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  • Article
  • Open Access
4 Citations
6,082 Views
13 Pages

Dog trials and competitions involve various sport disciplines, e.g., obedience, agility, working dog trials and rally obedience. Dog handlers navigate their dogs through physically and mentally demanding tasks. The purpose of this study was to gain a...

  • Review
  • Open Access
3 Citations
6,490 Views
13 Pages

Working dogs are an essential part of modern society, and police canines (K9s) in the United States are amongst the most recognizable of all working dogs. Given the dearth of published data on active police canines in the U.S. and the calls for polic...

  • Article
  • Open Access
12 Citations
5,478 Views
16 Pages

26 September 2021

Working trials is a competitive canine discipline based on work undertaken by military and police dogs. A 9 ft long jump is a key component of the discipline. Research into landing forces and joint angulation in other canine disciplines has highlight...

(This article belongs to the Section Companion Animals)
  • Article
  • Open Access
310 Views
14 Pages

11 October 2026

Degenerative joint disease, including osteoarthritis (OA), is frequently diagnosed in working dogs and is a major cause of retirement or euthanasia. Pregabalin is a gabapentinoid used mainly for neuropathic pain, but evidence for pregabalin monothera...

(This article belongs to the Section Veterinary Clinical Studies)
  • Review
  • Open Access
4 Citations
7,509 Views
33 Pages

The Role of Olfaction in Dogs: Evolution, Biology, and Human-Oriented Work

  • Iwona Kowalczyk-Jabłońska,
  • Paulina Jundziłł-Bogusiewicz and
  • Tadeusz Kaleta

29 January 2026

Dogs show exceptional olfactory sensitivity and are widely used in medical, rescue, military, and forensic applications, yet the determinants of individual and breed-level scent-work performance remain incompletely characterized. This review integrat...

(This article belongs to the Section Human-Animal Interactions, Animal Behaviour and Emotion)
  • Article
  • Open Access
15 Citations
14,328 Views
14 Pages

A Randomized Cross-Over Study Comparing Cooling Methods for Exercise-Induced Hyperthermia in Working Dogs in Training

  • Sara C. Parnes,
  • Amritha Mallikarjun,
  • Meghan T. Ramos,
  • Tesa A. Stone and
  • Cynthia M. Otto

28 November 2023

Working dogs are at a high risk of canine non-pyrogenic hyperthermia, a life-threatening condition that can occur due to physical exertion or environmental factors that inhibit dogs’ ability to cool themselves. Two frequently recommended coolin...

(This article belongs to the Special Issue Sports Medicine and Rehabilitation in Companion Animals)
  • Article
  • Open Access
7 Citations
5,176 Views
9 Pages

Removal of Aerosolized Contaminants from Working Canines via a Field Wipe-Down Procedure

  • Erin B. Perry,
  • Dakota R. Discepolo,
  • Stephen Y. Liang and
  • Eileen K. Jenkins

8 January 2021

Evidence-based canine decontamination protocols are underrepresented in the veterinary literature. Aerosolized microbiological and chemical contaminants can pose a risk in deployment environments highlighting the need for improved canine field decont...

(This article belongs to the Collection Health, Behaviour and Performance in Working Dog Teams)
  • Feature Paper
  • Article
  • Open Access
6 Citations
7,589 Views
14 Pages

Scent Detection Threshold of Trained Dogs to Eucalyptus Hydrolat

  • Soile Turunen,
  • Susanna Paavilainen,
  • Jouko Vepsäläinen and
  • Anna Hielm-Björkman

3 April 2024

Dogs’ (Canis lupus familiaris) sense of smell is based on a unique anatomy and physiology that enables them to find and differentiate low concentrations of odor molecules. This ability is exploited when dogs are trained as search, rescue, or me...

(This article belongs to the Section Human-Animal Interactions, Animal Behaviour and Emotion)
  • Case Report
  • Open Access
6 Citations
4,688 Views
8 Pages

An African Canine Trypanosomosis Case Import: Is There a Possibility of Creating a Secondary Focus of Trypanosoma congolense Infection in France?

