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410 Results Found

  • Review
  • Open Access
54 Citations
9,723 Views
12 Pages

Paediatric Palliative Care in Resource-Poor Countries

  • Julia Downing,
  • Sue Boucher,
  • Alex Daniels and
  • Busi Nkosi

19 February 2018

There is a great need for paediatric palliative care (PPC) services globally, but access to services is lacking in many parts of the world, particularly in resource-poor settings. Globally it is estimated that 21.6 million children need access to pal...

  • Review
  • Open Access
29 Citations
6,160 Views
18 Pages

Women in low- and middle-income countries have high rates of perinatal depression. As smartphones become increasingly accessible around the world, there is an opportunity to explore innovative mHealth tools for the prevention, screening, and manageme...

  • Article
  • Open Access
8 Citations
2,772 Views
13 Pages

Promising Perinatal Outcome after Using a Simplified Low-Cost IVF Culture System Specifically Designed for Resource-Poor Countries

  • Willem Ombelet,
  • Jonathan Van Blerkom,
  • Liesbeth Bruckers,
  • Nathalie Dhont,
  • Geeta Nargund and
  • Rudi Campo

15 March 2023

Background: Assisted reproductive techniques services are often not accessible to the majority of infertile couples in Low and Middle Income Countries (LMIC) due to high costs. Lowering IVF laboratory costs is a crucial step to make IVF affordable fo...

  • Article
  • Open Access
20 Citations
10,612 Views
14 Pages

A Descriptive-Multivariate Analysis of Community Knowledge, Confidence, and Trust in COVID-19 Clinical Trials among Healthcare Workers in Uganda

  • Keneth Iceland Kasozi,
  • Anne Laudisoit,
  • Lawrence Obado Osuwat,
  • Gaber El-Saber Batiha,
  • Naif E. Al Omairi,
  • Eric Aigbogun,
  • Herbert Izo Ninsiima,
  • Ibe Michael Usman,
  • Lisa M. DeTora and
  • Susan Christina Welburn
  • + 22 authors

12 March 2021

Background—misinformation and mistrust often undermines community vaccine uptake, yet information in rural communities, especially of developing countries, is scarce. This study aimed to identify major challenges associated with coronavirus disease 2...

  • Article
  • Open Access
38 Citations
7,298 Views
15 Pages

Intersections Between Systems Thinking and Market Shaping for Assistive Technology: The SMART (Systems-Market for Assistive and Related Technologies) Thinking Matrix

  • Malcolm MacLachlan,
  • Joanne McVeigh,
  • Michael Cooke,
  • Delia Ferri,
  • Catherine Holloway,
  • Victoria Austin and
  • Dena Javadi

The Sustainable Development Goals (SDGs) aspire to “leave no-one behind”. Universal access to assistive products is a critical link between the realization of the SDGs and those most likely to be left behind. However, assistive technology...

  • Review
  • Open Access
21 Citations
9,030 Views
14 Pages

Smallholders of poultry production systems in developing countries are commonly found in rural, resource-poor areas, and often face food insecurity. The main constraints for smallholders in poultry production in rural, resource-poor areas are the sho...

  • Article
  • Open Access
3 Citations
3,088 Views
9 Pages

Clinical Performance of Self-Collected Nasal Swabs and Antigen Rapid Tests for SARS-CoV-2 Detection in Resource-Poor Settings

  • Nádia Sitoe,
  • Júlia Sambo,
  • Nédio Mabunda,
  • Neuza Nguenha,
  • Jorfélia Chilaúle,
  • Júlio Rafael,
  • Anésio Macicame,
  • Imelda Chelene,
  • Chishamiso Mudenyanga and
  • Ilesh Jani
  • + 2 authors

19 September 2022

Background: In resource-poor countries, antigen-based rapid tests (Ag-RDTs) performed at primary healthcare and community settings improved access to SARS-CoV-2 diagnostics. However, the technical skills and biosafety requirements inherent to nasopha...

