A reference electrode is a half-cell (an electrode) with a stable, well-defined and highly reproducible electrode potential. A vast number of electrodes have been developed for different applications. They are briefly presented. For the common types,...
Over the past two decades, there has been an increasing trend towards miniaturization of both biological and chemical sensors and their integration with miniaturized sample pre-processing and analysis systems. These miniaturized lab-on-chip devices h...
In this study, the performance and long-time evaluation of solid-state composite (SSC) reference electrodes were investigated. The stability of all the SSC reference electrodes was continuously monitored by using potentiometry and electrochemical imp...
Several types of liquid membrane and solid-state reference electrodes based on different plastics were fabricated. In the membranes studied, equitransferent organic (QB) and inorganic salts (KCl) are dispersed in polyvinyl chloride (PVC), polyurethan...
Different types of Ag/AgCl reference electrodes have been realised by means of thin- and thick-film technique. For inner electrolyte, KCl-containing membranes have been deposited and different coatings have been used to protect the reference electrod...
Use of a reference electrode (RE) in Li-ion batteries (LIBs) aims to enable quantitative evaluation of various electrochemical aspects of operation such as: (i) the distinct contribution of each cell component to the overall battery performance, (ii)...
To achieve a transition from conventional liquid-junction reference electrodes (LJF REs) to their all-solid-state alternatives, organic electrolytes are often introduced into the polymeric electrode membranes. In this article, we implement a theoreti...
In this study, a range of miniaturized Ag/AgCl reference electrodes with various layouts were successfully fabricated on wafer-level silicon-based substrates with metallic intermediate layers by precisely controlling the electrochemical deposition of...
Auditory brainstem response (ABR) peak measures were compared for a custom ear canal electrode and traditional mastoid and ear lobe reference electrode sites with the assumption that the ear canal electrode would yield larger Wave I amplitudes. In th...
Lab-on-Chip is a technology that could potentially revolutionize medical Point-of-Care diagnostics. Considerable research effort is focused towards innovating production technologies that will make commercial upscaling financially viable. Printed ci...
Currently, Ag/AgCl-based reference electrodes are used in most electrochemical biosensors and other bioelectrochemical devices. However, standard reference electrodes are rather large and do not always fit within electrochemical cells designed for th...
This work presents a flexible miniaturized ion-selective sensor consisting of a solid-contact reference electrode (RE) and ion-selective electrodes (ISE) fabricated on the same foil. The flexible ion sensor was based on AgCl electrodes screen printed...
A new class of solid-state miniaturised reference electrodes with a deep eutectic solvent as an alternate enhancement electrode system is described. A simple and accurate stable electrochemical sensor was prepared by developing a conventional referen...
Electrochemical aptamer-based sensors offer reagent-free and continuous analyte measurement but often suffer from poor longevity and potential drift even with a robust 3-electrode system. Presented here is a simple, software-enabled approach that tra...
A reference electrode is necessary for the working of ion-sensitive field-effect transistor (ISFET)-type sensors in electrolyte solutions. The Ag/AgCl electrode is normally used as a reference electrode. However, the Ag/AgCl reference electrode limit...
Processes’ occurring at the Ag/AgCl/Cl–, ([Fe(CN)6]3–/4–) ions interface study results are presented. Conditions are selected for the mixed salts’ precipitate formation on the silver surface. It has been shown that the potential of a silver screen-pr...
This work reports the design, synthesis, and characterization of a novel redox-active conjugated polyaniline containing quinone moiety as a solid state reference electrode. The union of electro-active quinone with π-conjugated polyaniline was crea...
We demonstrated a newly developed Ag/AgCl reference electrode- with a valve-actuator for two years or longer rumen pH monitoring. Previous studies on pH sensors reported that the short lifetime of Ag/AgCl reference electrodes is caused by an outflow...
Fused filament fabrication (FFF) is a 3D printing method that is attracting increased interest in the development of miniaturized electrochemical sensor systems due to its versatility, low cost, reproducibility, and capability for rapid prototyping....
Silicon nanowire field-effect transistors (Si NWFETs), thanks to their highly efficient integration into numerous electronic devices, represent promising tools for pH measurements and molecular biosensing due to their high sensitivity to ionic charge...
To improve the reference potential stability of on-chip amperometric sensors, we propose a novel integrated Ag/AgCl reference electrode structure. This structure can refresh the saturated potassium chloride filling solution surrounding the Ag/AgCl el...
In this study, we describe a novel solid-state thin-film Ag/AgCl reference electrode (SSRE) that was coated with a protective layer of graphene oxide (GO). This layer was prepared by drop casting a solution of GO on the Ag/AgCl thin film. The potenti...
The fabrication of miniaturized electrical biosensing devices can enable the rapid on-chip detection of biomarkers such as miRNA molecules, which is highly important in early-stage cancer detection. The challenge in realizing such devices remains in...
To evaluate the long term corrosion potential stability of stainless steel (SS) in environmental water, the corrosion potential of SUS304, SUS316, SUS316L, and SUS430 was measured for 1 week in a solution of 0.9 mM NaHCO3 and 0.5 mM CaCl2, referred t...
Silver materials are known to present excellent properties, such as high electrical and thermal conductivity as well as chemical stability. Silver-based inks have drawn a lot of attention for being compatible with various substrates, which can be use...