  • Florence Calvet,
  • Hacène Medkour,
  • Oleg Mediannikov,
  • Caroline Girardet and ,
  • Antoine Jacob,
  • Mickaël Boni and
  • Bernard Davoust
  • + 2 authors+ 0 author

27 August 2020

African animal trypanosomosis are parasitic diseases caused by several protozoa of the genus Trypanosoma, transmitted by hematophagous insects, essentially tsetse flies, but also, less frequently by Tabanidae and Stomoxidae. They are geolocated in a...

(This article belongs to the Special Issue Animal Parasitic Diseases)
  • Article
  • Open Access
1 Citations
2,947 Views
9 Pages

Observational Study on Cardiac Activity in Rescue Dogs with Holter and Electrocardiogram Methodologies during a Simulated Search Activity

  • Mirella Lopedote,
  • Annarita Amodio,
  • Maria Ferrara,
  • Francesca Sciutto and ,
  • Maria Stella Rigo and
  • Giuseppe Spinella
  • + 1 author+ 0 author

18 June 2024

The aim of this study was to observe electric cardiac activity in real working conditions, with the application of Holter and the electrocardiogram in search and rescue dogs. Thirty-one handlers of search and rescue dogs voluntarily participated in t...

(This article belongs to the Section Companion Animals)
  • Feature Paper
  • Article
  • Open Access
Animals2026, 16(21), 3457;https://doi.org/10.3390/ani16213457 
(registering DOI)

2 November 2026

Decisions regarding neutering in athletic sled dogs involve a complex balance between health, behaviour, performance, breeding objectives, and management considerations. However, evidence regarding neutering practices and their relationship with heal...

(This article belongs to the Special Issue Sports Medicine and Rehabilitation in Companion Animals: Second Edition)
  • Feature Paper
  • Article
  • Open Access
1 Citations
779 Views
18 Pages

Accelerometry-Based Assessment of Overnight Coat Use on Dog Sleep and Activity Patterns: Implications for Farm Dog Welfare

  • Ting Wang,
  • Michelle Smit,
  • Xuan Cai,
  • Rene A. Corner-Thomas and ,
  • Ina Draganova,
  • Christopher J. Andrews and
  • David G. Thomas
  • + 2 authors+ 0 author

2 July 2026

New Zealand working farm dogs can struggle to maintain their body weight and condition during periods of high workload, despite substantial energy intake, highlighting the need to optimise energy balance. One potential strategy for reducing overall e...

(This article belongs to the Section Companion Animals)
  • Case Report
  • Open Access
543 Views
8 Pages

16 June 2026

Rocky Mountain spotted fever (RMSF), caused by Rickettsia rickettsii, is a potentially severe tick-borne disease affecting both dogs and humans. While commercial in-clinic diagnostic tests have improved the detection of several common canine tick-bor...

  • Article
  • Open Access
12 Citations
6,723 Views
16 Pages

8 September 2022

Nose work with military working dogs (MWDs) in warmer-than-usual areas has led us to look for new tools to reduce both heat stress and the risk of heat stroke. One of the different strategies to manage heat stress is the use of cooling vests, such as...

(This article belongs to the Special Issue Physical Training of Working, Service and Sporting Dogs)
  • Review
  • Open Access
6 Citations
4,522 Views
13 Pages

The Effect of Dog Presence on the Therapeutic Alliance: A Systematic Review

  • Timothy Collier,
  • Pauleen Bennett,
  • Vanessa Rohlf and
  • Tiffani Howell

1 December 2022

The development of a therapeutic alliance represents one of the most important processes that occurs in psychological therapy and is one of the strongest predictors of treatment outcome. To ensure the effective delivery of psychological interventions...

(This article belongs to the Section Veterinary Education, Veterinary Communication and Animal Behavior)
  • Case Report
  • Open Access
1 Citations
7,391 Views
16 Pages

Bone Lesions in a Young Dog and a NEEM (Azadirachta indica) Spray as the Only Preventive Measure against Leishmaniasis: A Case Report

  • Giulia De Feo,
  • George Lubas,
  • Simonetta Citi,
  • Caterina Puccinelli and
  • Roberto Amerigo Papini

As the spread of canine leishmaniasis (CanL) is increasing throughout the world, the need for effective agents to prevent its transmission has intensified. In this case report, an intact 1.5-year-old male French bulldog was presented for treatment of...