  • Review
  • Open Access
14 Citations
206 Views

Recent Advances in the Diagnosis of Mycobacterium tuberculosis

  • Philip Ifesinachi Anochie,
  • Edwina C Onyeneke,
  • Angelina C Ogu,
  • Anthony C Onyeozirila,
  • Srikanth Aluru,
  • Nneka Onyejepu,
  • Jian Zhang,
  • Lauretta Efere,
  • Mariam A Adetunji and
  • Juan Gabriel Bueno Sánchez

1 September 2012

Molecular technologies offer the greatest potential for laboratories in resource-rich countries because they have the highest sensitivity and specificity. Continued use of new technologies will be crucial in elucidating the true epidemiology and path...

  • Article
  • Open Access
36 Citations
16,004 Views
14 Pages

22 December 2020

This study explores the importance of critical raw materials and minerals by analyzing the Republic of Korea’s recent circular economy and resource security policy. Raw materials and rare metals are becoming increasingly significant to the Kore...

  • Article
  • Open Access
12 Citations
4,496 Views
11 Pages

22 September 2021

Monitoring the development of resistance to the tyrosine kinase inhibitor (TKI) imatinib in chronic myeloid leukemia (CML) patients in the initial chronic phase (CP) is crucial for limiting the progression of unresponsive patients to terminal phase o...

  • Article
  • Open Access
20 Citations
7,932 Views
31 Pages

We All Have a Role to Play: Redressing Inequities for Children Living with CAH and Other Chronic Health Conditions of Childhood in Resource-Poor Settings

  • Kate Armstrong,
  • Alain Benedict Yap,
  • Sioksoan Chan-Cua,
  • Maria E. Craig,
  • Catherine Cole,
  • Vu Chi Dung,
  • Joseph Hansen,
  • Mohsina Ibrahim,
  • Hassana Nadeem and
  • Paul Ward
  • + 2 authors

CLAN (Caring and Living as Neighbours) is an Australian-based non-governmental organisation (NGO) committed to equity for children living with chronic health conditions in resource-poor settings. Since 2004, CLAN has collaborated with a broad range o...

  • Article
  • Open Access
5 Citations
3,793 Views
15 Pages

The IHAT-GUT Iron Supplementation Trial in Rural Gambia: Barriers, Facilitators, and Benefits

  • Isabella Stelle,
  • Lorraine K. McDonagh,
  • Ilias Hossain,
  • Anastasia Z. Kalea and
  • Dora I. A. Pereira

30 March 2021

Introduction: In most sub-Saharan African countries iron deficiency anaemia remains highly prevalent in children and this has not changed in the last 25 years. Supplementation with iron hydroxide adipate tartrate (IHAT) was being investigated in anae...

  • Article
  • Open Access
14 Citations
3,603 Views
21 Pages

7 September 2021

The Belt and Road investment involves a large number of renewable energy projects, but whether the energy efficiency is linked to the Belt and Road Initiative (BRI) cooperation has yet to be established in the literature. This research attempts to cl...

  • Article
  • Open Access
32 Citations
22,941 Views
17 Pages

Assessment of the Health Impacts of Climate Change in Kiribati

  • Lachlan McIver,
  • Alistair Woodward,
  • Seren Davies,
  • Tebikau Tibwe and
  • Steven Iddings

Kiribati—a low-lying, resource-poor Pacific atoll nation—is one of the most vulnerable countries in the World to the impacts of climate change, including the likely detrimental effects on human health. We describe the preparation of a climate change...

  • Proceeding Paper
  • Open Access
4 Citations
24,567 Views
11 Pages

Use of Radioisotopes to Produce High Yielding Crops in Order to Increase Agricultural Production

  • Ayaz Latif Siyal,
  • Akbar Hossain,
  • Fozia Khan Siyal,
  • Tahira Jatt and
  • Sadia Iram

14 February 2022

Nuclear technology can play an important role in innovating weapons capabilities and energy. With the use of the influence of radioisotopes, the agricultural sector has made tremendous progress. Fertilizers are used in agriculture to increase soil fe...