Ion-sensitive field-effect transistors (ISFETs) detect specific ions in solutions that enable straightforward, fast, and inexpensive sensors compared to other benchtop equipment. However, a conventional reference electrode (RE) such as Ag/AgCl is lim...
By combining traditional electrochemical tests including Tafel extension method and Mott-Schottky fitting, spectroscopic ellipsometry (SE) and a micro-region analysis technique, which is an integrated system of a scanning reference electrode techniqu...
Electrochemistry is ideally suited to serve as a detection mechanism in miniaturized analysis systems. A significant hurdle can, however, be the implementation of reliable micrometer-scale reference electrodes. In this tutorial review, we introduce t...
We present an innovative electrochemical probe for the monitoring of pH, redox potential and conductivity in near-field rocks of deep geological radioactive waste repositories. The probe is composed of a monocrystalline antimony electrode for pH sens...
Accurate potentiometric sensing critically depends on the stability and reproducibility of the reference electrode potential. Conventional liquid-filled Ag/AgCl or calomel electrodes, though well-established, are poorly compatible with miniaturized,...
Flexible iridium oxide (IrOx)-based micro-electrodes were fabricated on flexible polyimide substrates using a sol-gel deposition process for utilization as integrated pseudo-reference electrodes for bio-electrochemical sensing applications. The fabr...
Novel applications of online pH determinations at temperatures from -35 °C to 130 °C in technical and biological media, which are all but ideal aqueous solutions, require new approaches to pH monitoring. The glass electrode, introduced nearly hundred...
A reference electrode fabricated by means of thick-film technique is deposited onto a silicon substrate and combined with a thin-film pH sensor to a “hybrid” chip system. To evaluate the suitability of this combination, first investigations were carr...
The internal negative electrode potential in lithium-ion batteries (LIBs) is intricately linked to the lithium-ion intercalation and plating reactions occurring within the cell. With the expansion of cell sizes, the internal negative electrode potent...
This work summarizes the electrochemical response of a salicylic acid-based carbon electrode for use as a novel solid-state reference electrode in a redox-based pH sensor. This novel reference produces a pH insensitive response over a range of pH 3&n...
This paper reports a novel miniaturized pseudo reference electrode (RE) design for biasing Ion Sensitive Field Effect Transistors (ISFETs). It eliminates the need for post-CMOS processing and can scale up in numbers with the CMOS scaling. The present...
Intense interest in reference electrode design and fabrication has recently been enriched with the application of 3D printing of electrodes with salt-loaded PVC membranes. This type of material is attractive in sensor technology and is challenging to...
The monitoring of Na+ ions distributed in the body has been indirectly calculated by the detection of Na+ ions in urine. We fabricated a two–dimensional (2D) Na+ ion sensor using a graphene ion–sensitive field–effect transistor (G–ISFET) and used flu...
A corrosion sensor for monitoring the corrosion state of cover mortar was developed. The sensor was tested in cement mortar, with and without the addition of chloride to simulate the adverse effects of chloride-contaminated environmental conditions o...
Lithium plating can cause capacity fade and thermal runaway safety issues in lithium-ion batteries. Therefore, accurately detecting the amount of lithium plating on the surface of the battery’s negative electrode is crucial for battery safety....
This study aimed to determine the stability of refrigerated analytes of iMg concentration at different time intervals and to establish iMg reference range in a cohort of healthy Omani volunteers (≥18 years). The concentrations of iMg were measured...
The use of concentrated aprotic electrolytes in lithium batteries provides numerous potential applications, including the use of high-voltage cathodes and Li-metal anodes. In this paper, we aim at understanding the effect of salt concentration on the...
Abstract: We report the fabrication and characterisation of the first graphene ring micro electrodes with the addition of a miniature concentric Ag/AgCl reference electrode. The graphene ring electrode is formed by dip coating fibre optics with grap...
This work introduces a new method for inserting a Lithium reference electrode into commercially available 18650-type cells in order to obtain electrode potentials during cell operation. The proposed method is simple and requires limited equipment. Fu...
We present a reference-electrode free sensor able to measure both pH and conductivity
based on impedance spectroscopy. The electrode is made of a layer of indium-tin-oxide (ITO). The
impedance of this electrode at low frequencies depends on its double...
To realize an ultra-low-power and low-noise instrumentation amplifier (IA) for neural and biopotential signal sensing, we investigate two design techniques. The first technique uses a noise-efficient DC servo loop (DSL), which has been shown to be a...
A stable reference electrode (RE) plays a crucial role in the performance of an ion-sensitive field-effect transistor (ISFET) for bio/chemical sensing applications. There is a strong demand for the miniaturization of the RE for integrated sensor syst...
This work demonstrates the use of SUS316L stainless steel as a new material for the fabrication of quasi-reference electrodes (QREs) intended to replace conventional reference electrodes (REs) in electrochemical sensors. The present study examined th...
A pH-sensitive RuO2 electrode coated in a commercial cyanoacrylate adhesive typically exhibits very low pH sensitivity, and could be paired with a RuO2 working electrode as a differential type pH sensor. However, such sensors display poor performance...
We present a flexible pH sensor which leverages the unique properties of reduced graphene oxide/polyaniline (rGO/PANI) composite films through an efficient and scalable hybrid microfabrication approach, wherein the rGO/PANI films are conformally coat...
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