(This article belongs to the Special Issue Feature Papers of Zoonotic Diseases 2021–2022)
  • Case Report
  • Open Access
4 Citations
8,530 Views
14 Pages

We report a rare and interesting case of mixed infection with Leishmania infantum and Dirofilaria immitis associated with the incidental finding of microfilariae in the bone marrow of a 9-year-old, intact, male Bullmastiff which was seropositive to L...

  • Article
  • Open Access
6 Citations
6,309 Views
21 Pages

Study on the Viability of Canine Nose Pattern as a Unique Biometric Marker

  • Hyeong In Choi,
  • Mu-Young Kim,
  • Hun-Young Yoon,
  • Sungjin Lee and ,
  • Stephanie Sujin Choi,
  • Chang Yong Han,
  • Hwan Pyo Moon,
  • Changhyun Byun and
  • Song-Hwa Kwon
  • + 4 authors+ 0 author

25 November 2021

The uniqueness of the canine nose pattern was studied. A total of 180 nose images of 60 dogs of diverse age, gender, and breed were collected. The canine nose patterns in these images were examined visually and by a biometric algorithm. It was found...

(This article belongs to the Section Companion Animals)
  • Article
  • Open Access
19 Citations
11,229 Views
11 Pages

A Randomized Cross-Over Trial Comparing the Effect of Intramuscular Versus Intranasal Naloxone Reversal of Intravenous Fentanyl on Odor Detection in Working Dogs

  • Jennifer L. Essler,
  • Paige G. Smith,
  • Danielle Berger,
  • Elizabeth Gregorio and ,
  • M. Ross Pennington,
  • Amanda McGuire,
  • Kenneth G. Furton and
  • Cynthia M. Otto
  • + 3 authors+ 0 author

22 June 2019

Fentanyl is a potent opioid used clinically as a pain medication and anesthetic but has recently seen a sharp rise as an illicit street drug. The potency of fentanyl means mucous membrane exposure to a small amount of the drug can expose first respon...

(This article belongs to the Special Issue Cognition and Olfaction of Dogs)
  • Article
  • Open Access
4 Citations
4,118 Views
14 Pages

Advances in Canine Anesthesia: Physiologically Based Pharmacokinetic Modeling for Predicting Propofol Plasma Profiles in Canines with Hepatic Impairment

  • Lucas Wamser Fonseca Gonzaga,
  • Beatriz Monte Egito,
  • João Bosco Costa Coelho,
  • Gabriela Pereira Souza and ,
  • Frederico Severino Martins and
  • Marcos Ferrante
  • + 1 author+ 0 author

19 December 2024

Background: A PBPK model allows the prediction of the concentration of drug amounts in different tissues and organs over time and can be used to simulate and optimize different therapeutic protocols in healthy and sick individuals. The objective of t...

(This article belongs to the Section Pharmacology)
  • Article
  • Open Access
15 Citations
3,321 Views
14 Pages

Predictive Analysis of Maxillary Canine Impaction through Sella Turcica Bridging, Ponticulus Posticus Calcification, and Lateral Incisor Anomalies: A Retrospective Observational Study

  • Rosanna Guarnieri,
  • Francesca Germanò,
  • Federica Altieri,
  • Michele Cassetta and ,
  • Camilla Grenga,
  • Gabriella Padalino,
  • Roberto Di Giorgio and
  • Ersilia Barbato
  • + 3 authors+ 0 author

21 November 2022

Maxillary canine impaction is an increasing dental anomaly and is often related to other dento-skeletal anomalies. The aim of this work is to support the clinician in evaluating the relationship between a displaced maxillary canine and clinical (the...