  • Review
  • Open Access
14 Citations
9,643 Views
21 Pages

Improving the Sensitivity and Functionality of Mobile Webcam-Based Fluorescence Detectors for Point-of-Care Diagnostics in Global Health

  • Reuven Rasooly,
  • Hugh Alan Bruck,
  • Joshua Balsam,
  • Ben Prickril,
  • Miguel Ossandon and
  • Avraham Rasooly

Resource-poor countries and regions require effective, low-cost diagnostic devices for accurate identification and diagnosis of health conditions. Optical detection technologies used for many types of biological and clinical analysis can play a signi...

  • Review
  • Open Access
5 Citations
4,114 Views
11 Pages

Acute gastroenteritis (AGE) contributes to increased morbidity and mortality worldwide. In particular, children in resource-poor settings suffer from frequent episodes of diarrhea. A variety of pathogens, including bacteria, viruses, fungi, and proto...

  • Feature Paper
  • Opinion
  • Open Access
36 Citations
7,669 Views
10 Pages

fNIRS for Tracking Brain Development in the Context of Global Health Projects

  • Anna Blasi,
  • Sarah Lloyd-Fox,
  • Laura Katus and
  • Clare E. Elwell

Over the past 25 years, functional near-infrared spectroscopy (fNIRS) has emerged as a valuable tool to study brain function, and it is in younger participants where it has found, arguably, its most successful application. Thanks to its infant-friend...

  • Review
  • Open Access
12 Citations
5,743 Views
16 Pages

Village Chickens for Achieving Sustainable Development Goals 1 and 2 in Resource-Poor Communities: A Literature Review

  • Thando Tenza,
  • Lindokuhle Christopher Mhlongo,
  • Cyprial Ndumiso Ncobela and
  • Zikhona Rani

The rapid increase in the global human population, particularly in Low-Income Food Deficit Countries (LIFDCs), causes severe food shortages. Food shortages are complex and can be linked to economic, environmental, social, and political variables. Har...

  • Article
  • Open Access
6 Citations
6,086 Views
19 Pages

Resource Dynamism of the Rwandan Economy: An Emergy Approach

  • Evariste Rutebuka,
  • Lixiao Zhang,
  • Ernest Frimpong Asamoah,
  • Mingyue Pang and
  • Emmanuel Rukundo

29 May 2018

Africa is experiencing unprecedented economic growth that requires planners to understand the interactions between the social, economic, and ecological systems to ensure its sustainable development. The present paper uses the emergy method to analyse...

  • Review
  • Open Access
5 Citations
228 Views

Arbovirus and Its Potential to Lead the Next Global Pandemic from Sub-Saharan Africa: What Lessons Have We Learned from COVID-19?

  • Elizabeth N. Mbim,
  • Uwem Okon Edet,
  • Henshaw Uchechi Okoroiwu,
  • Francisca O. Nwaokorie,
  • Asanga Effiong Edet,
  • Ayo Owolabi and
  • Mboto Clement I

31 December 2022

Risk and predisposing factors for viral zoonoses abound in the sub-Saharan Africa (SSA) region with significant public health implications. For several decades, there have been several reports on the emergence and re-emergence of arbovirus infections...

  • Review
  • Open Access
21 Citations
5,142 Views
19 Pages

Chimeric Vaccines Based on Novel Insect-Specific Flaviviruses

  • Jessica J. Harrison,
  • Jody Hobson-Peters,
  • Helle Bielefeldt-Ohmann and
  • Roy A. Hall

22 October 2021

Vector-borne flaviviruses are responsible for nearly half a billion human infections worldwide each year, resulting in millions of cases of debilitating and severe diseases and approximately 115,000 deaths. While approved vaccines are available for s...

