in the ER, and thus regulate the maturation and fate of other proteins. KDEL receptor over-expression disturbs this sensitive equilibrium between chaperones available for newly synthesized proteins and retrieved chaperones, and impairs measles virus replication by reducing the transport of viral envelope proteins to the cell surface. View Paper here.
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Articles (90)

  • Article
  • Open Access
28 Citations
5,760 Views
14 Pages

Isolation of a T7-Like Lytic Pasteurella Bacteriophage vB_PmuP_PHB01 and Its Potential Use in Therapy against Pasteurella multocida Infections

  • Yibao Chen,
  • Guanghao Guo,
  • Erchao Sun,
  • Jiaoyang Song,
  • Lan Yang,
  • Lili Zhu,
  • Wan Liang,
  • Lin Hua,
  • Zhong Peng and
  • Xibiao Tang
  • + 2 authors

21 January 2019

A lytic bacteriophage PHB01 specific for Pasteurella multocida type D was isolated from the sewage water collected from a pig farm. This phage had the typical morphology of the family Podoviridae, order Caudovirales, presenting an isometric polyhedra...

  • Article
  • Open Access
18 Citations
6,916 Views
12 Pages

Aerosol and Contact Transmission Following Intranasal Infection of Mice with Japanese Encephalitis Virus

  • Chunxia Chai,
  • Rachel Palinski,
  • Yixuan Xu,
  • Qiao Wang,
  • Sanjie Cao,
  • Yi Geng,
  • Qin Zhao,
  • Yiping Wen,
  • Xiaobo Huang and
  • Qiguai Yan
  • + 6 authors

21 January 2019

The Japanese encephalitis virus (JEV), a causative agent of severe viral encephalitis in humans, has a biological cycle fluctuating between transmission in mosquitoes and avian species and amplification in pigs. Contact transmission of JEV was recent...

  • Article
  • Open Access
125 Citations
13,360 Views
16 Pages

Design and Preclinical Development of a Phage Product for the Treatment of Antibiotic-Resistant Staphylococcus aureus Infections

  • Susan M. Lehman,
  • Gillian Mearns,
  • Deborah Rankin,
  • Robert A. Cole,
  • Frenk Smrekar,
  • Steven D. Branston and
  • Sandra Morales

21 January 2019

Bacteriophages, viruses that only kill specific bacteria, are receiving substantial attention as nontraditional antibacterial agents that may help alleviate the growing antibiotic resistance problem in medicine. We describe the design and preclinical...

  • Communication
  • Open Access
22 Citations
5,290 Views
11 Pages

21 January 2019

Monilinia fructicola and Monilinia laxa are the most destructive fungal species infecting stone fruit (Prunus species). High-throughput cDNA sequencing of M. laxa and M. fructicola isolates collected from stone fruit orchards revealed that 14% of iso...

  • Article
  • Open Access
29 Citations
6,538 Views
11 Pages

Double-Stranded RNA High-Throughput Sequencing Reveals a New Cytorhabdovirus in a Bean Golden Mosaic Virus-Resistant Common Bean Transgenic Line

  • Dione M. T. Alves-Freitas,
  • Bruna Pinheiro-Lima,
  • Josias C. Faria,
  • Cristiano Lacorte,
  • Simone G. Ribeiro and
  • Fernando L. Melo

21 January 2019

Using double-strand RNA (dsRNA) high-throughput sequencing, we identified five RNA viruses in a bean golden mosaic virus (BGMV)-resistant common bean transgenic line with symptoms of viral infection. Four of the identified viruses had already been de...

  • Review
  • Open Access
43 Citations
5,858 Views
16 Pages

20 January 2019

Although Hepatitis E is increasingly described as a major cause of liver disease in industrialized countries, the epidemiology is far from being fully elucidated. We provide here a comprehensive review of documented clusters of cases, and of serologi...

  • Review
  • Open Access
55 Citations
11,087 Views
25 Pages

20 January 2019

The incorporation of biologically active host proteins into HIV-1 is a well-established phenomenon, particularly due to the budding mechanism of viral egress in which viruses acquire their external lipid membrane directly from the host cell. While th...

  • Article
  • Open Access
28 Citations
5,611 Views
15 Pages

A Victorivirus and Two Novel Mitoviruses Co-Infected the Plant Pathogen Nigrospora oryzae

  • Hong Liu,
  • Rui Liu,
  • Chang Xin Li,
  • Hui Wang,
  • Hong Jian Zhu,
  • Bi Da Gao,
  • Qian Zhou and
  • Jie Zhong

19 January 2019

Three dsRNAs, in sizes of approximately 2.5–5 kbp, were detected in the plant pathogenic fungus Nigrospora oryzae strain CS-7.5-4. Genomic analysis showed that the 5.0 kb dsRNA was a victorivirus named as Nigrospora oryzae victorivirus 2 (NoRV2...

  • Review
  • Open Access
41 Citations
9,222 Views
17 Pages

Half a Century of Research on Membrane-Containing Bacteriophages: Bringing New Concepts to Modern Virology

  • Sari Mäntynen,
  • Lotta-Riina Sundberg,
  • Hanna M. Oksanen and
  • Minna M. Poranen

18 January 2019

Half a century of research on membrane-containing phages has had a major impact on virology, providing new insights into virus diversity, evolution and ecological importance. The recent revolutionary technical advances in imaging, sequencing and lipi...

  • Communication
  • Open Access
45 Citations
5,931 Views
13 Pages

Comparison of Anti-Viral Activity of Frog Skin Anti-Microbial Peptides Temporin-Sha and [K3]SHa to LL-37 and Temporin-Tb against Herpes Simplex Virus Type 1

  • Maëva Roy,
  • Lucie Lebeau,
  • Céline Chessa,
  • Alexia Damour,
  • Ali Ladram,
  • Bruno Oury,
  • David Boutolleau,
  • Charles Bodet and
  • Nicolas Lévêque

18 January 2019

Temporins are anti-microbial peptides synthesized in the skin of frogs of the Ranidae family. The few studies to date that have examined their anti-viral properties have shown that they have potential as anti-viral therapies. In this work, we evaluat...

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Viruses - ISSN 1999-4915