(This article belongs to the Special Issue Modern Approaches and Innovations on Methods and Imaging Protocols of the Maxillofacial District)
  • Review
  • Open Access
22 Citations
5,285 Views
9 Pages

MiRNAs in Canine and Human Osteosarcoma: A Highlight Review on Comparative Biomolecular Aspects

  • Leonardo Leonardi,
  • Katia Scotlandi,
  • Ilaria Pettinari,
  • Maria Serena Benassi and ,
  • Ilaria Porcellato and
  • Laura Pazzaglia
  • + 1 author+ 0 author

18 February 2021

Osteosarcoma (OS) is the most frequent primary malignant tumor of bone in humans and animals. Comparative oncology is a field of study that examines the cancer risk and tumor progression across the species. The canine model is ideally suited for tran...

(This article belongs to the Special Issue Research Advances and Therapy of Human Osteosarcoma)
  • Article
  • Open Access
4 Citations
3,482 Views
12 Pages

Two-Dimensional Radiographic Diagnosis of Maxillary Canine Impactions

  • Alin M. Iacob,
  • Matías Ferrán Escobedo Martínez,
  • Sonsoles Olay García,
  • Sonsoles Junquera Olay and
  • Luis Manuel Junquera Gutiérrez

13 November 2024

Background: The primary aim of this study was to evaluate, using conventional radiographic imaging, the height, angulation, and mesiodistal position of impacted maxillary canines to determine if these variables are significantly associated with the p...

(This article belongs to the Special Issue Tradition and Innovation in Orthodontics)
  • Brief Report
  • Open Access
1 Citations
4,531 Views
12 Pages

Working like a Dog: Exploring the Role of a Therapy Dog in Clinical Exercise Physiology Practice

  • Melainie Cameron,
  • Emily Hewitt,
  • Elizabeth Hollitt,
  • Jacqueline Wood and
  • Samantha Brown

11 May 2022

Therapy animals in clinical settings are purported to reduce patients’ anxiety, decrease agitated behaviour, serve as social mediators, enhance the social atmosphere, and increase patients’ openness towards practitioners. A therapy dog wo...

(This article belongs to the Special Issue Human-Animal Communication)
  • Article
  • Open Access
12 Citations
8,239 Views
12 Pages

Body Temperature Responses During Phases of Work in Human Remains Detection Dogs Undergoing a Simulated Deployment

  • Janice Baker,
  • Mallory DeChant,
  • Eileen Jenkins,
  • George Moore and ,
  • Kathleen Kelsey and
  • Erin Perry
  • + 1 author+ 0 author

13 April 2020

Body temperature responses were recorded during phases of work (waiting-to-work in close proximity to search site, active work in a search site, and post-work recovery crated in vehicle) in human remains detection dogs during search training. State o...

(This article belongs to the Special Issue Animal Transport on the Road: In Practice)
  • Article
  • Open Access
7 Citations
9,920 Views
10 Pages

Pseudo-Placentational Endometrial Hyperplasia in the Bitch: Case Series

  • Gabriele Marino,
  • Alessandra Sfacteria,
  • Giuseppe Catone,
  • Antonina Zanghì and ,
  • Fabiana Pecchia,
  • Angela Difrancesco and
  • Marco Russo
  • + 2 authors+ 0 author

6 March 2021

Canine pseudo-placentational endometrial hyperplasia differs from the classical form of cystic endometrial hyperplasia for the well-organized tissue architecture resembling the canine placenta. After the discovery, it has been inconstantly reported....

(This article belongs to the Special Issue Veterinary and Comparative Reproductive Pathology)
  • Article
  • Open Access
6 Citations
5,662 Views
12 Pages

Characterization of Primary Cultures of Normal and Neoplastic Canine Melanocytes

  • Monica Sforna,
  • Elisabetta Chiaradia,
  • Ilaria Porcellato,
  • Serenella Silvestri and ,
  • Giulia Moretti,
  • Luca Mechelli and
  • Chiara Brachelente
  • + 2 authors+ 0 author

10 March 2021

Although numerous animal models, especially mouse models, have been established for the study of melanoma, they often fail to accurately describe the mechanisms of human disease because of their anatomic, physiological, and immune differences. The do...