  • Article
  • Open Access
2 Citations
2,318 Views
18 Pages

Developing countries face a disproportionate degree of threat from climate change. As such, they require and receive significant financial support to address the menace. However, little is known about the potential externalities of this form of exter...

  • Review
  • Open Access
143 Citations
28,244 Views
20 Pages

Transmission of Hepatitis E Virus in Developing Countries

  • Mohammad S. Khuroo,
  • Mehnaaz S. Khuroo and
  • Naira S. Khuroo

20 September 2016

Hepatitis E virus (HEV), an RNA virus of the Hepeviridae family, has marked heterogeneity. While all five HEV genotypes can cause human infections, genotypes HEV-1 and -2 infect humans alone, genotypes HEV-3 and -4 primarily infect pigs, boars and de...

  • Article
  • Open Access
4 Citations
2,868 Views
20 Pages

27 July 2023

Agricultural trade, which involves the exchange of virtual water and land resources, can effectively regulate the allocation of resources among countries while enhancing the well-being of resource-rich and resource-poor nations. China’s animal...

  • Review
  • Open Access
20 Citations
8,072 Views
15 Pages

The application of modern PCR approaches for the diagnosis of bacterial gastrointestinal pathogens is on the rise due to their rapidly available results combined with high sensitivity. While multiple studies describe the ongoing implementation of thi...

  • Review
  • Open Access
295 Citations
24,534 Views
9 Pages

17 September 2021

In December 2019, a new and highly pathogenic coronavirus emerged—coronavirus disease 2019 (COVID-19), a disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), quickly spread throughout the world. In response to this global p...

  • Article
  • Open Access
23 Citations
9,047 Views
17 Pages

17 June 2022

The high therapeutic effect of targeted radioisotope/radionuclide therapy (TRT) using α-emitters, especially 225Ac, is attracting attention worldwide. However, the only 225Ac production method that has been put into practical use is extraction...

  • Article
  • Open Access
26 Citations
5,205 Views
10 Pages

Media Access is Associated with Knowledge of Optimal Water, Sanitation and Hygiene Practices in Tanzania

  • Chelsi C. Alexander,
  • Shilpa Shrestha,
  • Mamadou D. Tounkara,
  • Shelly Cooper,
  • Leiema Hunt,
  • Taylor H. Hoj,
  • Kirk Dearden,
  • Dotto Kezakubi,
  • Vianney Atugonza and
  • Cougar Hall
  • + 1 author

The importance of water, sanitation and hygiene (WASH) behaviors in low- and middle-income countries in preventing childhood illness is well established. Tanzania is known to have high rates of chronic malnutrition and childhood stunting—both o...

  • Review
  • Open Access
32 Citations
15,398 Views
31 Pages

Agri-Food Markets in Qatar: Drivers, Trends, and Policy Responses

  • Tarek Ben Hassen,
  • Hamid El Bilali and
  • Mohammed Al-Maadeed

Agri-food markets are vital in achieving food security, especially for resource-poor, food-importing countries such as Qatar. The paper provides an overview of the evolution of agri-food markets in Qatar and explores the implications of past and ongo...

  • Review
  • Open Access
52 Citations
8,103 Views
30 Pages

Towards Exploitation of Adaptive Traits for Climate-Resilient Smart Pulses

  • Jitendra Kumar,
  • Arbind K. Choudhary,
  • Debjyoti Sen Gupta and
  • Shiv Kumar

Pulses are the main source of protein and minerals in the vegetarian diet. These are primarily cultivated on marginal lands with few inputs in several resource-poor countries of the world, including several in South Asia. Their cultivation in resourc...

  • Viewpoint
  • Open Access
3 Citations
2,695 Views
11 Pages

12 June 2022

Identification of germline pathogenic variants (PV) predisposing to Lynch syndrome (LS) is an important step for effective use of cascade screening of extended at-risk lineages, leading to reduced morbidity and mortality due to colorectal cancer (CRC...

