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Viruses 2019, 11(1), 74; https://doi.org/10.3390/v11010074

Middle East Respiratory Syndrome Vaccine Candidates: Cautious Optimism

Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, 77555 TX, USA
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Received: 18 December 2018 / Revised: 10 January 2019 / Accepted: 12 January 2019 / Published: 17 January 2019
(This article belongs to the Special Issue MERS-CoV)
Full-Text   |   PDF [646 KB, uploaded 17 January 2019]   |  

Abstract

Efforts towards developing a vaccine for Middle East respiratory syndrome coronavirus (MERS-CoV) have yielded promising results. Utilizing a variety of platforms, several vaccine approaches have shown efficacy in animal models and begun to enter clinical trials. In this review, we summarize the current progress towards a MERS-CoV vaccine and highlight potential roadblocks identified from previous attempts to generate coronavirus vaccines. View Full-Text
Keywords: Middle East respiratory syndrome coronavirus; severe acute respiratory syndrome coronavirus; coronavirus spike glycoprotein; vaccine platforms; correlates of immunity; animal models Middle East respiratory syndrome coronavirus; severe acute respiratory syndrome coronavirus; coronavirus spike glycoprotein; vaccine platforms; correlates of immunity; animal models
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Schindewolf, C.; Menachery, V.D. Middle East Respiratory Syndrome Vaccine Candidates: Cautious Optimism. Viruses 2019, 11, 74.

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