(This article belongs to the Special Issue Spontaneous Neoplasms in Animals)
  • Article
  • Open Access
4 Citations
3,296 Views
12 Pages

In Silico and In Vitro Evaluation of Bevacizumab Biosimilar MB02 as an Antitumor Agent in Canine Mammary Carcinoma

  • Georgina A. Cardama,
  • Paula L. Bucci,
  • Jesús S. Lemos,
  • Candela Llavona and ,
  • Micaela A. Benavente,
  • Eva Hellmén,
  • María Laura Fara,
  • Eduardo Medrano,
  • Eduardo Spitzer and
  • Daniel F. Alonso
  • + 8 authors+ 3 authors

3 August 2023

Canine mammary carcinomas (CMC) are associated with major aggressive clinical behavior and high mortality. The current standard of care is based on surgical resection, without an established effective treatment scheme, highlighting the urgent need to...

(This article belongs to the Special Issue Recent Advances in Canine Mammary Tumors)
  • Article
  • Open Access
1,580 Views
12 Pages

Predicting Lyme Disease: A One Health Approach

  • Mollie McDermott,
  • Shamim Sarkar,
  • Janice O’Brien,
  • Karen Gruszynski and ,
  • Barbara Shock,
  • Vina Faulkner and
  • Lauren Wisnieski
  • + 2 authors+ 0 author

Lyme disease is the most common vector-borne disease in North America. Predicting Lyme disease incidence is a key component of public health preparedness. Previously, we demonstrated that the volume of data searches on Google Trends for terms related...

(This article belongs to the Topic Vector-Borne Disease Spatial Epidemiology, Disease Ecology, and Zoonoses)
  • Article
  • Open Access
1 Citations
1,117 Views
16 Pages

Investigation of the Impact of Extraneous Odours on the Detection Capability of Explosive Detection Dogs Under a Controlled Test Environment

  • Christopher Becher,
  • Michaela Schneider,
  • Stephan Maurer,
  • Savanna Sewell and ,
  • Jörg Schulenburg and
  • Peter Kaul
  • + 1 author+ 0 author

19 February 2026

In this work, an experimental procedure that enables testing of canine detection capabilities is described. The developed testbed includes an experimental setup with six exchangeable detection/sniffing boxes for odour masking experiments as well as a...

(This article belongs to the Section Human-Animal Interactions, Animal Behaviour and Emotion)
  • Article
  • Open Access
5 Citations
5,055 Views
8 Pages

When Veterinarians Support Canine Therapy: Bidirectional Benefits for Clinics and Therapy Programs

  • John-Tyler Binfet,
  • Haley J. Silas,
  • Sean W. Longfellow and
  • Katrina Widmaier-Waurechen

4 January 2018

This paper proposes a mutually beneficial model of collaboration between veterinarians and canine therapy programs. Veterinarians and the clinics for whom they work routinely establish collaborations with multiple and varied stakeholders. This might...

  • Article
  • Open Access
1,885 Views
16 Pages

Gene Expression and Immunohistochemical Analyses of c-Myc in Canine and Feline Soft Tissue Fibrosarcomas

  • Waseem Al-Jameel,
  • Ahmad Al-Saidya,
  • Baidaa Salah,
  • Hana Ismail and
  • Saevan Al-Mahmood

12 February 2026

Canine and feline fibrosarcomas are malignant tumors of mesenchymal origin showing histological, molecular, and clinical structures similar to their human equivalent. In human medicine, cellular myelocytomatosis (c-Myc) has already been proposed as a...

(This article belongs to the Section Companion Animals)
  • Article
  • Open Access
5 Citations
5,534 Views
22 Pages

Study on the Correlation Between Aggressive Behavior and Gut Microbiota and Serum Serotonin (5-HT) in Working Dogs

  • Ning Sun,
  • Liuwei Xie,
  • Jingjing Chao,
  • Fuxiao Xiu and ,
  • He Zhai,
  • Yuanting Zhou,
  • Xi Yu and
  • Yingyi Shui
  • + 3 authors+ 0 author

Aggressive canine behavior poses a significant threat to public health. Understanding aggressive behavior is crucial for canine socialization and human–dog interactions. This study conducted an exploratory analysis of working dogs to investigat...