  • Article
  • Open Access
50 Citations
9,739 Views
15 Pages

The use of indoor, three-stone fire pits in resource–poor countries is a substantial burden on human health and the environment. We conducted a pilot intervention promoting the purchase and use of an improved cookstove in rural Kenya. The goals of th...

  • Article
  • Open Access
1,049 Views
17 Pages

Rural and remote communities often face significant challenges maintaining their health and well-being. In developing countries, these challenges are further compounded by (1) limited access to clean water, (2) ineffective sanitation, (3) low educati...

  • Article
  • Open Access
7 Citations
5,238 Views
14 Pages

Despite the goal of eliminating new human immunodeficiency virus (HIV) infections in children, mother-to-child transmission is still common in resource-poor countries. The aims of this study were to assess the occurrence of mother-to-child transmissi...

  • Review
  • Open Access
20 Citations
7,597 Views
24 Pages

Enzyme-Assisted Nucleic Acid Amplification in Molecular Diagnosis: A Review

  • Meiling Wang,
  • Hongna Liu,
  • Jie Ren,
  • Yunqi Huang,
  • Yan Deng,
  • Yuan Liu,
  • Zhu Chen,
  • Franklin Wang-Ngai Chow,
  • Polly Hang-Mei Leung and
  • Song Li

19 January 2023

Infectious diseases and tumors have become the biggest medical challenges in the 21st century. They are driven by multiple factors such as population growth, aging, climate change, genetic predispositions and more. Nucleic acid amplification technolo...

  • Article
  • Open Access
35 Citations
4,460 Views
16 Pages

25 June 2020

Electrowetting on dielectric-based digital microfluidic platforms (EWOD-DMF) have a potential to impact point-of-care diagnostics. Conventionally, EWOD-DMF platforms are manufactured in cleanrooms by expert technicians using costly and time consuming...

  • Article
  • Open Access
3 Citations
2,466 Views
21 Pages

25 May 2023

The development of differentiated emission reduction strategies plays an important role in achieving carbon compliance targets. Each city should adopt carbon reduction strategies according to its carbon emission characteristics. China is a vast count...

  • Review
  • Open Access
6 Citations
1,389 Views
18 Pages

26 June 2025

After decades of calls for more sustainable land use systems, there is still a lack of consensus on an appropriate way forward, especially for tropical and subtropical agroecosystems. Land Maxing utilises appropriate, community-based interventions to...

  • Article
  • Open Access
16 Citations
6,824 Views
14 Pages

Affordability, Accessibility, and Awareness in the Adoption of Liquefied Petroleum Gas: A Case-Control Study in Rural India

  • Praveen Kumar,
  • Robert Ethan Dover,
  • Antonia Díaz-Valdés Iriarte,
  • Smitha Rao,
  • Romina Garakani,
  • Sophia Hadingham,
  • Amar Dhand,
  • Rachel G. Tabak,
  • Ross C. Brownson and
  • Gautam N. Yadama

11 June 2020

Interventions in the clean cooking sector have focused on improved biomass stoves in a bid to address household air pollution (HAP) in low- and middle-income countries. These initiatives have not delivered adequate health and environmental benefits o...

  • Article
  • Open Access
2 Citations
1,522 Views
13 Pages

Parental Reports on Late Effects and Follow-Up Needs: A Single-Center Assessment of Childhood Cancer Survivorship Care in Kenya

  • Susan Nyabate Mageto,
  • Jesse P. M. Lemmen,
  • Festus Muigai Njuguna,
  • Nancy Midiwo,
  • Sandra Cheptoo Langat,
  • Terry Allan Vik and
  • Gertjan J. L. Kaspers

The WHO Global Initiative for Childhood Cancer will likely increase the number of childhood cancer survivors in resource-poor countries. This study explored survivorship care in Kenya through parental reports on late effects and the follow-up needs o...

  • Article
  • Open Access
4 Citations
6,808 Views
22 Pages

14 December 2024

Farmer’s incentive is a core issue in achieving sustainable agricultural development. In many developing countries, smallholder farming is predominant in agricultural production, potentially limiting improvements in agricultural sustainability....

  • Review
  • Open Access
99 Citations
18,176 Views
20 Pages

Loop-Mediated Isothermal Amplification (LAMP) for the Diagnosis of Zika Virus: A Review

  • Severino Jefferson Ribeiro da Silva,
  • Keith Pardee and
  • Lindomar Pena

23 December 2019

The recent outbreak of Zika virus (ZIKV) in the Americas and its devastating developmental and neurological manifestations has prompted the development of field-based diagnostics that are rapid, reliable, handheld, specific, sensitive, and inexpensiv...

  • Concept Paper
  • Open Access
6 Citations
4,379 Views
14 Pages

19 July 2018

The United Nations’ One Health initiative advocates the collaboration of multiple sectors within the global and local health authorities toward the goal of better public health management outcomes. The emerging global health threat posed by Asp...

  • Review
  • Open Access
13 Citations
11,372 Views
56 Pages

Plant-Derived Anti-Cancer Therapeutics and Biopharmaceuticals

  • Ghyda Murad Hashim,
  • Mehdi Shahgolzari,
  • Kathleen Hefferon,
  • Afagh Yavari and
  • Srividhya Venkataraman

In spite of significant advancements in diagnosis and treatment, cancer remains one of the major threats to human health due to its ability to cause disease with high morbidity and mortality. A multifactorial and multitargeted approach is required to...

  • Article
  • Open Access
13 Citations
4,329 Views
17 Pages

25 February 2022

This paper intends to propose options for climate neutrality concepts by taking non-German international experiences and decisions made into account. Asia-Pacific and Arabic countries do have already same lessons learned by large-scale projects with...

  • Article
  • Open Access
2,206 Views
12 Pages

The national prevalence of HIV among adults in Zimbabwe was 10.4% in 2023, while the HIV prevalence in Bulawayo Metropolitan Province was 11.7%. The country achieved the UNAIDS Fast Track goals of 95-95-95 ahead of the 2030 target, by reporting an AR...

  • Article
  • Open Access
1 Citations
4,586 Views
13 Pages

A Diagnostic Model to Predict SARS-CoV-2 Positivity in Emergency Department Using Routine Admission Hematological Parameters

  • Rossana Soloperto,
  • Giovanna Guiotto,
  • Giuseppe Tozzi,
  • Maurizio Fumi and
  • Angelo Tozzi

Early detection of SARS-CoV-2 in the emergency department (ED) is a crucial necessity, especially in settings of overcrowding: establishing a pre-diagnostic test probability of infection would help to triage patients and reduce diagnostic errors, and...

  • Systematic Review
  • Open Access
19 Citations
9,094 Views
19 Pages

Post Discharge mHealth and Teach-Back Communication Effectiveness on Hospital Readmissions: A Systematic Review

  • Syed Fawad Mashhadi,
  • Aliya Hisam,
  • Siham Sikander,
  • Mommana Ali Rathore,
  • Faisal Rifaq,
  • Shahzad Ali Khan and
  • Assad Hafeez

Hospital readmissions pose a threat to the constrained health resources, especially in resource-poor low-and middle-income countries. In such scenarios, appropriate technologies to reduce avoidable readmissions in hospitals require innovative interve...

  • Article
  • Open Access
8 Citations
4,368 Views
16 Pages

Farmers’ Participation in Modern Supply Chains: The Case of Mandarin Profitability in Punjab-Pakistan

  • Rabia Mazhar,
  • Bi Xuehao,
  • Ants-Hannes Viira,
  • Ivana Janeska Stamenkovska,
  • Marina Nacka,
  • Hossein Azadi and
  • Zou Wei

In developing countries, supply chains are rapidly transforming. However, smallholder farmers, in particular, have experienced mixed impacts in inclusion and exclusion from modern supply chains (MSC). Therefore, by taking Pakistan’s mandarin in...

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