(This article belongs to the Special Issue Gastrointestinal Disease and Health in Pets)
  • Review
  • Open Access
28 Citations
15,592 Views
25 Pages

Autochthonous Human and Canine Strongyloides stercoralis Infection in Europe: Report of a Human Case in An Italian Teen and Systematic Review of the Literature

  • Letizia Ottino,
  • Dora Buonfrate,
  • Paola Paradies,
  • Zeno Bisoffi and ,
  • Alberto Antonelli,
  • Gian Maria Rossolini,
  • Simona Gabrielli,
  • Alessandro Bartoloni and
  • Lorenzo Zammarchi
  • + 4 authors+ 0 author

Autochthonous human and canine strongyloidiasis is reported in Europe but is unclear whether the transmission of infection still occurs. We report a previously unpublished human case in an Italian teen and perform a systematic review of literature on...

(This article belongs to the Special Issue Prevalence of Strongyloidiasis and Schistosomiasis)
  • Article
  • Open Access
1,283 Views
18 Pages

First Molecular Insights into the Presence of Canine Kobuvirus in Ecuadorian Dogs Through the Standardization of a Sensitive SYBR Green RT-qPCR Assay

  • Camila Sanchez-Castro,
  • Anthony Loor-Giler,
  • Silvana Santander-Parra,
  • Martín Campos and ,
  • Renán Mena-Pérez,
  • Santiago Prado-Chiriboga and
  • Luis Nuñez
  • + 2 authors+ 0 author

10 November 2025

Canine Kobuvirus (CaKoV) has been identified as an agent involved in gastrointestinal diseases among dogs worldwide, with a particular impact on young individuals. This study reports the first molecular detection of CaKoV in Ecuadorian dogs with gast...

  • Article
  • Open Access
6 Citations
2,575 Views
14 Pages

Conductance Changes of Na+ Channels during the Late Na+ Current Flowing under Action Potential Voltage Clamp Conditions in Canine, Rabbit, and Guinea Pig Ventricular Myocytes

  • Balázs Horváth,
  • Zsigmond M. Kovács,
  • Csaba Dienes,
  • József Óvári and ,
  • Norbert Szentandrássy,
  • János Magyar,
  • Tamás Bányász,
  • András Varró and
  • Péter P. Nánási
  • + 4 authors+ 0 author

Late sodium current (INa,late) is an important inward current contributing to the plateau phase of the action potential (AP) in the mammalian heart. Although INa,late is considered as a possible target for antiarrhythmic agents, several aspects of th...

(This article belongs to the Special Issue New Advances in Antiarrhythmic Drugs)
  • Article
  • Open Access
7 Citations
5,582 Views
11 Pages

Connexin 26 and Connexin 43 in Canine Mammary Carcinoma

  • Savannah Luu,
  • Cynthia Bell,
  • Sarah Schneider and
  • Thu Annelise Nguyen

9 December 2019

Incidence of canine mammary carcinoma is two times higher than the rate of human breast cancer. Mammary tumors are the most common type of cancer in intact female dogs and account for about half of all neoplasms in these dogs. Well-established models...

  • Feature Paper
  • Article
  • Open Access
2 Citations
2,260 Views
11 Pages

A Preliminary Evaluation of the Prognostic Role of HER-2 and HER-3 Immunohistochemical Expression in Canine Melanomas

  • Francesca Parisi,
  • Luigi Aurisicchio,
  • Arianna Pecorari,
  • Alessandro Poli and
  • Francesca Millanta

7 May 2024

Canine melanoma is a malignant and aggressive neoplasm showing clinical, histological, and molecular features similar to the human counterpart. In human medicine, epidermal growth factor receptors (EGFRs) have already been suggested as prognostic mar...

(This article belongs to the Special Issue Cancer Immunotherapy Research in Veterinary Medicine)
  • Article
  • Open Access
9 Citations
3,949 Views
11 Pages

The true extent of tick-borne disease (TBD) incidence and risk among humans is largely unknown, posing significant public health challenges. This study offers an exploratory analysis of a multimodal dataset and is part of a larger ongoing project to...

(This article belongs to the Special Issue Epidemiology, Surveillance and Prevention of Tick-Borne Diseases)
  • Article
  • Open Access
16 Citations
4,608 Views
16 Pages

Evaluation of Tryptic Podocin Peptide in Urine Sediment Using LC-MS-MRM Method as a Potential Biomarker of Glomerular Injury in Dogs with Clinical Signs of Renal and Cardiac Disorders

  • Barbara Szczepankiewicz,
  • Remigiusz Bąchor,
  • Robert Pasławski,
  • Natalia Siwińska and ,
  • Urszula Pasławska,
  • Andrzej Konieczny and
  • Zbigniew Szewczuk
  • + 2 authors+ 0 author

26 August 2019

The early asymptomatic stage of glomerular injury is a diagnostic challenge in the course of renal and extra-renal disease, e.g., heart insufficiency. It was found that podocin, a podocyte-specific protein present in the urine, may serve as a biomark...

(This article belongs to the Section Analytical Chemistry)
  • Article
  • Open Access
1 Citations
1,669 Views
13 Pages

Comparison Between Strain and 2D Shear Wave Elastography of Testes in Healthy Dogs

  • Francesca Del Signore,
  • Roberta Bucci,
  • Massimo Vignoli,
  • Marco Russo and ,
  • Camilla Smoglica,
  • Andrea De Bonis,
  • Andrea Rubini,
  • Martina Rosto,
  • Augusto Carluccio and
  • Salvatore Parrillo
  • + 6 authors+ 1 author

10 February 2025

Sonoelastography is a rapid and non-invasive ultrasound-based technique to assess tissue elasticity. Interest in this technique’s application in veterinary medicine is progressively increasing, with preliminary reports also available to assess...

(This article belongs to the Special Issue Imaging Techniques and Radiation Therapy in Veterinary Medicine)
  • Article
  • Open Access
7 Citations
2,996 Views
14 Pages

Nisin Influence on the Antimicrobial Resistance Ability of Canine Oral Enterococci

  • Eva Cunha,
  • Rita Janela,
  • Margarida Costa,
  • Luís Tavares and ,
  • Ana Salomé Veiga and
  • Manuela Oliveira
  • + 1 author+ 0 author

10 December 2020

Periodontal disease (PD) is one of the most common diseases in dogs. Although previous studies have shown the potential of the antimicrobial peptide nisin for PD control, there is no information regarding its influence in the development of antimicro...

(This article belongs to the Special Issue Antimicrobial Resistance and Virulence Mechanisms)
  • Article
  • Open Access
4 Citations
3,874 Views
10 Pages

Occurrence of Leishmaniasis in Iberian Wolves in Northwestern Spain

  • Javier Merino Goyenechea,
  • Verónica Castilla Gómez de Agüero,
  • Jesús Palacios Alberti,
  • Rafael Balaña Fouce and
  • María Martínez Valladares

Canine leishmaniasis is an important vector-borne protozoan disease in dogs that is responsible for serious deterioration in their health. In the Iberian Peninsula, as in most countries surrounding the Mediterranean Sea, canine leishmaniasis is cause...

(This article belongs to the Special Issue Vector-Borne Infections in Wildlife)
  • Article
  • Open Access
2 Citations
3,324 Views
8 Pages

Investigating a Prognostic Factor for Canine Hepatocellular Carcinoma: Analysis of Different Histological Grading Systems and the Role of PIVKA-II

  • Lorella Maniscalco,
  • Katia Varello,
  • Emanuela Morello,
  • Vittoria Montemurro and ,
  • Matteo Olimpo,
  • Davide Giacobino,
  • Giuseppina Abbamonte,
  • Cecilia Gola,
  • Selina Iussich and
  • Elena Bozzetta
  • + 5 authors+ 0 author

10 December 2022

Background: Hepatocellular carcinoma (HCC) in dogs is uncommon and often associated with a good prognosis, although some cases prove to be aggressive. In human oncology HCC is often very aggressive and diagnostic methods and prognostic factors are wi...

(This article belongs to the Special Issue Comparative Pathology of Cancers in Animals)
  • Review
  • Open Access
42 Citations
15,278 Views
19 Pages

Pseudomonas spp. in Canine Otitis Externa

  • Bailey Secker,
  • Stephen Shaw and
  • Robert J. Atterbury

Canine otitis externa (OE) is a commonly diagnosed condition seen in veterinary practice worldwide. In this review, we discuss the mechanisms of the disease, with a particular focus on the biological characteristics of Pseudomonas aeruginosa and the...

(This article belongs to the Section Veterinary Microbiology)
  • Article
  • Open Access
2 Citations
4,443 Views
17 Pages

Transcriptome Analysis of Canine Histiocytic Sarcoma Tumors and Cell Lines Reveals Multiple Targets for Therapy

  • Alexander I. Engleberg,
  • Ya-Ting Yang,
  • Peter Z. Schall,
  • Marilia Takada and ,
  • Tuddow Thaiwong-Nebelung,
  • Jacquelyn M. Evans,
  • Elaine A. Ostrander and
  • Vilma Yuzbasiyan-Gurkan
  • + 3 authors+ 0 author

12 March 2025

Background: Histiocytic sarcoma (HS) is a highly aggressive malignancy characterized by the excessive proliferation of histiocytes in dogs and humans. A subset of dog breeds, including the Bernese Mountain Dog (BMD), show a remarkably high prevalence...

(This article belongs to the Section Molecular Cancer Biology)
  • Article
  • Open Access
2 Citations
4,870 Views
14 Pages

First Report on the Molecular Detection of Canine Astrovirus (CaAstV) in Dogs with Gastrointestinal Disease in Ecuador Using a Fast and Sensitive RT-qPCR Assay Based on SYBR Green®

  • Anthony Loor-Giler,
  • Sara Castillo-Reyes,
  • Silvana Santander-Parra,
  • Martín Campos and ,
  • Renán Mena-Pérez,
  • Santiago Prado-Chiriboga and
  • Luis Nuñez
  • + 2 authors+ 0 author

Enteric viruses are responsible for a significant number of gastrointestinal illnesses in dogs globally. One of the main enteric viruses is the canine astrovirus (CaAstV), which causes diarrhea in dogs of various ages. It is linked to symptoms such a...

  • Article
  • Open Access
10 Citations
4,023 Views
27 Pages

Xenobiotic-Free Medium Guarantees Expansion of Adipose Tissue-Derived Canine Mesenchymal Stem Cells Both in 3D Fibrin-Based Matrices and in 2D Plastic Surface Cultures

  • Caterina M. Suelzu,
  • Virna Conti,
  • Youssef Khalidy,
  • Sara Montagna and ,
  • Gabriele Strusi,
  • Rosanna Di Lecce,
  • Priscilla Berni,
  • Giuseppina Basini,
  • Roberto Ramoni and
  • Stefano Grolli
  • + 5 authors+ 0 author

2 December 2020

Mesenchymal stem cells (MSCs) have been recently introduced in veterinary medicine as a potential therapeutic tool for several pathologies. The large-scale in vitro expansion needed to ensure the preparation of a suitable number of MSCs for clinical...

(This article belongs to the Special Issue 3D Stem Cell Culture)
  • Article
  • Open Access
42 Citations
8,866 Views
25 Pages

Portable Rabies Virus Sequencing in Canine Rabies Endemic Countries Using the Oxford Nanopore MinION

  • Crystal M. Gigante,
  • Gowri Yale,
  • Rene Edgar Condori,
  • Niceta Cunha Costa and ,
  • Nguyen Van Long,
  • Phan Quang Minh,
  • Vo Dinh Chuong,
  • Nguyen Dang Tho,
  • Nguyen Tat Thanh and
  • Yu Li
  • + 24 authors+ 19 authors

4 November 2020

As countries with endemic canine rabies progress towards elimination by 2030, it will become necessary to employ techniques to help plan, monitor, and confirm canine rabies elimination. Sequencing can provide critical information to inform control an...

(This article belongs to the Special Issue Lyssaviruses and Other Bat Rhabdoviruses)
  • Article
  • Open Access
6 Citations
5,535 Views
17 Pages

23 February 2024

As interest in animal-assisted therapy (AAT) and canine-assisted psychotherapy (CAP) grows, there are increasing calls for the management of related health, safety, and welfare concerns for canines, providers, and clients. Existing health and safety...

(This article belongs to the Section Human-Animal Interactions, Animal Behaviour and Emotion)

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